WO2008002773A2 - Ultrasound wound care device and method - Google Patents
Ultrasound wound care device and method Download PDFInfo
- Publication number
- WO2008002773A2 WO2008002773A2 PCT/US2007/071166 US2007071166W WO2008002773A2 WO 2008002773 A2 WO2008002773 A2 WO 2008002773A2 US 2007071166 W US2007071166 W US 2007071166W WO 2008002773 A2 WO2008002773 A2 WO 2008002773A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chamber
- coupling medium
- cavitation chamber
- ultrasound
- ultrasound waves
- Prior art date
Links
- 238000002604 ultrasonography Methods 0.000 title claims abstract description 99
- 238000000034 method Methods 0.000 title claims abstract description 30
- 230000008878 coupling Effects 0.000 claims abstract description 109
- 238000010168 coupling process Methods 0.000 claims abstract description 109
- 238000005859 coupling reaction Methods 0.000 claims abstract description 109
- 206010052428 Wound Diseases 0.000 claims abstract description 105
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 105
- 239000012530 fluid Substances 0.000 claims abstract description 10
- 238000000605 extraction Methods 0.000 claims description 42
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- 230000001225 therapeutic effect Effects 0.000 abstract description 6
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- 238000002560 therapeutic procedure Methods 0.000 description 12
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H1/00—Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
- A61M1/92—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing with liquid supply means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B2017/22005—Effects, e.g. on tissue
- A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
- A61B2017/22008—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/225—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves
- A61B17/2251—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves characterised by coupling elements between the apparatus, e.g. shock wave apparatus or locating means, and the patient, e.g. details of bags, pressure control of bag on patient
- A61B2017/2253—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves characterised by coupling elements between the apparatus, e.g. shock wave apparatus or locating means, and the patient, e.g. details of bags, pressure control of bag on patient using a coupling gel or liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
- A61M1/96—Suction control thereof
- A61M1/962—Suction control thereof having pumping means on the suction site, e.g. miniature pump on dressing or dressing capable of exerting suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0039—Ultrasound therapy using microbubbles
Definitions
- the present invention relates to a wound care device and method for providing therapeutic benefits directly and indirectly from the transmission of ultrasound through a coupling medium.
- Wounds encountered in clinical practice can be slow to heal and difficult to manage. Such wounds are often seen in diabetics, the elderly, individuals with comprised immune systems, and other at risk patient populations. The pain produced by such wounds disables the patient, thereby reducing the patient's quality of life. An unhealed wound's susceptibility to infection increases a patient's morbidity and mortality. Placing the patient in an environment abundant in drug resistant infectious agents, such as hospital or institutional settings, further increases the patient's morbidity and mortality. Treating such wounds, especially after a serious infection has set in, burdens healthcare providers by increasing the time and resources that must be devoted to a single patient.
- Topical negative pressure therapy applies a controlled negative pressure to the surface of the wound.
- the negative pressure is created by a vacuum pump or similar mechanism.
- Represented devices are encompassed in (Patent No. 7,004,915 to Boynton et al.; Patent No. 6,994,702 to Johnson; Patent No. 6,695,823 to Lina et al.; and Patent No. 6,135,116 to Vogel et al.).
- Topical negative pressure therapy devices have been shown to increase blood flow to the wound and the rate of granulation, or tissue growth, while decreasing the level of bacteria and inflammatory agents present.
- Topical negative pressure therapy however, have several limitations.
- topical negative pressure therapy devices are only capable of promoting healing in clean and debrided wound beds.
- negative pressure therapy is contraindicated over necrotic tissue (Jones et al. 2005), the presence of which can hinder or prevent healing.
- High rental costs and expensive silver dressings further limit the applicability of topical negative pressure devices in wound care. This is especially true in light of the fact that 4 to 6 weeks of continuous therapy is required, during which time the machine cannot be used on more than one patient.
- the dressings employed by such devices are porous by necessity. As the wound heals, new tissue grows into the porous openings of the dressing. When the dressing is removed, healed tissue is removed with it.
- ultrasonic wound care devices treat wounds by increasing blood flow to the wound.
- Represented devices are encompassed in (Patent No. 7,025,735 to Soring et al.; Patent No. 6,964,647 to Babaev; Patent No. 6,960,173 to Babaev; Patent No. 6,916,296 to Soring; Patent No. 6,761,729 to Babaev; Patent No. 6,723,064 to Babaev; Patent No. 6,663,554 to Babaev; Patent No. 6,623,444 to Babaev; Patent No. 6,601 ,581 to Babaev; Patent No.
- the present invention relates to a wound care device and method for providing therapeutic benefits directly and indirectly from the transmission of ultrasound through a coupling medium.
- the ultrasound wound care device comprises a generator, an ultrasound transducer, an ultrasound horn, and a cavitation chamber.
- the device may further comprise a fluid, non-atomized, coupling medium.
- Ultrasound entering the cavitation chamber induces cavitations within the coupling medium, providing therapeutic benefits to the wound being treated.
- the ultrasound entering the cavitation chamber is also transmitted through the coupling medium to the wound, providing direct therapeutic benefits to the wound.
- Ultrasonically inducing negative and positive pressure over the surface of a wound the present invention treats wounds and assists wound healing.
- the cavitation chamber located at the distal end of the ultrasound horn, contains an inner cavity, open at its base, capable of holding a fluid coupling medium.
- Ultrasonic energy emitted from the present invention induces cavitations within the coupling medium held in the cavitation chamber, leading to the formation of gas bubbles within the coupling medium. This phenomenon is similar to water boiling, but is not the result of heating the coupling medium.
- gas bubbles form and dissipate against the surface of the wound micro domains of topical positive and negative pressure are created over the wound's surface. The alternating pressure removes necrotic tissue and other contaminates from the wound.
- the coupling medium within the cavitation chamber is a fluid medium that carries the ultrasonic waves emitted from the present invention to the wound being treated.
- the coupling medium may be a liquid, gel, or similar fluid medium. Dissolving or suspending drugs within the coupling medium may be done to assist drug delivery during wound treatment. Liberating the dissolved or suspended drug from the coupling medium while inducing macro cavitations on the surface of the wound and micro cavitations along with micro streaming within the wound bed, the ultrasound waves transport the drug into and across the wound bed.
- the coupling medium is also capable of moistening the wound.
- ultrasound waves induce micro cavitation and microstreaming. Killing bacteria and other infectious agents, the induced micro cavitation disinfects the wound while cavitations within the coupling medium remove infectious agents from the wound.
- the delivered ultrasound waves increase blood flow to the wound bed, thereby allowing for the increased delivery of nutrients to the wound and the removal of inflammatory agents from the wound.
- the fluctuating topical pressure also helps to promote blood and nutrient flow to the wound bed and the removal of inflammatory agents. Producing overlapping healing benefits, the fluctuating topical pressure and delivered ultrasound waves exaggerate the actions of either when used alone, thereby creating a synergistic healing action.
- the healing action of the present invention may be furthered enhanced by providing a positive or negative pressure to the inner cavity of the cavitation chamber by feeding the coupling medium into the inner cavity with a pump or by extracting the coupling medium with a vacuum.
- Driving the coupling medium into the inner cavity of the cavitation chamber with a pump places a general positive pressure against the surface of the wound.
- extracting the coupling medium from the inner cavity of the cavitation chamber with a vacuum places a general negative pressure against the surface of the wound.
- the user of the device may control the general pressure within the inner cavity of the cavitation chamber and alternate the pressure from positive to negative or negative to positive during treatment.
- the present invention creates a synergistic combination of ultrasound and topical pressure wound therapy.
- Flowing coupling medium through the inner cavity of the cavitation chamber enables the user to flush out debris, necrotic tissue, bacteria, and other contaminants removed from the wound during treatment.
- Treating a wound with the present invention does not require continued use of the device until the wound is healed. Rather, the device is used intermittently to treat a patient's wound. After a patient has received a treatment session, the device can be cleaned and sterilized and then used to treat other patients.
- One aspect of the present invention may be to treat wounds and assist wound healing.
- Another aspect of the present invention may be to remove necrotic tissue, infectious agents, and other contaminants from the wound.
- Another aspect of the present invention may be to deliver drugs to the wound.
- Another aspect of the present invention may be to moisten the wound.
- Another aspect of the present invention may be to disinfect the wound by killing bacteria and other infectious agents.
- Another aspect of the present invention may be to increase the blood flow to the wound bed.
- Another aspect of the present invention may be to increase the delivery of nutrients to the wound.
- Another aspect of the present invention may be to remove inflammatory agents from the wound.
- Another aspect of the present invention may be to create microdomains of fluctuating pressure over the surface of the wound being treated.
- Another aspect of the present invention may be to provide topical pressure therapy.
- Another aspect of the present invention may be to alternate pressure from positive to negative or negative to positive during treatment.
- Another aspect of the present invention may be to create a synergistic relationship between ultrasound therapy and topical pressure therapy.
- Another aspect of the present invention may be to flush out debris, necrotic tissue, bacterial, and other contaminants from the wound.
- Another aspect of the present invention may be to allow for the simultaneous treatment of multiple patients with a single device.
- Figure 2 depicts a cross-sectional view of an alternative configuration of the present invention further comprising a feed channel.
- Figure 3 depicts a cross-sectional view of an alternative configuration of the present invention further comprising a feed channel and an extraction channel.
- Figure 4 depicts a cross-sectional view of an alternative configuration of the present invention further comprising an ultrasound tip and feed channel.
- Figure 5 depicts a cross-sectional view of an alternative configuration of the present invention further comprising an ultrasound tip, a feed channel, and an extraction channel.
- Figures 6a-6b depicts a system view and a cross-sectional view of a cavitation chamber for use with the present invention.
- Figure 7 depicts a cross-sectional view of an alternative configuration of the cavitation chamber comprising an accordion like base.
- Figures 8a-8b depicts a system view and a cross-sectional view of alternative mechanical means of attaching the cavitation chamber to the horn and/or tip.
- Figure 9 depicts an ultrasound tip for use with the present invention.
- Figures 10a-10d depicts cross-sectional views of various ultrasound tip configurations that may be used with the present invention.
- FIG. 1 Depicted in Figure 1 is the wound care device of the present invention.
- the device comprises a generator 1 connected to an ultrasound transducer 2, an ultrasound horn 3 located at the distal end of the transducer 2, and a cavitation chamber 4 at the distal end of horn 3.
- the horn 3 is located at the outer apex of the cavitation chamber 4.
- the outer apex of the cavitation chamber 4 refers to the region at or near the chamber's top.
- An ultrasound horn is located at the apex of the chamber if it transmits longitudinal ultrasound waves into the wound.
- the cavitation chamber 4 comprises an inner cavity 5 open at its base, capable of holding a fluid, non-atomized, coupling medium, not shown.
- the coupling medium held within the cavitation chamber may be a liquid, gel, or similar fluid medium. Although a coupling medium that fails to atomize when exposed to ultrasound waves is preferred, an atomized coupling medium may also be employed.
- the coupling medium may be a saline solution.
- the coupling medium may also be a solution containing drugs and/or other healing agents, such as, but not limited to, anticoagulants, anti-inflammatory agents, anti-viral agents, antibiotics, or vitamins. The drugs or other healing agents may be suspended and/or dissolved within the coupling medium.
- the cavitation chamber 4 may be integral with the horn 3 as to form a single part.
- the cavitation chamber 4 may be a separate piece attached to the horn 3 by mechanical or other means.
- the means of attaching the cavitation chamber 4 to horn 3 may be such as to allow the cavitation chamber 4 to be removed and replaced by the user.
- a removable cavitation chamber enables the user to adjust the size and/or configuration of the treatment area as to conform to the wound being treated.
- the horn 3 may be integral with the transducer 2 as to form a single part.
- the horn 3 may be separate piece, either alone or in combination with cavitation chamber 4, attached to the transducer 2 by mechanical or other means.
- the means of attaching the horn 3 to the transducer 2 may be such as to allow the horn to be removed and replaced by the user.
- a removable horn enables the user to adjust the parameters of the emitted ultrasound waves. In so doing, the user may configure the device to emit ultrasound waves that induce a desired type of cavitation within and/or better match the coupling medium chosen.
- a removable horn also enables the user to configure the device to emit ultrasound waves which are best suited to type of wound being treated.
- the ultrasound waves employed may vary with respect to frequency; approximately 15 kHz to 20 MHz.
- the preferred low-frequency range is approximately 20 kHz - 100 kHz.
- the more preferred low-frequency range is approximately 25 kHz - 50 kHz.
- the recommend low-frequency is approximately 30 kHz.
- the preferred high-frequency ultrasound range is approximately 0.7 MHz - 3 MHz.
- the more preferred high-frequency range is approximately 0.7 MHz - 3 MHz.
- the recommend high-frequency is approximately 0.7 MHz.
- the ultrasound waves employed may also vary with respect to amplitude; approximately 1 micron and above.
- the preferred low-frequency amplitude is approximately 30 microns - 100 microns.
- the recommended low-frequency amplitude is approximately 100 microns.
- the high-frequency amplitude can be 1 micron and above.
- the preferred high-frequency amplitude is approximately 5 microns.
- the recommended high-frequency amplitude is approximately 10 microns.
- Figure 2 depicts a cross-sectional view of an alternative configuration of the present invention comprising a feed channel 6 running through the transducer 2 and horn 3 before ending in a feed orifice 7 located within the inner cavity 5 of the cavitation chamber 4.
- tubing 8 Connected to the proximal end of the feed channel 6, tubing 8 carries coupling medium, not shown, to the feed channel 6. The coupling medium then flows through the feed channel 6 and into the inner cavity 5 of the cavitation chamber 4.
- Tubing 8 may be attached to a pump, not shown, as to force coupling medium through the feed channel 6 and into the inner cavity 5 of the cavitation chamber 4.
- the pumping unit creates a general positive pressure against the surface of the treated wound.
- Figure 3 depicts a cross-sectional view of an alternative configuration of the present invention comprising a feed channel 6 running through the horn 3 before ending in a feed orifice 7 located within the inner cavity 5 of the cavitation chamber 4 and an extraction channel 9 beginning at an extraction orifice 10 located within the inner cavity 5 of the cavitation chamber 4 and running through the horn 3.
- tubing 8 carries coupling medium to the feed channel 6.
- the coupling medium may be gravity fed into the feed channel 6 by means of an IV bag, or similar reservoir, located above the device. The coupling medium then flows through the feed channel 6 and into the inner cavity 5 of the cavitation chamber 4, providing delivery of fresh coupling medium and/or drugs to the wound bed.
- the emitted ultrasound waves drive the coupling medium up the extraction channel 9.
- Tubing 11 attached to the extraction channel 9 carries the extracted coupling medium away from the present invention.
- the tubing 8 may be attached to a pump as to force coupling medium through the feed channel 6 and into the inner cavity 5 of the cavitation chamber 4.
- the extraction orifice 10 and/or extraction channel 9 may have a smaller internal diameter at one or more points than the smallest internal diameter within the feed channel 6 and feed orifice 7.
- the resulting differential in flow of the coupling medium in and out of the inner cavity 5 of the cavitation chamber 4 maintains a general positive pressure against the surface of the wound being treated, while permitting the coupling medium to flow out of the inner cavity 5 of the cavitation chamber 4 by means of the extraction channel 9.
- the coupling medium carries away from the wound removed necrotic tissue, infectious agents, and/or other contaminants.
- the tubing 11, as depicted in Figure 3, may be attached to a vacuum as to pull coupling medium out of the inner cavity 5 of the cavitation chamber 4 and up the extraction channel 9.
- the vacuum unit draws coupling medium from the feed channel 6 into the inner cavity 5 of the cavitation chamber 4.
- the feed channel 6 and/or feed orifice 7 may have a smaller internal diameter at one or more points than the smallest internal diameter of the extraction channel 9 and extraction orifice 10.
- the resulting differential in flow of the coupling medium in and out of the inner cavity 5 of the cavitation chamber 4 maintains a general negative pressure against the wound being treated, while permitting fresh coupling medium to flow into the inner cavity 5 of the cavitation chamber 4 through the feed orifice 7.
- the present invention may contain a vacuum attached to tubing 11 and a pump attached to the tubing 8.
- the vacuum unit and the pump may be used in conceit to create a flow differential of the coupling medium into and out of the inner cavity 5 of the cavitation chamber 4.
- the concerted use of a vacuum and pump allows the user to regulate and adjust the pressure applied to the surface of the wound being treated.
- the concerted use of a vacuum and pump also enables the user to alternate between applying general negative and positive pressure against the surface of the wound.
- Figure 4 depicts a cross-sectional view of an alternative configuration of the present invention comprising a ultrasound transducer 2, a horn 3 located at the distal end of the transducer 2, an ultrasound tip 12 at the distal end of the horn 3, and a cavitation chamber 4 located at or near the distal end of horn 3.
- the cavitation chamber 4 comprises an inner cavity 5 open at its base, capable of holding a fluid, non-atomized, coupling medium not shown.
- the cavitation chamber 4 may, but need not, envelope tip 12.
- the tip may be located within or outside of the cavitation chamber.
- the cavitation chamber 4 may be integral with the horn 3 and/or tip 12.
- the cavitation chamber 4 may be a separate piece attached to the horn 3 and/or tip 12 by mechanical means 13.
- Other means of attaching the cavitation chamber such as, but not limited to, chemical or magnetic, may be equally effective.
- the means of attaching the cavitation chamber 4 to horn 3 or tip 12 may be such as to allow the cavitation chamber 4 to be removed and replaced by the user.
- a removable cavitation chamber enables the user to adjust the size and/or configuration of the treatment area as to conform to the wound being treated.
- the tip 12 may be integral with the horn 3, outer apex of the cavitation chamber 4, and/or inner apex of cavitation chamber 12. Alternatively, the tip 12 may be a separate piece attached to the horn 3, outer apex of the cavitation chamber 4, the inner apex of the cavitation chamber 4, or any combination thereof.
- the means of attaching the tip 12 to the horn 3, to the outer apex of the cavitation chamber 4, or to the inner apex of the cavitation chamber 4 may be such as to allow the tip 12 to be removed and replaced by the user.
- a removable tip enables the user to adjust delivery of ultrasound waves as to conform to the wound being treated and coupling medium being used.
- the inner apex of the cavitation chamber refers to the region at or near the top of inner cavity 5. An ultrasound tip is located at the apex of the inner cavity if it transmits longitudinal ultrasound waves into the wound.
- the configuration may further comprise a feed channel 6 running through the transducer 2 and horn 3 before ending in a feed orifice 7 located within the tip 12.
- tubing 8 Connected to the proximal end of the feed channel 6, tubing 8 carries coupling medium to the feed channel 6. The coupling medium then flows through the feed channel 6 and into the inner cavity 5 of the cavitation chamber 4.
- the tubing 8 may be attached to a pump as to force coupling medium through the feed channel 6 and into the inner cavity of 5 the cavitation chamber 4.
- Figure 5 depicts a cross-sectional view of an alternative configuration of the present invention comprising a feed channel 6 running through a portion of the device before ending in a feed orifice 7 located within the tip 12 and an extraction channel 9 beginning at an extraction orifice 10 located within the tip 12 and running through a portion of the device.
- tubing 8 Connected to the proximal end of the feed channel 6, tubing 8 carries coupling medium to the feed channel 6.
- the coupling medium then flows through the feed channel 6 and into the inner cavity 5 of the cavitation chamber 4.
- Tubing 11 attached to the extraction channel 9 carries the extracted coupling medium away from the device.
- the cavitation chamber 4 depicted in detail in Figures 6a-6b, comprises an inner cavity
- the cavitation chamber 4 may be constructed entirely from an autoclavable metallic and/or plastic substance as to permit sterilization after use.
- the cavitation chamber 4 may also be constructed entirely from a supple material, such as, but not limited to, a polymer or plastic.
- the cavitation chamber 4 may comprise a metallic apex 14 and a supple base 15.
- the supple base 15 may be constructed from a variety of materials such as, but not limited, to plastics or polymers.
- the material used to construct the supple base 15 may be thin film or sheet. Alternatively, the material used to construct the supple base 15 may be of sufficient rigidity to permit the chamber to retain geometric shape.
- Constructing the cavitation chamber 4 in whole or in part of a supple material allows the cavitation chamber 4 to conform to the contours of the patient's body when the wound treatment device of the present invention is pressed against the patient. Conforming to the patient's body, the cavitation chamber 4 is capable of forming a better seal as to retain coupling medium during treatment. Adding a liquid sealant 16 to the base of the cavitation chamber 4 further enhances the seal between base of the cavitation chamber and the patient's skin.
- the liquid sealant 16 may comprise, but is not limited to, silicon gel, medical gel, medical adhesive, or water.
- the cavitation chamber 4 in whole or in part of a supple material allows the user to create an alternating general positive and general negative pressure against the wound by pushing down and lifting up on the device; similar in motion and effect to a plumber using a plunger to repair a clogged toilet.
- the base of cavitation chamber 4 may have an accordion like configuration, an example of which is depicted in Figure 7.
- feed port 17 and extraction port 18 within the sides of the cavitation chamber 4 permit coupling medium to be fed into and extracted from the inner cavity 5.
- Tubing 19 attached to feed port 17 carries the coupling medium to the cavitation chamber 4.
- Tubing 20 attached to the extraction port 18 carries the extracted coupling medium away from the cavitation chamber 4.
- the tubing 19 may be attached to a pump as to force coupling medium through the feed port 17 and into the inner cavity 5. Forcing the coupling medium into the inner cavity 5, the pump creates a general positive pressure against the surface of the wound.
- the extraction port 18 may have a smaller internal diameter at one or more points than the smallest internal diameter of feed port 17.
- the resulting differential in flow of the coupling medium in and out of the inner cavity 5 maintains a general positive pressure against the surface of the wound being treated while permitting coupling medium to flow out of the extraction port 18.
- the coupling medium carries away from the wound removed necrotic tissue, infectious agents, and/or other contaminants.
- the tubing 20 may be attached to a vacuum as to pull coupling medium out of the inner cavity 5. Extracting the coupling medium from the inner cavity 5, the vacuum creates a general negative pressure against the surface of the treated wound.
- the feed port 17 may have a smaller internal diameter at one or more points than the smallest internal diameter of the extraction port 18. The resulting differential in flow of the coupling medium in and out of the inner cavity 5 maintains a general negative pressure against the surface of the wound being treated while permitting fresh coupling medium to flow into the inner cavity 5 through the feed port 17.
- the cavitation chamber as depicted in Figures
- the 6a-6b may contain a vacuum unit attached to tubing 20 and a pump attached to tubing 19.
- the vacuum unit and the pump may be used in concert to create a flow differential of the coupling medium into and out the inner cavity 5.
- the concerted use of the vacuum and the pump allows the user to regulate and adjust the general pressure applied to the surface of the wound being treated.
- the concerted use of the vacuum and pump also enables the user to alternate between applying general negative and positive pressure against the surface of the wound.
- mechanical means of connecting the cavitation chamber 4 to the horn 3 and/or tip 12, such that the cavitation chamber 4 may be removed from horn 3 and/or tip 12, may comprise a receptacle 21, on the outer apex of the cavitation chamber 4, that receives a protrusion 22 located at the distal end of the horn 3.
- the cavitation chamber 4 may have a receptacle 23 that receives a protrusion 24 located at the proximal end of the tip 12.
- the protrusions 22 and 24 and receptacles 21 and 23 may be threaded.
- the outer apex of the cavitation chamber is the region opposite the apex of the inner cavity.
- FIGS 8a-8b depicts alternative mechanical means of attaching the cavitation chamber 4 to the hom 3 and/or tip 12.
- the cavitation chamber 4 at its outer apex, may have a protrusion 25 that fits a receptacle 26 located at the distal end of the hom 3.
- the cavitation chamber 4 At its inner apex, may have a metallic protrusion 27 that fits a receptacle 28 located at the proximal end of the tip 12.
- the protrusions 25 and 27 and receptacles 26 and 28 may be threaded.
- the cavitation chamber may comprise any combination of inner-outer-apex- protrusions-receptacles.
- the general three-dimensional geometry of the cavitation chamber may be parabolic, as depicted in Figures 6a-6b and 8a-8b, pyramidal, rectangular, elliptical, or polygonal.
- the geometry of the cavitation chamber's base may be circular, as depicted in
- FIGS. 6a-6b and 8a-8b elliptical, rectangular, triangular, or polygonal.
- the enumerated geometries are merely exemplary and are not meant to be an exclusive or exhaustive listing of possible configurations.
- Figure 9 depicts an ultrasound tip for use with the present invention comprising a radiation 29 surface at its distal end and means of attachment 24 at its proximal end.
- the means of attachment 24 may be, but are not limited to, mechanical, chemical, or magnetic, and the means of attachment 24 serve to secure the device to the inner apex of a cavitation chamber and/or the distal end of an ultrasound horn during treatment.
- the radiation surface 29, during treatment emits ultrasound waves that induce cavitations within a coupling medium held with a cavitation chamber.
- FIGS 10a-10d depicts cross-sectional views of various ultrasound tip configurations that may be used with the present invention.
- the ultrasound tip comprises, at its distal end, a radiation surface 29 from which ultrasound waves are emitted.
- the radiation surface 29 may comprise a convex or concave geometry, as depicted in Figure 10a and 10b respectively.
- the radiation surface 28 may comprise a planar geometry.
- the radiation surface 29, as depicted in Figure 10d may comprise an inner convex geometry surrounded by an outer concave geometry.
- Other geometries of the radiation surface 29 may also be effective and the exemplar geometries mentioned are not intended to be an exclusive or exhaustive list.
- the outer peripheral boundary of the ultrasound tips radiation surface may take on a variety of geometries, such as, but not limited to, circular, elliptical, rectangular, triangular, or polygonal.
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- Heart & Thoracic Surgery (AREA)
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Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009518440A JP2009541015A (en) | 2006-06-26 | 2007-06-14 | Ultrasonic wound treatment apparatus and method |
AU2007265288A AU2007265288A1 (en) | 2006-06-26 | 2007-06-14 | Ultrasound wound care device and method |
EP07798535A EP2032112A4 (en) | 2006-06-26 | 2007-06-14 | Ultrasound wound care device and method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/474,695 US20070299369A1 (en) | 2006-06-26 | 2006-06-26 | Ultrasound wound care device and method |
US11/474,695 | 2006-06-26 |
Publications (2)
Publication Number | Publication Date |
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WO2008002773A2 true WO2008002773A2 (en) | 2008-01-03 |
WO2008002773A3 WO2008002773A3 (en) | 2008-11-20 |
Family
ID=38846395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/071166 WO2008002773A2 (en) | 2006-06-26 | 2007-06-14 | Ultrasound wound care device and method |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070299369A1 (en) |
EP (1) | EP2032112A4 (en) |
JP (1) | JP2009541015A (en) |
KR (1) | KR20090039734A (en) |
CN (1) | CN101505706A (en) |
AU (1) | AU2007265288A1 (en) |
WO (1) | WO2008002773A2 (en) |
Cited By (4)
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EP2147698A1 (en) * | 2008-07-23 | 2010-01-27 | Enraf Nonius B.V. | An ultrasound treatment head for an apparatus for treating a patient with ultrasound |
WO2012085920A1 (en) | 2010-12-22 | 2012-06-28 | Ilan Feferberg | Skin ulcer treatment |
JP2013502246A (en) * | 2009-08-18 | 2013-01-24 | アイ、テック、ケア | Parameters for an ultrasonic device with means for generating a high-density ultrasonic beam |
WO2014053232A1 (en) * | 2012-10-01 | 2014-04-10 | Mölnlycke Health Care Ab | Wound therapy device |
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US8235919B2 (en) | 2001-01-12 | 2012-08-07 | Celleration, Inc. | Ultrasonic method and device for wound treatment |
US20040030254A1 (en) * | 2002-08-07 | 2004-02-12 | Eilaz Babaev | Device and method for ultrasound wound debridement |
JP2010501287A (en) * | 2006-08-25 | 2010-01-21 | ババエヴ,エイラズ | Portable ultrasound device for wound treatment |
US8491521B2 (en) | 2007-01-04 | 2013-07-23 | Celleration, Inc. | Removable multi-channel applicator nozzle |
US8048044B2 (en) * | 2007-08-14 | 2011-11-01 | Stryker Corporation | Drug delivery system |
US20090198157A1 (en) * | 2008-02-01 | 2009-08-06 | Eilaz Babaev | Ultrasound moxibustion method and device |
US20110112445A1 (en) * | 2008-04-11 | 2011-05-12 | GP Investmenti S.r.l | Handpiece for Ultrasound Treatments of Human Tissue |
US9414968B2 (en) | 2008-09-05 | 2016-08-16 | Smith & Nephew, Inc. | Three-dimensional porous film contact layer with improved wound healing |
US10238849B2 (en) * | 2009-07-30 | 2019-03-26 | Alma Lasers Ltd. | Sonotrode |
US8708981B2 (en) † | 2011-05-26 | 2014-04-29 | Kci Licensing, Inc. | Systems and methods of stimulation and activation of fluids for use with instillation therapy |
EP3159020B1 (en) | 2011-06-07 | 2019-11-06 | Smith & Nephew plc | Wound contacting members |
US20130304000A1 (en) * | 2012-05-14 | 2013-11-14 | Christian James Pentell | Body piercing cleansing and sanitation device |
US9050053B2 (en) * | 2013-02-15 | 2015-06-09 | Naimco, Inc. | Ultrasound device with cavity for conductive medium |
CN104338190A (en) * | 2013-07-25 | 2015-02-11 | 厚凯(北京)医疗科技有限公司 | Ultrasonic non-contact wound debridement and treatment apparatus capable of enhancing cavitation effect |
WO2015080901A1 (en) | 2013-11-26 | 2015-06-04 | Celleration Inc. | Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing |
WO2015172104A1 (en) * | 2014-05-09 | 2015-11-12 | Kci Licensing, Inc. | Debriding dressing for use with negative pressure and fluid instillation |
CN105030399A (en) * | 2015-06-19 | 2015-11-11 | 李建锋 | Burn rehabilitation therapy apparatus for general surgery department |
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KR101692280B1 (en) * | 2015-07-15 | 2017-01-17 | (주)클래시스 | Apparatus and method for generating vaccum pulse for medical use |
CN110772723A (en) * | 2019-11-08 | 2020-02-11 | 昆明医科大学 | Skin tissue treatment system |
CN110787379A (en) * | 2019-11-08 | 2020-02-14 | 昆明医科大学 | Melanin treatment system |
KR102488054B1 (en) * | 2022-07-22 | 2023-01-13 | 조대희 | Multi axis ultrasonic torsion energy injection system and method thereof |
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- 2007-06-14 WO PCT/US2007/071166 patent/WO2008002773A2/en active Application Filing
- 2007-06-14 EP EP07798535A patent/EP2032112A4/en not_active Withdrawn
- 2007-06-14 AU AU2007265288A patent/AU2007265288A1/en not_active Abandoned
- 2007-06-14 CN CNA2007800316924A patent/CN101505706A/en active Pending
- 2007-06-14 KR KR1020097001667A patent/KR20090039734A/en not_active Application Discontinuation
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2147698A1 (en) * | 2008-07-23 | 2010-01-27 | Enraf Nonius B.V. | An ultrasound treatment head for an apparatus for treating a patient with ultrasound |
US8409100B2 (en) | 2008-07-23 | 2013-04-02 | Enraf-Nonius B.V. | Ultrasound treatment head for an apparatus for treating a patient with ultrasound |
JP2013502246A (en) * | 2009-08-18 | 2013-01-24 | アイ、テック、ケア | Parameters for an ultrasonic device with means for generating a high-density ultrasonic beam |
WO2012085920A1 (en) | 2010-12-22 | 2012-06-28 | Ilan Feferberg | Skin ulcer treatment |
US9345909B2 (en) | 2010-12-22 | 2016-05-24 | Ilan Feferberg | Skin ulcer treatment |
WO2014053232A1 (en) * | 2012-10-01 | 2014-04-10 | Mölnlycke Health Care Ab | Wound therapy device |
US20150258259A1 (en) * | 2012-10-01 | 2015-09-17 | Mölnlycke Health Care Ab | Wound therapy device |
AU2013327251B2 (en) * | 2012-10-01 | 2017-04-13 | Molnlycke Health Care Ab | Wound therapy device |
US9844614B2 (en) | 2012-10-01 | 2017-12-19 | Mölnlycke Health Care Ab | Wound therapy device |
Also Published As
Publication number | Publication date |
---|---|
WO2008002773A3 (en) | 2008-11-20 |
JP2009541015A (en) | 2009-11-26 |
AU2007265288A1 (en) | 2008-01-03 |
EP2032112A2 (en) | 2009-03-11 |
US20070299369A1 (en) | 2007-12-27 |
EP2032112A4 (en) | 2010-04-07 |
CN101505706A (en) | 2009-08-12 |
KR20090039734A (en) | 2009-04-22 |
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