CN110404176A - tumor thermotherapy apparatus and control method thereof - Google Patents
tumor thermotherapy apparatus and control method thereof Download PDFInfo
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- CN110404176A CN110404176A CN201810403014.6A CN201810403014A CN110404176A CN 110404176 A CN110404176 A CN 110404176A CN 201810403014 A CN201810403014 A CN 201810403014A CN 110404176 A CN110404176 A CN 110404176A
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- 230000003993 interaction Effects 0.000 claims abstract description 95
- 238000011282 treatment Methods 0.000 claims description 43
- 238000001514 detection method Methods 0.000 claims description 15
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 13
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0625—Warming the body, e.g. hyperthermia treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
- A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared
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Abstract
The present invention provides a tumor thermotherapy apparatus and a control method thereof, wherein the tumor thermotherapy apparatus includes: the human-computer interaction device is characterized by comprising at least one far infrared radiation unit, wherein the at least one far infrared radiation unit is respectively connected with the power supply module; the power module is connected with the human-computer interaction device. The tumor thermotherapy equipment adopts at least one far infrared radiation unit as a heat source, provides stable far infrared rays with the wavelength close to that of far infrared rays radiated by a human body, performs targeted radiation on a focus part, generates high-efficiency resonance absorption, and realizes better thermotherapy effect.
Description
Technical field
The present invention relates to medical instruments field more particularly to a kind of tumor thermotherapy equipment and its control method.
Background technique
Oncotherapy at present specifically includes that operation, radiotherapy, chemotherapy, biological therapy and the big means of thermotherapy five.Wherein, tumour
Thermotherapy is the method for the 5th kind for the treatment of tumour after operation, radiotherapy, chemotherapy and biological therapy.Tumor thermotherapy is to utilize related object
Fuel factor of the energy in tissue is managed, tumor tissues temperature is made to rise to effective treatment temperature, and maintains a period of time, with
Kill tumour cell but the not tumor therapeuticing method of injuring normal cell.The basic principle is that: human normal tissue is in body temperature liter
In the case where height, blood vessel dilatation, blood flow accelerates, and heat dissipation is very fast.Due to this adjustment effect of body, it ensure that and increased in body temperature
When, or even when body temperature reaches 41.5~43 DEG C, tissue damage is little, and can repair.And tumor vessel is abundant, capillary
Net stores a large amount of blood, organizes interior vascular morphology exception, mixed and disorderly distortion, forms thrombus or embolism vulnerable to compressive strain.In addition tumour
Interior blood vessel is mostly made of cell monolayer, fragile fragile.Since these new vessels are undergrown lopsided blood vessels, heated
After lose self-control effect, vein can not accelerate to flow back, and tumor by local hypostasis, blood flow is only normal tissue
1%~15%, cause tumor tissues heat dissipation difficult, temperature increases.The temperature of malignant tumor tissue is often higher than normal group neighbouring
Knit 8~10 DEG C of temperature.Same to carry out local heating, tumor vessel neural sensor is unsound, poor to high temperature sensitivity.Tumour hair
The nonelastic outer membrane of thin vascular wall, brittleness is big, is easily broken under high temperature action, and tissue temperature is increased to 40 DEG C if normal, then tumor
Intracorporal temperature can then be increased to 48 DEG C or so, and a large amount of experiment and clinical test prove, tumour cell at 39 DEG C~40 DEG C,
Its activity is suppressed, and increases the trend of apoptosis；At 40 DEG C~42 DEG C, tumour cell can be badly damaged, and can be shorter
Time in it is dead.So this temperature can make tumour cell by Thermal killed completely, and normal tissue is without damage.
Currently, being applied to the heat source of tumor thermotherapy mainly has: microwave, radio frequency, ultrasound and four kinds of near-infrared.Wherein microwave and
Radio frequency can have ionising radiation and radiocontamination as the relatively conventional of heat source, but using microwave and radio frequency heating, to human body and
Environment generates adverse effect.And ultrasound is used as heat source, since ultrasound is not easy across body cavity and is easy by skeleton
The characteristics of absorption, is often accompanied by more serious side effect in therapeutic process.Conventional infrared heat source, because it cannot be generated with human body
RESONANCE ABSORPTION, the effective depth for penetrating human skin is shallower, and therapeutic effect is limited.Therefore, the tumor thermotherapy of the prior art is controlled
Therapeutic effect is poor.
Summary of the invention
For the one or more of problem in the prior art, in one aspect of the invention, a kind of tumor thermotherapy is provided
Equipment.
In another aspect of this invention, the control method of above-mentioned tumor thermotherapy is provided.
In one aspect of the invention, a kind of tumor thermotherapy equipment is provided, comprising: irradiation devices, power module and man-machine
Interactive device, wherein the irradiation devices include at least one far infrared radiation unit, at least one described far infrared radiation list
Member is connect with the power module respectively；
Wherein, the power module is connect with the human-computer interaction device.
According to an aspect of the present invention, the tumor thermotherapy equipment further include:
Software is analyzed with the first infrared thermal imagery sensor of human-computer interaction device connection and its corresponding infrared data
System；
And/or further include mechanical arm, the irradiation devices are set to the mobile terminal of the mechanical arm.
Preferably, the irradiation devices are detachably connected with the mechanical arm.
Preferably, the first infrared thermal imagery sensor is set to the mobile terminal of the mechanical arm, for acquiring
The temperature distribution information and is sent to described by target object by the local surface temperature distributed intelligence of the far infrared radiation
Human-computer interaction device；Preferably, the acquisition is acquisition in real time or interval acquisition.
As further preferred scheme, the infrared data analyzing software system is based on the surface temperature distribution information,
It derives the three dimensional temperature distributed intelligence of corresponding region, and the three dimensional temperature distributed intelligence is sent to the human-computer interaction and is filled
It sets.
The human-computer interaction device, can be using intelligence computations devices such as computers, including processor and man-machine friendship
Mutual interface.Processor be used for obtains and on human-computer interaction interface displaying target object bulk temperature distributed intelligence (integrally it is red
Outer thermal map), target object is by regional area position/shape size/Temperature Distribution (local infrared chart) of far infrared radiation etc.
The distance between information, irradiation devices and target object information and the working condition of at least one far infrared radiation unit letter
Breath；And spatial position and shape size information according to the pre-selected targeted treatment area of operator, Xiang Suoshu mechanical arm
And/or the irradiation bed sends positioning signal, to adjust the relative space position of the irradiation devices and targeted treatment area；With
And the local temperature distributed intelligence according to the pre-selected temperature controlling mode of operator, targeted treatment area, Xiang Suoshu power module
Control signal is sent, to adjust the electrical power that the power module is exported at least one described far infrared radiation unit.
According to an aspect of the present invention, the tumor thermotherapy equipment further includes fixed or movable irradiation bed, preferably
Ground, the irradiation bed are connect with the human-computer interaction device, and vertically and/or preceding under the control of the human-computer interaction device
Afterwards and/or left and right directions is mobile.
According to an aspect of the present invention, the irradiation bed further include: at least one far infrared radiation unit, it is described at least
One far infrared radiation unit is connect with the power module respectively, it is preferable that the irradiation bed further include: mattress, it is described extremely
A few far infrared radiation unit is set to the inside of the mattress.
According to an aspect of the present invention, the far infrared radiation unit includes radiation diaphragm, is set on the radiation diaphragm
There are electrode and temperature sensor, the electrode is connect by contact conductor with the power module, the temperature sensor acquisition
The temperature information of the radiation diaphragm, and the temperature information is sent to the human-computer interaction device.
According to an aspect of the present invention, the far infrared radiation energy of the radiation diaphragm concentrates on 4~14um wave band, spoke
Penetrating peak wavelength is 8~10um.
Preferably, the radiation diaphragm includes graphene film.
As further preferred scheme, the graphene film is the graphene film of CVD method preparation.
According to an aspect of the present invention, the tumor thermotherapy equipment further include:
Clinical thermometer, the temperature information of the specific region for acquiring target object, and the temperature information is sent to institute
State human-computer interaction device；Wherein, the clinical thermometer is connect by wired or wireless way with the human-computer interaction device.
According to an aspect of the present invention, the irradiation devices further include:
The safe distance detection module being connect with the human-computer interaction device, for detecting the irradiation devices and target pair
As the distance between information, and the range information is sent to the human-computer interaction device；Preferably, the safe distance inspection
Surveying module includes depth transducer and/or time-of-flight sensor and/or diffusing reflection formula photoelectric sensor and its corresponding data
Analyzing software system.
According to an aspect of the present invention, the tumor thermotherapy equipment further include:
Software is analyzed with the second infrared thermal imagery sensor of human-computer interaction device connection and its corresponding infrared data
System for acquiring the overall surface temperature distribution information on target object, and the temperature distribution information is sent to described
Human-computer interaction device, it is preferable that the infrared data analyzing software system is based on the surface temperature distribution information, derives
The three dimensional temperature distributed intelligence of corresponding region, and the three dimensional temperature distributed intelligence is sent to the human-computer interaction device.
According to an aspect of the present invention, the irradiation devices further include:
The VISIBLE LIGHT EMISSION device connecting with the power module, the VISIBLE LIGHT EMISSION device are set to described at least one
A far infrared radiation unit is formed by geometrical characteristic position, for intuitively indicating radiation iris action in the remote of target object
IR radiation region and radiation intensity；Preferably, the power module is while adjusting the radiation diaphragm input electric power,
It will indicate that the electrical power of the electrical power size is loaded into the VISIBLE LIGHT EMISSION device, to control the VISIBLE LIGHT EMISSION dress
The luminous intensity set, the electrical power of the far infrared radiation unit are the electrical power or multiple remote red of a far infrared radiation unit
The average value of the electrical power of external radiation unit.
According to an aspect of the present invention, the tumor thermotherapy equipment further include: photopic vision module, for determining
The relative space position information between irradiation devices and target object and/or between the irradiation bed and target object is stated, and will
The relative space position information is sent to the human-computer interaction device；Preferably, the photopic vision module includes visible
Light video camera and its corresponding analysis of image data software systems.
According to an aspect of the present invention, the human-computer interaction device further include: interactive interface.
According to an aspect of the present invention, the human-computer interaction device further include: temperature control system, the temperature control system branch
It holds: at least one of conflicting model, constant temperature mode and impact constant temperature alternate mode temperature controlling mode.
In another aspect of this invention, a kind of control method of tumor thermotherapy is provided, the control method includes:
Determine spatial position and the shape size information of the targeted treatment area that target object needs far infrared radiation to treat；
According to the spatial position and shape size information, the sky between irradiation devices and the targeted treatment area is adjusted
Between relative position；
Set temperature controlling mode；
Power module starts, and the far infrared radiation cell operation to match on irradiation devices with targeted treatment area simultaneously radiates
Targeted treatment area, and/or, it irradiates the far infrared radiation cell operation to match in bed with targeted treatment area and radiates target
Treatment region；
Real-time or compartment of terrain obtains the temperature distribution information of targeted treatment area；With
According to pre-selected temperature controlling mode and the temperature distribution information of the targeted treatment area, the irradiation is adjusted
The input electric power of at least one far infrared radiation unit in device and/or irradiation bed.
According to an aspect of the present invention, the targeted treatment area that the determining target object needs far infrared radiation to treat
Spatial position and the step of shape size information, comprising:
It obtains the temperature distribution information of target object entirety and is showed on the interface of human-computer interaction device；
According to the temperature distribution information, treatment region is selected on human-computer interaction device interface, determines the target pair
Spatial position and/or shape size information as needing the targeted treatment area of far infrared radiation treatment.
According to an aspect of the present invention, according to the spatial position and shape size information, irradiation devices and institute are adjusted
The step of stating the relative space position between targeted treatment area, comprising:
According to the spatial position of the targeted treatment area and shape size information, sent to mechanical arm and/or irradiation bed
Positioning signal, to adjust the relative space position of irradiation devices Yu the targeted treatment area.
According to an aspect of the present invention, the temperature controlling mode includes: that conflicting model, constant temperature mode and impact constant temperature are handed over
For at least one of mode.
According to an aspect of the present invention, the real-time or compartment of terrain obtains the temperature distribution information of targeted treatment area,
Include:
Target object is obtained by the local surface temperature distributed intelligence of far infrared radiation；
According to the surface temperature distribution information, the three dimensional temperature distributed intelligence of corresponding region is derived.
Detailed description of the invention
Attached drawing is used to provide further understanding of the present invention, and constitutes part of specification, with reality of the invention
It applies example to be used to explain the present invention together, not be construed as limiting the invention.In the accompanying drawings:
Fig. 1 shows the structural schematic diagrams of the tumor thermotherapy equipment of the embodiment of the present invention；
Fig. 2 indicates the modular structure schematic diagram of the tumor thermotherapy equipment of the embodiment of the present invention；
Fig. 3 indicates the modular structure schematic diagram of the targeted therapy principle of the tumor thermotherapy equipment of the embodiment of the present invention；
Fig. 4 indicates the structural schematic diagram of the mattress of the tumor thermotherapy equipment of the embodiment of the present invention；
Fig. 5 indicates the structural schematic diagram of the far infrared radiation unit of the tumor thermotherapy equipment of the embodiment of the present invention；
Fig. 6 indicates the structural schematic diagram of the irradiation devices of the tumor thermotherapy equipment of the embodiment of the present invention；
Fig. 7 indicates the structural schematic diagram of the VISIBLE LIGHT EMISSION device of the tumor thermotherapy equipment of one embodiment of the invention；
Fig. 8 shows the structural schematic diagrams of the VISIBLE LIGHT EMISSION device of the tumor thermotherapy equipment of another embodiment of the present invention；
Fig. 9 indicates the modular structure schematic diagram of the temperature control principle of the tumor thermotherapy equipment of the embodiment of the present invention.
Wherein in figure: 1, irradiation devices, 2, irradiation bed, 3, power module, 4, human-computer interaction device, 5, temperature sensor,
6, clinical thermometer, 7, photopic vision module；
11, mechanical arm；
121, diaphragm, 122, electrode, 123, safe distance detection module, 124, VISIBLE LIGHT EMISSION device are radiated；
21, mattress, 22, bedstead, the 231, first infrared thermal imagery sensor, the 232, second infrared thermal imagery sensor；
41, display, 42, temperature control system, 43, positioning system.
Specific embodiment
Hereinafter, certain exemplary embodiments are simply just described.As one skilled in the art will recognize that
Like that, without departing from the spirit or scope of the present invention, described embodiment can be modified by various different modes.
Therefore, attached drawing and description are considered essentially illustrative rather than restrictive.
In the description of the present invention, it is to be understood that, term " upper ", " under ", " left side ", " right side ", " preceding ", the instruction such as " rear "
Orientation or positional relationship be based on the orientation or positional relationship shown in the drawings, be merely for convenience of description the present invention and simplification retouch
It states, rather than the device or element of indication or suggestion meaning must have a particular orientation, be constructed and operated in a specific orientation,
Therefore it is not considered as limiting the invention.In the description of the present invention, " multiple " are meant that two or more, remove
It is non-separately to have clearly specific restriction.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected: can
To be mechanical connection, it is also possible to be electrically connected or can mutually communicate；It can be directly connected, it can also be by between intermediary
It connects connected, can be the connection inside two elements or the interaction relationship of two elements.For the ordinary skill of this field
For personnel, the specific meanings of the above terms in the present invention can be understood according to specific conditions.
In the present invention unless specifically defined or limited otherwise, fisrt feature second feature its " upper " or it " under "
It may include that the first and second features directly contact, also may include that the first and second features are not direct contacts but pass through it
Between other characterisation contact.Moreover, fisrt feature second feature " on ", " top " and " above " include first spy
Sign is right above second feature and oblique upper, or is merely representative of first feature horizontal height higher than second feature.Fisrt feature exists
Second feature " under ", " lower section " and " following " be directly below and diagonally below the second feature including fisrt feature, or be merely representative of
First feature horizontal height is less than second feature.
Following disclosure provides many different embodiments or example is used to realize different structure of the invention.In order to
Simplify disclosure of the invention, hereinafter the component of specific examples and setting are described.Certainly, they are merely examples, and
And it is not intended to limit the present invention.In addition, the present invention can in different examples repeat reference numerals and/or reference letter,
This repetition is for purposes of simplicity and clarity, itself not indicate between discussed various embodiments and/or setting
Relationship.In addition, the present invention provides various specific techniques and material example, but those of ordinary skill in the art can be with
Recognize the application of other techniques and/or the use of other materials.
Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings, it should be understood that preferred reality described herein
Apply example only for the purpose of illustrating and explaining the present invention and is not intended to limit the present invention.
As depicted in figs. 1 and 2, in the first embodiment of the present invention, a kind of tumor thermotherapy equipment is provided, comprising:
Irradiation devices 1, power module 3 and human-computer interaction device 4.Wherein, the irradiation devices 1 include at least one far infrared radiation list
First (will be discussed in more detail below), at least one described far infrared radiation unit are connect with the power module 3 respectively, that is,
It says, power module 3 can be individually for each of at least one far infrared radiation unit and be powered.Preferably, far infrared radiation
Unit is small size unit.The power module 3 and the human-computer interaction device 4 connect.Wherein, the far infrared radiation unit
The similar far infrared of far infrared wave length with human body itself radiation is given off, targeting radiation is carried out to lesions position, is generated high
The RESONANCE ABSORPTION of efficiency realizes better therapeutic effect.
As shown in Figure 1, the tumor thermotherapy equipment further includes the control mould of mechanical arm 11 and the control movement of mechanical arm 11
Block, the irradiation devices 1 are set to the mobile terminal of the mechanical arm 11, according to a preferred embodiment of the present invention, the spoke
It is detachably connected according to device 1 and the mechanical arm 11, in this way, it is right that the irradiation devices 1 to match with patient's focal size can be selected
Lesions position is oriented, accurately treats.The graphene far infrared irradiation devices of plurality of specifications (size, shape) can be made,
When selecting irradiation devices 1, it is desirable that the focal size irradiation devices 1 as matched as possible of selection and patient.Such as focal size
For the square region of approximate 5*3cm, then the rectangular irradiation devices of 8*5cm can be selected, or, focal size is approximate straight
The border circular areas of diameter 3cm, then the round irradiation devices of diameter 5cm can be selected.The control module and human-computer interaction device 4
Connection, human-computer interaction device 4 is used to send the mobile control signal of driving mechanical arm 11 to control module, to control mechanical arm 11
It is moved to different location, irradiation devices 1 are set to the mobile terminal of mechanical arm 11, and such irradiation devices 1 can have in its movable direction
Standby certain extendable room, mechanical arm 11 are connect by controlling lead with human-computer interaction device 4, and human-computer interaction device 4 can pass through
Control the mobile terminal running fix in three-dimensional space of lead control mechanical arm 11, it in this way can be for different patients or patient
Different lesions realize accurately targeted therapy.
As shown in Fig. 2, the tumor thermotherapy equipment further includes the first infrared thermal imagery connecting with the human-computer interaction device 4
Sensor 231 and its corresponding infrared data analyzing software system, according to a preferred embodiment of the present invention, described first is red
Outer thermal imagery sensor 231 is set to the mobile terminal of the mechanical arm 11, can acquire target object lesions position by the far infrared
The local surface temperature distributed intelligence of radiation, and the local surface temperature distributed intelligence is sent to the human-computer interaction device
4, the temperature distribution information is exported on the display 41 in human-computer interaction device 4 by human-computer interaction device 4, to realize
Monitoring and regulation to target object thermotherapy position local surface temperature.Wherein the acquisition target object is by the Far-infrared spoke
The local surface temperature distributed intelligence penetrated can be acquisition in real time, or interval acquisition or both collocation uses, Ke Yigen
It is configured according to actual conditions.The infrared data analyzing software system can be adopted based on the first infrared thermal imagery sensor 231
The surface temperature distribution information inference of collection goes out the three dimensional temperature distributed intelligence of corresponding region, and by the three dimensional temperature distributed intelligence
It is sent to the human-computer interaction device 4, is exported the temperature distribution information in human-computer interaction device 4 by human-computer interaction device 4
In display 41 on, to realize monitoring and regulation to target object thermotherapy position partial 3 d temperature.Such as when described
It is low by the local surfaces or three dimensional temperature of far infrared radiation that first infrared thermal imagery sensor 231 collects target object lesions position
When predetermined temperature, temperature information of the human-computer interaction device 4 according to feedback, regulation power module 3 increases in irradiation devices 1
The input electric power of the radiating element of setting improves its radiation temperature and radiation intensity, and then improves target object lesions position
Local surfaces or three dimensional temperature.
As shown in figures 1 and 3, according to a preferred embodiment of the present invention, the tumor thermotherapy equipment further includes irradiation
Bed 2, the irradiation bed 2 can be fixed or movable irradiation bed, can connect with the human-computer interaction device 4, and can be in institute
State under the control of human-computer interaction device 4 vertically and/or left and right and/or front-rear direction it is mobile.One according to the present invention preferably
Embodiment is also provided at least one in the inside of the mattress 21 as shown in figure 4, the irradiation bed 2 may also include mattress 21
A far infrared radiation unit (will be discussed in more detail below), specifically, the mattress 21 include mattress cotton layer, mattress cotton layer
In be provided with the array apparatus being made of at least one far infrared radiation unit, at least one far infrared radiation unit difference
It is connect with power module 3, that is to say, that power module 3 can be individually for each progress at least one far infrared radiation unit
Power supply.Wherein, the far infrared radiation unit gives off the similar far infrared of far infrared wave length with human body itself radiation, right
Lesions position carries out targeting radiation, generates efficient RESONANCE ABSORPTION, realizes better therapeutic effect.One according to the present invention
Preferred embodiment, far infrared radiation unit are small size unit.That is, graphene far infrared radiation array apparatus is embedded in
In the interlayer of mattress, it is fabricated to graphene far infrared radiation mattress, when patient is lain on the mattress, 4 basis of human-computer interaction device
The geometrical characteristic and lesion of patient's lesions position control different far infrared radiation units in mattress with respect to the spatial position of mattress
Working power on-off, obtain the Net long wave radiation region that the geomery of geomery and lesion matches, and and mechanical arm
Irradiation devices 1 on 11 match, to enhance therapeutic effect.
Wherein, power module 3 is connect with human-computer interaction device 4, and human-computer interaction device 4 is for controlling the difference of power module 3
For the power supply of far infrared radiation unit, power module 3 receives the instruction from human-computer interaction device 4, adjusts far infrared radiation unit
Operating current or operating voltage, to control the input electric power of far infrared radiation unit, to control far infrared radiation list
The far infrared radiation intensity of member, and by information such as the operating current of irradiation devices 1, operating voltages, feed back to human-computer interaction device
4.It is worth noting that 4 controllable power module 3 of human-computer interaction device is all lists at least one far infrared radiation unit
Member is powered, and can also control power module 3 is that the unit at least one far infrared radiation unit is powered, in this way
For the different lesions of different patients or patient, different far infrared radiation units is may be selected as heat source in human-computer interaction device 4,
The far infrared radiation unit for being combined into different Net long wave radiation shapes treats lesion, realizes accurately targeted therapy.
As shown in figure 5, according to a preferred embodiment of the present invention, being arranged in the irradiation devices 1 and the irradiation bed 2
Far infrared radiation unit include radiation diaphragm 121, the radiation diaphragm 121 is for irradiating the target treatment area where tumour
Domain.It radiates diaphragm 121 and is equipped with electrode 122, electrode 122 is connect by contact conductor with power module 3.According to the present invention one
A preferred embodiment, the radiation diaphragm 121 are graphene far infrared radiation film.I.e. far infrared radiation unit uses graphene
Far infrared radiation film is equipped with electrode 122 on film, and contact conductor one end is connect with electrode 122, the other end and power module
3 connections.As shown in fig. 6, irradiation devices 1 are the array apparatus of at least one far infrared radiation unit composition, wherein in array
Each far infrared radiation unit is individually controlled by power module 3, each far infrared radiation unit can be by power supply mould
Individually control becomes the cell arrangement to work independently to block 3, and the unit in such array may be combined to form different Net long wave radiation shapes
Shape.According to a preferred embodiment of the present invention, it can be controlled different in irradiation devices according to the geometrical characteristic of patient's lesions position
Far infrared radiation cell operation (i.e. the Net long wave radiation regions of irradiation devices), to form the geometric form to match with lesions position
Shape realizes orientation to lesions position, accurate radiation therapy.In this way, reaching same balance temperature under identical radiating condition
Degree, patient's area of irradiation area is smaller, and the time that can bear is longer, and therapeutic effect is better.Alternatively, identical radiating condition
Under, same irradiation duration is born, patient's area of irradiation area is smaller, and the attainable equilibrium temperature of institute is higher, treatment
Effect also can be more preferable.
As shown in figure 5, according to a preferred embodiment of the present invention, the tumor thermotherapy equipment further include: for detecting spoke
The temperature sensor 5 of 121 temperature of diaphragm is penetrated, temperature sensor 5 is set to radiation 121 on piece of diaphragm, for real-time or interval inspection
The surface temperature of bolometer film piece 121 feeds back to human-computer interaction device by the wired or wireless temperature information that will test that connects
4, to indicate the far infrared radiation intensity of radiation diaphragm 121.I.e. temperature sensor 5 can detect the operating temperature of film and feed back to
Human-computer interaction device 4, human-computer interaction device 4 control the on-off of thin film work power supply according to the temperature information of feedback.Wherein, warm
Degree sensor 5 can be thermistor, thermocouple etc..
As shown in Figures 2 and 3, according to a preferred embodiment of the present invention, the irradiation devices 1 further include: for examining
The safe distance detection module 123 of distance, safe distance detection module 123 and people between bolometer film piece 121 and target object
Machine interactive device 4 connects, and safe distance detection module 123 includes depth transducer and/or time-of-flight sensor and/or overflows anti-
Penetrate formula photoelectric sensor and its corresponding Data Analysis Software system.Wherein, target object is barrier, especially the body of patient
Body region.Contactless safe distance detection module 123 is additionally provided on irradiation devices 1, for detecting irradiation devices 1 and patient
Between distance information, safe distance detection module 123 connect with human-computer interaction device 4, will be examined by wired or wireless connection
The range information is exported by human-computer interaction device 4 and is filled in human-computer interaction to human-computer interaction device 4 by the distance information transmission of survey
It sets on the display 41 in 4, to indicate the degree of closeness between irradiation devices 1 and human body or barrier.Preferably, safety away from
Output signal from detection module 123, meeting synchronous feedback to mechanical arm 11.
As shown in fig. 7, according to a preferred embodiment of the present invention, the irradiation devices 1 further include: with power module 3
The luminous intensity of VISIBLE LIGHT EMISSION device 124 is adjusted in the VISIBLE LIGHT EMISSION device 124 of connection, power module 3, it is seen that light emitting
Device 124 is set at least one far infrared radiation unit and is formed by geometrical characteristic position.Specifically, power module 3 is being adjusted
The operating current of section radiation diaphragm 121 perhaps operating voltage while will react the electric work of the electric current or voltage swing
Rate is loaded on VISIBLE LIGHT EMISSION device 124, to control its luminous intensity, to intuitively indicate the remote red of radiation diaphragm 121
External radiation intensity.That is, being set at the geometrical characteristic position for the array apparatus that at least one far infrared radiation unit is formed
There are several VISIBLE LIGHT EMISSION devices 124, and the visual intensity that VISIBLE LIGHT EMISSION device 124 issues is controllable.Wherein, at least one
Any regulars or the irregular geometry such as the geometrical characteristic that a far infrared radiation unit is formed can be square, rectangle, circle
Figure.Wherein, as shown in fig. 7, at least one far infrared radiation unit of work forms circle, it is seen that light emitting devices 124 exists
It radiates and forms circle on diaphragm 121.Similarly, as shown in figure 8, far infrared radiation unit formed it is rectangular, at this moment VISIBLE LIGHT EMISSION fill
Set 124 radiation diaphragm 121 on formed it is rectangular.Since infrared ray is black light for human eye, for real-time monitoring pair
When patient carries out radiant heating, the precise area of raying part and the radiation intensity of far infrared, in far infrared radiation unit shape
At geometrical characteristic location arrangements VISIBLE LIGHT EMISSION device 124.In this way, opening visible light during mobile irradiation devices 1
Emitter 124 can intuitively and accurately judge that patient is irradiated by the visible light spot of observation irradiation on a patient body
The specific location that device 1 radiates.By observation patient body on visible light spot bright dark degree, can intuitive judgment go out irradiate dress
Set 1 radiation intensity.
According to a preferred embodiment of the present invention, mechanical arm 11 includes: the driving motor connecting with control module, and
The mechanical arm connecting with driving motor, irradiation devices 1 are set to the mobile terminal of mechanical arm 11.Control module, which receives, comes from man-machine friendship
The space orientation instruction that mutual device 4 is sent, while acquiring each sensor (such as encoder/angle/acceleration/close to switch)
Feedback information completes closing to 1 spatial position of irradiation devices of 11 mobile terminal of mechanical arm to control the driving motor of mechanical arm 11
Ring control.Preferably, mechanical arm 11 can receive feedback information, safe distance detection module 123 from photopic vision module 7
Feedback information, with ensure the safety between mechanical arm and fixed irradiation devices 1 and other target objects at its end away from
From.
As shown in Figure 1, according to a preferred embodiment of the present invention, the irradiation bed 2 further include: three-dimensional is supported to move
Dynamic bedstead 22, bedstead 22 are connect with human-computer interaction device 4.Under the control of human-computer interaction device 4, bedstead 22 liftable peace
It moves, to control the running fix of mattress 21 in three-dimensional space.
As shown in Figures 2 and 3, according to a preferred embodiment of the present invention, the tumor thermotherapy equipment further includes and institute
The the second infrared thermal imagery sensor 232 and its corresponding infrared data analyzing software system of the connection of human-computer interaction device 4 are stated, it is described
Second infrared thermal imagery sensor 232 may be disposed at any position, such as may be disposed at 1 position of irradiation devices with mechanical arm one
Rotation is played, also can be set in the side of the irradiation bed 2, can also be fixedly installed at a certain position, for acquiring target pair
The overall surface temperature distribution information of elephant, and the temperature distribution information is sent to the human-computer interaction device 4, by man-machine friendship
Mutual device 4 exports the temperature distribution information on the display 41 in human-computer interaction device 4, to realize to target object
The on-line monitoring of overall surface temperature.
As shown in Figure 2 and Figure 9, according to a preferred embodiment of the present invention, tumor thermotherapy equipment further include: clinical thermometer
6, for real-time detection body temperature and feed back to human-computer interaction device 4.Clinical thermometer 6 passes through wired or wireless way and man-machine friendship
Mutual device 4 connects.The clinical thermometer 6 be contact clinical thermometer, for detect patient's privileged site (such as rectum, inner ear, it is sublingual,
Oxter etc.) point temperature information, contact clinical thermometer connect with human-computer interaction device 4, will test by wired or wireless connection
Temperature information be transmitted to human-computer interaction device 4.
As shown in Figures 2 and 3, according to a preferred embodiment of the present invention, the tumor thermotherapy equipment further include: visible
Light vision module 7, it is seen that light vision module 7 includes: the video camera connecting with human-computer interaction device 4, is regarded for acquisition camera
The relative space position of target in the range of field, and feed back to human-computer interaction device 4.
According to a preferred embodiment of the present invention, the tumor thermotherapy equipment further include: analysis of image data software systems,
For determining the relative position information between the collected target of photopic vision module 7.Wherein, target include: irradiation devices,
At least one of in target patient, irradiation bed, mechanical arm and other undefined targets etc..Analysis of image data software systems will
The image of photopic vision module 7 exports on the display 41 in human-computer interaction device 4, and marks out by analysis of image data
Relative space position information between the calculated different target of software.Preferably, relative space position information can also synchronize instead
It is fed to mechanical arm.
According to a preferred embodiment of the present invention, it is seen that light vision module is by the spatial position of irradiation devices 1 and patient
Information feeds back to human-computer interaction device 4 with visible light view, and the second infrared thermal imagery sensor 232 is by the infrared view of the entirety of patient
Human-computer interaction device 4 is fed back to, infrared view and visible light view are overlapped presentation by human-computer interaction device over the display, operation
Personnel can indicate patient on view and need to carry out spoke according to the visible light view and infrared view information that show on display
Penetrate the target area for the treatment of.The target area that human-computer interaction device 4 is indicated according to operator sends positioning coordinate to mechanical arm
Instruction, determines that mechanical arm is moved to specific position.In addition, human-computer interaction device refers to also according to target area to power module sending
It enables, the far infrared radiation unit in irradiation devices and mattress is controlled by power module and forms the effective spoke to match with target area
Region is penetrated, target hyperthermia is carried out to lesions position.
The key of tumor thermotherapy is to control the thermotherapy dosage of target area.Thermotherapeutic agent amount depend on thermotherapy when treatment temperature and
Treatment time, temperature is too low, the time is too short, causes thermotherapy underdosage, does not serve, but temperature is excessively high, overlong time, again
Patient may be caused to damage.The thermotherapy dosage of control target area includes that temperature detection and temperature control two aspects.One is warm
Degree detection, damages one kind that thermometry is temperature detection, i.e., temp probe is inserted into tissue and carries out thermometric, belong to direct survey
Temperature, temperature data is accurate, time delay is small, but disadvantage is that side effect is obvious, and in order to reduce damage, mostly single-point thermometric；Also
A kind of temperature detection is the surface temperature based on target area, infers the Temperature Distribution of target area, belongs to indirect thermometric, disadvantage is temperature
Poor reliability, the time delay of degree evidence are big.The second is temperature controls, a kind of method be control target area tissue temperature it is constant, it is this
Method is likely to occur the high thermal damage of normal tissue and skin, and another method is the temperature of control heater (heat source), rather than
The temperature of human body heated part, this method cannot ensure that human body heated part reaches optimal treatment temperature, or even has and burn
Risk.
As shown in figure 9, according to a preferred embodiment of the present invention, the human-computer interaction device 4 of the tumor thermotherapy equipment
Further include: temperature control system 42, temperature control system 42 are supported: in conflicting model, constant temperature mode and impact constant temperature alternate mode extremely
A kind of few temperature controlling mode.Several temperature controlling mode is set in human-computer interaction device 4, and operator selects one of temperature control
After mode, temperature controlling mode of the human-computer interaction device 4 according to selection, surface and/or three dimensional temperature in conjunction with patient's raying position
Distributed intelligence, the overall surface temperature distribution information of patient, the body temperature information of patient and graphene far infrared irradiation devices
Work state information adjusts the input electric power of graphene far infrared irradiation devices, realizes to patient's raying spot temperature
Closed-loop control controls surface and/or three dimensional temperature distribution parameter (region maximum temperature, minimum temperature, the mean temperature at the position
Deng) it is target set point.
As shown in Fig. 2, Fig. 3 and Fig. 9, according to a preferred embodiment of the present invention, human-computer interaction device 4 further include: fixed
Position system 43, positioning system 43 be used to determine the targeted treatment area of patient, as the spatial position of target object, region shape and
Size.
Wherein, above-mentioned human-computer interaction device 4 can be computer, specifically can also include: display 41, touch screen, key
Disk and mouse.
The tumor thermotherapy equipment of the embodiment of the present invention provides steady by least one far infrared radiation unit as heat source
The similar far infrared of far infrared wave length fixed, with human body itself radiation, carries out targeting radiation to lesions position, generates efficient
The RESONANCE ABSORPTION of rate realizes better thermotherapy effect.In addition, the tumor thermotherapy equipment is also by by least one far infrared radiation
Array apparatus, mechanical arm, the VISIBLE LIGHT EMISSION device of unit composition carry out auxiliary positioning, safe distance detection and photopic vision
Etc. combining, accurately targeted therapy is realized to focal area.And further passes through contactless infrared thermal imagery sensor, connects
Touch clinical thermometer, contact type temperature sensor etc. combine, and are accurately controlled the temperature of focal area, and with different temperature
Control mode carries out temperature control, it is ensured that lesion obtains expected thermotherapy dosage.
Finally, it should be noted that the foregoing is only a preferred embodiment of the present invention, it is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features.
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention
Within protection scope.
Claims (12)
1. a kind of tumor thermotherapy equipment, comprising: irradiation devices, power module and human-computer interaction device, which is characterized in that the spoke
Include at least one far infrared radiation unit according to device, at least one described far infrared radiation unit respectively with the power module
Connection；
Wherein, the power module is connect with the human-computer interaction device.
2. tumor thermotherapy equipment according to claim 1, which is characterized in that further include:
With the first infrared thermal imagery sensor and its corresponding infrared data analyzing software system of human-computer interaction device connection；
And/or further include mechanical arm, the irradiation devices are set to the mobile terminal of the mechanical arm；Preferably, the irradiation dress
It sets and is detachably connected with the mechanical arm；
Preferably, the first infrared thermal imagery sensor is set to the mobile terminal of the mechanical arm, for acquire target object by
The local surface temperature distributed intelligence of the far infrared radiation, and the temperature distribution information is sent to the human-computer interaction and is filled
It sets；Preferably, the acquisition is acquisition in real time or interval acquisition.
It is further preferred that the infrared data analyzing software system, is based on the surface temperature distribution information, derive corresponding
The three dimensional temperature distributed intelligence in region, and the three dimensional temperature distributed intelligence is sent to the human-computer interaction device.
3. tumor thermotherapy equipment according to claim 1, which is characterized in that it further include fixed or movable irradiation bed,
Preferably, the irradiation bed is connect with the human-computer interaction device, and under the control of the human-computer interaction device vertically and/
Or front and back and/or left and right directions move；
Preferably, the irradiation bed includes: at least one far infrared radiation unit, at least one described far infrared radiation unit point
It is not connect with the power module；It is further preferred that the irradiation bed includes: mattress, at least one described infra-red radiation list
Member is set to the inside of the mattress.
4. tumor thermotherapy equipment according to claim 1-3, which is characterized in that the far infrared radiation unit packet
Radiation diaphragm is included, the radiation diaphragm is equipped with electrode and temperature sensor, and the electrode passes through contact conductor and the power supply
Module connection, the temperature sensor acquire the temperature information of the radiation diaphragm, and the temperature information are sent to described
Human-computer interaction device；
Preferably, the far infrared radiation energy of the radiation diaphragm concentrates on 4~14um wave band, and radiation peak wavelength is 8~
10um；Preferably, the radiation diaphragm includes graphene film；It is further preferred that the graphene film is CVD method preparation
Graphene film.
5. tumor thermotherapy equipment according to claim 1, which is characterized in that further include:
Clinical thermometer, the temperature information of the specific region for acquiring target object, and the temperature information is sent to the people
Machine interactive device；Wherein, the clinical thermometer is connect by wired or wireless way with the human-computer interaction device；
And/or the tumor thermotherapy equipment further include:
The the second infrared thermal imagery sensor and its corresponding infrared data analyzing software system connected with the human-computer interaction device,
The man-machine friendship is sent to for acquiring the overall surface temperature distribution information on target object, and by the temperature distribution information
Mutual device, it is preferable that the infrared data analyzing software system is based on the surface temperature distribution information, derives respective area
The three dimensional temperature distributed intelligence in domain, and the three dimensional temperature distributed intelligence is sent to the human-computer interaction device；
And/or the tumor thermotherapy equipment further include:
Photopic vision module, for determining between the irradiation devices and target object and/or the irradiation bed and target pair
Relative space position information as between, and the relative space position information is sent to the human-computer interaction device；It is preferred that
Ground, the photopic vision module include visible light camera and its corresponding analysis of image data software systems.
6. tumor thermotherapy equipment according to claim 1, which is characterized in that the irradiation devices further include:
The safe distance detection module being connect with the human-computer interaction device, for detect the irradiation devices and target object it
Between range information, and the range information is sent to the human-computer interaction device；Preferably, the safe distance detects mould
Block includes depth transducer and/or time-of-flight sensor and/or diffusing reflection formula photoelectric sensor and its analysis of corresponding data
Software systems；
And/or the irradiation devices further include:
The VISIBLE LIGHT EMISSION device connecting with the power module, the VISIBLE LIGHT EMISSION device are set to that described at least one is remote
Infrared radiation unit is formed by geometrical characteristic position, for intuitively indicating radiation iris action in the far infrared of target object
Radiation areas and radiation intensity；Preferably, the power module, will while adjusting the radiation diaphragm input electric power
Indicate that the electrical power of the electrical power size is loaded into the VISIBLE LIGHT EMISSION device, enough to control the VISIBLE LIGHT EMISSION device
Luminous intensity, the electrical power of the far infrared radiation unit be a far infrared radiation unit electrical power or multiple Far-infrared spokes
Penetrate the average value of the electrical power of unit.
7. tumor thermotherapy equipment according to claim 1, which is characterized in that the human-computer interaction device further include: interaction
Interface；
And/or the human-computer interaction device further include: temperature control system, the temperature control system are supported: conflicting model, constant temperature mode
And at least one of impact constant temperature alternate mode temperature controlling mode.
8. a kind of control method of tumor thermotherapy, which is characterized in that the control method includes:
Determine spatial position and the shape size information of the targeted treatment area that target object needs far infrared radiation to treat；
According to the spatial position and shape size information, the space phase between irradiation devices and the targeted treatment area is adjusted
To position；
Set temperature controlling mode；
Power module starts, and the far infrared radiation cell operation to match on irradiation devices with targeted treatment area simultaneously radiates target
Treatment region, and/or, it irradiates the far infrared radiation cell operation to match in bed with targeted treatment area and radiates goal treatment
Region；
Real-time or compartment of terrain obtains the temperature distribution information of targeted treatment area；With
According to pre-selected temperature controlling mode and the temperature distribution information of the targeted treatment area, the irradiation devices are adjusted
And/or irradiate the input electric power of at least one far infrared radiation unit in bed.
9. the control method of tumor thermotherapy according to claim 8, which is characterized in that the determining target object needs remote
The step of spatial position of the targeted treatment area of infra-red radiation treatment and shape size information, comprising:
It obtains the temperature distribution information of target object entirety and is showed on the interface of human-computer interaction device；
According to the temperature distribution information, treatment region is selected on human-computer interaction device interface, determines that the target object needs
The spatial position for the targeted treatment area for wanting far infrared radiation to treat and/or shape size information.
10. the control method of tumor thermotherapy according to claim 8, which is characterized in that according to the spatial position and shape
Shape size information, the step of adjusting the relative space position between irradiation devices and the targeted treatment area, comprising:
According to the spatial position of the targeted treatment area and shape size information, positioning is sent to mechanical arm and/or irradiation bed
Signal, to adjust the relative space position of irradiation devices Yu the targeted treatment area.
11. the control method of tumor thermotherapy according to claim 8, which is characterized in that the temperature controlling mode includes: impact
At least one of mode, constant temperature mode and impact constant temperature alternate mode.
12. the control method of tumor thermotherapy according to claim 8, which is characterized in that the real-time or compartment of terrain obtains
The temperature distribution information of targeted treatment area, comprising:
Target object is obtained by the local surface temperature distributed intelligence of far infrared radiation；
According to the surface temperature distribution information, the three dimensional temperature distributed intelligence of corresponding region is derived.
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