WO2008067384A2 - Visceral anchors for purse-string closure of perforations - Google Patents

Visceral anchors for purse-string closure of perforations Download PDF

Info

Publication number
WO2008067384A2
WO2008067384A2 PCT/US2007/085769 US2007085769W WO2008067384A2 WO 2008067384 A2 WO2008067384 A2 WO 2008067384A2 US 2007085769 W US2007085769 W US 2007085769W WO 2008067384 A2 WO2008067384 A2 WO 2008067384A2
Authority
WO
WIPO (PCT)
Prior art keywords
visceral
suture
anchor
perforation
anchors
Prior art date
Application number
PCT/US2007/085769
Other languages
French (fr)
Other versions
WO2008067384A3 (en
Inventor
Vihar C. Surti
David Desilets
Original Assignee
Wilson-Cook Medical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wilson-Cook Medical, Inc. filed Critical Wilson-Cook Medical, Inc.
Priority to CA2671030A priority Critical patent/CA2671030C/en
Priority to EP07868914A priority patent/EP2094167B1/en
Priority to JP2009539460A priority patent/JP5270565B2/en
Priority to AT07868914T priority patent/ATE514382T1/en
Priority to AU2007325204A priority patent/AU2007325204B2/en
Publication of WO2008067384A2 publication Critical patent/WO2008067384A2/en
Publication of WO2008067384A3 publication Critical patent/WO2008067384A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00637—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0409—Instruments for applying suture anchors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0414—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having a suture-receiving opening, e.g. lateral opening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0417—T-fasteners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
    • A61B2017/0454—Means for attaching and blocking the suture in the suture anchor the anchor being crimped or clamped on the suture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
    • A61B2017/0458—Longitudinal through hole, e.g. suture blocked by a distal suture knot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0464—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors for soft tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B2017/1142—Purse-string sutures

Definitions

  • the present invention relates generally to visceral anchors for connecting a suture to tissue, and more particularly relates to using visceral anchors and suture to close perforations in tissue.
  • Perforations in bodily walls may be naturally occurring, or formed intentionally or unintentionally.
  • numerous medical devices and methods have been developed employing sutures, adhesives, clips, staples and the like.
  • tissue anchors T-anchors
  • visceral anchors An exemplary visceral 'anchor is disclosed in U.S. Pat. No. 5,123,914, the entire contents of which are incorporated by reference herein.
  • Such visceral anchors have been very successful in medical procedures requiring visceral wall mobilization or wall apposition.
  • J perforations are not without their drawbacks.
  • all of the individual sutures connected to the anchors must be collected and connected together. It can often be difficult to properly tension each of the individual sutures to ensure proper approximation of the tissue around the perforation and complete closure thereof. This is especially critical within the gastrointestinal tract, where the travel of bacteria laden fluids outside of the tract may cause unwanted and sometimes deadly infection.
  • the present invention provides- medical devices and related methods for closing a perforation in a bodily wall that provides reliable and complete closure of perforations, while at the same time gives increased versatility and control over perforation closure.
  • a medical device constructed in accordance with the teachings of the present invention, generally comprises a suture having opposing first and second ends and a set of visceral anchors.
  • Each visceral anchor includes a crossbar having opposing ends, and a suture is slidably attached to the crossbar.
  • the first and second ends of the suture are capable of being independently tensioned for translating the suture relative to each of the visceral anchors and closing the perforation.
  • the tensioning of the suture reduces the distance between the visceral anchors to close the perforation in a purse-string fashion.
  • the tensioning of the suture causes compression of the bodily wall around the perforation.
  • Each visceral anchor is positioned on one side of the bodily wall, and first and second ends of the suture are positioned on the opposite side of the bodily wall.
  • the medical device may further include an overtube for delivery of the set of visceral anchors.
  • the overtube has a set of lumens, each lumen receiving a visceral anchor. Portions of the suture located between the visceral anchors extend outside the lumens at a distal end of the overtube.
  • the medical device may also include a set of puncture needles slidably received within the set of lumens, the set of puncture needles receiving the set of visceral anchors therein.
  • a visceral anchor constructed in accordance with the teachings of the present invention, generally comprises a crossbar having a passageway.
  • the crossbar has first and second opposing ends and defines a longitudinal axis.
  • the passageway is located between the opposing ends of the crossbar and slidably receives the suture therein.
  • the passageway has an entrance and an exit through which the suture passes.
  • the entrance and exit are spaced apart a distance greater than 0.001 mm and less than 1.0 mm.
  • the passageway may extend parallel to the longitudinal axis of perpendicular to the longitudinal axis.
  • the crossbar is constructed of a cannula having a tubular wall defining a lumen.
  • a first opening in the wall defines the entrance and a second opening in the wall defines the exit.
  • the first opening may take the form a first longitudinal slot formed in the first end of the cannula and the second opening is likewise a second longitudinal slot formed in the second end of the cannula.
  • the tubular wall includes a strip portion extending between the first and second slots.
  • the visceral anchor further comprises a loop, wherein the passageway is defined between the loop and the crossbar.
  • the loop is formed by a wire connected to the crossbar and projecting outwardly therefrom.
  • the crossbar is constructed of a cannula having a tubular wall defining a lumen
  • the tubular wall defines first and second openings and a first end of the wire is passed through the first opening and a second end of the wire is passed through the second opening.
  • the first and second ends of the wire are secured within the lumen of the cannula.
  • the loop is formed by a rod connected to the crossbar.
  • the rod is secured within the lumen of the cannula.
  • the tubular wall will define an opening in communication with the lumen to provide access to the rod.
  • the rod may extend parallel with the longitudinal axis or perpendicular to the longitudinal axis.
  • a method for closing a perforation in a bodily wall is provided in accordance with the teachings of the present invention.
  • the method utilizes a set of visceral anchors connected to a suture as previously described.
  • Each visceral anchor is passed through the bodily wall adjacent the periphery of the perforation.
  • Each visceral anchor is on a distal side of the bodily wall, while the ends of the suture on a proximal side of the bodily wall.
  • the ends of the suture are tensioned to reduce the distance between the visceral anchors and compress the bodily wall around the perforation.
  • the ends of the suture are secured to maintain the compression of the bodily wall and close the perforation.
  • the passing step includes positioning the set of visceral anchors around the perforation to permit closing of the perforation in a purse-string fashion.
  • the passing step preferably includes positioning the set of visceral anchors sequentially around the perforation in a semi- annular or annular shape.
  • the passing step includes positioning the set of visceral anchors sequentially in opposite sides of the perforation.
  • the tensioning steps preferably include independently tensioning the ends of the suture.
  • FIG. 1 is a front view of a visceral anchor constructed in accordance with the teachings of the present invention
  • FIG. 2 is a top view of the visceral anchor depicted in FIG. 1 ;
  • FIG. 3 is a cross-sectional view taken about the line 3-3 in FIG. 1 ;
  • FIG. 4 is a plan view schematically depicting a medical device constructed in accordance with the teachings of the present invention.
  • FIG. 5 is a cross-sectional view of the medical device depicted in FIG.
  • FIG. 6 is a schematic view of the medical device similar to FIG. 4 but showing the medical device closing a perforation
  • FIG. 7 is a cross-sectional view of the medical device as depicted in
  • FIG. 6 is a diagrammatic representation of FIG. 6
  • FIG. 8 is a perspective view, partially cutaway, depicting an overtube for deploying the medical device depicted in FIG. 4;
  • FIG. 9 is a perspective view of an alternate embodiment of a visceral anchor constructed in accordance with the teachings of the present invention.
  • FIG. 10 is a side view of the visceral anchor depicted in FIG. 9;
  • FIG. 11 is a plan view of another alternate embodiment of a visceral anchor constructed in accordance with the teachings of the present invention.
  • FIG. 12 is a cross-sectional view of the visceral anchor depicted in
  • FIG. 11 is a diagrammatic representation of FIG. 11 ;
  • FIG. 13 is a plan view of another alternate embodiment of a visceral anchor constructed in accordance with the teachings of the present invention.
  • FIG. 14 is a side view of the visceral anchor depicted in FIG. 13; and
  • FIG. 15 is a side view of the visceral anchor depicted in FIG. 13.
  • FIGS. 1-3 depict a visceral anchor 20 constructed in accordance with the teachings of the present invention.
  • the anchor 20 is utilized to connect a suture 22 to tissue for closing a perforation 10 in a bodily wall 12 (FIGS. 4 and 5).
  • the anchor 20 generally includes a crossbar 24 having opposing ends 26 and 28.
  • the crossbar 24 is preferably elongated, but may take any form suitable for connecting the suture 22 to the bodily wall 12.
  • the crossbar 24 is constructed of a cannula having a tubular wall 34 defining a lumen 36.
  • First and second apertures 38, 40 are formed in the tubular wall 34, and the wire 30 passes through the apertures 38, 40.
  • the ends of wire 30 are secured within the lumen 36 of the cannula by welds 44. It will be recognized by those skilled in the art that the wire 30 may be secured to the crossbar 24 using any now known or hereinafter developed attachment means, including mechanical fasteners, adhesives or various welding or soldering techniques.
  • the passageway 32 has an entrance 46 and an exit 48 through which the suture 22 passes.
  • the entrance and exit are spaced apart a very short distance so that the leading and trailing portions of the suture 22 may remain in close proximity, allowing the crossbar 24 to be pulled extremely close to the bodily wall 12 and ensuring good compression of the tissue and closure of the perforation 10.
  • the entrance and exit are spaced apart a distance less than an outer diameter of the crossbar 24, and more preferably a distance greater than 0.001 mm. and less than 1.0 mm.
  • the distance is defined by a diameter of the wire 30, and hence the wire 30 having a size in this range is selected for construction of the anchor 20.
  • the wire 30 results in limited friction between the wire 30 and suture 22, ensuring reliable operation for purse- string type closure of the perforation 10.
  • the wire 30 may also be coating with a hydrophilic coating or other material which aids in the reduction of friction.
  • the visceral anchors 20 are preferably deployed as a set of anchors 20a, 20b, 2Oc 1 2Od linked together by a single suture 22, all of which collectively forms a medical device 50 for closing the perforation 10 in the bodily wall 12.
  • the suture 22 is slidably connected to each of the visceral anchors 20a, 20b, 20c, and 20d, leaving two free ends 52, 54 of the suture 22 which may be independently tensioned to close the perforation 10.
  • the visceral anchors (20b and 20c depicted) are positioned on a distal side of the bodily wall 12, while the majority of suture 22 is positioned on a proximal side of the bodily wall 12, including the suture ends 52, 54. Accordingly, it will be recognized that the medical device 50 operates in a purse-string fashion to close the perforation 10 in the bodily wall, as will be described in more detail below.
  • a method of closing the perforation 10, in accordance with the teachings present invention includes passing each visceral anchor 20a, 20b, 20c, and 2Od through the bodily wall 12 adjacent the periphery of the perforation 10, as shown in FIG. 4.
  • the anchors are sequentially positioned around the perforation 10 in a semi-annular or annular shape as shown.
  • the ends 52, 54 of the suture are then tensioned to reduce the distance between the visceral anchors 20a, 20b, 20c, 2Od and compress the bodily wall 12 around the perforation 10, as depicted in FIGS. 6 and 7.
  • FIG. 6 and 7 As best seen in FIG.
  • the ends 52, 54 of the suture 22 are secured to maintain the compression of the bodily wall 10, such as through the use of a suture lock 56.
  • exemplary suture locks are disclosed in U.S. Patent Application Nos. 60/941 ,086 and 60/956,575, the disclosures of which are incorporated herein by reference in their entirety. It will be recognized that any now known or future developed method for securing the ends 52, 54 of the suture 22 may be employed, such as knotting, tying, clamps, rivets and the like.
  • One preferred delivery mechanism optionally forming a portion of the medical device 50 includes an overtube 60 having a set of lumens 61 , 62, 63, 64, i.e., one lumen for each visceral anchor 20 that is desired to be deployed.
  • Each lumen 61 , 62, 63, 64 extends through a distal end 65 of the overtube 60 and is sized to receive a puncture needled 58 therein.
  • a distal end of the puncture needle 58 receives a visceral anchor 20, and the leading and trailing portions of the suture 22 project distally from each anchor 20.
  • the interconnecting portions of the suture 22 i.e. between each anchor 20
  • the free ends 54, 56 of the suture 22 extend proximally along the interior of the overtube 60 (and hence proximally through the bodily lumen) and outside of the body.
  • the overtube 60 has an inner diameter D that is preferably sized to be about the same size or greater than the largest dimension of the perforation 10 in the bodily wall 12. Accordingly, it will be recognized that the overtube 60 may be positioned against the bodily wall 12 in a location that covers the perforation 10.
  • Each of the puncture needles 58 may be translated distally and passed through the bodily wall 12.
  • a plunger (not shown) is used to expel the visceral anchors 20 from the puncture needles 58 on the distal side of the bodily wall 12.
  • the puncturing needles 58 are then retracted, as is the overtube 60 to leave the crossbars 24 on the distal side of the bodily wall 12, while the suture 22 and its free ends 54,56 remain on the proximal ' side of the bodily wall12.
  • the entire set of visceral anchors may be simultaneously, deployed, or alternatively may be deployed in various combinations, " such as in pairs or individually, and in various sequences as need or desired. It will.also be recognized that placement of the set of anchors 20 may be aided by fluoroscopy, ultrasound or visually through the use of medical instruments having imaging capabilities such as an endoscope that is passed through the lumen of the overtube 60.
  • the overtube is preferably constructed of a .
  • plastic such as polytetrafluorethylene " (PTFE), expanded polytetrafluorethylene (EPTFE), polyethylene ether ketone (PEEK), polyvinylchloride (PVC), polycarbonate (PC), polyamide including nylon, polyimide, polyurethane, polyethylene - (high, medium or low density), and elastomers such as Santoprene(TM), including multi-layer or single layer constructions with or without reinforcement wires, coils or filaments.
  • PTFE polytetrafluorethylene
  • EPTFE expanded polytetrafluorethylene
  • PEEK polyethylene ether ketone
  • PVC polyvinylchloride
  • PC polycarbonate
  • polyamide including nylon
  • polyimide polyurethane
  • polyethylene - high, medium or low density
  • elastomers such as Santoprene(TM), including multi-layer or single layer constructions with or without reinforcement wires, coils or filaments.
  • FIGS. 9-14 depict various alternate embodiments of visceral anchors 120, 220, 320 that are constructed in accordance with the teachings of the present invention.
  • the visceral anchor 120 is again constructed of a crossbar 124 having opposing ends 126, 128 and defining a longitudinal axis.
  • the crossbar 124 is constructed of a cannula having a tubular wall 134 defining an interior lumen 136.
  • a first slot 140 is formed at the first end 126 of the cannula
  • a second slot 142 is formed at the second end 128 of the cannula.
  • the slots 140, 142 extend longitudinally and leave a centrally located strip portion 138 of the cannula.
  • the strip portion 138 in combination with the tubular wall 134, defines a passageway 132 therebetween for receiving a suture 22.
  • the distance between the entrance and exit of the passageway 132 is defined by the length of the strip portion 138.
  • the length of strip portion 138 may be sized larger than 1.0 mm, although it may also be smaller.
  • the passageway is preferably structured to reduce friction between the crossbar and suture, and ensure reliable translation of the anchor relative to the suture. This may be accomplished by eliminating sharp edges, and/or utilizing a hydrophilic coating or other low-friction materials.
  • the visceral anchor 220 includes a crossbar 224 having opposing ends 226, 228 and defining a longitudinal axis.
  • the crossbar 224 is constructed of a cannula having a tubular wall 234 defining an interior lumen 236.
  • a rod 230 is fitted inside the interior lumen 236.
  • the rod 230 extends parallel to the longitudinal axis and is secured to the ends 226, 228 of the crossbar 224, such as by welds 244.
  • any now known or hereinafter developed connection means may be employed for the rod 230, such as those previously described for the wire 30.
  • An opening 238 is formed in the tubular wall 234 of the crossbar 224 to provide access to the lumen 236 and the rod 230. It will therefore be seen that a passageway 232 is formed by the portion of the lumen 236 located between the rod 230 and tubular wall 234. Here, the distance between the entrance and exit of the passageway 232 is defined by a diameter or width of the rod 230.
  • yet another embodiment of a visceral anchor 320 includes a crossbar 324 having opposing ends 326, 328 and defining a longitudinal axis.
  • the crossbar 324 is constructed from a cannula having a tubular wall 234 defining a lumen 336.
  • a rod 330 is again positioned within the lumen 336, and an opening 338 in the tubular wall 334 provides access to, the loop and rod 330.
  • the rod 330 is disposed generally perpendicular to the longitudinal axis and is connected to the tubular wall 334, such as by welds 344.
  • a passageway 332 is formed by the portion of the lumen 336 located between the rod 330 and tubular wall 334. The distance between the entrance and exit of the passageway 332 is defined by the diameter or width of the rod 330.
  • a separately formed rod 230, 330 has been depicted as attached to the crossbar 224, 324.
  • the rods or any other loop structures may be integrally and/or unitarily formed with the crossbar, such as by metal injection molding, casting and the like, as well as by material removal techniques such as laser-cutting, blasting, grinding and the like.
  • visceral anchors may also be passed through the bodily wall 1-2 and orientated relative to one another in numerous ways.
  • the set of visceral anchors 20a, 20b, 20c, 2Od have been placed on opposing sides of a generally linear perforation 10. More specifically, the visceral anchors 20a, 20b, 20c, 2Od have been sequentially positioned on opposite sides of the perforation 10 in a zig-zag configuration.
  • any number of visceral anchors 20 may be employed, they may be placed in any order and in virtually any configuration.
  • the anchors may criss-cross back and forth and over each other and overlap.
  • each anchor 20 within a set of anchors permits the anchors 20 to be spaced apart any desired distance, providing increased flexibility in their orientation.
  • both ends 52, 54 of the suture 22 may be independently adjusted or simultaneously adjusted to draw the anchors 20 closer together and close the perforation through compression of the tissue.
  • the ability to pass sutures completely through the bodily wall 12 while retaining a purse-string type " closure improves the compression that may be induced on the bodily wall 12 toward the perforation 10 to ensure a secure and tight closure.

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

Medical devices and related methods for closing a perforation in a bodily wall The medical device generally includes a suture having opposing first and second ends and a set of visceral anchors. Each visceral anchor includes a crossbar having opposing ends and a suture slidably attached thereto. Each visceral anchor is passed through the bodily wall adjacent the periphery of the perforation. The ends of the suture are tensioned to reduce the distance between the visceral anchors and compress the bodily wall around the perforation. The ends of the suture are secured to maintain the compression of the bodily wall and close the perforation.

Description

VISCERAL ANCHORS FOR PURSE-STRING CLOSURE OF PERFORATIONS
FIELD OF THE INVENTION
[0001] The present invention relates generally to visceral anchors for connecting a suture to tissue, and more particularly relates to using visceral anchors and suture to close perforations in tissue.
BACKGROUND OF THE INVENTION
[0002] Perforations in bodily walls may be naturally occurring, or formed intentionally or unintentionally. In order to permanently close these perforations and allow the tissue to properly heal, numerous medical devices and methods have been developed employing sutures, adhesives, clips, staples and the like. One class of such devices is commonly referred to as tissue anchors (T-anchors) or visceral anchors. An exemplary visceral 'anchor is disclosed in U.S. Pat. No. 5,123,914, the entire contents of which are incorporated by reference herein. Such visceral anchors have been very successful in medical procedures requiring visceral wall mobilization or wall apposition.
[0003] Visceral anchors have also been successfully used in closing
J perforations, but are not without their drawbacks. For example, when a series of anchors are placed around a perforation, all of the individual sutures connected to the anchors must be collected and connected together. It can often be difficult to properly tension each of the individual sutures to ensure proper approximation of the tissue around the perforation and complete closure thereof. This is especially critical within the gastrointestinal tract, where the travel of bacteria laden fluids outside of the tract may cause unwanted and sometimes deadly infection.
BRIEF SUMMARY OF THE INVENTION
[0004] The present invention provides- medical devices and related methods for closing a perforation in a bodily wall that provides reliable and complete closure of perforations, while at the same time gives increased versatility and control over perforation closure. One embodiment of a medical device, constructed in accordance with the teachings of the present invention, generally comprises a suture having opposing first and second ends and a set of visceral anchors. Each visceral anchor includes a crossbar having opposing ends, and a suture is slidably attached to the crossbar. The first and second ends of the suture are capable of being independently tensioned for translating the suture relative to each of the visceral anchors and closing the perforation.
[0005] According to more detailed aspects, the tensioning of the suture reduces the distance between the visceral anchors to close the perforation in a purse-string fashion. The tensioning of the suture causes compression of the bodily wall around the perforation. Each visceral anchor is positioned on one side of the bodily wall, and first and second ends of the suture are positioned on the opposite side of the bodily wall. The medical device may further include an overtube for delivery of the set of visceral anchors. The overtube has a set of lumens, each lumen receiving a visceral anchor. Portions of the suture located between the visceral anchors extend outside the lumens at a distal end of the overtube. The medical device may also include a set of puncture needles slidably received within the set of lumens, the set of puncture needles receiving the set of visceral anchors therein.
[0006] One embodiment of a visceral anchor, constructed in accordance with the teachings of the present invention, generally comprises a crossbar having a passageway. The crossbar has first and second opposing ends and defines a longitudinal axis. The passageway is located between the opposing ends of the crossbar and slidably receives the suture therein. The passageway has an entrance and an exit through which the suture passes. The entrance and exit are spaced apart a distance greater than 0.001 mm and less than 1.0 mm. By providing the entrance and exit of the passageway in close proximity, the leading and trailing portions of the suture may be kept closer together, and the visceral anchor pulled into closer contact with the tissue, while still retaining the ability to translate the suture relative to the anchor. The passageway is also structured to reduce friction between the suture and crossbar.
[0007] According to more detailed aspects, the passageway may extend parallel to the longitudinal axis of perpendicular to the longitudinal axis. Preferably, the crossbar is constructed of a cannula having a tubular wall defining a lumen. A first opening in the wall defines the entrance and a second opening in the wall defines the exit. The first opening may take the form a first longitudinal slot formed in the first end of the cannula and the second opening is likewise a second longitudinal slot formed in the second end of the cannula. The tubular wall includes a strip portion extending between the first and second slots. In other embodiments, the visceral anchor further comprises a loop, wherein the passageway is defined between the loop and the crossbar. In some embodiments, the loop is formed by a wire connected to the crossbar and projecting outwardly therefrom. When the crossbar is constructed of a cannula having a tubular wall defining a lumen, the tubular wall defines first and second openings and a first end of the wire is passed through the first opening and a second end of the wire is passed through the second opening. The first and second ends of the wire are secured within the lumen of the cannula. In other embodiments, the loop is formed by a rod connected to the crossbar. When the crossbar is constructed of a cannula, the rod is secured within the lumen of the cannula. The tubular wall will define an opening in communication with the lumen to provide access to the rod. The rod may extend parallel with the longitudinal axis or perpendicular to the longitudinal axis.
[0008] According to another aspect of the .present invention, a method for closing a perforation in a bodily wall is provided in accordance with the teachings of the present invention. - The method utilizes a set of visceral anchors connected to a suture as previously described. Each visceral anchor is passed through the bodily wall adjacent the periphery of the perforation. Each visceral anchor is on a distal side of the bodily wall, while the ends of the suture on a proximal side of the bodily wall. The ends of the suture are tensioned to reduce the distance between the visceral anchors and compress the bodily wall around the perforation. The ends of the suture are secured to maintain the compression of the bodily wall and close the perforation.
[0009] According to more detailed aspects, the passing step includes positioning the set of visceral anchors around the perforation to permit closing of the perforation in a purse-string fashion. The passing step preferably includes positioning the set of visceral anchors sequentially around the perforation in a semi- annular or annular shape. Alternatively, the passing step includes positioning the set of visceral anchors sequentially in opposite sides of the perforation. The tensioning steps preferably include independently tensioning the ends of the suture.
BRIEF DESCRIPTION OF THE DRAWINGS
[0010] The accompanying drawings incorporated in and forming a part of the specification illustrate several aspects of the present invention, and together with the description serve to explain the principles of the invention. In the drawings: [0011] FIG. 1 is a front view of a visceral anchor constructed in accordance with the teachings of the present invention;
[0012] FIG. 2 is a top view of the visceral anchor depicted in FIG. 1 ;
[0013] FIG. 3 is a cross-sectional view taken about the line 3-3 in FIG. 1 ;
[0014] FIG. 4 is a plan view schematically depicting a medical device constructed in accordance with the teachings of the present invention; [0015] FIG. 5 is a cross-sectional view of the medical device depicted in FIG.
4;
[0016] FIG. 6 is a schematic view of the medical device similar to FIG. 4 but showing the medical device closing a perforation;
[0017] FIG. 7 is a cross-sectional view of the medical device as depicted in
FIG. 6;
[0018] FIG. 8 is a perspective view, partially cutaway, depicting an overtube for deploying the medical device depicted in FIG. 4;
[0019] FIG. 9 is a perspective view of an alternate embodiment of a visceral anchor constructed in accordance with the teachings of the present invention; [0020] FIG. 10 is a side view of the visceral anchor depicted in FIG. 9;
[0021] FIG. 11 is a plan view of another alternate embodiment of a visceral anchor constructed in accordance with the teachings of the present invention; [0022] FIG. 12 is a cross-sectional view of the visceral anchor depicted in
FIG. 11 ;
[0023] FIG. 13 is a plan view of another alternate embodiment of a visceral anchor constructed in accordance with the teachings of the present invention; [0024] FIG. 14 is a side view of the visceral anchor depicted in FIG. 13; and [0025] FIG. 15 is a side view of the visceral anchor depicted in FIG. 13.
DETAILED DESCRIPTION OF THE INVENTION
[0026] Turning now to the figures, FIGS. 1-3 depict a visceral anchor 20 constructed in accordance with the teachings of the present invention. The anchor 20 is utilized to connect a suture 22 to tissue for closing a perforation 10 in a bodily wall 12 (FIGS. 4 and 5). The anchor 20 generally includes a crossbar 24 having opposing ends 26 and 28. The crossbar 24 is preferably elongated, but may take any form suitable for connecting the suture 22 to the bodily wall 12. A wire 30 connected to the crossbar 24 to form a loop defining a passageway 32 between the wire 30 and crossbar 24. As best seen in FIG. 3, the crossbar 24 is constructed of a cannula having a tubular wall 34 defining a lumen 36. First and second apertures 38, 40 are formed in the tubular wall 34, and the wire 30 passes through the apertures 38, 40. The ends of wire 30 are secured within the lumen 36 of the cannula by welds 44. It will be recognized by those skilled in the art that the wire 30 may be secured to the crossbar 24 using any now known or hereinafter developed attachment means, including mechanical fasteners, adhesives or various welding or soldering techniques.
[0027] Notably,' the passageway 32 has an entrance 46 and an exit 48 through which the suture 22 passes. The entrance and exit are spaced apart a very short distance so that the leading and trailing portions of the suture 22 may remain in close proximity, allowing the crossbar 24 to be pulled extremely close to the bodily wall 12 and ensuring good compression of the tissue and closure of the perforation 10. Preferably, the entrance and exit are spaced apart a distance less than an outer diameter of the crossbar 24, and more preferably a distance greater than 0.001 mm. and less than 1.0 mm. In this embodiment, the distance is defined by a diameter of the wire 30, and hence the wire 30 having a size in this range is selected for construction of the anchor 20. It will also be seen that the wire 30 results in limited friction between the wire 30 and suture 22, ensuring reliable operation for purse- string type closure of the perforation 10. The wire 30 may also be coating with a hydrophilic coating or other material which aids in the reduction of friction. [0028] Turning now to FIGS. 4-7, the visceral anchors 20 are preferably deployed as a set of anchors 20a, 20b, 2Oc1 2Od linked together by a single suture 22, all of which collectively forms a medical device 50 for closing the perforation 10 in the bodily wall 12. The suture 22 is slidably connected to each of the visceral anchors 20a, 20b, 20c, and 20d, leaving two free ends 52, 54 of the suture 22 which may be independently tensioned to close the perforation 10. As best seen in FIG. 5, the visceral anchors (20b and 20c depicted) are positioned on a distal side of the bodily wall 12, while the majority of suture 22 is positioned on a proximal side of the bodily wall 12, including the suture ends 52, 54. Accordingly, it will be recognized that the medical device 50 operates in a purse-string fashion to close the perforation 10 in the bodily wall, as will be described in more detail below. [0029] A method of closing the perforation 10, in accordance with the teachings present invention, includes passing each visceral anchor 20a, 20b, 20c, and 2Od through the bodily wall 12 adjacent the periphery of the perforation 10, as shown in FIG. 4. Preferably, the anchors are sequentially positioned around the perforation 10 in a semi-annular or annular shape as shown. The ends 52, 54 of the suture are then tensioned to reduce the distance between the visceral anchors 20a, 20b, 20c, 2Od and compress the bodily wall 12 around the perforation 10, as depicted in FIGS. 6 and 7. As best seen in FIG. 7, the ends 52, 54 of the suture 22 are secured to maintain the compression of the bodily wall 10, such as through the use of a suture lock 56. Exemplary suture locks are disclosed in U.S. Patent Application Nos. 60/941 ,086 and 60/956,575, the disclosures of which are incorporated herein by reference in their entirety. It will be recognized that any now known or future developed method for securing the ends 52, 54 of the suture 22 may be employed, such as knotting, tying, clamps, rivets and the like. [0030] One preferred delivery mechanism optionally forming a portion of the medical device 50 includes an overtube 60 having a set of lumens 61 , 62, 63, 64, i.e., one lumen for each visceral anchor 20 that is desired to be deployed. Each lumen 61 , 62, 63, 64 extends through a distal end 65 of the overtube 60 and is sized to receive a puncture needled 58 therein. A distal end of the puncture needle 58 receives a visceral anchor 20, and the leading and trailing portions of the suture 22 project distally from each anchor 20. The interconnecting portions of the suture 22 (i.e. between each anchor 20) extend outside of the overtube 60 and along its distal end 65. The free ends 54, 56 of the suture 22 extend proximally along the interior of the overtube 60 (and hence proximally through the bodily lumen) and outside of the body.
[0031] The overtube 60 has an inner diameter D that is preferably sized to be about the same size or greater than the largest dimension of the perforation 10 in the bodily wall 12. Accordingly, it will be recognized that the overtube 60 may be positioned against the bodily wall 12 in a location that covers the perforation 10. Each of the puncture needles 58 may be translated distally and passed through the bodily wall 12. A plunger (not shown) is used to expel the visceral anchors 20 from the puncture needles 58 on the distal side of the bodily wall 12. The puncturing needles 58 are then retracted, as is the overtube 60 to leave the crossbars 24 on the distal side of the bodily wall 12, while the suture 22 and its free ends 54,56 remain on the proximal'side of the bodily wall12.
[0032] It will be recognized that through use of the overtube 60, the entire set of visceral anchors may be simultaneously, deployed, or alternatively may be deployed in various combinations, "such as in pairs or individually, and in various sequences as need or desired. It will.also be recognized that placement of the set of anchors 20 may be aided by fluoroscopy, ultrasound or visually through the use of medical instruments having imaging capabilities such as an endoscope that is passed through the lumen of the overtube 60. The overtube is preferably constructed of a . plastic such as polytetrafluorethylene "(PTFE), expanded polytetrafluorethylene (EPTFE), polyethylene ether ketone (PEEK), polyvinylchloride (PVC), polycarbonate (PC), polyamide including nylon, polyimide, polyurethane, polyethylene - (high, medium or low density), and elastomers such as Santoprene(TM), including multi-layer or single layer constructions with or without reinforcement wires, coils or filaments.
[0033] Turning now to FIGS. 9-14, these figures depict various alternate embodiments of visceral anchors 120, 220, 320 that are constructed in accordance with the teachings of the present invention. In FIGS. 9 and 10, the visceral anchor 120 is again constructed of a crossbar 124 having opposing ends 126, 128 and defining a longitudinal axis. The crossbar 124 is constructed of a cannula having a tubular wall 134 defining an interior lumen 136. In this embodiment, a first slot 140 is formed at the first end 126 of the cannula, and a second slot 142 is formed at the second end 128 of the cannula. The slots 140, 142 extend longitudinally and leave a centrally located strip portion 138 of the cannula. The strip portion 138, in combination with the tubular wall 134, defines a passageway 132 therebetween for receiving a suture 22. The distance between the entrance and exit of the passageway 132 is defined by the length of the strip portion 138. [0034] It will be recognized that the length of strip portion 138 may be sized larger than 1.0 mm, although it may also be smaller. Regardless of the size of the passageway (i.e. between entrance and exit) the passageway is preferably structured to reduce friction between the crossbar and suture, and ensure reliable translation of the anchor relative to the suture. This may be accomplished by eliminating sharp edges, and/or utilizing a hydrophilic coating or other low-friction materials.
[0035] In FIGS. 11 and 12, the visceral anchor 220 includes a crossbar 224 having opposing ends 226, 228 and defining a longitudinal axis. The crossbar 224 is constructed of a cannula having a tubular wall 234 defining an interior lumen 236. In this embodiment, a rod 230 is fitted inside the interior lumen 236. The rod 230 extends parallel to the longitudinal axis and is secured to the ends 226, 228 of the crossbar 224, such as by welds 244. Again, any now known or hereinafter developed connection means may be employed for the rod 230, such as those previously described for the wire 30. An opening 238 is formed in the tubular wall 234 of the crossbar 224 to provide access to the lumen 236 and the rod 230. It will therefore be seen that a passageway 232 is formed by the portion of the lumen 236 located between the rod 230 and tubular wall 234. Here, the distance between the entrance and exit of the passageway 232 is defined by a diameter or width of the rod 230.
[0036] With reference to FIGS. 13 and 14, yet another embodiment of a visceral anchor 320 includes a crossbar 324 having opposing ends 326, 328 and defining a longitudinal axis. The crossbar 324 is constructed from a cannula having a tubular wall 234 defining a lumen 336. Like the previous embodiment, a rod 330 is again positioned within the lumen 336, and an opening 338 in the tubular wall 334 provides access to, the loop and rod 330. However, in this embodiment, the rod 330 is disposed generally perpendicular to the longitudinal axis and is connected to the tubular wall 334, such as by welds 344. Similar to the prior embodiment, a passageway 332 is formed by the portion of the lumen 336 located between the rod 330 and tubular wall 334. The distance between the entrance and exit of the passageway 332 is defined by the diameter or width of the rod 330. [0037] In the previous embodiments a separately formed rod 230, 330 has been depicted as attached to the crossbar 224, 324. However, it will be recognized that the rods or any other loop structures (passageway forming structures) may be integrally and/or unitarily formed with the crossbar, such as by metal injection molding, casting and the like, as well as by material removal techniques such as laser-cutting, blasting, grinding and the like.
[0038] It will also be recognized by those skilled in the art that not only may numerous types of visceral anchors be employed, but the anchors may also be passed through the bodily wall 1-2 and orientated relative to one another in numerous ways. For example, in FIG. 15 the set of visceral anchors 20a, 20b, 20c, 2Od have been placed on opposing sides of a generally linear perforation 10. More specifically, the visceral anchors 20a, 20b, 20c, 2Od have been sequentially positioned on opposite sides of the perforation 10 in a zig-zag configuration. It will be recognized that while semi-annular or zig-zag shapes have been depicted in FIGS. 4 and 15, any number of visceral anchors 20 may be employed, they may be placed in any order and in virtually any configuration. For example, the anchors may criss-cross back and forth and over each other and overlap.
[0039] Notably, the ability of each anchor 20 within a set of anchors to slide relative to "the suture 22 permits the anchors 20 to be spaced apart any desired distance, providing increased flexibility in their orientation. Likewise, both ends 52, 54 of the suture 22 may be independently adjusted or simultaneously adjusted to draw the anchors 20 closer together and close the perforation through compression of the tissue. The ability to pass sutures completely through the bodily wall 12 while retaining a purse-string type" closure improves the compression that may be induced on the bodily wall 12 toward the perforation 10 to ensure a secure and tight closure. [0040] The foregoing description of various embodiments of the invention has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Numerous modifications or variations are possible in light of the above teachings. The embodiments discussed were chosen and described to provide the best illustration of the principles of the invention and its practical application to thereby enable one of ordinary skill in the art to utilize the invention in various embodiments and with various modifications as are suited to the particular use contemplated. All such modifications and variations are within the scope of the invention as determined by the appended claims when interpreted in accordance with the breadth to which they are fairly, legally, and equitably entitled.

Claims

1. A medical device for closing a perforation in a bodily wall, the medical device comprising: a suture having opposing first and second ends; a set of visceral anchors, each visceral anchor including a cross bar having opposing ends, the suture being slidably attached to each of the crossbars; the first and second ends of the suture capable of being independently tensioned for translating the suture relative to each of the visceral anchors and closing the perforation.
2. The medical device of claim 1 , wherein the tensioning of the suture reduces the distance between the visceral anchors for closing the perforation in a purse-string fashion.
3. The medical device of claim 1 , wherein each visceral anchor is positioned on one side of the bodily wall, and wherein the first and second ends of the suture are positioned on the opposite side of the bodily wall.
4. The medical device of claim 1 , wherein each visceral anchor includes a passageway between the opposing ends of the crossbar the passageway having an entrance and an exit through which the suture passes, the entrance and exit being spaced apart a distance less than an outer diameter of the crossbar greater than 0.001 mm and less than 1.0 mm.
5. The medical device of claim 1 , further comprising an overtube for delivery of the set of visceral anchors, the overtube having a set of lumens, each lumen receiving a visceral anchor, portions of the suture located between the visceral anchors extending outside the lumens at a distal end of the overtube.
6. The medical device of claim 5, further comprising a set of puncture needles slidably received with the set of lumens, the set of puncture needles receiving the set of visceral anchors therein.
7. A visceral anchor for connecting a suture to tissue, the visceral anchor comprising: a cross bar having first and second opposing ends, the cross bar defining a longitudinal axis; and a passageway located between the opposing -ends of the cross bar, the passageway slidably receiving the suture therein; the passageway having an entrance and an exit through which the suture passes, the entrance and exit being spaced apart a distance less than an outer diameter of the crossbar greater than 0.001 mm and less than 1.0 mm.
8. The visceral anchor of -claim 7, wherein the entrance and exit are spaced apart a distance greater than .001mm and less than 1mm.
9. The visceral anchor of claim 7, wherein the passageway extends parallel to the longitudinal axis.
10. The visceral anchor of claim 7, wherein the cross bar is constructed of a cannula having a tubular wall defining a lumen, a first opening in the wall defining the entrance, a second opening in the wall defining the exit.
11. The visceral anchor of claim 10, wherein the first opening is a first longitudinal slot formed in the first end of the cannula, and the second opening is a second longitudinal slot formed in the second end of the cannula, and wherein the tubular wall includes a strip portion extending between the first and second slots.
12. The visceral anchor of claim 7, further comprising a wire connected to the crossbar, the passageway being defined between the wire and the cross bar.
13. The visceral anchor of claim 11 , wherein the cross bar is constructed of a cannula having a tubular wall defining a lumen, the tubular wall defining first and second openings, a first end of the wire passing through a first opening, a second end of the wire passing through the second opening.
14. The visceral anchor of claim 13, wherein the first and second ends of the wire are secured within the lumen of the cannula.
15. The visceral anchor of claim 13, further comprising a rod connected to the cross bar, the passageway being defined between the rod and the crossbar.
16. The visceral anchor of claim 15, wherein the cross bar is constructed of a cannula having a tubular wall defining a lumen, and wherein the rod is secured within the lumen of the cannula.
17. The visceral anchor of claim 16, wherein the tubular wall defines an opening in communication with the lumen, the opening providing access to the rod.
18. The visceral anchor of claim 16, wherein the rod extends parallel with the longitudinal axis.
19. The visceral anchor of claim 16, wherein the rod extends perpendicular to the longitudinal axis.
20. A method for closing a perforation in a bodily wall using a set of visceral anchors connected to a suture, each visceral anchor including a cross bar slidably attached to the suture, the method comprising the steps of: passing each visceral anchor through the bodily wall adjacent the periphery of the perforation, each visceral anchor being on a distal side of the bodily wall, the ends of the suture being on a proximal side of the bodily wall; tensioning the ends of the suture to reduce the distance between the visceral anchors and compress the bodily wall around the perforation; and securing the ends of the suture to maintain the compression of the bodily wall and close the perforation.
21. The method of claim 20, wherein the passing step includes positioning the set of visceral anchors around the perforation to permit closing of the perforation in a purse-string fashion.
22. The method of claim 20, wherein the passing step includes positioning the set of visceral anchors sequentially around the perforation in a semi-annular or annular shape.
23. The method of claim 20, wherein the passing step includes positioning the set of visceral anchors sequentially on opposite sides of the perforation.
24. The method of claim 20, wherein the tensioning step includes independently tensioning the ends of the suture.
PCT/US2007/085769 2006-11-30 2007-11-28 Visceral anchors for purse-string closure of perforations WO2008067384A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2671030A CA2671030C (en) 2006-11-30 2007-11-28 Visceral anchors for purse-string closure of perforations
EP07868914A EP2094167B1 (en) 2006-11-30 2007-11-28 Visceral anchors for purse-string closure of perforations
JP2009539460A JP5270565B2 (en) 2006-11-30 2007-11-28 Visceral Anchor for Closing Perforated Drawstring Suture
AT07868914T ATE514382T1 (en) 2006-11-30 2007-11-28 FABRIC ANCHOR FOR SEAM CLOSURE OF PERFORATIONS
AU2007325204A AU2007325204B2 (en) 2006-11-30 2007-11-28 Visceral anchors for purse-string closure of perforations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87202306P 2006-11-30 2006-11-30
US60/872,023 2006-11-30

Publications (2)

Publication Number Publication Date
WO2008067384A2 true WO2008067384A2 (en) 2008-06-05
WO2008067384A3 WO2008067384A3 (en) 2008-09-25

Family

ID=39381996

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/085769 WO2008067384A2 (en) 2006-11-30 2007-11-28 Visceral anchors for purse-string closure of perforations

Country Status (7)

Country Link
US (1) US8551139B2 (en)
EP (1) EP2094167B1 (en)
JP (1) JP5270565B2 (en)
AT (1) ATE514382T1 (en)
AU (1) AU2007325204B2 (en)
CA (1) CA2671030C (en)
WO (1) WO2008067384A2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010065728A1 (en) * 2008-12-05 2010-06-10 Wilson-Cook Medical, Inc. Tissue anchors for purse-string closure of perforations
JP2012504482A (en) * 2008-10-06 2012-02-23 ウィルソン−クック・メディカル・インコーポレーテッド End cap for secure deployment of tissue anchors
JP2013517108A (en) * 2010-01-20 2013-05-16 ニュー ホープ ベンチャーズ，リミティド パートナーシップ Tissue occlusion device and method
US8647368B2 (en) 2009-04-03 2014-02-11 Cook Medical Technologies Llc Tissue anchors and medical devices for rapid deployment of tissue anchors
US9980708B2 (en) 2010-01-20 2018-05-29 Micro Interventional Devices, Inc. Tissue closure device and method
US10058314B2 (en) 2010-01-20 2018-08-28 Micro Interventional Devices, Inc. Tissue closure device and method
US10743854B2 (en) 2010-01-20 2020-08-18 Micro Interventional Devices, Inc. Tissue closure device and method
US10959840B2 (en) 2010-01-20 2021-03-30 Micro Interventional Devices, Inc. Systems and methods for affixing a prosthesis to tissue

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8840645B2 (en) * 2004-11-05 2014-09-23 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8303604B2 (en) 2004-11-05 2012-11-06 Biomet Sports Medicine, Llc Soft tissue repair device and method
US8361113B2 (en) 2006-02-03 2013-01-29 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8298262B2 (en) 2006-02-03 2012-10-30 Biomet Sports Medicine, Llc Method for tissue fixation
US7749250B2 (en) 2006-02-03 2010-07-06 Biomet Sports Medicine, Llc Soft tissue repair assembly and associated method
US7909851B2 (en) 2006-02-03 2011-03-22 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US7658751B2 (en) 2006-09-29 2010-02-09 Biomet Sports Medicine, Llc Method for implanting soft tissue
US9801708B2 (en) 2004-11-05 2017-10-31 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8137382B2 (en) 2004-11-05 2012-03-20 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8088130B2 (en) 2006-02-03 2012-01-03 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9017381B2 (en) 2007-04-10 2015-04-28 Biomet Sports Medicine, Llc Adjustable knotless loops
US8128658B2 (en) 2004-11-05 2012-03-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US7905904B2 (en) 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US8118836B2 (en) 2004-11-05 2012-02-21 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8998949B2 (en) 2004-11-09 2015-04-07 Biomet Sports Medicine, Llc Soft tissue conduit device
US8652171B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US8597327B2 (en) 2006-02-03 2013-12-03 Biomet Manufacturing, Llc Method and apparatus for sternal closure
US8251998B2 (en) 2006-08-16 2012-08-28 Biomet Sports Medicine, Llc Chondral defect repair
US9468433B2 (en) 2006-02-03 2016-10-18 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8562647B2 (en) * 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for securing soft tissue to bone
US8652172B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Flexible anchors for tissue fixation
US11311287B2 (en) 2006-02-03 2022-04-26 Biomet Sports Medicine, Llc Method for tissue fixation
US9538998B2 (en) 2006-02-03 2017-01-10 Biomet Sports Medicine, Llc Method and apparatus for fracture fixation
US9149267B2 (en) 2006-02-03 2015-10-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9078644B2 (en) 2006-09-29 2015-07-14 Biomet Sports Medicine, Llc Fracture fixation device
US9271713B2 (en) 2006-02-03 2016-03-01 Biomet Sports Medicine, Llc Method and apparatus for tensioning a suture
US11259792B2 (en) 2006-02-03 2022-03-01 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8771352B2 (en) 2011-05-17 2014-07-08 Biomet Sports Medicine, Llc Method and apparatus for tibial fixation of an ACL graft
US8506597B2 (en) 2011-10-25 2013-08-13 Biomet Sports Medicine, Llc Method and apparatus for interosseous membrane reconstruction
US10517587B2 (en) 2006-02-03 2019-12-31 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8574235B2 (en) 2006-02-03 2013-11-05 Biomet Sports Medicine, Llc Method for trochanteric reattachment
US8968364B2 (en) 2006-02-03 2015-03-03 Biomet Sports Medicine, Llc Method and apparatus for fixation of an ACL graft
US8801783B2 (en) 2006-09-29 2014-08-12 Biomet Sports Medicine, Llc Prosthetic ligament system for knee joint
US11259794B2 (en) 2006-09-29 2022-03-01 Biomet Sports Medicine, Llc Method for implanting soft tissue
US9918826B2 (en) 2006-09-29 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
US8672969B2 (en) 2006-09-29 2014-03-18 Biomet Sports Medicine, Llc Fracture fixation device
US8500818B2 (en) 2006-09-29 2013-08-06 Biomet Manufacturing, Llc Knee prosthesis assembly with ligament link
EP2205161B1 (en) 2007-09-25 2016-11-30 Cook Medical Technologies LLC Medical devices, systems, and methods for using tissue anchors
US20110295181A1 (en) 2008-03-05 2011-12-01 Hemosphere, Inc. Implantable and removable customizable body conduit
US8343227B2 (en) 2009-05-28 2013-01-01 Biomet Manufacturing Corp. Knee prosthesis assembly with ligament link
US12096928B2 (en) 2009-05-29 2024-09-24 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9220523B2 (en) 2009-09-14 2015-12-29 The Spectranetics Corporation Snaring systems and methods
EP2490601B1 (en) 2009-10-19 2015-07-08 Cook Medical Technologies LLC Balloon-tipped endoscopic system with inverted sleeve
EP2694667B1 (en) 2011-04-08 2016-12-07 Baystate Medical Center, Inc. Methods, compositions and kits for assaying mitochondrial function
US8777965B2 (en) * 2011-04-15 2014-07-15 Usgi Medical, Inc. Devices and methods for laparoscopic hernia repair
US9357991B2 (en) 2011-11-03 2016-06-07 Biomet Sports Medicine, Llc Method and apparatus for stitching tendons
US9314241B2 (en) 2011-11-10 2016-04-19 Biomet Sports Medicine, Llc Apparatus for coupling soft tissue to a bone
US9370350B2 (en) 2011-11-10 2016-06-21 Biomet Sports Medicine, Llc Apparatus for coupling soft tissue to a bone
US9381013B2 (en) 2011-11-10 2016-07-05 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9445803B2 (en) * 2011-11-23 2016-09-20 Howmedica Osteonics Corp. Filamentary suture anchor
US9808242B2 (en) 2012-04-06 2017-11-07 Howmedica Osteonics Corp. Knotless filament anchor for soft tissue repair
US9757119B2 (en) 2013-03-08 2017-09-12 Biomet Sports Medicine, Llc Visual aid for identifying suture limbs arthroscopically
US9918827B2 (en) 2013-03-14 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
WO2014176270A1 (en) 2013-04-22 2014-10-30 Pivot Medical, Inc. Method and apparatus for attaching tissue to bone
US10136886B2 (en) 2013-12-20 2018-11-27 Biomet Sports Medicine, Llc Knotless soft tissue devices and techniques
US9615822B2 (en) 2014-05-30 2017-04-11 Biomet Sports Medicine, Llc Insertion tools and method for soft anchor
US9700291B2 (en) 2014-06-03 2017-07-11 Biomet Sports Medicine, Llc Capsule retractor
WO2015193881A1 (en) 2014-06-15 2015-12-23 Anchora Medical Ltd. Apparatus and method for suturing a tissue
US9566055B2 (en) 2014-06-23 2017-02-14 Kyphon SÀRL Cannula with deployable anchor wire and methods of use
US10039543B2 (en) 2014-08-22 2018-08-07 Biomet Sports Medicine, Llc Non-sliding soft anchor
US10576274B2 (en) 2014-12-30 2020-03-03 Spectranetics Llc Expanding coil coupling for lead extension and extraction
US9731113B2 (en) 2014-12-30 2017-08-15 The Spectranetics Corporation Collapsing coil coupling for lead extension and extraction
US9884184B2 (en) 2014-12-30 2018-02-06 The Spectranetics Corporation Wire hook coupling for lead extension and extraction
US10105533B2 (en) 2014-12-30 2018-10-23 The Spectranetics Corporation Multi-loop coupling for lead extension and extraction
US9955980B2 (en) 2015-02-24 2018-05-01 Biomet Sports Medicine, Llc Anatomic soft tissue repair
US9974534B2 (en) 2015-03-31 2018-05-22 Biomet Sports Medicine, Llc Suture anchor with soft anchor of electrospun fibers
US10639028B2 (en) * 2015-10-29 2020-05-05 Apollo Endosurgery Us, Inc. Endoscopic suture loop anchors and methods
CN110461247B (en) 2016-11-13 2024-02-20 安奇拉医疗有限公司 Minimally invasive tissue suturing device
WO2018132573A1 (en) 2017-01-12 2018-07-19 Merit Medical Systems, Inc. Methods and systems for selection and use of connectors between conduits
EP3592401B1 (en) * 2017-03-06 2024-09-18 Merit Medical Systems, Inc. Vascular access assembly declotting systems and methods
US11179543B2 (en) 2017-07-14 2021-11-23 Merit Medical Systems, Inc. Releasable conduit connectors
EP3655086A4 (en) 2017-07-20 2021-04-07 Merit Medical Systems, Inc. Methods and systems for coupling conduits
WO2019089569A1 (en) 2017-10-31 2019-05-09 Merit Medical Systems, Inc. Subcutaneous vascular assemblies for improving blood flow and related devices and methods
CN109717918B (en) * 2019-03-13 2024-04-26 上海捍宇医疗科技股份有限公司 Apex stitching instrument
US20210275162A1 (en) * 2020-03-05 2021-09-09 Apollo Endosurgery Us, Inc. Surgical fastener deployment system
CN116831654A (en) * 2023-07-07 2023-10-03 陕西福泰医疗科技有限公司 Combined traction device, traction stitching device and traction puncture device

Family Cites Families (387)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1521396A (en) 1924-12-30 By mary v
US775985A (en) 1904-03-18 1904-11-29 Harry L Mckain Machine for manufacturing artificial flowers, vines, &c.
US1037864A (en) 1911-04-20 1912-09-10 John C Carlson Surgical-needle holder.
US2199025A (en) 1936-06-08 1940-04-30 Carl E Conn Means and method of closing surgical incisions
US2609155A (en) 1950-06-15 1952-09-02 Adolph Spreckles Fishing rod wrapping device
US2880728A (en) 1958-02-03 1959-04-07 Clyde S Rights Ligature inserter
US3299883A (en) 1963-11-08 1967-01-24 Engelhard Hanovia Inc Gynecologic instrument
US3470875A (en) 1966-10-06 1969-10-07 Alfred A Johnson Surgical clamping and suturing instrument
US3556079A (en) 1967-05-16 1971-01-19 Haruo Omizo Method of puncturing a medical instrument under guidance of ultrasound
US3513848A (en) 1967-12-11 1970-05-26 Ultrasonic Systems Ultrasonic suturing
US3664345A (en) 1970-07-06 1972-05-23 Clyde Harwell Dabbs Surgical buttons
US3710400A (en) 1971-08-30 1973-01-16 C Sparks Graft member grown in a living body
US3709214A (en) 1971-10-27 1973-01-09 J Robertson Gas obturating method
US3856016A (en) 1972-11-03 1974-12-24 H Davis Method for mechanically applying an occlusion clip to an anatomical tubular structure
US3954108A (en) 1972-11-03 1976-05-04 Davis Hugh J Occlusion clip and instrument for applying same
US3870048A (en) 1973-07-30 1975-03-11 In Bae Yoon Device for sterilizing the human female or male by ligation
US3989049A (en) 1973-07-30 1976-11-02 In Bae Yoon Method of applying an elastic ring to an anatomical tubular structure
US3967625A (en) 1973-07-30 1976-07-06 In Bae Yoon Device for sterilizing the human female or male by ligation
US3911923A (en) 1973-07-30 1975-10-14 In Bae Yoon Occlusion ring and method and device for its application
US4022208A (en) 1974-07-25 1977-05-10 Valtchev Konstantin L Gynecologic instrument
US4374523A (en) 1974-10-29 1983-02-22 Yoon In B Occlusion ring applicator
US4103680A (en) 1975-08-15 1978-08-01 In Bae Yoon Multiple occlusion ring applicator and method
US4085743A (en) 1976-03-02 1978-04-25 In Bae Yoon Multiple occlusion ring applicator and method
JPS5835219Y2 (en) * 1978-06-01 1983-08-08 オリンパス光学工業株式会社 Body cavity tissue suturing device
US4235238A (en) 1978-05-11 1980-11-25 Olympus Optical Co., Ltd. Apparatus for suturing coeliac tissues
US4236470A (en) 1979-01-17 1980-12-02 Stenson Thomas K Portable stitching device
US4539716A (en) 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4448194A (en) 1982-02-03 1984-05-15 Ethicon, Inc. Full stroke compelling mechanism for surgical instrument with drum drive
US5417691A (en) 1982-05-20 1995-05-23 Hayhurst; John O. Apparatus and method for manipulating and anchoring tissue
US4823794A (en) * 1982-07-12 1989-04-25 Pierce William S Surgical pledget
US4635638A (en) 1984-02-07 1987-01-13 Galil Advanced Technologies Ltd. Power-driven gripping tool particularly useful as a suturing device
US4798606A (en) 1985-02-26 1989-01-17 Corvita Corporation Reinforcing structure for cardiovascular graft
US4669473A (en) * 1985-09-06 1987-06-02 Acufex Microsurgical, Inc. Surgical fastener
US4738740A (en) 1985-11-21 1988-04-19 Corvita Corporation Method of forming implantable vascular grafts
US5123914A (en) 1986-05-19 1992-06-23 Cook Incorporated Visceral anchor for visceral wall mobilization
US4749114A (en) 1986-11-10 1988-06-07 United States Surgical Corporation Purse string applicator and method of affixing a purse string
US5478353A (en) 1987-05-14 1995-12-26 Yoon; Inbae Suture tie device system and method for suturing anatomical tissue proximate an opening
US4773420A (en) 1987-06-22 1988-09-27 U.S. Surgical Corporation Purse string applicator
US4821939A (en) 1987-09-02 1989-04-18 United States Surgical Corporation Staple cartridge and an anvilless surgical stapler
US4918785A (en) * 1987-10-26 1990-04-24 Spinner Ralphael F Mechanical knot for ropes
US4890615B1 (en) 1987-11-05 1993-11-16 Linvatec Corporation Arthroscopic suturing instrument
US5084057A (en) 1989-07-18 1992-01-28 United States Surgical Corporation Apparatus and method for applying surgical clips in laparoscopic or endoscopic procedures
US4927410A (en) 1988-11-18 1990-05-22 University Of South Florida Method for fabricating prosthesis material
US5318221A (en) 1989-05-26 1994-06-07 United States Surgical Corporation Apparatus and method for placing staples in laparoscopic or endoscopic procedures
US5290300A (en) 1989-07-31 1994-03-01 Baxter International Inc. Flexible suture guide and holder
US5059201A (en) 1989-11-03 1991-10-22 Asnis Stanley E Suture threading, stitching and wrapping device for use in open and closed surgical procedures
US5015250A (en) 1990-01-12 1991-05-14 Vance Products Incorporated Medical instrument for driving a suture needle
US5053043A (en) 1990-09-28 1991-10-01 Vance Products Incorporated Suture guide and method of placing sutures through a severed duct
US5141515A (en) 1990-10-11 1992-08-25 Eberbach Mark A Apparatus and methods for repairing hernias
US5203787A (en) 1990-11-19 1993-04-20 Biomet, Inc. Suture retaining arrangement
US5316543A (en) 1990-11-27 1994-05-31 Cook Incorporated Medical apparatus and methods for treating sliding hiatal hernias
US5366458A (en) 1990-12-13 1994-11-22 United States Surgical Corporation Latchless surgical clip
US5366480A (en) 1990-12-24 1994-11-22 American Cyanamid Company Synthetic elastomeric buttressing pledget
US5310407A (en) 1991-06-17 1994-05-10 Datascope Investment Corp. Laparoscopic hemostat delivery system and method for using said system
EP0595892B1 (en) 1991-07-23 1995-12-20 Forschungszentrum Karlsruhe GmbH Surgical stitching instrument
CA2075141C (en) 1991-10-17 1998-06-30 Donald A. Morin Anvil for surgical staplers
DE4137218C1 (en) 1991-11-13 1993-02-11 Heidmueller, Harald, 5000 Koeln, De
DK168419B1 (en) 1991-11-25 1994-03-28 Cook Inc A Cook Group Company Abdominal wall support device and apparatus for insertion thereof
US5258000A (en) 1991-11-25 1993-11-02 Cook Incorporated Tissue aperture repair device
US5333624A (en) 1992-02-24 1994-08-02 United States Surgical Corporation Surgical attaching apparatus
US5417203A (en) 1992-04-23 1995-05-23 United States Surgical Corporation Articulating endoscopic surgical apparatus
US5368601A (en) 1992-04-30 1994-11-29 Lasersurge, Inc. Trocar wound closure device
US5484451A (en) 1992-05-08 1996-01-16 Ethicon, Inc. Endoscopic surgical instrument and staples for applying purse string sutures
US5254126A (en) 1992-06-24 1993-10-19 Ethicon, Inc. Endoscopic suture punch
US5458131A (en) 1992-08-25 1995-10-17 Wilk; Peter J. Method for use in intra-abdominal surgery
US5297536A (en) 1992-08-25 1994-03-29 Wilk Peter J Method for use in intra-abdominal surgery
US5364408A (en) 1992-09-04 1994-11-15 Laurus Medical Corporation Endoscopic suture system
US5578044A (en) 1992-09-04 1996-11-26 Laurus Medical Corporation Endoscopic suture system
US5540704A (en) 1992-09-04 1996-07-30 Laurus Medical Corporation Endoscopic suture system
CA2106127A1 (en) 1992-09-23 1994-03-24 Peter W.J. Hinchliffe Instrument for closing trocar puncture wounds
US5281237A (en) 1992-09-25 1994-01-25 Gimpelson Richard J Surgical stitching device and method of use
US5368599A (en) 1992-10-08 1994-11-29 United States Surgical Corporation Surgical fastening apparatus with suture array
US5222508A (en) 1992-10-09 1993-06-29 Osvaldo Contarini Method for suturing punctures of the human body
US5304184A (en) 1992-10-19 1994-04-19 Indiana University Foundation Apparatus and method for positive closure of an internal tissue membrane opening
IL103737A (en) 1992-11-13 1997-02-18 Technion Res & Dev Foundation Stapler device particularly useful in medical suturing
US5693060A (en) 1992-11-17 1997-12-02 Smith & Nephew, Inc. Suture securing device and method
US5643317A (en) 1992-11-25 1997-07-01 William Cook Europe S.A. Closure prosthesis for transcatheter placement
US6355050B1 (en) 1992-12-10 2002-03-12 Abbott Laboratories Device and method for suturing tissue
US5417699A (en) 1992-12-10 1995-05-23 Perclose Incorporated Device and method for the percutaneous suturing of a vascular puncture site
US6036699A (en) 1992-12-10 2000-03-14 Perclose, Inc. Device and method for suturing tissue
US5336229A (en) 1993-02-09 1994-08-09 Laparomed Corporation Dual ligating and dividing apparatus
US5320630A (en) 1993-02-23 1994-06-14 Munir Ahmed Endoscopic ligating instrument for applying elastic bands
US5374275A (en) 1993-03-25 1994-12-20 Synvasive Technology, Inc. Surgical suturing device and method of use
US5350385A (en) 1993-04-28 1994-09-27 Christy William J Surgical stab wound closure device and method
US5464426A (en) * 1993-05-14 1995-11-07 Bonutti; Peter M. Method of closing discontinuity in tissue
US5549630A (en) * 1993-05-14 1996-08-27 Bonutti; Peter M. Method and apparatus for anchoring a suture
US5403348A (en) 1993-05-14 1995-04-04 Bonutti; Peter M. Suture anchor
US5423860A (en) 1993-05-28 1995-06-13 American Cyanamid Company Protective carrier for suture anchor
US5562687A (en) 1993-07-12 1996-10-08 Mitek Surgical Products, Inc. Surgical repair kit and its method of use
US5527321A (en) 1993-07-14 1996-06-18 United States Surgical Corporation Instrument for closing trocar puncture wounds
US5454820A (en) 1993-07-14 1995-10-03 Ethicon, Inc. Method of tying knots using a tube knot applicator
US5391182A (en) 1993-08-03 1995-02-21 Origin Medsystems, Inc. Apparatus and method for closing puncture wounds
US5462561A (en) 1993-08-05 1995-10-31 Voda; Jan K. Suture device
US5405354A (en) 1993-08-06 1995-04-11 Vance Products Inc. Suture driver
CA2124651C (en) 1993-08-20 2004-09-28 David T. Green Apparatus and method for applying and adjusting an anchoring device
US5507754A (en) 1993-08-20 1996-04-16 United States Surgical Corporation Apparatus and method for applying and adjusting an anchoring device
US5470338A (en) 1993-10-08 1995-11-28 United States Surgical Corporation Instrument for closing trocar puncture wounds
US5584835A (en) 1993-10-18 1996-12-17 Greenfield; Jon B. Soft tissue to bone fixation device and method
WO1995011630A1 (en) 1993-10-25 1995-05-04 Children's Medical Center Corporation Retractable suture needle with self-contained driver
US5439469A (en) 1993-11-05 1995-08-08 Advanced Surgical, Inc. Wound closure device
JP3398200B2 (en) 1993-11-24 2003-04-21 テルモ株式会社 Needle holder
US5609597A (en) 1993-12-09 1997-03-11 Lehrer; Theodor Apparatus and method of extracorporeally applying and locking laparoscopic suture and loop ligatures
US5376096A (en) 1993-12-17 1994-12-27 Vance Products Inc. Medical instrument for driving a suture needle
IT1269443B (en) 1994-01-19 1997-04-01 Stefano Nazari VASCULAR PROSTHESIS FOR THE REPLACEMENT OR INTERNAL COATING OF MEDIUM AND LARGE DIAMETER BLOOD VESSELS AND DEVICE FOR ITS APPLICATION WITHOUT INTERRUPTION OF BLOOD FLOW
US5391173A (en) 1994-02-10 1995-02-21 Wilk; Peter J. Laparoscopic suturing technique and associated device
GB9405790D0 (en) 1994-03-23 1994-05-11 Univ London Sewing device
US5486197A (en) 1994-03-24 1996-01-23 Ethicon, Inc. Two-piece suture anchor with barbs
US5562688A (en) 1994-03-25 1996-10-08 Riza; Erol D. Apparatus facilitating suturing in laparoscopic surgery
US5630824A (en) 1994-06-01 1997-05-20 Innovasive Devices, Inc. Suture attachment device
US5573540A (en) 1994-07-18 1996-11-12 Yoon; Inbae Apparatus and method for suturing an opening in anatomical tissue
US5573542A (en) 1994-08-17 1996-11-12 Tahoe Surgical Instruments-Puerto Rico Endoscopic suture placement tool
US5462558A (en) 1994-08-29 1995-10-31 United States Surgical Corporation Suture clip applier
US5464427A (en) 1994-10-04 1995-11-07 Synthes (U.S.A.) Expanding suture anchor
CA2157744C (en) 1994-10-07 2005-08-23 Charles R. Sherts Endoscopic vascular suturing apparatus
US5571090A (en) 1994-10-07 1996-11-05 United States Surgical Corporation Vascular suturing apparatus
US5938668A (en) 1994-10-07 1999-08-17 United States Surgical Surgical suturing apparatus
US5531763A (en) 1994-10-07 1996-07-02 United States Surgical Corporation Suture cinching apparatus
US5643292A (en) 1995-01-10 1997-07-01 Applied Medical Resources Corporation Percutaneous suturing device
US5645552A (en) 1995-01-11 1997-07-08 United States Surgical Corporation Surgical apparatus for suturing body tissue
US5503623A (en) 1995-03-17 1996-04-02 Tilton, Jr.; Eugene B. Instrumentation for laparoscopic insertion and application of sheet like surgical material
US5919184A (en) 1995-03-17 1999-07-06 Tilton, Jr.; Eugene B. Instrumentation for laparoscopic insertion and application of surgical sheet material
US5709694A (en) 1995-03-22 1998-01-20 Human Factors Industrial Design, Inc. Endoscopic intracorporeal suture tying aid
US6086608A (en) 1996-02-22 2000-07-11 Smith & Nephew, Inc. Suture collet
US6132438A (en) 1995-06-07 2000-10-17 Ep Technologies, Inc. Devices for installing stasis reducing means in body tissue
US5690656A (en) 1995-06-27 1997-11-25 Cook Incorporated Method and apparatus for creating abdominal visceral anastomoses
US5700273A (en) 1995-07-14 1997-12-23 C.R. Bard, Inc. Wound closure apparatus and method
US5846253A (en) 1995-07-14 1998-12-08 C. R. Bard, Inc. Wound closure apparatus and method
US5662683A (en) 1995-08-22 1997-09-02 Ortho Helix Limited Open helical organic tissue anchor and method of facilitating healing
AU6858896A (en) 1995-08-24 1997-03-19 Nobles-Lai Engineering, Inc. Method and apparatus for suturing
EP0955894A4 (en) 1995-08-25 2001-02-28 R Thomas Grotz Stabilizer for human joints
US5653717A (en) 1995-08-28 1997-08-05 Urohealth Systems, Inc. Wound closure device
US5707379A (en) 1995-10-20 1998-01-13 Coral Medical Method and apparatus for intracorporeal suturing
US5788625A (en) 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5824010A (en) 1996-05-23 1998-10-20 Mcdonald; Garth R. Suture needle guide
US5810848A (en) * 1996-08-21 1998-09-22 Hayhurst; John O. Suturing system
US5865836A (en) 1996-09-20 1999-02-02 United States Surgical Corporation Needle-suture combination
US5948000A (en) 1996-10-03 1999-09-07 United States Surgical Corporation System for suture anchor placement
US5902228A (en) 1996-10-11 1999-05-11 Cornell Research Foundation, Inc. Method and apparatus for support and tubularization of surgical grafts
US5957937A (en) 1996-11-27 1999-09-28 Yoon; Inbae Suturing instrument with spreadable needle holder mounted for arcuate movement
US5891159A (en) 1997-05-02 1999-04-06 Cardiothoratic Systems, Inc. Automatic purse string suture device
US5908428A (en) 1997-05-27 1999-06-01 United States Surgical Corporation Stitching devices for heart valve replacement surgery
US6077217A (en) 1997-06-25 2000-06-20 Ramus Medical Technologies, Inc. System and method for assembling graft structures
US6071292A (en) * 1997-06-28 2000-06-06 Transvascular, Inc. Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures
DE19731834A1 (en) * 1997-07-24 1999-06-17 Ernst Peter Prof Dr M Strecker Implantation device
US6293952B1 (en) 1997-07-31 2001-09-25 Circon Corporation Medical instrument system for piercing through tissue
US6010525A (en) 1997-08-01 2000-01-04 Peter M. Bonutti Method and apparatus for securing a suture
US6264677B1 (en) * 1997-10-15 2001-07-24 Applied Biological Concepts, Inc. Wedge screw suture anchor
JP3342021B2 (en) 1997-10-17 2002-11-05 サーコン コーポレーション Medical device system that penetrates tissue
US6068648A (en) 1998-01-26 2000-05-30 Orthodyne, Inc. Tissue anchoring system and method
AU3869599A (en) 1998-04-29 1999-11-16 Inbae Yoon Instrument and method of suturing anatomical tissue and tying suture material
US6610026B2 (en) 1998-05-01 2003-08-26 Sub-Q, Inc. Method of hydrating a sponge material for delivery to a body
EP1079740B1 (en) 1998-05-21 2007-08-29 Christopher J. Walshe A tissue anchor system
US6099553A (en) 1998-05-21 2000-08-08 Applied Medical Resources Corporation Suture clinch
US7060084B1 (en) 1998-05-29 2006-06-13 By-Pass, Inc. Vascular closure device
US6030365A (en) 1998-06-10 2000-02-29 Laufer; Michael D. Minimally invasive sterile surgical access device and method
US6200329B1 (en) 1998-08-31 2001-03-13 Smith & Nephew, Inc. Suture collet
US6679851B2 (en) * 1998-09-01 2004-01-20 Senorx, Inc. Tissue accessing and anchoring device and method
DE69920178T2 (en) 1998-12-09 2005-09-22 Cook Inc., Bloomington SUPER-ELASTIC CURVED CAVITY NEEDLE FOR MEDICAL USE
US6110183A (en) 1998-12-22 2000-08-29 Cook Incorporated Suture anchor device
ATE324072T1 (en) 1998-12-30 2006-05-15 Ethicon Inc THREAD SECURING DEVICE
US9295581B2 (en) 1999-01-05 2016-03-29 Second Sight Medical Products, Inc. Medical tack with a variable effective length
US5987707A (en) * 1999-01-05 1999-11-23 Deshon; James Richard Bungee cord shortening device
CA2261488A1 (en) 1999-01-21 2000-07-21 Anthony Paolitto Transabdominal device for performing closed-chest cardiac surgery
US7226467B2 (en) 1999-04-09 2007-06-05 Evalve, Inc. Fixation device delivery catheter, systems and methods of use
US6482178B1 (en) 1999-05-21 2002-11-19 Cook Urological Incorporated Localization device with anchoring barbs
US7416554B2 (en) * 2002-12-11 2008-08-26 Usgi Medical Inc Apparatus and methods for forming and securing gastrointestinal tissue folds
US8574243B2 (en) 1999-06-25 2013-11-05 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US20040122456A1 (en) * 2002-12-11 2004-06-24 Saadat Vahid C. Methods and apparatus for gastric reduction
US7618426B2 (en) * 2002-12-11 2009-11-17 Usgi Medical, Inc. Apparatus and methods for forming gastrointestinal tissue approximations
JP4108882B2 (en) 1999-08-04 2008-06-25 オリンパス株式会社 Endoscope wall fixture
US6231561B1 (en) 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
EP1225948B1 (en) * 1999-09-20 2007-08-08 ev3 Endovascular, Inc. Apparatus for closing a body lumen
US6257163B1 (en) * 1999-10-13 2001-07-10 Kenneth Scott Carpenter Utility tether and apparatus therefore
US6626930B1 (en) * 1999-10-21 2003-09-30 Edwards Lifesciences Corporation Minimally invasive mitral valve repair method and apparatus
AU1464401A (en) 1999-11-05 2001-06-06 Onux Medical, Inc. Apparatus and method for approximating and closing the walls of a hole or puncture in a physiological shell structure
US6503273B1 (en) 1999-11-22 2003-01-07 Cyograft Tissue Engineering, Inc. Tissue engineered blood vessels and methods and apparatus for their manufacture
US6689062B1 (en) 1999-11-23 2004-02-10 Microaccess Medical Systems, Inc. Method and apparatus for transesophageal cardiovascular procedures
US6635073B2 (en) 2000-05-03 2003-10-21 Peter M. Bonutti Method of securing body tissue
US8764797B2 (en) * 2000-02-02 2014-07-01 Arthrex, Inc. Suture anchor with insert-molded suture eyelet
GB2359024A (en) 2000-02-09 2001-08-15 Anson Medical Ltd Fixator for arteries
US6527753B2 (en) 2000-02-29 2003-03-04 Olympus Optical Co., Ltd. Endoscopic treatment system
US7993368B2 (en) 2003-03-13 2011-08-09 C.R. Bard, Inc. Suture clips, delivery devices and methods
WO2001074260A1 (en) 2000-03-24 2001-10-11 Johns Hopkins University Peritoneal cavity device and method
US6805273B2 (en) 2002-11-04 2004-10-19 Federico Bilotti Surgical stapling instrument
US6572629B2 (en) 2000-08-17 2003-06-03 Johns Hopkins University Gastric reduction endoscopy
US6923824B2 (en) * 2000-09-12 2005-08-02 Axya Medical, Inc. Apparatus and method for securing suture to bone
AU2001293109A1 (en) 2000-09-25 2002-04-02 Angiotech Pharmaceuticals (Us), Inc. Resorbable anastomosis stents and plugs
US6755843B2 (en) 2000-09-29 2004-06-29 Olympus Optical Co., Ltd. Endoscopic suturing device
US6719763B2 (en) 2000-09-29 2004-04-13 Olympus Optical Co., Ltd. Endoscopic suturing device
US6551333B2 (en) 2000-10-19 2003-04-22 Ethicon Endo-Surgery, Inc. Method for attaching hernia mesh
JP4160386B2 (en) * 2000-11-02 2008-10-01 スミス アンド ネフュー インコーポレーテッド Tissue repair occlusion device and tissue repair method
US6974466B2 (en) 2000-12-06 2005-12-13 Wilson-Cook Medical Inc. Ligating band delivery apparatus
US6997931B2 (en) 2001-02-02 2006-02-14 Lsi Solutions, Inc. System for endoscopic suturing
US6770076B2 (en) 2001-02-12 2004-08-03 Opus Medical, Inc. Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device
US6535764B2 (en) 2001-05-01 2003-03-18 Intrapace, Inc. Gastric treatment and diagnosis device and method
US7879051B2 (en) 2001-05-18 2011-02-01 Christopher Paul Swain Flexible device for transfixing and joining tissue
US7144401B2 (en) 2001-06-07 2006-12-05 Olympus Optical Co., Ltd. Suturing device for endoscope
US7033379B2 (en) 2001-06-08 2006-04-25 Incisive Surgical, Inc. Suture lock having non-through bore capture zone
DE60226728D1 (en) 2001-06-15 2008-07-03 Donald J Hill DEVICE FOR ATTACHING AN OPERATION PATTERN
US7157636B2 (en) 2001-08-21 2007-01-02 Wu-Hong Hsieh Two-legged cymbal support for use with a cymbal assembly
JP3880907B2 (en) 2001-08-31 2007-02-14 オリンパス株式会社 Endoscopic suture device
US6652563B2 (en) * 2001-10-02 2003-11-25 Arthrex, Inc. Suture anchor with internal suture loop
US7118583B2 (en) 2001-10-23 2006-10-10 Arthrex, Inc. Meniscal suturing instrument and method
DE10158246C1 (en) 2001-11-28 2003-08-21 Ethicon Endo Surgery Europe Surgical stapling instrument
US20050090837A1 (en) 2003-03-25 2005-04-28 Sixto Robert Jr. Endoscopic surgical instrument having a force limiting actuator
JP2005514105A (en) 2001-12-31 2005-05-19 アレス ラボラトリーズ エルエルシー Hemostasis composition and method for controlling bleeding
US7150750B2 (en) * 2002-01-10 2006-12-19 Boston Scientific Scimed, Inc. Method and device for endoscopic suturing
US7618425B2 (en) 2002-01-30 2009-11-17 Olympus Corporation Endoscopic suturing system
US7530985B2 (en) 2002-01-30 2009-05-12 Olympus Corporation Endoscopic suturing system
US7344545B2 (en) 2002-01-30 2008-03-18 Olympus Corporation Endoscopic suturing system
US6988987B2 (en) 2002-03-18 2006-01-24 Olympus Corporation Guide tube
US20030225312A1 (en) 2002-03-18 2003-12-04 Anthony Kalloo Endoscopic system for treating inside of body cavity
US7527590B2 (en) 2002-03-19 2009-05-05 Olympus Corporation Anastomosis system
US7247161B2 (en) * 2002-03-22 2007-07-24 Gyrus Ent L.L.C. Powered surgical apparatus, method of manufacturing powered surgical apparatus, and method of using powered surgical apparatus
US6699263B2 (en) 2002-04-05 2004-03-02 Cook Incorporated Sliding suture anchor
US7335221B2 (en) 2002-04-12 2008-02-26 Ethicon, Inc. Suture anchoring and tensioning device and method for using same
US7122039B2 (en) 2002-05-01 2006-10-17 Boston Scientific Scimed, Inc. Tying knots
US7494496B2 (en) 2002-05-17 2009-02-24 Ucl Biomedica Plc Device for transfixing and joining tissue
AU2003248671B2 (en) 2002-06-12 2009-03-26 Boston Scientific Limited Suturing instruments
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US6972027B2 (en) 2002-06-26 2005-12-06 Stryker Endoscopy Soft tissue repair system
JP4373146B2 (en) 2002-07-11 2009-11-25 オリンパス株式会社 Endoscopic suturing device
US8066724B2 (en) 2002-09-12 2011-11-29 Medtronic, Inc. Anastomosis apparatus and methods
US8454628B2 (en) 2002-09-20 2013-06-04 Syntheon, Llc Surgical fastener aligning instrument particularly for transoral treatment of gastroesophageal reflux disease
US6966916B2 (en) 2002-09-26 2005-11-22 Kumar Sarbjeet S Device and method for surgical repair of abdominal wall hernias
US7323004B2 (en) 2002-09-30 2008-01-29 Ethicon, Inc. Device for providing automatic stitching of an incision
US8105345B2 (en) 2002-10-04 2012-01-31 Medtronic, Inc. Anastomosis apparatus and methods
US20060015125A1 (en) 2004-05-07 2006-01-19 Paul Swain Devices and methods for gastric surgery
US20040138683A1 (en) * 2003-01-09 2004-07-15 Walter Shelton Suture arrow device and method of using
US7076845B2 (en) * 2003-01-13 2006-07-18 Timothy T. Tylaska Mechanical knot apparatus
US20040249367A1 (en) * 2003-01-15 2004-12-09 Usgi Medical Corp. Endoluminal tool deployment system
US7780700B2 (en) 2003-02-04 2010-08-24 ev3 Endovascular, Inc Patent foramen ovale closure system
WO2004071284A1 (en) 2003-02-11 2004-08-26 Olympus Corporation Overtube, producing method and placing method of the same, and method of treating intra-abdominal cavity
JP4477382B2 (en) 2003-03-04 2010-06-09 オリンパス株式会社 Endoscopic intraperitoneal treatment system
GB0307826D0 (en) 2003-04-04 2003-05-07 Univ London A device for transfixing and joining tissue
US7431694B2 (en) 2003-05-16 2008-10-07 Ethicon Endo-Surgery, Inc. Method of guiding medical devices
US7380695B2 (en) 2003-05-20 2008-06-03 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a single lockout mechanism for prevention of firing
US7380696B2 (en) 2003-05-20 2008-06-03 Ethicon Endo-Surgery, Inc. Articulating surgical stapling instrument incorporating a two-piece E-beam firing mechanism
JP4145200B2 (en) 2003-06-06 2008-09-03 オリンパス株式会社 Suture device
US6918871B2 (en) 2003-06-19 2005-07-19 Ethicon Endo-Surgery, Inc. Method for accessing cavity
US7166116B2 (en) 2003-06-23 2007-01-23 Ethicon, Inc. Tissue grasper/suture passer instrument
US8216252B2 (en) 2004-05-07 2012-07-10 Usgi Medical, Inc. Tissue manipulation and securement system
US20050043749A1 (en) * 2003-08-22 2005-02-24 Coalescent Surgical, Inc. Eversion apparatus and methods
US7371244B2 (en) 2003-08-25 2008-05-13 Ethicon, Inc. Deployment apparatus for suture anchoring device
WO2005034763A1 (en) * 2003-09-11 2005-04-21 Nmt Medical, Inc. Devices, systems, and methods for suturing tissue
US8100923B2 (en) 2003-09-15 2012-01-24 Abbott Laboratories Suture locking device and methods
US7364061B2 (en) 2003-09-29 2008-04-29 Ethicon Endo-Surgery, Inc. Surgical stapling instrument incorporating a multistroke firing position indicator and retraction mechanism
US7217279B2 (en) 2003-11-14 2007-05-15 Ethicon, Inc. Suture loop anchor
US20070198033A1 (en) 2003-11-26 2007-08-23 Johns Hopkins University Peroral Transgastric Endoscopic Techniques
US20050251189A1 (en) 2004-05-07 2005-11-10 Usgi Medical Inc. Multi-position tissue manipulation assembly
US7361180B2 (en) 2004-05-07 2008-04-22 Usgi Medical, Inc. Apparatus for manipulating and securing tissue
WO2005058239A2 (en) * 2003-12-12 2005-06-30 Usgi Medical Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US7300451B2 (en) 2003-12-22 2007-11-27 Ethicon, Inc. Suture anchoring device
US20050154401A1 (en) * 2004-01-08 2005-07-14 Scimed Life Systems, Inc. Suturing device for implantable device
JP4643451B2 (en) 2004-01-08 2011-03-02 オリンパス株式会社 Anastomosis
US7211093B2 (en) 2004-01-14 2007-05-01 Lsi Solutions, Inc. Sew-right running stitch instrument
US8828025B2 (en) * 2004-02-13 2014-09-09 Ethicon Endo-Surgery, Inc. Methods and devices for reducing hollow organ volume
JP4643328B2 (en) 2004-04-07 2011-03-02 オリンパス株式会社 Medical ligature suturing device
US7833238B2 (en) * 2004-04-19 2010-11-16 Granit Medical Innovations, Llc Endoscopic anchoring device and associated method
US7390329B2 (en) 2004-05-07 2008-06-24 Usgi Medical, Inc. Methods for grasping and cinching tissue anchors
WO2005110280A2 (en) 2004-05-07 2005-11-24 Valentx, Inc. Devices and methods for attaching an endolumenal gastrointestinal implant
US7736374B2 (en) 2004-05-07 2010-06-15 Usgi Medical, Inc. Tissue manipulation and securement system
US7736378B2 (en) 2004-05-07 2010-06-15 Usgi Medical, Inc. Apparatus and methods for positioning and securing anchors
EP1762188B1 (en) 2004-05-11 2017-02-22 Olympus Corporation Surgical operation instrument
WO2005112784A2 (en) 2004-05-14 2005-12-01 Ethicon Endo-Surgery, Inc. Devices and methods for locking and cutting a suture in a medical procedure
US20060004409A1 (en) 2004-05-14 2006-01-05 Nobis Rudolph H Devices for locking and/or cutting a suture
JP4727295B2 (en) 2004-05-20 2011-07-20 オリンパス株式会社 Medical device and treatment system for living tissue
US8475476B2 (en) 2004-06-01 2013-07-02 Cook Medical Technologies Llc System and method for accessing a body cavity
US8206417B2 (en) 2004-06-09 2012-06-26 Usgi Medical Inc. Apparatus and methods for optimizing anchoring force
US7695493B2 (en) 2004-06-09 2010-04-13 Usgi Medical, Inc. System for optimizing anchoring force
US7736379B2 (en) 2004-06-09 2010-06-15 Usgi Medical, Inc. Compressible tissue anchor assemblies
US7678135B2 (en) 2004-06-09 2010-03-16 Usgi Medical, Inc. Compressible tissue anchor assemblies
US7931661B2 (en) 2004-06-14 2011-04-26 Usgi Medical, Inc. Apparatus and methods for performing transluminal gastrointestinal procedures
US7232448B2 (en) 2004-06-17 2007-06-19 Ethicon, Inc. - Usa Minimally invasive stitching device
US7367485B2 (en) 2004-06-30 2008-05-06 Ethicon Endo-Surgery, Inc. Surgical stapling instrument incorporating a multistroke firing mechanism having a rotary transmission
WO2006080951A2 (en) 2004-07-01 2006-08-03 Yale University Targeted and high density drug loaded polymeric materials
US20060020277A1 (en) 2004-07-20 2006-01-26 Gostout Christopher J Gastric reshaping devices and methods
US20060020274A1 (en) 2004-07-23 2006-01-26 Usgi Medical Inc. Manipulatable grasping needle
US7410086B2 (en) 2004-07-28 2008-08-12 Ethicon Endo-Surgery, Inc. Electroactive polymer-based actuation mechanism for circular stapler
US7407074B2 (en) 2004-07-28 2008-08-05 Ethicon Endo-Surgery, Inc. Electroactive polymer-based actuation mechanism for multi-fire surgical fastening instrument
US7407077B2 (en) 2004-07-28 2008-08-05 Ethicon Endo-Surgery, Inc. Electroactive polymer-based actuation mechanism for linear surgical stapler
US20060036267A1 (en) 2004-08-11 2006-02-16 Usgi Medical Inc. Methods and apparatus for performing malabsorptive bypass procedures within a patient's gastro-intestinal lumen
US20090326578A1 (en) 2004-09-30 2009-12-31 Usgi Medical, Inc. Interlocking tissue anchor apparatus and methods
JP2008516733A (en) 2004-10-18 2008-05-22 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション Endoscopic suture device and method
US8016839B2 (en) 2005-01-26 2011-09-13 Wilk Patent, Llc Intra-abdominal medical procedures and device
US20060178702A1 (en) * 2005-02-10 2006-08-10 Inion Ltd. Apparatus for attaching sutures
WO2006101715A2 (en) 2005-03-18 2006-09-28 Wilk Patent, Llc Intra-abdominal medical device and associated method
US20060212063A1 (en) 2005-03-18 2006-09-21 Wilk Patent, Llc Surgical device and associated trans-organ surgical method
US20060258909A1 (en) 2005-04-08 2006-11-16 Usgi Medical, Inc. Methods and apparatus for maintaining sterility during transluminal procedures
US20060241691A1 (en) 2005-04-12 2006-10-26 Wilk Patent, Llc Medical treatment method and device utilizing magnetic elements
US7963941B2 (en) 2005-04-12 2011-06-21 Wilk Peter J Intra-abdominal medical method and associated device
US20060241480A1 (en) 2005-04-12 2006-10-26 Wilk Patent, Llc Endoscopic medical method and associated device
US20060241344A1 (en) 2005-04-12 2006-10-26 Wilk Patent, Llc Intra-abdominal surgical method and associated apparatus
US8333777B2 (en) * 2005-04-22 2012-12-18 Benvenue Medical, Inc. Catheter-based tissue remodeling devices and methods
US7785251B2 (en) 2005-04-22 2010-08-31 Wilk Patent, Llc Port extraction method for trans-organ surgery
US20060241651A1 (en) 2005-04-22 2006-10-26 Wilk Patent, Llc Surgical port device and associated method
US20060252997A1 (en) 2005-04-22 2006-11-09 Wilk Patent, Llc Medical port device, kit and associated method
US20060241570A1 (en) 2005-04-22 2006-10-26 Wilk Patent, Llc Intra-abdominal medical method
US20060237023A1 (en) 2005-04-26 2006-10-26 Usgi Medical Inc. Transgastric tubal ligation
US8663236B2 (en) 2005-04-26 2014-03-04 Usgi Medical Inc. Transgastric abdominal access
US8628541B2 (en) 2005-05-26 2014-01-14 Usgi Medical, Inc. Methods and apparatus for securing and deploying tissue anchors
US9585651B2 (en) 2005-05-26 2017-03-07 Usgi Medical, Inc. Methods and apparatus for securing and deploying tissue anchors
US7615060B2 (en) 2005-06-13 2009-11-10 Ethicon-Endo Surgery, Inc. Endoscopic suturing device
US7641836B2 (en) 2005-06-23 2010-01-05 Ethicon, Inc. Tissue repair device and fabrication thereof
US7622068B2 (en) 2005-06-23 2009-11-24 Ethicon, Inc. Tissue repair device and fabrication thereof
US8579176B2 (en) 2005-07-26 2013-11-12 Ethicon Endo-Surgery, Inc. Surgical stapling and cutting device and method for using the device
US8679154B2 (en) 2007-01-12 2014-03-25 Ethicon Endo-Surgery, Inc. Adjustable compression staple and method for stapling with adjustable compression
US8021355B2 (en) 2005-08-12 2011-09-20 Board Of Regents The University Of Texas System System, kit, and method of transgastric removal of visceral fat and other related methods
US7846179B2 (en) 2005-09-01 2010-12-07 Ovalis, Inc. Suture-based systems and methods for treating septal defects
US7722631B2 (en) * 2005-09-28 2010-05-25 Olympus Medical Systems Corporation Method for suturing perforation
US7357287B2 (en) 2005-09-29 2008-04-15 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having preloaded firing assistance mechanism
US20070123840A1 (en) 2005-10-18 2007-05-31 Usgi Medical, Inc. Instrument assisted abdominal access
US20070112362A1 (en) 2005-11-14 2007-05-17 Olympus Medical Systems Corp. Perforation suturing method
US7850712B2 (en) * 2005-11-15 2010-12-14 Ethicon Endo-Surgery, Inc. Self-shielding suture anchor
US20070156175A1 (en) 2005-12-29 2007-07-05 Weadock Kevin S Device for attaching, relocating and reinforcing tissue and methods of using same
US8475361B2 (en) 2006-01-06 2013-07-02 Olympus Medical Systems Corp. Percutaneous or natural-orifice medical procedure and system therefor
US20070162052A1 (en) 2006-01-06 2007-07-12 Olympus Medical Systems Corp. Loading device for indwelling implement
US20070260214A1 (en) 2006-01-13 2007-11-08 Olympus Medical Systems Corp. Medical procedure through natural body opening
US20070167675A1 (en) 2006-01-13 2007-07-19 Olympus Medical Systems Corp. Overtube and medical procedure via natural orifice using the same
US20080255422A1 (en) 2006-01-13 2008-10-16 Olympus Medical Systems Corp. Medical device
US20070167676A1 (en) 2006-01-13 2007-07-19 Olympus Medical Systems Corp. Overtube and medical procedure via natural orifice using the same
TW200744517A (en) 2006-01-13 2007-12-16 Olympus Medical Systems Corp Overtube used in endoscope
US7785333B2 (en) 2006-02-21 2010-08-31 Olympus Medical Systems Corp. Overtube and operative procedure via bodily orifice
US20070163585A1 (en) 2006-01-13 2007-07-19 Olympus Medical Systems Corp. Method for accessing abdominal cavity and medical procedure via natural orifice
US20070163604A1 (en) 2006-01-13 2007-07-19 Olympus Medical Systems Corp. Leak test method for medical procedure via natural orifice
US20070219411A1 (en) 2006-01-13 2007-09-20 Olympus Medical Systems Corp. Overtube and endoscopic treatment system
US20070167967A1 (en) 2006-01-13 2007-07-19 Olympus Medical Systems Corp. Medical procedure via natural orifice and puncture device
US7735489B2 (en) 2006-01-13 2010-06-15 Olympus Medical Systems Corp. Endotracheal tube, device for use in medical procedure through natural opening and medical procedure through natural opening
US20070213702A1 (en) 2006-03-08 2007-09-13 Olympus Medical Systems Corp. Medical procedure carried out via a natural opening
US8002695B2 (en) 2006-01-13 2011-08-23 Olympus Medical Systems Corp. Medical procedure via natural opening
US8241279B2 (en) 2006-02-23 2012-08-14 Olympus Medical Systems Corp. Overtube and natural opening medical procedures using the same
US8728121B2 (en) 2006-01-13 2014-05-20 Olympus Medical Systems Corp. Puncture needle and medical procedure using puncture needle that is performed via natural orifice
US8721657B2 (en) 2006-01-13 2014-05-13 Olympus Medical Systems Corp. Medical instrument
US7422139B2 (en) 2006-01-31 2008-09-09 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting fastening instrument with tactile position feedback
US7416101B2 (en) 2006-01-31 2008-08-26 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with loading force feedback
US20070213749A1 (en) 2006-03-08 2007-09-13 Olympus Medical Systems Corp. Medical procedure performed inside abdominal cavity
US20070225734A1 (en) 2006-03-22 2007-09-27 Minos Medical Systems and methods for less invasive resolution of maladies of tissue including the appendix, gall bladder, and hemorrhoids
US7731727B2 (en) 2006-04-26 2010-06-08 Lsi Solutions, Inc. Medical instrument to place a pursestring suture, open a hole and pass a guidewire
WO2007136820A2 (en) 2006-05-18 2007-11-29 Aponos Medical Corp. Multifunctional instrument introducer
US7758598B2 (en) 2006-05-19 2010-07-20 Ethicon Endo-Surgery, Inc. Combination knotting element and suture anchor applicator
US20070270629A1 (en) 2006-05-19 2007-11-22 Charles Filipi J System and techniques for magnetic manipulation of internal organs during minimally invasive surgery
CN104688349B (en) 2006-06-13 2017-05-10 直观外科手术操作公司 Minimally invasive surgical system
US7736376B2 (en) 2006-07-05 2010-06-15 Olympus Medical Systems Corp. Living body wall fixing tool used in endoscope
US8870916B2 (en) 2006-07-07 2014-10-28 USGI Medical, Inc Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use
US7815566B2 (en) 2006-07-20 2010-10-19 Ethicon Endo-Surgery, Inc. Methods for stabilizing and positioning an endoscope and surgical procedures
US20080027272A1 (en) 2006-07-26 2008-01-31 Terumo Cardiovascular Systems Corporation Device for processing blood vessel harvested for bypass graft surgery
US7837455B2 (en) 2006-07-28 2010-11-23 Ethicon, Inc. Apparatus and method for making suture packages
US20080058710A1 (en) 2006-08-15 2008-03-06 Wilk Peter J Surgical kit, closure device, and associated method
US20080058865A1 (en) 2006-08-21 2008-03-06 Wilk Peter J Surgical closure device and associated method
US7674275B2 (en) 2006-10-05 2010-03-09 Ethicon Endo-Surgery, Inc. Suture anchor
JP4584230B2 (en) 2006-11-14 2010-11-17 オリンパスメディカルシステムズ株式会社 Clip device
US8221443B2 (en) 2006-11-15 2012-07-17 Mayo Foundation For Medical Education And Research Submucosal endoscopy with mucosal flap methods and kits
US8025670B2 (en) 2006-11-22 2011-09-27 Minos Medical Methods and apparatus for natural orifice vaginal hysterectomy
US8114100B2 (en) 2006-12-06 2012-02-14 Ethicon Endo-Surgery, Inc. Safety fastener for tissue apposition
JP2008161570A (en) 2006-12-28 2008-07-17 Olympus Medical Systems Corp Ultrasonic endoscope system
US20080171907A1 (en) 2007-01-12 2008-07-17 Ethicon Endo-Surgery, Inc. Magnetic Tissue Grasping
WO2008088982A1 (en) 2007-01-16 2008-07-24 Board Of Regents, The University Of Texas System Needle-electrode and tissue anchor system
JP5297816B2 (en) 2007-01-26 2013-09-25 オリンパスメディカルシステムズ株式会社 Gripping device
US20080183039A1 (en) 2007-01-26 2008-07-31 Ethicon Endo-Surgery, Inc. Balloon Positioning System for Endoscopic Access
US8460314B2 (en) 2007-02-26 2013-06-11 Olympus Medical Systems Corp. Application of procedure through natural orifice
US20080208214A1 (en) 2007-02-26 2008-08-28 Olympus Medical Systems Corp. Applicator and tissue fastening method through natural orifice
US7780702B2 (en) 2007-02-27 2010-08-24 Olympus Medical Systems Corp. Suture tool
US8308766B2 (en) 2007-02-27 2012-11-13 Olympus Medical Systems Corp. Endoscopic treatment instrument
US8128657B2 (en) 2007-02-27 2012-03-06 Olympus Medical Systems Corp. Suture instrument
US7815662B2 (en) 2007-03-08 2010-10-19 Ethicon Endo-Surgery, Inc. Surgical suture anchors and deployment device
US20080228203A1 (en) 2007-03-15 2008-09-18 Minos Medical System and method for translumenal closure in natural orifice surgery
US20080228199A1 (en) 2007-03-16 2008-09-18 Ethicon Endo-Surgery, Inc. Endoscopic tissue approximation method
US20080228202A1 (en) 2007-03-16 2008-09-18 Ethicon Endo-Surgery, Inc. Endoscopic tissue approximation system
JP4996311B2 (en) 2007-04-05 2012-08-08 オリンパスメディカルシステムズ株式会社 Treatment instrument system
US20080262525A1 (en) 2007-04-17 2008-10-23 Usgi Medical, Inc. Tissue penetration and grasping apparatus
US8500629B2 (en) * 2007-04-30 2013-08-06 Ethicon Endo-Surgery, Inc. Endoscopic device
US8631991B2 (en) 2007-05-30 2014-01-21 Ethicon Endo-Surgery, Inc. Surgical instrument
US7699871B2 (en) * 2007-05-30 2010-04-20 Ethicon Endo-Surgery, Inc. Surgical instrument
US8740937B2 (en) 2007-05-31 2014-06-03 Cook Medical Technologies Llc Suture lock
US8992569B2 (en) 2007-06-29 2015-03-31 Ethicon Endo-Surgery, Inc. Insertion device and method of use
USD576278S1 (en) 2007-07-16 2008-09-02 Ethicon Endo-Surgery, Inc. Surgical stapler
US8551118B2 (en) 2007-07-18 2013-10-08 Ethicon Endo-Surgery, Inc. Hybrid endoscopic/laparoscopic method for forming serosa to serosa plications in a gastric cavity
US7998150B2 (en) 2007-09-28 2011-08-16 Olympus Medical Systems Corp. Suturing device
US9526487B2 (en) * 2007-12-05 2016-12-27 Indiana University Research & Technology Corporation Methods and apparatuses for delivering anchoring devices into body passage walls
US8652150B2 (en) 2008-05-30 2014-02-18 Ethicon Endo-Surgery, Inc. Multifunction surgical device
US8361112B2 (en) 2008-06-27 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical suture arrangement
US9943302B2 (en) 2008-08-12 2018-04-17 Covidien Lp Medical device for wound closure and method of use
US9089320B2 (en) 2008-09-25 2015-07-28 Ethicon Endo-Surgery, Inc. Methods and devices for delivering and applying multiple suture anchors
US8480686B2 (en) 2008-09-25 2013-07-09 Ethicon Endo-Surgery, Inc. Methods and devices for delivering and applying suture anchors
US8262675B2 (en) 2008-10-29 2012-09-11 Ethicon Endo-Surgery, Inc. Methods and devices for applying multiple suture anchors
US20100113873A1 (en) 2008-11-06 2010-05-06 Takayuki Suzuki Suturing device and suturing system
WO2010085456A1 (en) 2009-01-20 2010-07-29 Guided Delivery Systems Inc. Anchor deployment devices and related methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012504482A (en) * 2008-10-06 2012-02-23 ウィルソン−クック・メディカル・インコーポレーテッド End cap for secure deployment of tissue anchors
WO2010065728A1 (en) * 2008-12-05 2010-06-10 Wilson-Cook Medical, Inc. Tissue anchors for purse-string closure of perforations
JP2012510870A (en) * 2008-12-05 2012-05-17 クック メディカル テクノロジーズ エルエルシー Tissue anchor that closes the hole in a drawstring fashion
US8377095B2 (en) 2008-12-05 2013-02-19 Cook Medical Technologies, LLC Tissue anchors for purse-string closure of perforations
AU2009322353B2 (en) * 2008-12-05 2013-04-18 Cook Medical Technologies Llc Tissue anchors for purse-string closure of perforations
US8647368B2 (en) 2009-04-03 2014-02-11 Cook Medical Technologies Llc Tissue anchors and medical devices for rapid deployment of tissue anchors
JP2013517108A (en) * 2010-01-20 2013-05-16 ニュー ホープ ベンチャーズ，リミティド パートナーシップ Tissue occlusion device and method
US9050065B2 (en) 2010-01-20 2015-06-09 Micro Interventional Devices, Inc. Tissue repair implant and delivery device and method
US9980708B2 (en) 2010-01-20 2018-05-29 Micro Interventional Devices, Inc. Tissue closure device and method
US10058314B2 (en) 2010-01-20 2018-08-28 Micro Interventional Devices, Inc. Tissue closure device and method
US10743854B2 (en) 2010-01-20 2020-08-18 Micro Interventional Devices, Inc. Tissue closure device and method
US10959840B2 (en) 2010-01-20 2021-03-30 Micro Interventional Devices, Inc. Systems and methods for affixing a prosthesis to tissue

Also Published As

Publication number Publication date
CA2671030C (en) 2013-10-08
JP5270565B2 (en) 2013-08-21
EP2094167A2 (en) 2009-09-02
WO2008067384A3 (en) 2008-09-25
AU2007325204B2 (en) 2013-06-06
US20080132948A1 (en) 2008-06-05
JP2010511436A (en) 2010-04-15
ATE514382T1 (en) 2011-07-15
EP2094167B1 (en) 2011-06-29
CA2671030A1 (en) 2008-06-05
US8551139B2 (en) 2013-10-08
AU2007325204A1 (en) 2008-06-05

Similar Documents

Publication Publication Date Title
CA2671030C (en) Visceral anchors for purse-string closure of perforations
JP2010511436A5 (en)
US8317679B2 (en) Endcap for safely deploying tissue anchors
EP2429374B1 (en) Medical device for suturing perforations
US8152836B2 (en) Visceral staples for purse-string closure of perforations
EP2413810B1 (en) Tissue anchors and medical devices for rapid deployment of tissue anchors
US9339265B2 (en) Medical devices, systems, and methods for using tissue anchors
CA2584405A1 (en) Apparatus and method of endoscopic suturing
AU2009302589B2 (en) Endcap for safely deploying tissue anchors
AU2010232538B2 (en) Tissue anchors and medical devices for rapid deployment of tissue anchors

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07868914

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2671030

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2009539460

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007325204

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2007868914

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2007325204

Country of ref document: AU

Date of ref document: 20071128

Kind code of ref document: A