WO2007141718A3 - Method and apparatus for providing samples of volatiles to analysis using a multi-port valve and cryo-modulation - Google Patents

Method and apparatus for providing samples of volatiles to analysis using a multi-port valve and cryo-modulation Download PDF

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Publication number
WO2007141718A3
WO2007141718A3 PCT/IB2007/052063 IB2007052063W WO2007141718A3 WO 2007141718 A3 WO2007141718 A3 WO 2007141718A3 IB 2007052063 W IB2007052063 W IB 2007052063W WO 2007141718 A3 WO2007141718 A3 WO 2007141718A3
Authority
WO
WIPO (PCT)
Prior art keywords
volatiles
cryo
modulation
analysis
port valve
Prior art date
Application number
PCT/IB2007/052063
Other languages
French (fr)
Other versions
WO2007141718A2 (en
Inventor
Olivier Haefliger
Original Assignee
Firmenich & Cie
Olivier Haefliger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie, Olivier Haefliger filed Critical Firmenich & Cie
Priority to EP07736065A priority Critical patent/EP2032965A2/en
Publication of WO2007141718A2 publication Critical patent/WO2007141718A2/en
Publication of WO2007141718A3 publication Critical patent/WO2007141718A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2226—Sampling from a closed space, e.g. food package, head space
    • G01N2001/2229—Headspace sampling, i.e. vapour over liquid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/201—Injection using a sampling valve multiport valves, i.e. having more than two ports
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/202—Injection using a sampling valve rotary valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/207—Injection using a sampling valve with metering cavity, e.g. sample loop
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The present invention is related to a sampling technique for volatiles and its use to concentrate and/or detect and/or separate chemical components of complex mixtures thereof that enable the automatic on-line sampling and real-time analysis of volatiles present at low concentrations, for example in the headspace. The method and apparatus according to the invention comprise loading means equipped with a multiport-valve and mobile cryo-modulation means.
PCT/IB2007/052063 2006-06-09 2007-06-01 Method and apparatus for providing samples of volatiles to analysis using a multi-port valve and cryo-modulation WO2007141718A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07736065A EP2032965A2 (en) 2006-06-09 2007-06-01 Method and apparatus for on-line monitoring of volatiles to analysis using a multi-port valve and cryo-modulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IBPCT/IB2006/051848 2006-06-09
IB2006051848 2006-06-09

Publications (2)

Publication Number Publication Date
WO2007141718A2 WO2007141718A2 (en) 2007-12-13
WO2007141718A3 true WO2007141718A3 (en) 2008-02-14

Family

ID=38650087

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/052063 WO2007141718A2 (en) 2006-06-09 2007-06-01 Method and apparatus for providing samples of volatiles to analysis using a multi-port valve and cryo-modulation

Country Status (2)

Country Link
EP (1) EP2032965A2 (en)
WO (1) WO2007141718A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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WO2014143026A1 (en) * 2013-03-15 2014-09-18 The Regents Of The University Of California System and method for non- invasively and non- destructively authenticating bottled beverages
CN103344728B (en) * 2013-06-18 2014-10-15 华东师范大学 In-situ headspace sample injector
CN103604897B (en) * 2013-10-31 2014-12-03 陕西延长石油(集团)有限责任公司研究院 On-line multidimensional gas chromatographic analysis device universal for low carbon catalytic conversion reaction
CN104914198B (en) * 2014-03-11 2017-03-15 上海兰博贸易有限公司 Gas automatic sampling device and its using method
CN105784889B (en) * 2014-12-25 2018-11-30 中国科学院广州能源研究所 The quick analysis system and method for thick gas tar oil content
CN105891367B (en) * 2016-04-27 2018-06-15 中国烟草总公司郑州烟草研究院 A kind of gas-chromatography of essence spice for cigarette-quadrupole rod flight time mass spectrum/flame ion detection method
CN106226446B (en) * 2016-09-21 2018-01-30 贵州省环境科学研究设计院 A kind of gas-chromatography dilutes inlet duct
US10717056B1 (en) 2019-09-09 2020-07-21 Michael Cem Gokay Method and apparatus for purification of cannabinoid extracts
CN112113810A (en) * 2020-08-11 2020-12-22 中国原子能科学研究院 High-pressure oxidation treatment device for organic samples
CN112578728B (en) * 2020-12-15 2021-12-07 中国环境科学研究院 Switching device and method for switching gas of ICP spectrometer
CN114778717A (en) * 2022-03-28 2022-07-22 暨南大学 Online measurement method for biogenic volatile organic compounds

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4043202A (en) * 1976-03-19 1977-08-23 Sun Oil Company Of Pennsylvania Sample injection system for analyzers
WO2003102573A1 (en) * 2002-05-29 2003-12-11 Dani Instruments S.P.A. Method and device for partializing a gaseous sample in chromatographic introduction
EP1457774A1 (en) * 2003-03-11 2004-09-15 Hitachi High-Technologies Corporation Separation analyser
US20050053522A1 (en) * 2003-09-10 2005-03-10 King Mackenzie E. Sampling management for a process analysis tool to minimize sample usage and decrease sampling time
EP1536228A1 (en) * 2003-11-27 2005-06-01 Agilent Technologies, Inc. Dual loop autosampling
WO2005111599A1 (en) * 2004-05-17 2005-11-24 Firmenich Sa New multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4043202A (en) * 1976-03-19 1977-08-23 Sun Oil Company Of Pennsylvania Sample injection system for analyzers
WO2003102573A1 (en) * 2002-05-29 2003-12-11 Dani Instruments S.P.A. Method and device for partializing a gaseous sample in chromatographic introduction
EP1457774A1 (en) * 2003-03-11 2004-09-15 Hitachi High-Technologies Corporation Separation analyser
US20050053522A1 (en) * 2003-09-10 2005-03-10 King Mackenzie E. Sampling management for a process analysis tool to minimize sample usage and decrease sampling time
EP1536228A1 (en) * 2003-11-27 2005-06-01 Agilent Technologies, Inc. Dual loop autosampling
WO2005111599A1 (en) * 2004-05-17 2005-11-24 Firmenich Sa New multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GORECKI ET AL: "The evolution of comprehensive two-dimensional gas chromatography (GCxGC)", JOURNAL OF SEPARATION SCIENCE, WILEY VCH, WEINHEIM, DE, vol. 27, April 2004 (2004-04-01), pages 359 - 379, XP002337494, ISSN: 1615-9306 *
MARRIOTT P ET AL: "Cryogenic solute manipulation in gas chromatography - the longitudinal modulation approach", TRAC, TRENDS IN ANALYTICAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 18, no. 2, February 1999 (1999-02-01), pages 114 - 125, XP004155356, ISSN: 0165-9936 *
MARRIOTT P ET AL: "TARGETED MULTIDIMENSIONAL GAS CHROMATOGRAPHY USING MICROSWITCHING AND CRYOGENIC MODULATION", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 75, no. 20, 15 October 2003 (2003-10-15), pages 5532 - 5538, XP001186437, ISSN: 0003-2700 *

Also Published As

Publication number Publication date
WO2007141718A2 (en) 2007-12-13
EP2032965A2 (en) 2009-03-11

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