WO2008043426A3 - Komponenten und verfahren zur enzymatischen synthese von nukleinsäuren - Google Patents
Komponenten und verfahren zur enzymatischen synthese von nukleinsäuren Download PDFInfo
- Publication number
- WO2008043426A3 WO2008043426A3 PCT/EP2007/008198 EP2007008198W WO2008043426A3 WO 2008043426 A3 WO2008043426 A3 WO 2008043426A3 EP 2007008198 W EP2007008198 W EP 2007008198W WO 2008043426 A3 WO2008043426 A3 WO 2008043426A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acids
- enzymatic synthesis
- components
- nucleotide analogues
- enzymatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Die Anmeldung betrifft Nukleotid-Analoga, die einen makromolekularen sterisch anspruchsvollen Liganden und einen Marker enthalten. Die Nukleotid-Analoga der Erfindung können zur enzymatischen Synthese und Sequenzierung von Nukleinsäuren verwendet werden.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07818288A EP2074133A2 (de) | 2006-09-20 | 2007-09-20 | Komponenten und verfahren zur enzymatischen synthese von nukleinsäuren |
US12/442,184 US20100304368A1 (en) | 2006-09-20 | 2007-09-20 | Components and method for enzymatic synthesis of nucleic acids |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006044749 | 2006-09-20 | ||
DE102006044749.2 | 2006-09-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008043426A2 WO2008043426A2 (de) | 2008-04-17 |
WO2008043426A3 true WO2008043426A3 (de) | 2009-05-28 |
Family
ID=39060313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2007/008198 WO2008043426A2 (de) | 2006-09-20 | 2007-09-20 | Komponenten und verfahren zur enzymatischen synthese von nukleinsäuren |
Country Status (3)
Country | Link |
---|---|
US (1) | US20100304368A1 (de) |
EP (1) | EP2074133A2 (de) |
WO (1) | WO2008043426A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9315860B2 (en) | 2009-10-26 | 2016-04-19 | Genovoxx Gmbh | Conjugates of nucleotides and method for the application thereof |
US9994894B2 (en) | 2011-04-27 | 2018-06-12 | Agct Gmbh | Method and components for detecting nucleic acid chains |
EP2705161A1 (de) | 2011-05-04 | 2014-03-12 | Genovoxx GmbH | Nukleosid-triphosphat-konjugate und methoden zu deren anwendung |
GB2497317A (en) * | 2011-12-06 | 2013-06-12 | Univ Dublin | System and method for the detection of analytes using rod-shaped nanoparticles |
EP2768972B2 (de) | 2011-09-23 | 2020-07-22 | Illumina, Inc. | Verfahren und zusammensetzungen zur nucleinsäuresequenzierung |
DE102012217603A1 (de) | 2012-09-27 | 2014-03-27 | Siemens Aktiengesellschaft | Anordnung zur Nukleinsäure-Sequenzierung mittels Tunnelstromanalyse |
US11384377B2 (en) | 2013-04-02 | 2022-07-12 | Molecular Assemblies, Inc. | Reusable initiators for synthesizing nucleic acids |
US8808989B1 (en) * | 2013-04-02 | 2014-08-19 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
US9771613B2 (en) | 2013-04-02 | 2017-09-26 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acid |
US11331643B2 (en) | 2013-04-02 | 2022-05-17 | Molecular Assemblies, Inc. | Reusable initiators for synthesizing nucleic acids |
US9279149B2 (en) | 2013-04-02 | 2016-03-08 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
US10683536B2 (en) * | 2013-04-02 | 2020-06-16 | Molecular Assemblies, Inc. | Reusable initiators for synthesizing nucleic acids |
US9845493B2 (en) | 2013-04-19 | 2017-12-19 | Agency For Science, Technology And Research | Tunable fluorescence using cleavable linkers |
WO2016028803A2 (en) * | 2014-08-18 | 2016-02-25 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
EP3463381A4 (de) | 2016-05-23 | 2020-01-01 | The Trustees of Columbia University in the City of New York | Nukleotidderivate und verfahren zur verwendung davon |
WO2020160122A1 (en) * | 2019-01-29 | 2020-08-06 | Molecular Assemblies, Inc. | Reusable initiators for synthesizing nucleic acids |
WO2024108376A1 (zh) * | 2022-11-22 | 2024-05-30 | 深圳华大智造科技股份有限公司 | 试剂盒及其在测序中的应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988002784A1 (en) * | 1986-10-17 | 1988-04-21 | Wallac Oy | Hybridization assay and means to be used in the assay |
US20030054396A1 (en) * | 2001-09-07 | 2003-03-20 | Weiner Michael P. | Enzymatic light amplification |
WO2003048178A2 (en) * | 2001-11-29 | 2003-06-12 | Amersham Biosciences Uk Limited | Nucleotide analogues and their use for nucleic acid sequencing |
WO2004092331A2 (en) * | 2003-04-08 | 2004-10-28 | Li-Cor, Inc. | Composition and method for nucleic acid sequencing |
WO2005044836A2 (de) * | 2003-11-05 | 2005-05-19 | Genovoxx Gmbh | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
WO2006097320A2 (de) * | 2005-03-17 | 2006-09-21 | Genovoxx Gmbh | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040248150A1 (en) * | 1999-04-02 | 2004-12-09 | Sharat Singh | Methods employing oligonucleotide-binding e-tag probes |
US20030207300A1 (en) * | 2000-04-28 | 2003-11-06 | Matray Tracy J. | Multiplex analytical platform using molecular tags |
-
2007
- 2007-09-20 EP EP07818288A patent/EP2074133A2/de not_active Withdrawn
- 2007-09-20 US US12/442,184 patent/US20100304368A1/en not_active Abandoned
- 2007-09-20 WO PCT/EP2007/008198 patent/WO2008043426A2/de active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988002784A1 (en) * | 1986-10-17 | 1988-04-21 | Wallac Oy | Hybridization assay and means to be used in the assay |
US20030054396A1 (en) * | 2001-09-07 | 2003-03-20 | Weiner Michael P. | Enzymatic light amplification |
WO2003048178A2 (en) * | 2001-11-29 | 2003-06-12 | Amersham Biosciences Uk Limited | Nucleotide analogues and their use for nucleic acid sequencing |
WO2004092331A2 (en) * | 2003-04-08 | 2004-10-28 | Li-Cor, Inc. | Composition and method for nucleic acid sequencing |
WO2005044836A2 (de) * | 2003-11-05 | 2005-05-19 | Genovoxx Gmbh | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
WO2006097320A2 (de) * | 2005-03-17 | 2006-09-21 | Genovoxx Gmbh | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
Also Published As
Publication number | Publication date |
---|---|
WO2008043426A2 (de) | 2008-04-17 |
EP2074133A2 (de) | 2009-07-01 |
US20100304368A1 (en) | 2010-12-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2008043426A3 (de) | Komponenten und verfahren zur enzymatischen synthese von nukleinsäuren | |
EP2094867A4 (de) | Verfahren und zusammensetzungen für den nachweis einer nukleinsäure mittels spaltreaktion | |
WO2006007207A3 (en) | Methods and devices for nucleic acid sequence determination | |
EP2089517A4 (de) | Polymeraseenzyme und reagenzien für erweiterte nukeinsäuresequenzierung | |
WO2007062160A8 (en) | Methods and compositions for sequencing a nucleic acid | |
WO2007057167A3 (en) | A method for enhancing enzymatic dna polymerase reactions | |
WO2008054543A3 (en) | Oligonucleotides for multiplex nucleic acid assembly | |
MX2009007999A (es) | Hidrolisis de almidon utilizando fitasa con una alfa amilasa. | |
HK1154636A1 (en) | Preparation of templates for nucleic acid sequencing | |
WO2008094902A3 (en) | Compositions and methods for the detection of a nucleic acid using a cleavage reaction | |
EP2139992A4 (de) | Verfahren zur modulation der aktivität eines nukleinsäuremoleküls | |
EP2050819A4 (de) | Nukleotidsequenz-amplifikationsverfahren | |
ATE445019T1 (de) | Verfahren zur enzymatischen herstellung von (s)-3-cyano-5-methylhexansäure | |
EP2130924A4 (de) | Verfahren zur herstellung von l-aminosäure oder nukleinsäure | |
EP1992689A4 (de) | Verfahren zur extraktion von nukleinsäure aus biologischem material | |
WO2008073378A3 (en) | High throughput dna sequencing method and apparatus | |
GB2463170B (en) | Method for increasing the speed of nucleic acid amplification reactions | |
WO2006074334A3 (en) | Identification of rna targets using helicases | |
DE112006003704A5 (de) | DNA-Konstrukte zur spezifischen Hemmung der Genexpression durch RNA-Interferenz | |
EP1989332A4 (de) | Verfahren für nukleinsäureextraktion | |
WO2008016906A3 (en) | 3'-phosphate-labeled nucleotide analogs and their use for sequencing a nucleic acid | |
ATE554181T1 (de) | Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten unter kontinuierlicher cofaktor regenerierung | |
GB0711618D0 (en) | Method for determining the concentration of nucleic acids | |
DE502006009367D1 (de) | Verfahren zur enantioselektiven enzymatischen Reduktion von Ketoverbindungen | |
EP1838856A4 (de) | Verfahren zur zuführung von nukleinsäuren an periphere neuronen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 07818288 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2007818288 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12442184 Country of ref document: US |