WO2008068777A3 - Formulation stable de lercanidipine - Google Patents
Formulation stable de lercanidipine Download PDFInfo
- Publication number
- WO2008068777A3 WO2008068777A3 PCT/IN2007/000585 IN2007000585W WO2008068777A3 WO 2008068777 A3 WO2008068777 A3 WO 2008068777A3 IN 2007000585 W IN2007000585 W IN 2007000585W WO 2008068777 A3 WO2008068777 A3 WO 2008068777A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lercanidipine
- stable
- adsorbates
- formulation
- lercanidipine formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention porte sur une forme posologique orale solide stable de lercanidipine à l'aide d'un procédé de préparation d'adsorbats. L'invention porte en outre sur des adsorbats de lercanidipine qui peuvent être obtenus par ledit procédé, ainsi que sur des formulations pharmaceutiques préparées avec lesdits adsorbats de lercanidipine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07870544A EP2101771A2 (fr) | 2006-12-06 | 2007-12-05 | Formulation stable de lercanidipine |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2004MU2006 | 2006-12-06 | ||
IN2004/MUM/2006 | 2006-12-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008068777A2 WO2008068777A2 (fr) | 2008-06-12 |
WO2008068777A3 true WO2008068777A3 (fr) | 2008-12-31 |
Family
ID=39363963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2007/000585 WO2008068777A2 (fr) | 2006-12-06 | 2007-12-05 | Formulation stable de lercanidipine |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2101771A2 (fr) |
WO (1) | WO2008068777A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2010000856A (es) * | 2007-07-23 | 2010-04-30 | Pharmathen Sa | Composicion farmaceutica que contiene un antagonista del canal de calcio de tipo dihidropiridina y metodo para la preparacion de la misma. |
SI2585051T2 (sl) | 2010-06-23 | 2020-07-31 | Krka, D.D., Novo Mesto | Farmacevtske oralne odmerne oblike,ki obsegajo lerkanidipin in enalapril in njune farmacevtsko sprejemljive soli |
SI2654729T1 (sl) | 2010-12-24 | 2016-08-31 | Krka, D.D., Novo Mesto | Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5266581A (en) * | 1984-07-04 | 1993-11-30 | Bayer Aktiengesellschaft | Solid composition containing dihydropyridine, PVP and PVPP |
US20060134212A1 (en) * | 2004-09-02 | 2006-06-22 | Forest Laboratories, Inc. | Lercanidipine immediate release compositions |
US20060211742A1 (en) * | 2005-02-25 | 2006-09-21 | Recordati Ireland Limited | Amorphous lercanidipine hydrochloride and uses thereof |
-
2007
- 2007-12-05 EP EP07870544A patent/EP2101771A2/fr not_active Withdrawn
- 2007-12-05 WO PCT/IN2007/000585 patent/WO2008068777A2/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5266581A (en) * | 1984-07-04 | 1993-11-30 | Bayer Aktiengesellschaft | Solid composition containing dihydropyridine, PVP and PVPP |
US20060134212A1 (en) * | 2004-09-02 | 2006-06-22 | Forest Laboratories, Inc. | Lercanidipine immediate release compositions |
US20060211742A1 (en) * | 2005-02-25 | 2006-09-21 | Recordati Ireland Limited | Amorphous lercanidipine hydrochloride and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2008068777A2 (fr) | 2008-06-12 |
EP2101771A2 (fr) | 2009-09-23 |
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