WO2008017884A3 - Vapour generator - Google Patents

Vapour generator Download PDF

Info

Publication number
WO2008017884A3
WO2008017884A3 PCT/GB2007/050474 GB2007050474W WO2008017884A3 WO 2008017884 A3 WO2008017884 A3 WO 2008017884A3 GB 2007050474 W GB2007050474 W GB 2007050474W WO 2008017884 A3 WO2008017884 A3 WO 2008017884A3
Authority
WO
WIPO (PCT)
Prior art keywords
gas
vapour generator
sample
permeation
flow
Prior art date
Application number
PCT/GB2007/050474
Other languages
French (fr)
Other versions
WO2008017884A2 (en
Inventor
Russell Parris
Original Assignee
Owlstone Ltd
Russell Parris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Owlstone Ltd, Russell Parris filed Critical Owlstone Ltd
Publication of WO2008017884A2 publication Critical patent/WO2008017884A2/en
Publication of WO2008017884A3 publication Critical patent/WO2008017884A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N2001/2893—Preparing calibration standards

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

A vapour generator is described, including a gas inlet, a sample permeation chamber, a sample flow outlet, and a split flow outlet. A gas flow path is defined from the inlet through the permeation chamber to the outlets. A valve or similar for splitting the gas flow is located after the sample permeation chamber. This arrangement ensures that the flow rate of gas passing the permeation source is constant, as is the concentration of analyte carried by the gas. Variation of the split flow to sample flow rate may be used to vary the concentration of analyte entering a measurement device coupled to the vapour generator, such as an ion mobility spectrometer. Also described is a method of manufacturing a permeation source for use in the vapour generator.
PCT/GB2007/050474 2006-08-08 2007-08-07 Vapour generator WO2008017884A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0615682.2 2006-08-08
GBGB0615682.2A GB0615682D0 (en) 2006-08-08 2006-08-08 Vapour generator

Publications (2)

Publication Number Publication Date
WO2008017884A2 WO2008017884A2 (en) 2008-02-14
WO2008017884A3 true WO2008017884A3 (en) 2008-05-02

Family

ID=37027376

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/050474 WO2008017884A2 (en) 2006-08-08 2007-08-07 Vapour generator

Country Status (2)

Country Link
GB (1) GB0615682D0 (en)
WO (1) WO2008017884A2 (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3776023A (en) * 1971-12-22 1973-12-04 Monitor Labs Inc Calibration system for gas analyzers
US4531398A (en) * 1982-07-27 1985-07-30 Association pour la Recherche et le Develloppement des Methodes et Processus Industriels-A.R.M.I.N.E.S. Calibration system for gas analyzers
US5312756A (en) * 1991-07-15 1994-05-17 Umpqua Research Company Total organic carbon (TOC) and total inorganic carbon (TIC) calibration system
US5324478A (en) * 1987-08-14 1994-06-28 American Air Liquide Gas generating apparatus
CA2119113A1 (en) * 1994-03-15 1995-09-16 Frank H. Schaedlich Method and Apparatus for Detecting Mercury
DE10157728A1 (en) * 2001-11-24 2003-06-12 Forschungszentrum Juelich Gmbh Diffusion vessel, e.g. for calibration of gas chromatography analyzer, has one-piece supply vessel and diffusion capillary made of same chemically inert material, to give defined diffusion rate of highly reactive substances
US20040216508A1 (en) * 2003-02-14 2004-11-04 Hirsch Jeffrey A. Permeation calibrator

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3776023A (en) * 1971-12-22 1973-12-04 Monitor Labs Inc Calibration system for gas analyzers
US4531398A (en) * 1982-07-27 1985-07-30 Association pour la Recherche et le Develloppement des Methodes et Processus Industriels-A.R.M.I.N.E.S. Calibration system for gas analyzers
US5324478A (en) * 1987-08-14 1994-06-28 American Air Liquide Gas generating apparatus
US5312756A (en) * 1991-07-15 1994-05-17 Umpqua Research Company Total organic carbon (TOC) and total inorganic carbon (TIC) calibration system
CA2119113A1 (en) * 1994-03-15 1995-09-16 Frank H. Schaedlich Method and Apparatus for Detecting Mercury
DE10157728A1 (en) * 2001-11-24 2003-06-12 Forschungszentrum Juelich Gmbh Diffusion vessel, e.g. for calibration of gas chromatography analyzer, has one-piece supply vessel and diffusion capillary made of same chemically inert material, to give defined diffusion rate of highly reactive substances
US20040216508A1 (en) * 2003-02-14 2004-11-04 Hirsch Jeffrey A. Permeation calibrator

Also Published As

Publication number Publication date
GB0615682D0 (en) 2006-09-13
WO2008017884A2 (en) 2008-02-14

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