WO2008021212A2 - High speed swelling, pressure exerting hemostatic device - Google Patents

High speed swelling, pressure exerting hemostatic device Download PDF

Info

Publication number
WO2008021212A2
WO2008021212A2 PCT/US2007/017753 US2007017753W WO2008021212A2 WO 2008021212 A2 WO2008021212 A2 WO 2008021212A2 US 2007017753 W US2007017753 W US 2007017753W WO 2008021212 A2 WO2008021212 A2 WO 2008021212A2
Authority
WO
WIPO (PCT)
Prior art keywords
polymer particles
hemostatic
porous membrane
membrane
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/017753
Other languages
English (en)
French (fr)
Other versions
WO2008021212A3 (en
Inventor
Javier De Luis
Marco Serra
Timothy Sutherland
Liping Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Payload Systems Inc
Original Assignee
Payload Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Payload Systems Inc filed Critical Payload Systems Inc
Priority to EP07811231A priority Critical patent/EP2063920A2/en
Priority to JP2009523851A priority patent/JP2010500116A/ja
Priority to CA2695526A priority patent/CA2695526A1/en
Priority to AU2007284665A priority patent/AU2007284665A1/en
Publication of WO2008021212A2 publication Critical patent/WO2008021212A2/en
Publication of WO2008021212A3 publication Critical patent/WO2008021212A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/01—Non-adhesive bandages or dressings
    • A61F13/01008—Non-adhesive bandages or dressings characterised by the material
    • A61F13/01017—Non-adhesive bandages or dressings characterised by the material synthetic, e.g. polymer based
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/01—Non-adhesive bandages or dressings
    • A61F13/01021—Non-adhesive bandages or dressings characterised by the structure of the dressing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/01—Non-adhesive bandages or dressings
    • A61F13/01034—Non-adhesive bandages or dressings characterised by a property
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/01—Non-adhesive bandages or dressings
    • A61F13/01034—Non-adhesive bandages or dressings characterised by a property
    • A61F13/01038—Flexibility, stretchability or elasticity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A61F2013/00472—Plasters use haemostatic with chemical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/0054—Plasters use for deep wounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/00659—Plasters adhesive polymeric base
    • A61F2013/00663—Plasters adhesive polymeric base acrylic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/00685—Plasters adhesive soluble in liquid, e.g. of particular pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Definitions

  • Hemostatic device 10 comprises a first membrane 12, a second membrane 14, and absorbent material 16 contained between the membranes 12 and 14.
  • Material 16 may comprise a blend of superabsorbent polymer particles 1 1 and wicking elements, such as wicking fibers 13, and may further include other fibrous fillers.
  • the wicking material may reduce coagulation of blood on the outer surface 15 of the device, which can reduce premature gelling and promote transport of fluid (e.g., blood fluids) past the outer surface 15 of hemostatic device 10 and into absorbent material 16.
  • Membranes 12 and 14 may be joined along their outer edges to form a seal 18 by gluing, sewing, heat sealing, or any other suitable sealing method known to those skilled in the art.
  • the hemostatic device 40 can be folded as required to have a similar effect as, for example, the insertion of multiple smaller hemostatic devices, or can simply be laid over a wound opening and then pushed in to ensure contact all around the wound surface with excess device material simply protruding from the wound.
  • the sealing borders between individual hemostatic units may comprise perforations to act as a tear-off device, allowing the device size to be tailored as needed.
  • a hemostatic device 50 may comprise a plurality of hemostatic units 52, wherein each hemostatic unit comprises at least one porous membrane forming an enclosure that has an interior containing absorbent polymer particles.
  • Membranes suitable for use in the present invention may also contain pores or other openings through the membrane to facilitate more rapid passage of fluid through the membrane.
  • a wide variety of suitable membrane materials having a wide variety of average pore size and pore size distribution are readily commercially available from a number of suppliers.
  • the pores of the membrane may be sufficiently small to contain the polymer, or polymer and wicking fiber mixture, without leakage, while sufficiently large to enable free fluid flow.
  • the membrane may possess pores large enough to enable the uninhibited flow of blood.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
PCT/US2007/017753 2006-08-11 2007-08-10 High speed swelling, pressure exerting hemostatic device Ceased WO2008021212A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP07811231A EP2063920A2 (en) 2006-08-11 2007-08-10 High speed swelling, pressure exerting hemostatic device
JP2009523851A JP2010500116A (ja) 2006-08-11 2007-08-10 高速で膨潤して圧力を加える止血デバイス
CA2695526A CA2695526A1 (en) 2006-08-11 2007-08-10 High speed swelling, pressure exerting hemostatic device
AU2007284665A AU2007284665A1 (en) 2006-08-11 2007-08-10 High speed swelling, pressure exerting hemostatic device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83739906P 2006-08-11 2006-08-11
US60/837,399 2006-08-11

Publications (2)

Publication Number Publication Date
WO2008021212A2 true WO2008021212A2 (en) 2008-02-21
WO2008021212A3 WO2008021212A3 (en) 2008-10-02

Family

ID=38667143

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/017753 Ceased WO2008021212A2 (en) 2006-08-11 2007-08-10 High speed swelling, pressure exerting hemostatic device

Country Status (7)

Country Link
US (2) US7838716B2 (enExample)
EP (1) EP2063920A2 (enExample)
JP (1) JP2010500116A (enExample)
AU (1) AU2007284665A1 (enExample)
CA (1) CA2695526A1 (enExample)
WO (1) WO2008021212A2 (enExample)
ZA (1) ZA200901707B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2468905A (en) * 2009-03-27 2010-09-29 Brightwake Ltd Wound packing element
WO2011077145A1 (en) * 2009-12-21 2011-06-30 Smith & Nephew Plc Hemostatic device for administration to a wound cavity

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GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
GB0325129D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus in situ
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
ES2715605T3 (es) 2007-11-21 2019-06-05 Smith & Nephew Apósito para heridas
JP5613566B2 (ja) 2007-11-21 2014-10-22 スミス アンド ネフュー ピーエルシーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ 創傷被覆材
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
US8852558B2 (en) * 2008-03-11 2014-10-07 Materials Modification, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst
US8828358B2 (en) * 2008-03-11 2014-09-09 Materials Modifications, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide
MX2010013068A (es) 2008-05-30 2010-12-21 Kci Licensing Inc Soportes y sistemas de compresion de presion reducida para el cierre de heridas lineales.
MX2010013133A (es) 2008-05-30 2010-12-20 Kci Licensing Inc Dispositivos de aposito para el tratamiento de heridas utilizando presion reducida.
US20100280428A1 (en) * 2009-04-25 2010-11-04 Widgerow Alan D Medical device for shrinking open wounds
CA2760201C (en) * 2009-05-04 2019-11-19 Oregon Biomedical Engineering Institute, Inc. Hemorrhage control devices and methods
CA2770182C (en) * 2009-08-05 2016-09-27 Tyco Healthcare Group Lp Surgical wound dressing incorporating connected hydrogel beads having an embedded electrode therein and related methods therefor
US20110237994A1 (en) * 2010-03-25 2011-09-29 Combat Medical Systems, Llc Void-filling wound dressing
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
US20120209232A1 (en) 2011-02-16 2012-08-16 Andrew Barofsky Wound stasis dressing for large surface wounds
US9623223B2 (en) 2011-02-16 2017-04-18 Revmedx, Inc. Wound dressings comprising a plurality of liquid-expandable articles
AU2012295120A1 (en) 2011-08-14 2014-02-27 Materials Modification, Inc. Method and composition for in situ formation of an artificial blockage to control blood loss
US8993831B2 (en) * 2011-11-01 2015-03-31 Arsenal Medical, Inc. Foam and delivery system for treatment of postpartum hemorrhage
US20160175157A1 (en) * 2014-12-22 2016-06-23 Terence W. Kolb Impregnable and Expanding Wound Packing Article
EP3248578A1 (en) * 2016-05-24 2017-11-29 Biocer-Entwicklungs-GmbH Unit for hemostasis and arrangement containing the same
CN107252335B (zh) * 2017-06-28 2023-02-28 王洛 止血装置及用于推送该止血装置的注射器
US20200182526A1 (en) * 2017-08-24 2020-06-11 Arctic Express Packs LLC Cold packs system
GB202310268D0 (en) * 2023-07-05 2023-08-16 Smith & Nephew Negative pressure wound therapy devices and methods utilizing a wound filler

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2468905A (en) * 2009-03-27 2010-09-29 Brightwake Ltd Wound packing element
GB2468905B (en) * 2009-03-27 2013-12-11 Brightwake Ltd Wound packing material
WO2011077145A1 (en) * 2009-12-21 2011-06-30 Smith & Nephew Plc Hemostatic device for administration to a wound cavity

Also Published As

Publication number Publication date
EP2063920A2 (en) 2009-06-03
US20110270300A1 (en) 2011-11-03
AU2007284665A1 (en) 2008-02-21
US7838716B2 (en) 2010-11-23
WO2008021212A3 (en) 2008-10-02
CA2695526A1 (en) 2008-02-21
US8395010B2 (en) 2013-03-12
JP2010500116A (ja) 2010-01-07
ZA200901707B (en) 2010-06-30
US20080071207A1 (en) 2008-03-20

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