WO2008043196A1 - Système en réseau à intensité modulée conçu pour compenser la désintégration d'un réseau en nid d'abeille et procédé d'utilisation associé - Google Patents

Système en réseau à intensité modulée conçu pour compenser la désintégration d'un réseau en nid d'abeille et procédé d'utilisation associé Download PDF

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Publication number
WO2008043196A1
WO2008043196A1 PCT/CN2006/002497 CN2006002497W WO2008043196A1 WO 2008043196 A1 WO2008043196 A1 WO 2008043196A1 CN 2006002497 W CN2006002497 W CN 2006002497W WO 2008043196 A1 WO2008043196 A1 WO 2008043196A1
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WO
WIPO (PCT)
Prior art keywords
needle
direct
honeycomb array
grating system
array intensity
Prior art date
Application number
PCT/CN2006/002497
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English (en)
Chinese (zh)
Inventor
Qiaosheng Wang
Original Assignee
Qiaosheng Wang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiaosheng Wang filed Critical Qiaosheng Wang
Priority to PCT/CN2006/002497 priority Critical patent/WO2008043196A1/fr
Publication of WO2008043196A1 publication Critical patent/WO2008043196A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1042X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head

Definitions

  • the present invention relates to a medical radiation therapy device, and more particularly to a direct-compensated honeycomb array intensity-modulating grating system for a radiation therapy device for tumor radiation therapy and a method for using the same.
  • An object of the present invention is to provide a direct-compensated honeycomb array intensity modulated grating system with high conformal field accuracy, good performance and good quality, and a method for using the same.
  • the present invention provides a direct-compensated decay honeycomb array intensity-modulating grating system comprising a rail mechanism, a grating mechanism fixed to the rail mechanism, and a driving mechanism for driving the rail mechanism, and the rail mechanism has a guide rail.
  • the grating mechanism includes a needle magazine and a plurality of tungsten needles.
  • the needle magazine is mounted on the guide rail, and the needle magazine is formed with a plurality of pinhole chambers, and the plurality of tungsten needles are detachably mounted in the needle hole chamber according to the shape of the object to be irradiated.
  • the method for using the above-mentioned direct-compensation type honeycomb array intensity-modulating grating system comprises the following steps:
  • the driving mechanism drives the rail mechanism so that the rail of the rail mechanism transports the needle magazine to the needle loading device, and the corresponding tungsten needle is installed in the needle hole corresponding to the needle box according to the shape of the object to be irradiated;
  • the drive mechanism drives the rail mechanism so that the guide rail mechanism guides the needle magazine to the designated position for radiotherapy.
  • the present invention provides another direct-compensation type honeycomb array intensity-modulating grating system, comprising a rail mechanism, a grating mechanism fixed on the rail mechanism, and a driving mechanism for driving the rail mechanism.
  • the rail mechanism has a plurality of rails that are disposed in an overlapping manner in the radial direction.
  • the grating mechanism includes a plurality of needle magazines and a plurality of tungsten needles. Each of the needle magazines is respectively disposed on the corresponding rails, and each of the needle magazines is formed with a plurality of pinhole chambers, and the plurality of tungsten needles are detachably installed in the needle hole chambers of the corresponding needle cartridges according to the shape of the objects to be irradiated.
  • the grating mechanism of the direct-compensated honeycomb array intensity-modulating grating system of the present invention adopts a honeycomb needle magazine and a structure of a plurality of tungsten needles, and selectively installs tungsten of different specifications into the corresponding pinhole chamber.
  • the needle so as to achieve conformal and intensity adjustment, therefore, the direct complement decay honeycomb array intensity modulation grating system has high conformity and high performance and good quality.
  • FIG. 1 is a top plan view of a first embodiment of a direct-compensated honeycomb array intensity modulated grating system of the present invention.
  • Fig. 2 is a front elevational view showing the rail mechanism and the grating mechanism of the direct-compensated honeycomb array' intensity-modulating grating system shown in Fig. 1.
  • Figure 3 is a perspective view of the needle magazine of the grating mechanism of Figure 2.
  • Figure 4 is a perspective view of a plurality of gauge pins of the grating mechanism of Figure 2.
  • Figure 5 is a cross-sectional view of the needle magazine shown in Figure 3.
  • Figure 6 is a plan view of the needle magazine shown in Figure 3.
  • Figure 7 is a cross-sectional view of the needle magazine of Figure 3 after the tungsten needle is installed.
  • Figure 8 is a plan view of the needle magazine shown in Figure 3 after the needle is mounted.
  • Figure 9 is a front elevational view of the drive mechanism of the direct-compensated honeycomb array intensity modulated grating system of Figure 1.
  • Fig. 10 is a front elevational view showing the rail mechanism and the grating mechanism of the second embodiment of the direct-compensated honeycomb array intensity-modulating grating system of the present invention.
  • FIG. 11 is a top plan view of a second embodiment of a bee direct-compensated honeycomb array intensity modulated grating system of the present invention.
  • Figure 12 is a partial cross-sectional view of the direct-compensated honeycomb array intensity modulated grating system of Figure 11.
  • Figure 13 is a perspective view of the rail mechanism shown in Figure 10.
  • Figure 14 is a cross-sectional view of the rail mechanism shown in Figure 13.
  • Fig. 15 is a plan view showing the needle holder of the grating mechanism shown in Fig. 10 after the tungsten needle is attached.
  • Figure 16 is a cross-sectional view of the needle magazine of Figure 10 after the tungsten needle is attached.
  • Figure 17 is a front elevational view showing the rail mechanism and the grating mechanism of the third embodiment of the direct-compensated honeycomb array intensity-modulated grating system of the present invention.
  • DETAILED DESCRIPTION OF THE INVENTION Figure 1 discloses a first embodiment of a direct complement decay honeycomb array intensity modulated grating system 10 of the present invention.
  • the direct-compensation decay honeycomb array intensity-modulating grating system 10 includes a rail mechanism 100, which is fixed.
  • the rail mechanism 100 has a circular guide rail 110.
  • a needle chamber 111 is opened on the guide rail 110.
  • the guide rail 110 is rotated about a shaft by the drive mechanism 300 to transport the grating mechanism 200 to or away from the position where the tumor is irradiated.
  • the guide rail 110 may also be in the shape of a straight rod.
  • the grating mechanism 200 includes a needle cartridge 210, a plurality of tungsten needles 221, 222, 223, 224, a needle loading device 230, and a needle withdrawal device 240.
  • the needle magazine 210 is mounted in the needle chamber 111 of the guide rail 110, and the needle magazine 210 moves with the guide rail 110.
  • the needle cartridge 210 is in the shape of a hexahedron, and the upper and lower surfaces thereof are spherical.
  • the needle cartridge 210 is divided by the metal piece 211 to form a separate pinhole chamber 212 arranged in a matrix of ⁇ ⁇ N matrix.
  • the pinhole chamber 212 has a tapered shape, and the pinhole chamber 212 has a regular hexagonal cross section.
  • Each of the pinhole chambers 212 is inclined toward a center on which the radiation source is disposed.
  • tungsten needles 221, 222, 223, and 224 have different lengths.
  • Each tungsten needle has a pyramid shape, and each tungsten needle has a regular hexagonal cross section.
  • Different sizes of tungsten needles 221, 222, 223, and 224 are detachably mounted in the corresponding pinhole chambers 212 as the case may be.
  • the needle loading device 230 and the needle withdrawal device 240 are disposed on the outer side and the inner side of the guide rail 210, respectively.
  • the needle loading device 230 inserts tungsten needles 221, 222, 223, 224 of different specifications into the corresponding pinhole chamber 212 to form a shape with the tumor.
  • a uniform thickness of the bismuth alloy layer is achieved for the purpose of illumination conformation and dose strength adjustment, as shown in Figures 7 and 8.
  • the drive mechanism 300 includes a motor 310, a gear assist 320, a worm gear housing 330, a base 340, a worm gear 350, and a gear 360 connector 370.
  • the motor 310 is mounted on the base 340, and the front end of the motor 310 is connected to the connector 370.
  • the connector 370 is in turn coupled to a worm gear 350 that is disposed on a worm gear housing 330.
  • the worm gear housing 330 is disposed on the housing 340, the worm gear 350 is engaged with the gear 360, and the gear 360 passes through the gear assisting device 320 and the rail of the rail mechanism 100. 110 connections.
  • the rotary connector 310 and reverse directions to drive a motor 370 and the worm wheel 350 is rotated, the worm wheel 350 can be rotated forward and reverse direction, because the worm 350 meshed with the gear 360, worm gear 350 drives the gear 360 so that movement is occurring
  • the movement of the gear 360 drives the guide rail through the gear assist device O 110 can be used for repeated swings.
  • a raster switching operation is performed.
  • the needle cartridge 210 carried by the guide rail 110 is swung to a position below the base 340, and the guide rail 110 is swung to the right side of the base 340. At the upper end, another raster switching operation is performed, and so on.
  • the drive mechanism 3QQ drives the guide rail 110 to transport the needle cartridge 210 to the needle loading device or the needle withdrawal device, and controls the needle loading device 230 or the needle withdrawal device 240 to correspond to the needle cartridge 210 according to the three-dimensional shape of the object to be irradiated.
  • a tungsten needle of a corresponding specification is installed in the pinhole chamber 212 to form a tungsten alloy three-dimensional layer conforming to the three-dimensional shape of the object to be irradiated (as shown in FIGS. 7 and 8);
  • the grating mechanism 200 of the direct-compensated honeycomb array intensity-modulated grating system 10 of the present invention adopts a T-honey type needle magazine and cooperates with a variety of tungsten needles to selectively attach to the corresponding pinhole chamber 212.
  • Set tungsten needles of different specifications to achieve the purpose of shape and strength adjustment.
  • the finer the pinhole chamber 212 the higher the accuracy of the conformal adjustment, and the more the tungsten needle is provided, the higher the accuracy of the dose intensity adjustment.
  • the driving mechanism 300 of the direct-compensation honeycomb array intensity-modulating grating system 10 of the present invention transmits the driving force in the forward and reverse directions to the guide rail 110 when the motor 310 rotates in the forward and reverse directions by the cooperation between the worm wheel 350 and the gear 360, so that the guide rail
  • the shifting and transporting of the needle magazine 210 is performed on the base 340 of the 110, so that the present invention has a higher needle bin 210 switching and transport efficiency.
  • the grating mechanism of the direct-compensated decay honeycomb array intensity-modulating grating system can be composed of a plurality of needle magazines used in combination, that is, at least two layers of needle magazines of different specifications are superimposed and used, and the needle magazines of the respective layers are located at corresponding positions.
  • the pinhole chambers are connected to each other, and each layer of the needle magazine corresponds to a tungsten needle of a specification. In general, the more layers the needle cartridge is superimposed, the higher the accuracy of the intensity of the formed grating.
  • the direct-compensated decay honeycomb array intensity-modulating grating system 10 has four layers of needle-barrels of different specifications and is matched with four different specifications of tungsten needle structures, and this structure forms sixteen kinds in actual radiation therapy. Beams of different intensities.
  • the specific structure of the direct-compensated decay honeycomb array intensity-modulating grating system 10 is as follows:
  • the rail mechanism 100 of the direct-compensation honeycomb array intensity-modulating grating system 10 has four layers of guide rails 120, 130, 140, and 150 of different specifications.
  • the four-layer guide rails 120, 1 30, 140, and 150 are all annular and are disposed to overlap each other in the radial direction from the outside to the inside.
  • Four-layer rails 120, 1 30, 140, 150 The thicknesses in the radial direction are different from each other, and the needle chambers 121, 131, 141, 151 are sequentially opened thereon.
  • the rail mechanism 100 also has an arcuate slider 160.
  • the slider 160 is disposed on the outer side of the guide rail 120, and the slider 160 defines an opening 161 corresponding to the needle chamber 121.
  • the grating mechanism 200 includes four types of tungsten needles 221, 222, 223, 224, a needle loading device 230, a needle removing device 240, and four types of needle magazines 250, 260, 270. , 280.
  • the needle cartridges 250, 260, 270, 280 have a similar structure to the needle cartridge 210 of the first embodiment, and the needle cartridges 250, 260, 270, 280 are respectively mounted in the needle chambers 121, 131, 141, 151, and the needle cartridges
  • a plurality of pinhole chambers 252, 262, 272, 282 are formed on each of 250, 260, 270, and 280, respectively.
  • the needles 221, 222, 223 and 224 are detachably mounted in their matching pinhole chambers 252, 262, 272, 282.
  • the needle loading device 230 and the needle withdrawal device 240 are disposed on the outer side of the guide rail 250 and the inner side of the guide rail 280, respectively.
  • the driving mechanism 400 includes motors 411, 412, 413, 414, 415, a board 421, a cover 422, and a slide device 431, 432, 433, 434, 435, 436, 437, 438.
  • the plate 421 has a circular plate shape, and the plate 421 is provided with slide devices 435, 436, 437, and 438.
  • the cover plate 422 is disposed at a predetermined distance above the plate 421, and the slide plate device is disposed under the cover plate 422.
  • the slide devices 431, 432, 433, and 434 corresponding to 435, 436, 437, and 438.
  • Rails 431, 432, 433, 434 are respectively provided with guide rails between respective slide guides 435, 436, 437, 438
  • the slider 160 is mounted between the board 411 and the cover 412. Motors 411, 412, 413, 414, 415 are coupled to rack and pinion drives 441, 442, 443, 444, 445, respectively. Rack and pinion drives 441, 442, 443, 444, 445 are in turn coupled to rails 120, 130, 140, 150 and slider 160, respectively.
  • the rack and pinion drives 441, 442, 443, 444, 445 described above each have a rack and a gear.
  • Each of the racks is disposed at a lower portion of the guide rails 120, 130, 140, 150, and the gears are respectively mounted on the motors 411, 412, 413, 414, and 415, and the gears mesh with the corresponding racks.
  • a motor storage space is opened on the board 411, and the motors 411, 412, 413, 414, and 415 are disposed in the motor storage space.
  • the slider 160 of the present invention serves as an auxiliary mechanism for temporarily storing the needle magazine or assisting in the operation of the crochet or the tungsten needle.
  • the driving mechanism 400 independently drives the respective guide rails 120, 130, 140, 150 to respectively transport the corresponding needle magazines 250, 260, 270, 280 carried by the guide rails to the needle loading device or the needle withdrawal device, according to the irradiated object a three-dimensional shape, the control needle loading device 230 or the needle withdrawal device 240 performs a tungsten needle or a tungsten-retracting needle operation in the pinhole chambers 252, 262, 272, and 282 of each of the needle magazines 250, 260, 270, and 280;
  • the driving mechanism 400 independently drives the respective guide rails 120, 13G, '14G, 150 to transport the needle magazines 250, 260, 270, 280 each having the tungsten needles to a designated position, and each of the needle magazines 250, 260, 270 280 is overlapped, and the tungsten needles in the respective needle magazines 250, 260, 270, and 280 are formed to form a tungsten alloy three-dimensional layer conforming to the three-dimensional shape of the object to be irradiated, as shown in FIGS. 15 and 16.
  • the direct decay decay honeycomb array intensity modulation grating system 10 provided by the second embodiment of the present invention adopts a structure in which a plurality of needle magazines are superimposed and matched with the matching needles, so that the invention is easy to operate and more efficient in practical use. .
  • the four-layer needle magazines 250, 260, 270, and 280 cooperate with four types of tungsten needles 221, 222, 223, and 224 to provide sixteen different intensity illumination lines. The purpose of intensity adjustment.
  • a ray intensity of a needle magazine 280 of a needle magazine 270 of a needle magazine 260 of the needle cartridge 250 corresponds to a needle hole corresponding to a pinhole corresponding pinhole corresponding pinhole level is not loaded / 0 is not loaded / 0 is not loaded / 0 No needle / 0 0000 No needle / 0 No needle / 0 No needle / 0 Needle eight 0001 No needle / 0 No needle / 0 Needle / 1 No needle / 0 0010 No needle / 0 No needle / 0 Needle / 1 Needle / 1 0011 No needle / 0 Needle 8 No needle / 0 No needle / 0 0100 No needle / 0 Needle / 1 No needle / 0 Needle / 1 0101 No needle / 0 Needle / 1 Needle / 1 No needle / 0 0110 No needle / 0 Needle / 1 Needle / 1 Needle / 1 0111 Needle /
  • This embodiment is similar to the second embodiment except that the grating mechanism 200 has a four-set needle device 230' and four sets of needle-removing devices 240.
  • the four needle-setting devices 2 30 are disposed at equal intervals on the outer side of the guide rail.
  • the four sets of needle withdrawal devices 2 40 are disposed at equal intervals on the inner side of the guide rail 150, and the four sets of needle withdrawal devices 240 are located at the same angle as the four needle set devices 230.
  • the four-layer annular guide rails 120, 130, 140, and 150 are mutually non-interferingly rotated to drive the needle cartridges 250, 260, 270, 280 mounted on the guide rails 120, 130, 140, 150, respectively, to corresponding needle means mounted angle of 230, and back needle apparatus 240, and installed by a respective needle means 230 'are each needle cartridge 250, 260, 270, 280 or tungsten needle is mounted by a respective back needle apparatus 240, The tungsten needles are withdrawn from the respective needle magazines 250, 260, 270, and 280, respectively.
  • the four needle bins 250, 260, 270 of the direct-compensation honeycomb array intensity-modulating grating system 10 are directly
  • the 280 cooperates with the four set needle device 230, and the four sets of the needle removing device 240, so that the distribution of the needles in each needle magazine can be conveniently adjusted, thereby achieving the purpose of the it shape adjustment.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

Un système en réseau à intensité modulée conçu pour compenser la désintégration d'un réseau de en nid d'abeille utilisé en radiothérapie comprend un mécanisme de rail de guidage (100), un mécanisme de réseau (200) fixé sur le mécanisme de rail de guidage (100) et un mécanisme d'entraînement (300) conçu pour entraîner le mécanisme de rail de guidage (100). Le mécanisme de rail de guidage (100) comprend un rail de guidage (110). Le mécanisme en réseau comprend un compartiment à aiguilles comprenant de nombreuses aiguilles de tungstène (221, 222, 223, 224) de différentes dimensions. Le compartiment à aiguilles est fixé sur le rail de guidage (110). Plusieurs orifices à aiguilles sont situées dans le compartiment à aiguilles (210). Les aiguilles de tungstène (221, 222, 223, 224) de différentes dimensions peuvent être disposées séparément dans les orifices à aiguilles selon la forme de l'objet d'irradiation. Le système en réseau utilisé en radiothérapie possédant un compartiment à aiguilles en nid d'abeille et de nombreuses aiguilles en tungstène de différentes dimensions peut s'adapter et se moduler en intensité par l'installation d'aiguilles en tungstène de différentes spécifications dans les orifices à aiguilles correspondants.
PCT/CN2006/002497 2006-09-22 2006-09-22 Système en réseau à intensité modulée conçu pour compenser la désintégration d'un réseau en nid d'abeille et procédé d'utilisation associé WO2008043196A1 (fr)

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PCT/CN2006/002497 WO2008043196A1 (fr) 2006-09-22 2006-09-22 Système en réseau à intensité modulée conçu pour compenser la désintégration d'un réseau en nid d'abeille et procédé d'utilisation associé

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PCT/CN2006/002497 WO2008043196A1 (fr) 2006-09-22 2006-09-22 Système en réseau à intensité modulée conçu pour compenser la désintégration d'un réseau en nid d'abeille et procédé d'utilisation associé

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2595309A (en) * 2020-05-22 2021-11-24 Elekta ltd A radiotherapy device for modulating the intensity of radiation

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4780898A (en) * 1986-04-30 1988-10-25 Elekta Instrument Arrangement in a gamma unit
US5448611A (en) * 1992-08-04 1995-09-05 Framatome Societe Anonyme Process and apparatus for the treatment of lesions by high frequency radiation
US5627870A (en) * 1993-06-07 1997-05-06 Atea, Societe Atlantique De Techniques Avancees Device for treating cerebral lesions by gamma radiation, and corresponding treatment apparatus
CN1275410A (zh) * 1999-05-31 2000-12-06 深圳奥沃国际科技发展有限公司 多源放射线全身治疗装置
CN1310029A (zh) * 2001-02-28 2001-08-29 王增开 一种实现对x线适形调强的方法及其准直装置
US6512813B1 (en) * 1999-05-03 2003-01-28 Franz Krispel Rotating stereotactic treatment system
CN1810320A (zh) * 2005-01-28 2006-08-02 惠小兵 一种放射治疗装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4780898A (en) * 1986-04-30 1988-10-25 Elekta Instrument Arrangement in a gamma unit
US5448611A (en) * 1992-08-04 1995-09-05 Framatome Societe Anonyme Process and apparatus for the treatment of lesions by high frequency radiation
US5627870A (en) * 1993-06-07 1997-05-06 Atea, Societe Atlantique De Techniques Avancees Device for treating cerebral lesions by gamma radiation, and corresponding treatment apparatus
US6512813B1 (en) * 1999-05-03 2003-01-28 Franz Krispel Rotating stereotactic treatment system
CN1275410A (zh) * 1999-05-31 2000-12-06 深圳奥沃国际科技发展有限公司 多源放射线全身治疗装置
CN1310029A (zh) * 2001-02-28 2001-08-29 王增开 一种实现对x线适形调强的方法及其准直装置
CN1810320A (zh) * 2005-01-28 2006-08-02 惠小兵 一种放射治疗装置

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2595309A (en) * 2020-05-22 2021-11-24 Elekta ltd A radiotherapy device for modulating the intensity of radiation
GB2595309B (en) * 2020-05-22 2023-11-15 Elekta ltd A radiotherapy device for modulating the intensity of radiation

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