WO2008029148A3 - Cartilage repair - Google Patents

Cartilage repair Download PDF

Info

Publication number
WO2008029148A3
WO2008029148A3 PCT/GB2007/003367 GB2007003367W WO2008029148A3 WO 2008029148 A3 WO2008029148 A3 WO 2008029148A3 GB 2007003367 W GB2007003367 W GB 2007003367W WO 2008029148 A3 WO2008029148 A3 WO 2008029148A3
Authority
WO
WIPO (PCT)
Prior art keywords
cartilage repair
cell population
population
isolating
retention
Prior art date
Application number
PCT/GB2007/003367
Other languages
French (fr)
Other versions
WO2008029148A2 (en
Inventor
Charles William Archer
Samantha Nichola Haven
Sarah Frances Oldfield
Ilyas Mahmood Khan
Original Assignee
Univ Cardiff
Charles William Archer
Samantha Nichola Haven
Sarah Frances Oldfield
Ilyas Mahmood Khan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cardiff, Charles William Archer, Samantha Nichola Haven, Sarah Frances Oldfield, Ilyas Mahmood Khan filed Critical Univ Cardiff
Publication of WO2008029148A2 publication Critical patent/WO2008029148A2/en
Publication of WO2008029148A3 publication Critical patent/WO2008029148A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus

Abstract

The invention relates to a method for isolating a stable articular cartilage cell population wherein the cells of the population are characterised by the retention of their pericellular matrix. Further the invention concerns the use of the cell population in tissue repair.
PCT/GB2007/003367 2006-09-09 2007-09-07 Cartilage repair WO2008029148A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0617777.8 2006-09-09
GB0617777A GB0617777D0 (en) 2006-09-09 2006-09-09 Cartilage repair

Publications (2)

Publication Number Publication Date
WO2008029148A2 WO2008029148A2 (en) 2008-03-13
WO2008029148A3 true WO2008029148A3 (en) 2009-02-26

Family

ID=37232667

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/003367 WO2008029148A2 (en) 2006-09-09 2007-09-07 Cartilage repair

Country Status (2)

Country Link
GB (1) GB0617777D0 (en)
WO (1) WO2008029148A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001029189A2 (en) * 1999-10-15 2001-04-26 Mount Sinai Hospital Synthetic substrate for tissue formation
WO2003092542A2 (en) * 2002-05-01 2003-11-13 Verigen Ag Injectable chondrocyte implant
US20040142465A1 (en) * 1998-12-21 2004-07-22 Fidia Advanced Biopolymers, S.R.L. Injectable hyaluronic acid derivative with pharmaceuticals/cells
EP1576957A1 (en) * 2004-03-18 2005-09-21 Universiteit Twente Tissue repair using pluripotent cells
WO2006050213A2 (en) * 2004-10-29 2006-05-11 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
EP1894581A1 (en) * 2006-08-31 2008-03-05 CellCoTec B.V. Repair of cartilage tissue using a matrix gel containing chondrocytes

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142465A1 (en) * 1998-12-21 2004-07-22 Fidia Advanced Biopolymers, S.R.L. Injectable hyaluronic acid derivative with pharmaceuticals/cells
WO2001029189A2 (en) * 1999-10-15 2001-04-26 Mount Sinai Hospital Synthetic substrate for tissue formation
WO2003092542A2 (en) * 2002-05-01 2003-11-13 Verigen Ag Injectable chondrocyte implant
EP1576957A1 (en) * 2004-03-18 2005-09-21 Universiteit Twente Tissue repair using pluripotent cells
WO2006050213A2 (en) * 2004-10-29 2006-05-11 Michalow Alexander E Methods of promoting healing of cartilage defects and method of causing stem cells to differentiate by the articular chondrocyte pathway
EP1894581A1 (en) * 2006-08-31 2008-03-05 CellCoTec B.V. Repair of cartilage tissue using a matrix gel containing chondrocytes

Also Published As

Publication number Publication date
GB0617777D0 (en) 2006-10-18
WO2008029148A2 (en) 2008-03-13

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