WO2008031780A3 - Method for producing fine-particle dispersions - Google Patents

Method for producing fine-particle dispersions Download PDF

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Publication number
WO2008031780A3
WO2008031780A3 PCT/EP2007/059436 EP2007059436W WO2008031780A3 WO 2008031780 A3 WO2008031780 A3 WO 2008031780A3 EP 2007059436 W EP2007059436 W EP 2007059436W WO 2008031780 A3 WO2008031780 A3 WO 2008031780A3
Authority
WO
WIPO (PCT)
Prior art keywords
medium
producing fine
particle dispersions
chemical compound
volume
Prior art date
Application number
PCT/EP2007/059436
Other languages
German (de)
French (fr)
Other versions
WO2008031780A2 (en
Inventor
Sebastian Koltzenburg
Bernd Bechtloff
Gelder Richard Van
Dirk Franke
Original Assignee
Basf Se
Sebastian Koltzenburg
Bernd Bechtloff
Gelder Richard Van
Dirk Franke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se, Sebastian Koltzenburg, Bernd Bechtloff, Gelder Richard Van, Dirk Franke filed Critical Basf Se
Publication of WO2008031780A2 publication Critical patent/WO2008031780A2/en
Publication of WO2008031780A3 publication Critical patent/WO2008031780A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Colloid Chemistry (AREA)

Abstract

The invention relates to a method for producing fine-particle dispersions of a chemical compound which is poorly soluble in a dispersant, by the turbulent intermixing of at least two liquid flows described as medium A and medium B, of which at least the liquid flow described as medium A contains the chemical compound to be dispersed or a precursor thereof, in a mixing device provided with at least two inlets and an outlet. The liquid flows are supplied in such a way that the angle between the longitudinal axes of a volume flow of medium A and a volume flow of medium B is between 10° and 170°, and the volume flows have different surface cross-sections.
PCT/EP2007/059436 2006-09-13 2007-09-10 Method for producing fine-particle dispersions WO2008031780A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06120565.4 2006-09-13
EP06120565 2006-09-13

Publications (2)

Publication Number Publication Date
WO2008031780A2 WO2008031780A2 (en) 2008-03-20
WO2008031780A3 true WO2008031780A3 (en) 2008-06-26

Family

ID=39184159

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/059436 WO2008031780A2 (en) 2006-09-13 2007-09-10 Method for producing fine-particle dispersions

Country Status (1)

Country Link
WO (1) WO2008031780A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008001991A1 (en) 2007-07-06 2009-09-25 Basf Se Use of homo and copolymers that comprise at least 10% by weight of a monomer selected from acrylic and methacrylic acid and up to 90% of one or more non-ionic monomers, where the sum of both is at least 70% of the monomers; composition and preparation of the active principle; aqueous dispersion and its preparation.
DE102009009060B3 (en) * 2009-02-16 2010-05-12 Karlsruher Institut für Technologie Process for the preparation of a dispersion and device for this purpose
DE102016108872A1 (en) * 2016-05-13 2017-11-30 Karlsruher Institut für Technologie Apparatus and method for carrying out precipitation reactions involving at least two starting materials

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020197282A1 (en) * 1999-02-23 2002-12-26 Mohseni Saeed H. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
US20030091649A1 (en) * 1995-06-07 2003-05-15 Bomberger David C. ICAM-1 formulation having controlled-size microparticles
US20050158386A1 (en) * 2001-09-05 2005-07-21 Shin-Etsu Chemical Co., Ltd. Process for producing a pharmaceutical solid preparation containing a poorly soluble drug
EP1688169A1 (en) * 2003-11-28 2006-08-09 Mitsubishi Chemical Corporation Method for producing fine organic compound particles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030091649A1 (en) * 1995-06-07 2003-05-15 Bomberger David C. ICAM-1 formulation having controlled-size microparticles
US20020197282A1 (en) * 1999-02-23 2002-12-26 Mohseni Saeed H. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
US20050158386A1 (en) * 2001-09-05 2005-07-21 Shin-Etsu Chemical Co., Ltd. Process for producing a pharmaceutical solid preparation containing a poorly soluble drug
EP1688169A1 (en) * 2003-11-28 2006-08-09 Mitsubishi Chemical Corporation Method for producing fine organic compound particles

Also Published As

Publication number Publication date
WO2008031780A2 (en) 2008-03-20

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