WO2008067069A3 - Mitogen activated protein kinase phosphatase 4 (mkp4) and methods of use thereof - Google Patents

Mitogen activated protein kinase phosphatase 4 (mkp4) and methods of use thereof Download PDF

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Publication number
WO2008067069A3
WO2008067069A3 PCT/US2007/081954 US2007081954W WO2008067069A3 WO 2008067069 A3 WO2008067069 A3 WO 2008067069A3 US 2007081954 W US2007081954 W US 2007081954W WO 2008067069 A3 WO2008067069 A3 WO 2008067069A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
mkp4
protein kinase
activated protein
mitogen activated
Prior art date
Application number
PCT/US2007/081954
Other languages
French (fr)
Other versions
WO2008067069A2 (en
Inventor
Molly Kulesz-Martin
Yuangang Liu
Original Assignee
Univ Oregon Health & Science
Molly Kulesz-Martin
Yuangang Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oregon Health & Science, Molly Kulesz-Martin, Yuangang Liu filed Critical Univ Oregon Health & Science
Publication of WO2008067069A2 publication Critical patent/WO2008067069A2/en
Publication of WO2008067069A3 publication Critical patent/WO2008067069A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)

Abstract

Compositions and methods are provided for treating cancer, particularly skin cancer.
PCT/US2007/081954 2006-10-19 2007-10-19 Mitogen activated protein kinase phosphatase 4 (mkp4) and methods of use thereof WO2008067069A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85280706P 2006-10-19 2006-10-19
US60/852,807 2006-10-19

Publications (2)

Publication Number Publication Date
WO2008067069A2 WO2008067069A2 (en) 2008-06-05
WO2008067069A3 true WO2008067069A3 (en) 2008-11-20

Family

ID=39468578

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/081954 WO2008067069A2 (en) 2006-10-19 2007-10-19 Mitogen activated protein kinase phosphatase 4 (mkp4) and methods of use thereof

Country Status (1)

Country Link
WO (1) WO2008067069A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014368925A1 (en) * 2013-12-20 2016-07-21 Biomed Valley Discoveries, Inc. Cancer treatments using combinations of MEK type I and ERK inhibitors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030022857A1 (en) * 2001-07-05 2003-01-30 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment of body weight disorders, including obesity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030022857A1 (en) * 2001-07-05 2003-01-30 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment of body weight disorders, including obesity

Also Published As

Publication number Publication date
WO2008067069A2 (en) 2008-06-05

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