WO2008072985A3 - Pour on formulation - Google Patents

Pour on formulation Download PDF

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Publication number
WO2008072985A3
WO2008072985A3 PCT/NZ2007/000360 NZ2007000360W WO2008072985A3 WO 2008072985 A3 WO2008072985 A3 WO 2008072985A3 NZ 2007000360 W NZ2007000360 W NZ 2007000360W WO 2008072985 A3 WO2008072985 A3 WO 2008072985A3
Authority
WO
WIPO (PCT)
Prior art keywords
formulation
pour
storage stable
anthelmintic activity
compounds
Prior art date
Application number
PCT/NZ2007/000360
Other languages
French (fr)
Other versions
WO2008072985A2 (en
Inventor
Kathigeyan Nanjan
Fadil Al Alawi
Original Assignee
Bomac Research Ltd
Kathigeyan Nanjan
Fadil Al Alawi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bomac Research Ltd, Kathigeyan Nanjan, Fadil Al Alawi filed Critical Bomac Research Ltd
Priority to BRPI0720102-8A priority Critical patent/BRPI0720102A2/en
Priority to AU2007332222A priority patent/AU2007332222C1/en
Publication of WO2008072985A2 publication Critical patent/WO2008072985A2/en
Publication of WO2008072985A3 publication Critical patent/WO2008072985A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a storage stable pour on formulation. containing one or more macrocyclic compounds with anthelmintic activity along with a glyceryl acetate solvent including triacetin. The formulation may also include other compounds with anthelmintic activity and still remain storage stable.
PCT/NZ2007/000360 2006-12-13 2007-12-13 Pour on formulation WO2008072985A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0720102-8A BRPI0720102A2 (en) 2006-12-13 2007-12-13 FORMULATION OF DEPOSITION
AU2007332222A AU2007332222C1 (en) 2006-12-13 2007-12-13 Pour on formulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ552040A NZ552040A (en) 2006-12-13 2006-12-13 Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
NZ552040 2006-12-13

Publications (2)

Publication Number Publication Date
WO2008072985A2 WO2008072985A2 (en) 2008-06-19
WO2008072985A3 true WO2008072985A3 (en) 2008-08-28

Family

ID=39512205

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NZ2007/000360 WO2008072985A2 (en) 2006-12-13 2007-12-13 Pour on formulation

Country Status (4)

Country Link
AU (1) AU2007332222C1 (en)
BR (1) BRPI0720102A2 (en)
NZ (1) NZ552040A (en)
WO (1) WO2008072985A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011027333A1 (en) 2009-09-07 2011-03-10 Douglas Robert Cleverly Granulated anthelmintic preparations and delivery systems
AR081970A1 (en) * 2010-06-24 2012-10-31 Intervet Int Bv INJECTABLE FORMULATION OF A MACROCICLIC AND LEVAMISOL LACTONE, FORMULATION AND VETERINARY USE
JP6120834B2 (en) 2011-06-23 2017-04-26 バイエル・ニュージーランド・リミテッド Antiparasitic compositions comprising macrocyclic lactones and levamisole, and methods of treating parasitic infections
FR2991173B1 (en) * 2012-06-04 2015-11-06 Virbac VETERINARY COMPOSITION WITH OXYCLOZANIDE BASED SKIN ADMINISTRATION
WO2014132227A1 (en) * 2013-02-27 2014-09-04 Batt Laurie Robert Transdermal formulations
CN103432152A (en) * 2013-08-22 2013-12-11 潍坊富邦药业有限公司 Injection for repelling and killing internal and external parasites of livestock
NZ701697A (en) * 2014-03-24 2016-05-27 Donaghys Ltd Stable veterinary anthelmintic formulations
EP3393455B1 (en) * 2015-12-22 2021-07-21 Intervet International B.V. Injectable formulation of a macrocyclic lactone and levamisole

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978675A (en) * 1985-04-30 1990-12-18 American Cyanamid Company Macrolide antibiotics and their preparation
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles
EP0413538B1 (en) * 1989-08-14 1993-10-13 Merck & Co. Inc. Long active injectable formulations containing triacetin
WO1994026113A2 (en) * 1993-05-10 1994-11-24 Merck & Co., Inc. Pour-on formulations containinng polymeric material, glycols and glycerides
EP0535734B1 (en) * 1991-09-30 1999-06-02 Merck & Co. Inc. Long acting injectable formulations containing hydrogenated castor oil
WO1999027906A1 (en) * 1997-12-03 1999-06-10 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated castor oil
WO1999047073A1 (en) * 1998-03-19 1999-09-23 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
WO2000061068A2 (en) * 1999-04-14 2000-10-19 Ashmont Holdings Limited Anthelmintic compositions
WO2001060409A1 (en) * 2000-02-16 2001-08-23 Merial Limited Improved paste formulations
CN1421199A (en) * 2001-11-29 2003-06-04 王玉万 Veterinary emulsion injection containing parasiticide prepared via micropowder crystallization process
WO2003086469A1 (en) * 2002-03-19 2003-10-23 Eco Animal Health Ltd Ethyl cellulose-containing veterinary sustained release injection
WO2004009080A1 (en) * 2002-07-19 2004-01-29 Ashmont Holdings Limited Levamisole, Avermectins or similar in pyrrolidone solvent
CN1698636A (en) * 2004-05-17 2005-11-23 王玉万 Mixing method of antiparasitic preparation for animals

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978675A (en) * 1985-04-30 1990-12-18 American Cyanamid Company Macrolide antibiotics and their preparation
EP0413538B1 (en) * 1989-08-14 1993-10-13 Merck & Co. Inc. Long active injectable formulations containing triacetin
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles
EP0535734B1 (en) * 1991-09-30 1999-06-02 Merck & Co. Inc. Long acting injectable formulations containing hydrogenated castor oil
WO1994026113A2 (en) * 1993-05-10 1994-11-24 Merck & Co., Inc. Pour-on formulations containinng polymeric material, glycols and glycerides
WO1999027906A1 (en) * 1997-12-03 1999-06-10 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated castor oil
WO1999047073A1 (en) * 1998-03-19 1999-09-23 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
WO2000061068A2 (en) * 1999-04-14 2000-10-19 Ashmont Holdings Limited Anthelmintic compositions
WO2001060409A1 (en) * 2000-02-16 2001-08-23 Merial Limited Improved paste formulations
CN1421199A (en) * 2001-11-29 2003-06-04 王玉万 Veterinary emulsion injection containing parasiticide prepared via micropowder crystallization process
WO2003086469A1 (en) * 2002-03-19 2003-10-23 Eco Animal Health Ltd Ethyl cellulose-containing veterinary sustained release injection
WO2004009080A1 (en) * 2002-07-19 2004-01-29 Ashmont Holdings Limited Levamisole, Avermectins or similar in pyrrolidone solvent
CN1698636A (en) * 2004-05-17 2005-11-23 王玉万 Mixing method of antiparasitic preparation for animals

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 143, Columbus, Ohio, US; abstract no. 103282, WANG Y. ET AL.: "Micropowder crystallization method for preparing veterinary injection of antiparasitic agent oily suspension" *
CHEMICAL ABSTRACTS, vol. 145, Columbus, Ohio, US; abstract no. 299554, WANG Y. ET AL.: "Combined application method of veterinary antiparasitic drugs" *
DATABASE WPI Week 200382, Derwent World Patents Index; Class A96, AN 2003-903075 *

Also Published As

Publication number Publication date
AU2007332222C1 (en) 2014-06-26
NZ552040A (en) 2009-04-30
AU2007332222A1 (en) 2008-06-19
AU2007332222B2 (en) 2013-01-17
BRPI0720102A2 (en) 2014-07-08
WO2008072985A2 (en) 2008-06-19

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