CN110787379A - Melanin treatment system - Google Patents
Melanin treatment system Download PDFInfo
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- CN110787379A CN110787379A CN201911069363.XA CN201911069363A CN110787379A CN 110787379 A CN110787379 A CN 110787379A CN 201911069363 A CN201911069363 A CN 201911069363A CN 110787379 A CN110787379 A CN 110787379A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0034—Skin treatment
Abstract
The invention relates to the field of skin tissue engineering repair, in particular to a melanin treatment system, wherein: the pulse signal transmitting unit is used for receiving basic data and forming pulse data output matched with the basic data according to the basic data; the conversion unit is connected with the pulse signal transmitting unit and used for receiving the pulse data and forming ultrasonic data matched with the pulse data according to the pulse data; and the output unit is connected with the conversion unit and used for receiving the ultrasonic data and projecting the ultrasonic data to a target area matched with the basic data.
Description
Technical Field
The invention relates to the field of skin tissue engineering repair, in particular to a melanin treatment system.
Background
Melanocytes are animal cells with melanin or other similar pigments, usually located in the epidermis and other places of the skin, which synthesize and secrete melanin when the skin is subjected to excessive exposure to ultraviolet rays in the sun, or external stimuli such as pressure, friction, etc., and scarring after trauma and burns. Since the metabolism in the body is often disturbed due to the influence of modern living stress, the melanin in the skin cannot be completely removed even after the 28-day metabolism period. As melanin accumulates in different skin layers, the dermoscopy will appear as a differently colored stain. Black indicates melanin is located in the stratum corneum and upper epidermis, brown indicates melanin is located in the epidermis, gray to gray blue indicates melanin is located in the dermal papilla, and blue indicates melanin is located in the dermal reticular. At present, two methods for removing skin melanin are mainly used, one method is laser treatment, deposited melanin is mostly removed from the epidermal layer of the skin, the generation of the melanin cannot be inhibited from the root, and the skin feels burning or scars are left. For example, two methods are mainly used for removing melanin, one is laser treatment, laser with different wavelengths can be absorbed by special colors and pigments in skin by utilizing visible light with high-intensity instant capability of laser, fuel particles are broken and vaporized by laser energy to seal blood vessels, and then the body absorbs the fuel particles to remove the melanin from the body, so that scars are left due to improper melanin removal operation, depressed scars or hyperplastic scars are easily formed, and pigmentation is caused again; even the retina of the eye is injured due to improper operation, blindness is seriously caused, certain danger exists, and melanin pigmentation cannot be eradicated. The other is a medicine for removing skin melanin: the medicine contains strong corrosive agent of acidic substance, causes burning sensation, and damages the dermis layer of skin when being used excessively, thereby leaving permanent scar or pigmentation.
Disclosure of Invention
In view of the above technical problems of repair, the present invention provides a melanin treatment system. Specifically, a melanin treatment system, wherein: comprises the steps of (a) preparing a mixture of a plurality of raw materials,
the pulse signal transmitting unit is used for receiving basic data and position information and forming pulse data output matched with the basic data according to the basic data;
the conversion unit is connected with the pulse signal transmitting unit and used for receiving the pulse data and forming ultrasonic data matched with the pulse data according to the pulse data, wherein the ultrasonic data at least comprises ultrasonic irradiation information, sound wave transmission information and sound wave deflection angle information; the sound intensity of the ultrasonic data is not less than 0.2W/cm2；
And the output unit is connected with the conversion unit and used for receiving the ultrasonic data and projecting the ultrasonic data to a target area matched with the position information.
Preferably, the melanin treatment system further comprises:
the acquisition positioning device is used for acquiring reference data of a target area and forming acquisition data and the position information according to the reference data;
and the computing device is connected between the positioning device and the pulse signal transmitting unit and used for computing and forming the basic data according to the acquired data, forming pulse data according to the basic data and outputting the pulse data to the pulse signal generating unit by combining the position information.
Preferably, in the melanin treatment system, the acquired data includes a first characteristic reference value, a second characteristic reference data, and a third characteristic reference data, and the basic data includes a first characteristic basic value, a second characteristic basic value, and a third characteristic basic value;
the acquisition positioning device forms the first characteristic basic value according to the first characteristic reference value in the state of acquiring the first characteristic reference value; alternatively, the first and second electrodes may be,
forming a second characteristic basic value according to the second characteristic reference value in the state of acquiring the second characteristic reference value; alternatively, the first and second electrodes may be,
and forming the third feature basic value according to the third feature reference value in the state of acquiring the third feature reference value.
Preferably, in the melanin treatment system, the pulse signal transmitting unit includes at least:
the pulse signal generator is used for receiving the first characteristic basic value and forming first pulse signal data output according to the first characteristic basic value; alternatively, the first and second electrodes may be,
the second pulse signal data output is formed according to the second characteristic basic value; alternatively, the first and second electrodes may be,
and the third pulse signal data output is formed according to the third characteristic basic value.
Preferably, the melanin treatment system further comprises a fixing device for accommodating the conversion unit.
Preferably, in the melanin treatment system, the fixing device further includes a filling area inside, the filling area is disposed adjacent to the converting unit, and an opening of the filling area faces away from the converting unit.
Preferably, in the melanin treatment system, the filling area is used for accommodating the filling medium.
Preferably, in the melanin treatment system, the filling medium at least includes deionized water, a coupling agent, and PVA.
Compared with the prior art, the invention has the advantages that: the pulse signal transmitting unit is used for receiving ultrasonic irradiation information, sound wave transmission information, sound wave deflection angle information, ultrasonic energy information and position information, forming electric signal form pulse data matched with the basic data according to the basic data and outputting the electric signal form pulse data to the conversion unit, and the conversion unit converts the pulse data into electric signal form pulse data with the sound intensity not less than 0.2W/cm2And the ultrasonic waves are transmitted to an output unit which transmits the ultrasonic wavesThe skin is irradiated by radiation, so that ultrasonic waves act on a melanin area to activate Agouti signal protein and a receptor thereof, G protein coupling and a receptor thereof in skin tissues, and fibroblasts secrete DKKI cytokines to block a Wnt/13-catenin pathway, so that the generation of tyrosinase, the activity of tyrosinase or an intermediate for interfering the generation of melanin is inhibited, the continuous generation and deposition of melanin are inhibited, meanwhile, inflammatory cytokines such as interleukin 1(1L-1), interleukin 6(1L-6), tumor necrosis factor β (TNF- β) and the like secreted by inflammatory cells are inhibited to form melanin, the aims of inhibiting the generation and deposition of different cortical melanin from root without pain and trace are achieved, the safety is high, the requirement on operators is low, and the implementation is easy.
Drawings
Fig. 1 is a schematic structural diagram of a melanin treatment system according to an embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
Example one
As shown in fig. 1, a melanin treatment system, primarily for treating skin, wherein: comprises the steps of (a) preparing a mixture of a plurality of raw materials,
the pulse signal transmitting unit is used for receiving basic data and position information and forming pulse data output matched with the basic data according to the basic data; the basic data comprises target size and color, the pulse data is presented in the form of electric signals, and the position information is the area where the melanin is located.
The conversion unit is connected with the pulse signal transmitting unit and used for receiving the pulse data and forming ultrasonic data matched with the pulse data according to the pulse data, and the ultrasonic data at least comprises ultrasonic irradiation information, sound wave transmission information and sound wave deflection angle informationInformation of ultrasonic energy, and the sound intensity of the ultrasonic data is not less than 0.2W/cm2(ii) a The ultrasonic data is presented in the form of ultrasonic wave, and the sound intensity of the ultrasonic data is not less than 0.2W/cm2I.e. the sound intensity is not less than 0.2W/cm2The ultrasonic waves of (4).
And the output unit is connected with the conversion unit and used for receiving the ultrasonic data and projecting the ultrasonic data to a target area matched with the position information. The ultrasound data acted on the area where melanin was located, activating the Agouti signal protein and its receptor, G protein coupling and receptor in skin tissue, causing fibroblasts to secrete DKKI cytokines to block the Wnt/13-catenin pathway. Thereby inhibiting the production of tyrosinase, the activity of tyrosinase or interfering with the production of melanin intermediates, thereby inhibiting the continuous production and deposition of melanin.
The specific working principle of the melanin treatment system is as follows: the pulse signal transmitting unit is used for receiving ultrasonic irradiation information, sound wave transmission information, sound wave deflection angle information, ultrasonic energy information and position information, forming electric signal form pulse data matched with the basic data according to the basic data and outputting the electric signal form pulse data to the conversion unit, and the conversion unit converts the pulse data into electric signal form pulse data with the sound intensity not less than 0.2W/cm2The ultrasonic waves are transmitted to an output unit, the ultrasonic waves are irradiated to the skin by the output unit, so that the ultrasonic waves act on the area where the melanin is located, Agouti signal protein and a receptor thereof as well as G protein coupling and a receptor thereof in skin tissues are activated, and then the fibroblast secretes DKKI cell factors to block a Wnt/13-catenin channel, so that the generation of tyrosinase, the activity of tyrosinase or an intermediate for interfering the generation of the melanin is inhibited, the continuous generation and deposition of the melanin are inhibited, meanwhile, inflammatory cell factors such as interleukin 1(1L-1), interleukin 6(1L-6), tumor necrosis factor β (TNF- β) and the like secreted by inflammatory cells are inhibited to form the melanin, and the aims of inhibiting the generation and deposition of different cortical melanin from the root without pain and trace are achieved.
As a further preferred embodiment, the melanin treatment system described above, further comprising:
the acquisition positioning device is used for acquiring reference data of a target area and forming acquisition data and the position information according to the reference data; further, the collected data comprises a first characteristic reference value, a second characteristic reference data and a third characteristic reference data, and the basic data comprises a first characteristic basic value, a second characteristic basic value and a third characteristic basic value;
and the computing device is connected between the positioning device and the pulse signal transmitting unit and used for computing and forming the basic data according to the acquired data, forming pulse data according to the basic data and outputting the pulse data to the pulse signal generating unit by combining the position information.
The acquisition positioning device forms the first characteristic basic value according to the first characteristic reference value in the state of acquiring the first characteristic reference value; alternatively, the first and second electrodes may be,
forming a second characteristic basic value according to the second characteristic reference value in the state of acquiring the second characteristic reference value; alternatively, the first and second electrodes may be,
and forming the third feature basic value according to the third feature reference value in the state of acquiring the third feature reference value.
For example, when the melanin plaques are in the epidermis layer of the skin tissue and are lighter in color, this state may be defined as the first characteristic reference value, when the melanin plaques are in the subcutaneous layer and are darker in color, this state may be defined as the second characteristic reference value, otherwise, the melanin plaques are located at the third characteristic reference value.
The first characteristic basic value formed according to the first characteristic reference value is an electric signal with high frequency and low intensity; the second characteristic basic value formed according to the second characteristic reference value is a low-frequency and high-intensity electric signal.
The third characteristic basic value formed according to the third characteristic reference value is an electric signal between a high frequency and a low intensity and between a low frequency and a high intensity. When the third characteristic reference value is close to the first characteristic reference value, the third characteristic basic value is close to the first characteristic basic value, otherwise, the third characteristic basic value is close to the second characteristic basic value.
As a further preferred embodiment, the melanin treatment system described above, wherein the pulse signal transmitting unit includes at least:
the pulse signal generator is used for receiving the first characteristic basic value and forming first pulse signal data output according to the first characteristic basic value; alternatively, the first and second electrodes may be,
the second pulse signal data output is formed according to the second characteristic basic value; alternatively, the first and second electrodes may be,
and the third pulse signal data output is formed according to the third characteristic basic value.
As a further preferred embodiment, the melanin treatment system further comprises a fixing device for accommodating the conversion unit, and further, the conversion unit is fixed in the fixing device through a sterile membrane. The fixing device is characterized in that the fixing device also comprises a filling area, the filling area is adjacent to the conversion unit, and an opening of the filling area faces away from the conversion unit. The filling area is used for containing the filling medium. The filling medium at least comprises deionized water, coupling agent and PVA. The ultrasound is brought to the treatment area by filling the medium.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Although various aspects of the invention are presented in the independent claims, other aspects of the invention comprise combinations of features from the described embodiments and/or the dependent claims with the features of the independent claims, and not solely the combinations explicitly presented in the claims.
It is noted herein that while the above describes example embodiments of the invention, these descriptions should not be viewed in a limiting sense. Rather, several variations and modifications are possible without departing from the scope of the invention as defined in the appended claims.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Claims (8)
1. A melanin treatment system, comprising: comprises the steps of (a) preparing a mixture of a plurality of raw materials,
the pulse signal transmitting unit is used for receiving basic data and position information and forming pulse data output matched with the basic data according to the basic data;
the conversion unit is connected with the pulse signal transmitting unit and used for receiving the pulse data and forming ultrasonic data matched with the pulse data according to the pulse data, wherein the ultrasonic data at least comprises ultrasonic irradiation information, sound wave transmission information and sound wave deflection angle information; the sound intensity of the ultrasonic data is not less than 0.2W/cm2；
And the output unit is connected with the conversion unit and used for receiving the ultrasonic data and projecting the ultrasonic data to a target area matched with the position information.
2. A melanin treatment system according to claim 1, further comprising:
the acquisition positioning device is used for acquiring reference data of a target area and forming acquisition data and the position information according to the reference data;
and the computing device is connected between the positioning device and the pulse signal transmitting unit and used for computing and forming the basic data according to the acquired data, forming pulse data according to the basic data and outputting the pulse data to the pulse signal generating unit by combining the position information.
3. The melanin treatment system according to claim 2, wherein the collected data includes a first characteristic reference value, a second characteristic reference data, and a third characteristic reference data, and the basic data includes a first characteristic basic value, a second characteristic basic value, and a third characteristic basic value;
the acquisition positioning device forms the first characteristic basic value according to the first characteristic reference value in the state of acquiring the first characteristic reference value; alternatively, the first and second electrodes may be,
forming a second characteristic basic value according to the second characteristic reference value in the state of acquiring the second characteristic reference value; alternatively, the first and second electrodes may be,
and forming the third feature basic value according to the third feature reference value in the state of acquiring the third feature reference value.
4. A melanin treatment system according to claim 3, wherein: the pulse signal transmitting unit includes at least:
the pulse signal generator is used for receiving the first characteristic basic value and forming first pulse signal data output according to the first characteristic basic value; alternatively, the first and second electrodes may be,
the second pulse signal data output is formed according to the second characteristic basic value; alternatively, the first and second electrodes may be,
and the third characteristic basic value is used for receiving the third characteristic basic value, and third pulse signal data is formed according to the third characteristic basic value to output pulse data.
5. A melanin treatment system according to claim 1, wherein: the device also comprises a fixing device used for accommodating the conversion unit.
6. A melanin treatment system according to claim 5, wherein: the fixing device is characterized in that the fixing device also comprises a filling area, the filling area is adjacent to the conversion unit, and an opening of the filling area faces away from the conversion unit.
7. A melanin treatment system according to claim 6, wherein: the filling area is used for containing the filling medium.
8. A melanin treatment system according to claim 7, wherein: the filling medium at least comprises deionized water, coupling agent and PVA.
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