WO2008002175A1 - Weekly diet food package for oncological patients and for long-living persons - Google Patents

Abstract

The invention relates to medicine. The inventive weekly diet food package for oncological patients and for long-living persons comprised food products used at the following component ratio in grams: 205-210 dog-rose flour, 340-350 buckwheat, 65-70 shorts, 32-35 green tea, 980-1000 coarse bread, 190-200 beans, 190-200 lentil, 290-300 shiitake mushrooms or fresh maitake mushrooms and 145-150 dried mantakes, 290-300 fresh salmon, 140-150 non-incubator chickens, 190-200 common onion, 90-95 garlic, 1450-1500 carrots, 1450-1500 tomato, 450-500 green head cabbage, 450-500 Brussels sprout, 450-500 cauliflower, 290-300 broccoli, 470-500 beetroot, 340-350 not hot pepper (red,yellow, green), 18-20 celery, 18-20 dill, 18-20 parsley, 18-20 wormwood, 380-400 blackberry, 380-400 grape, 2600-2700 pineapple, 2400-2450 papaya, 240-250 lemon, 260-270 orange ans 340-350 olive oil.

Description

 A set of products for a weekly diet for cancer patients and long-livers

The invention relates to medicine, and specifically to oncology and gerontology, and relates to a diet proposed for the treatment of cancer patients, in addition, it can be successfully used for centenarians.

Oncological diseases affect a lot of people, and all over the world. Unfortunately, the incidence of cancer has a positive trend: about 5 million people die of cancer every year in the world, and 9 million patients who first have malignant neoplasms face a difficult survival task (Kruglyak L.G. Rational nutrition in cancer, St. Petersburg: IG "BEC", 2004, p.6).

Despite significant advances in the diagnosis and treatment of malignant neoplasms, the expansion of the network of specialized medical institutions, cancer mortality remains quite high. So in

In Russia in 2000, 13.9% of men and 13.6% of women died from various forms of cancer

(Kruglyak L.G., ibid., P. 6).

The creation of new powerful drugs, new methods of radiation and surgical treatment of tumors, unfortunately, does not yet fully cure cancer, but only makes it possible to extend the patient's life.

The efforts of a large group of scientists and practitioners are aimed at creating the perfect medicine that would target the tumor without affecting healthy organs and tissues. But until today, taking into account the achievements of modern technology, it is not possible to obtain such a substance. Widespread use of radiation therapy, chemotherapy or extensive surgical interventions give the patient even more suffering than the malignant tumor itself.

600 thousand women die every year from breast cancer. Many of them could be saved. The problem is that without a healthy and healthy immune system (and it is unhealthy, once the body is sick), recovery is impossible (Laskin V.A. Second birth, St. Petersburg, “Gepepash”, p.3, 2002).

In recent years, progress in the treatment of breast cancer (breast cancer) has been associated with the widespread use of complex treatment, including locoregional (operative radiation) and systemic effects (chemotherapy). It is known that radiation therapy, surgical treatment and chemotherapy have a damaging effect on all body systems and, first of all, on the hematopoietic system, immune system (IS), the gastrointestinal tract, cardiovascular and nervous systems, etc.

Radiation therapy and chemotherapy are nonspecific and damage not only tumor cells, but also normal, actively proliferating cells, including immunocompetent ones. Cytostatics contribute to the radical “knocking out” of a lymphocyte clone (LF) activated to a specific antigen, disrupting an initially defective immune defense. In some cases (IP) it is so suppressed that the ability to independently restore the immune response (AI) does not appear even after a break in treatment. At the end of chemotherapy courses according to the SMF scheme, the total number of LF in the blood decreases by 50% of the initial number, CD4 cells by 60%, the immunoregulatory index (IRI) drops to 1.5 and remains at this level for 2-3 years.

Radiation therapy also has an immunosuppressive effect. The suppression of humoral and cellular immune responses is accompanied by an increased risk of dissemination of an existing tumor, the emergence of new malignant neoplasms, and superinfection. The myelodepressive effect of cytostatics complicates the specific treatment, makes it necessary to reduce single and total doses of drugs, prescribe expensive colony-stimulating factors. Antitumor agents of various classes and mechanism of action, radiation therapy induce staged in the patient's body changes in antioxidant activity (AOA) of lipids and have one common feature: at one stage or another they reduce the level of antioxidant reactions.

One of the mechanisms for the development of side effects of chemoradiotherapy is the formation of free radicals. Their excessive accumulation contributes to damage to the membranes of not only tumor cells, but also normal cells, causing serious metabolic disturbances in them, leading to functional failure of various organs. As a result, the quality of life of patients worsens, the development of severe toxicosis is observed, there is a need to interrupt treatment, which ultimately affects its effectiveness.

Therefore, the search for new ways to protect the body from the damaging effects of complex treatment (breast cancer) remains relevant. One of such ways is the use of biologically active additives (BAA) after radiation therapy, for example, “BIOCKAH C”. This dietary supplement is a natural product extracted from Siberian larch wood. The main component of dietary supplement is bioflavonoid-dihydroquercytin. The total content of active substances in the dietary supplement is at least 90%. The specified flavonoid is one of the strongest natural antioxidants, which causes a wide range of biochemical activity of “BIOCKAH C”. A known method of corrective therapy for the complex treatment of breast cancer, including the appointment of biologically active additives "BIOCKAH C" two days before the start of chemotherapy at a dose of 10-15 ml twice a day, and before the start and during chemotherapy, the indicators of the number of leukocytes in blood and transaminase levels and with a decrease in the number of leukocytes to 3, 3xlO ³ / L - 3.0xl0Vl and / or an increase in the level of transaminases by 1.5-2 times compared with the norm, the dose of “BIOCKAH C” is doubled, while the biologically active additive “ BIOCKAH C "breed 0.9% f isological solution (patent RU N ° 2223779, IPC 7 A 61 K 35/78, A 61 B 5/145, A 61 P 35/00, 2002).

Using the proposed method made it possible to improve the quality of life of patients, as well as to correlate the immune dysfunctions and metabolic disorders that took place and to ensure the full conduct of PCT courses. It is also known that all tumors, both malignant and benign, are formed against the background of an imbalance in the acid-base balance of the body, and in accordance with this they are divided into two groups: - tumors formed against the background of strongly alkaline blood pH and tumors formed on background strongly acidic blood pH. In this regard, many therapeutic agents have been developed, protected and used, depending on the patient's affiliation with the said groups.

The most interesting is a universal remedy with antitumor effect, providing _. normalization of the acid-base balance of the body, containing knotweed (birdlance) grass, dioica nettle grass, field horsetail grass, marshmallow roots, barberry grass, Chernobyl grass, five-lobed motherwort grass, valerian grass roots, grasshopper grass, wild roots, porcini mushroom, mummy, bear bile, forgotten roots, common caraway seeds, linden flowers, lingonberry leaves, medicinal verbena grass, grass of the uterine uterus (one-sided ortilia), common rhizome grass, anise seeds go, pink periwinkle grass, goose cinquefoil (whole plant), angelica roots, common flax grass, saber-eared marsh roots, high root roots, birch buds, ordinary hop cones, medicinal drop letters, orthosiphon grass (Japanese tea bud), flowers , grass of the large celandine, spring primrose flowers, leaves of blackberry gray, leaves of large-leaved pear, grass of the common blueberry, grass of the white-leaved marsh, grass of the Astragalaceae, seeds of garden dill, grass efe core, licorice roots with the appropriate ratio of components (patent of the Russian Federation Na 2180232, MPK7 A 61 K 35/78, 2001).

In recent years, in the practice of treating cancer, the use of numerous phytocomplexes prepared on the basis of a wide range of medicinal plants has become very widespread.

Known phytocomplex for the prevention and treatment of cancer patients, which is an infusion of medicinal plants, obtained on the broth of medicinal plants. For the broth, they take in specified ratios St. John's wort perforated, leaves of wild strawberry, flowers of meadow clover, prickly thistle, horsetail field, elecampane tall, narrow-leaved fireweed leaves. For infusion, in accordance with the collection of medicinal plants taken for decoction, they take in the given proportions the inflorescences of tansy ordinary, sweet clover, common wormwood, motherwort five-lobed, flowers of marigold medicinal, mint field, celandine big, oregano, marsh rosemary, mother-and- stepmother, drooping birch, dioica nettle or marigold flowers, motherwort five-lobed, medicinal melissa, hawthorn blood-red, yarrow, chamomile, large celandine, common wormwood , white mistletoe, large plantain, immortelle sandy (patent RU Xa 21 b 1979, IPC 7 A 61 K 35/78, 1999)

The proposed phytocomplex provides an increase in the protective ability of the body and is used to treat various diseases, including breast cancer. At the same time, there are known difficulties with the preparation and production of environmentally friendly plants, the preparation and dosage of the necessary decoctions and infusions, possible side effects, as well as the need to prescribe diet food during the course of treatment.

Environmental pollution, excessive consumption of synthetic drugs and preservatives that humans are not evolutionarily adapted to, as well as a lack of plant components containing natural antioxidants, antiallergens, antimutagens, and anticarcinogens, contribute to the growth of allergic, oncological, and especially liver and gastrointestinal diseases tract.

The main advantages of herbal preparations are their versatility and gentle effects on the body, the absence or insignificant side effect, and good tolerance to patients.

Disadvantages - a narrow spectrum of pharmacological action and the use of hard-to-reach components. The use of alkaloids of the genus Colchium with their rather high toxicity can lead to the development of serious complications - leukopenia and thrombocytopenia. When using the plant alkaloid as an antitumor agent, the periwinkle-rosewin (vinblastine) plant for the treatment of hematosarcoma and lymphogranulomatosis significantly inhibits leukemia and thrombopoiesis, causes weakness, loss of appetite, vomiting, jaundice. A known composition having antitumor, hepatoprotective and immunostimulating effects, including dry extract of hill hodgepodge grass, dry extract of chaga mushroom and dry extract of Kuril tea in the following ratio of components, wt.%: Dry extract of fungus mushroom 40-80, dry extract of Kuril tea 12, 5-37.5, dry extract of grass hodgepodge hill 7.5-22.5 (patent RU JVb 2221586, IPC 7 A 61 K 35/78, 2002)

Known means for the prevention and treatment of malignant neoplasms, which is an alcohol tincture of herbs with antitumor activity, and herbs that have a general strengthening effect on the body and stimulate the body's immune system and tone. The composition of the product includes: calamus marsh, marigold, rosehip, knotweed, immortelle, viburnum, marin root, St. John's wort, horsetail, pink periwinkle, blueberries, black currants, horse sorrel, black mulberries, celandine, hawthorn, medicinal comfrey, licorice, Chaga , cinquefoil erect and garlic (patent RU N ° 2044547, IPC 6 A 61 K 35/78, 1995).

Also known is a means for the prevention and postoperative treatment of malignant neoplasms, consisting of two tinctures and a decoction, which include: tincture 1 (alcohol) - angelica root, calamus root, ephedra grass and plantain grass; in tincture 2 (alcohol) - the root of the step, the root of the decopus and the grass of ephedra; in broth (distilled water) - chaga, wild rosemary, St. John's wort, immortelle sand, calendula, elecampane root, blueberry leaf, knotweed, horsetail, plantain, chicory, rose hips and bee honey (patent RU Na 2027441, IPC 6 A 61 K 35 / 78, 1995).

Another analogue can be noted - a phytopreparation, which is prepared from medicinal mushrooms and plants containing karyoclastic poisons (patent RU Ns 2074731, IPC 6 A 61 K 35/78, 1997).

The disadvantage of all these compositions is the high toxicity of herbal medicines based on karyoclast poisons, which act not only on atypical cells, but also on the whole organism. In this regard, the main task when using the compositions described above is to reduce the harmful effects of karyoclastic plant poisons on healthy tissues of the body, while maintaining and strengthening them effects on malignant neoplasms, as well as strengthen the effect of x-ray therapy and chemotherapy with a decrease in their dosage, which does not reduce the effectiveness of the therapy, to prevent the development of leuko- and thrombocytopenia, metastasis and relapse in the postoperative period. In accordance with this invention, at the same time as the main phytopreparation, a dose of deoxyribonucleic acid and antitumor phytopreparations are administered, as well as additionally antitoxic and / or antianemic and / or tonic and / or antihistamine and / or immunomodulating and / or diuretic drugs herbal remedies. The main phytopreparation is prepared from phyto-collection, which includes medicinal plants and mushrooms in the following ratio of components by weight: corm seeds of Colchicum autumn 2-60, Colchicum vulgaris 2-60, Pedophilus thyroid (resin rhizomes) 20-40, gorinik Russian 200 - 400, pink periwinkle 100–200, spotted hemlock 1–20, Dzhungarian aconite 1–20, large celandine 2–60, dipelia 20–60, small-leaf burser 100–200 fly agaric, 200–600 red fly agaric, 100–200 long-legged talker, honey agaric winter 100 - 200, thick pig 100 - 200, giant raincoat th 60-100.

An antitumor herbal preparation is prepared from a phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: plantain 4-6, cornstalk 2-6, cornflower stalk 1-2, narrow-leaved 1-2, field horsetail 2-6, Chaga 6 - 10, purifications purple 2 - 4.

An antitoxic phytopreparation is prepared from phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: milky-flowered peony 1 - 8, Chinese remany 1 - 8, poria coconut 1 - 8, atractylodes ovoid 1 - 2, Ural licorice 1 - 2 .

An antianemic herbal preparation is prepared from a phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: nippon dioscorea 10–20, yellow red 1–3, cornflower stalk 1–5, Pacific frangipani 10–40, fragrant nippon 1–1 3, Scutellaria baicalensis 20–40, Chinese romania 10–30, St. John's wort perforated 10–30. A tonic phytopreparation is prepared from phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: real ginseng 10–50, asterisk 10–50, bird highlander 10–50, prickly eleutherococcus 5–10, pink rhodiola 5–10 , Himalayan rhododendron 1–3, Chinese magnolia vine 1–3, heart-shaped aralia 1–3, aloe 5–30, pakhima cholean 5–30.

An antihistamine phytopreparation is prepared from phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: Ural licorice 5 - 10, evasive peony 10 - 30, Indian colosant 1 - 3, Baikal skullcap 10 - 30.

A diuretic phytopreparation is prepared from a phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: tansy 1–5, Ural licorice 10–30, paper therapanax 1–5, field horsetail 10–30, St. John's wort perforated 10–30, hairy wormwood 1–3, Chernobyl 10–30, buds foliate 5–10, plantain large 10–40, nettle 1–10, mountaineer 10–30 (patent RU JN ° 2161040, IPC 7 A 61 K 35/78, A 61 P 35/00, 2000).

It was experimentally established that the introduction of normal high-polymeric deoxyribonucleic acid into the human body when interacting with the substances of the cell nucleus and, above all, with the DNA of the cell, leads to a partial replacement of DNA molecules of chromosomes or nuclei of tumor cells that have deviating structures from the norm.

Extracts of karyoclastic poisons, acting on tumors as mitotic poison, inhibit cell division in metaphase with sharp damage to cell nuclei and gluing of chromosomes, i.e. these poisons have a cytotoxic, anti-miotic, and in some cases inhibitory effect against atypical cancer cells. Cells of malignant tumors, which have a characteristic spindle-shaped shape, become rounded, and their cytoplasm and nucleus undergo changes (fragmentation, pycnosis), leading to atypical cells to death. During x-ray therapy, the simultaneous administration of a complex of karyoclastic poisons into the patient's body increases the radiosensitivity of tissues and the effectiveness of x-ray therapy, enhancing cytostatic and cytotoxic the effect of radiation due to the positive effect on the metabolism of amino acids (glycine, tyrosine, leucine, tryptophan, thionine) in inoperable cancer patients.

The action of karyoclastic poisons and medicinal plants is determined by the sum of biologically active substances contained in various parts of plants and fungi, the most important of which is colchicine and its derivatives - colchicerin, narcotine, and the amount of alkaloids.

Colchicine is effective in malignant neoplasms, a characteristic feature of which is intensive cell division. It affects the functional activity of cells, in particular, the release of prolactin and growth hormone by the functioning pituitary carcinoma cells, 2-3 times increases the intracellular concentration of prolactin and growth hormone, blocks the inhibitory effect of hydrocortisone on the accumulation of prolactin and growth hormones inside the cells. Colchicine and its derivatives are effective against lymphosarcoma and adenocarcinoma. The effectiveness of colchicine preparations increases if a drug collection is prescribed at the same time containing colchicine synergists: alkaloids with a stilbamine group - berberine, bulbocapnin, d-tubocurarine, vetrin, strychnine, papaverine, thebaine, corridine, laurotetaine, glaucine, aporfin, morphoteba. The mechanism of action of the drug containing these substances is as follows: there are two receptors for mitotic poisons in the cell; the binding of one of these receptors causes a cell division disorder, whereas when the second receptor binds, the process of cell division proceeds normally. The alkaloids bind the second receptor, as a result of which a large amount of colchicine binds to the first receptor, and the effect on mitosis is enhanced.

Muscle poisons of the strychnine type enhance the antimitotic effect by analogy with the chemistry of the cell spindle and muscles in the contracture phase. But since the spindle is still not completely identical to myofibrils, muscle poisons do not immediately act on it, their effect appears only after the spindle damaged by colchicine becomes even more similar to muscle fiber.

It is important to note that x-ray therapy increases the karyoclast effect of colchicine. Another biologically active substance contained in the plants of the medicinal phytosport used in the implementation of the claimed invention is colchamine (omain), which is 7-8 times less toxic than colchicine. Colchamine affects the metabolism of aminoxylot, normalizing it. When using colchamine, inhibition of glycine metabolism in the spleen and kidneys is more pronounced, tyrosine in the tissues of the brain and liver, leucine in the kidneys, tryptophan in the liver and spleen, methionine in the tissues of the liver, spleen and kidneys. Colchamine stimulates erythropoiesis somewhat. Plants used in treatment affect thiodisulfide metabolism, redox enzymes, and regulatory proteins of signal-transmitting receptor systems that control the metabolic processes and activity of the genetic apparatus of cells, mainly organs of immune and hematopoiesis. Under the influence of plant collections, immunomodulators have a differentiated effect on normal and pathologically altered cells (atypical and virus-modified), as a result of which the proliferation and differentiation of normal cells is stimulated along with the induction of apoptosis mechanisms in transformed cells. The compositions mentioned above are used as monotherapy in inoperable cases of the 3-4 stage of the disease and as an accompaniment to chemotherapy, radiological and surgical treatment.

In accordance with the trends of modern tumor chemotherapy, the introduction of the most tolerated doses of cytostatics is supposed, with the aim of the most complete damage to the tumor cells. However, the remaining fairly high toxicity of anticancer drugs is a serious limitation in achieving the maximum therapeutic effect. Liver dysfunction as a result of modern anti-tumor chemotherapy regimens develops in a significant number of patients. One of the currently widely used cytotoxic drugs is the cyclophosphamide (CF) alkylating agent. Many organic compounds undergo alkylation, but the determining factor is AND

DNA damage. The main side effects of cyclophosphamide are hematopoiesis, immunosuppression, and a hepatotoxic effect is also noted.

The main objective of this direction of the fight against malignant neoplasms is to expand the arsenal of products from plant materials, which simultaneously increase the antitumor activity of chemotherapy drugs and reduce their toxicity, in particular, hepatotoxicity.

An example of one of these solutions is the use of lohein as a means of increasing the antitumor and antimetastatic activity of cyclophosphamide (patent RU JCH 2225720, IPC 7 A 61 K 35/78, A 61 P 35/00, 35/04, 2002)

It is also known to use a wide range of drugs as agents for the prevention of cancer agents that normalize cell differentiation, apoptosis inducers and oncogen activation inhibitors (vitamin A, retinoids, sodium butyrate, vitamin D, perilyl alcohol, limonene, farnesyltransferase inhibitors); non-steroidal anti-inflammatory drugs (indomethacin, voltaren, aspirin, cyclooxygenase-2 inhibitors and lipoxygenase); carcinogen absorption, activation and detoxification modulators (calcium, phenethylisothiocyanate, indol-3-carbinol, ursodiol, oltipraz, N-acetylcysteine); epselon amino caproic acid); antioxidants (beta-carotene and other carotenoids, selenium, vitamin E, P-methoxyphenol and other flavonoids, butylhydroxyanisole); antiproliferative agents (alpha-difluoromethylornithine, dehydroepiandrosterone, fluasterone); modulators of hormonal balance and activity of growth factors (tamoxifen, exemestane, flutamide, finasteride, isoflavonoids); proofreaders of DNA methylation disorders (folic acid, methionine); cyclic nucleotides or inhibitors of phosphodiesterase activity (cyclic AMP, theophylline); immunomodulators (interferon and interferonogens, peptide preparations of the thymus and pineal gland) (Aleksandrov V.A. et al., Preclinical and clinical study of means for chemoprophylaxis of cancer, Handbook, St. Petersburg, Esculap, 1997, p. 32; Kelloff GJ. Reserves on sapper chemistry). Research Apd Drug Devolormpt, Adv. Sapser Res. 2000. Vol. 78, p. 199-334). All of these funds have significant limitations due to the presence of serious side effects and contraindications. Because they are obtained by chemical synthesis, then all synthetic agents, as a rule, have toxic side effects. In this regard, the increasing attention that in recent years, as noted above, has been given to natural products, extracts of food and medicinal plants, which for the most part usually do not have significant toxic effects and side effects, is explainable.

It can be noted about the use of ginseng extracts for the prophylaxis of cancer (Vesralov VG, et al. Chemorreptiop of mammarium, serpent aproposomp. (Suprl.) P.42-53).

Also known are complex cancer prevention products obtained from biologically active substances of brown seaweed: clamin, phytolone, fucus, as well as pine and spruce needles: pheocarpine (patent RU N ° 2031654).

The mentioned complex agents are practically non-toxic, have no side effects and contraindications, however, due to the large number of active biologically active substances, their standardization is significantly complicated, in addition, natural sources of raw materials are limited and very expensive. At the same time, practical oncology is experiencing an ever-increasing need for new drugs for the treatment and prevention of cancer, free from the disadvantages noted above, having high efficacy and the absence of side and toxic effects, while it is desirable that they are more accessible and inexpensive. In this regard, it should be noted the use of wheat bran for cancer prevention. As you know, wheat bran consists of half of dietary fiber - natural polymers: cellulose, hemicellulose, pectin, lignin, and also contain a complex of essential macro- and microelements, B vitamins. It was found that in experimental, epidemiological and clinical studies they prevent the occurrence of and the development of colon and breast cancer (Fergusop LR, Narris PJ. Protestiop agaipst sapper bu whаt bran ^Λ role оf dieter fibr apd rhutochemisls. Еur. J. Sapser Рrev. 1999, 00340

13

VoI.8.p.17-25). However, the anticancerogenic effect of wheat bran is limited only to colon and breast neoplasms and is used only orally. Wheat bran causes increased gas formation in the intestine, with prolonged use it is excreted from the body, thus causing a deficiency of calcium, magnesium, iron, zinc and other essential micronutrients, which. may lead to diarrhea. They are also contraindicated in peptic ulcer disease, in addition, the chemical composition of wheat bran is multicomponent and unstable, which complicates their standardization.

It is also known about the work of a number of researchers using peat-based biostimulants (BLT) for cancer prevention. BST is obtained from sphagnum peat as follows. The initial peat is subjected to alkaline hydrolysis, the resulting peat slurry is then oxidized with atmospheric oxygen at elevated temperature and pressure, the products are neutralized with acid and precipitated, after which they receive BST from the modification. BST or other peat oxyhumate, belongs to the class of high molecular weight organic polymers, is a product of black or dark brown color, odorless and tasteless, non-volatile, readily soluble in alkalis and alcohols, insoluble in acids and water (Mayakova E.F. and etc., Technological process for the production of growth biostimulant at Boksitogorsk biochemical plant. Proceedings of VNIITP, 1987, issue 59, p.83-88).

The use of BST as an additive to the diets of cattle, pigs, and broiler chickens is known to increase the general nonspecific resistance, improve metabolism, growth-promoting action and increase productivity. The use of BST as a stimulator of hair growth is known (patent RU Ns 2045948).

Bespalov V.G. et al. first proposed the use of BLS as an anti-cancer agent for cancer prevention. Means for the prevention of cancer based on natural plant substances, which use a peat biostimulator - peat oxyhumate (patent RU N ° 2219935, IPC 7 A 61 K 35/10, A 61 P 35/00, 2002).

As noted above, on the basis of a number of studies it has been established that the main cause of a number of diseases, including malignant neoplasm, is a weakening of the body's immune system. In this regard, one cannot fail to note the big role that work begins to play in finding the best ways and directions for the prevention of cancer, including strengthening the body’s immune system. It has been established that a rational, dietary nutrition has a significant effect on the state of the body's immune system. Recently, various biologically active food supplements (BAA) are beginning to be widely used to optimize the diet, especially for cancer patients.

Known dietary supplement for food, including an immunobiological preparation, which contains human recombinant alpha-2-interferon and immunoglobulins at the rate of 10 ³ -10 ME per 1 g of an acceptable food product. This dietary supplement significantly increases the body's defenses, however, it contains components obtained by expensive and complex methods of genetic engineering, while the biological spectrum of such an additive is quite narrow, because it introduces only certain components of the immune system into the body.

A dietary supplement was proposed based on a biologically active substance isolated from mushrooms, containing a composition of biologically active substances in vegetable oil, characterized by the following content of components, in

100 ml of an oil solution: lipids 2000 - 4000 mg, phospholipids 800 - 1200 mg, ubiquinone QlO 0.4 - 1.2 mg, vegetable oil up to 100 ml.

This biologically active additive may contain, in addition to the mentioned components, lactose, with the following content of components in the capsule, 1 gram: lipids 30-70 mg, phospholipids 14-20 mg, ubiquinone QlO 0.014-0.02 mg, lactose up to 1 gram. In another embodiment, said biologically active additive may contain a composition of biologically active substances in an aqueous alcohol solution in the following ratio of components in 100 ml of an aqueous alcohol solution: lipids 100-200 mg, phospholipids 40-60 mg, ubiquinone QlO 0, 02-0.06 mg, enzymes with protease, including collagenase, chitinase and lipase activities 20-30 mg, phospholipase AII 20-50 mg, ribonuclease 15-25 mg, β-glucan 200-400 mg, ethanol 7000-10000 mg, water up to 100 ml (patent RU JNa 2177699, IPC 7 A 23 L 1/29, 1/30, 1/054, 2000). The use of this additive allowed to significantly improve the quality of life of sick patients, to ensure a more favorable course of the underlying disease due to improved hemodynamics, reduced doses of cardiotonics compared with the control group. All the above-described agents representing the prior art, of course, contribute to a better course of treatment, partially relieve pain tolerated by patients, extend their existence, improving its quality. However, unfortunately, none of the listed tools solves the problem of treating cancer patients in a radical way. In this regard, in parallel with existing traditional drugs and treatment methods, very much attention has recently been given to diet and proper nutrition for oncological diseases. A significant number of publications by domestic and foreign authors on the problem of nutrition appeared (V. Shevchenko. Long-lived diet, M. Centropoligraf, 2003, V. A. Solovyov. Cambridge nutrition, St. Petersburg, Heva Publishing House, 2003, O.E. Molchanov et al., Proper nutrition for oncological diseases, M.-SPb., "Dilya", 2004, L. Kruglyak, Rational nutrition for cancer, IG "Bec", St. Petersburg., 2004, K.Monastyrsky, Functional nutrition, Ageless Press, 2000, etc.) containing quite serious recommendations, using which you can significantly alleviate the suffering of these pains GOVERNMENTAL, and in some cases, completely cured.

Translated from the Greek language, “diet” means a way of life, but later on “diet” began to denote a certain method of nutrition, a therapeutic factor (Shevchenko VP Long-liver diet. Special menu for every day for various diseases, for weight loss. M. , Centropolygraph, 2003, p. 318).

The great, constantly growing attention that is paid in the modern world to issues related to rational nutrition is known. This is confirmed by the amount of funds allocated in developed countries to conduct scientific research on nutrition, as well as, as noted above, by a shaft of publications on this topic. The effect of consumed products on the state of the body, as well as the relationship of nutrition with the acquisition of various diseases, is becoming increasingly apparent. In 1982, the National Academy of Sciences (USA) published the results of studies on the topic: Diet, Nutrition and CANCER (Report of the National Academy of Sciences (USA)), on the basis of which the preferred lists of products were proposed, the consumption of which reduced the likelihood of cancer. Recommendations for changing the diet were clarified in subsequent reports on this issue in 1988 and 1989. and were included in the recommendations of the most famous, fundamental reference book on oncology (Sapseg Rripsyrles & Prastice of Opsologu 6 th Editiop, 2001, p.561-600). These recommendations are as follows: - Reduce fat intake to no more than 30% of total calorie intake, followed by lower fat intake to less than 10% of total calorie intake;

- eating fruits, vegetables and cereals (wholemeal), dietary fiber, bran; - the use of plant products containing retinoids - vitamin A, carotenoids and natural dietary anti-cancer products: green, yellow-red and yellow-orange vegetables and fruits, phytoestrogenic products, products containing organic sulfur - garlic and phenolic compounds;

- eating table salt no more than 0.5 grams per day; - moderate alcohol consumption, if possible, complete abstinence.

According to studies conducted by volunteers and animals, it has been proven that fruits, vegetables and components of cereals contain components that help the body defend itself against cancer. It is believed that the American diet includes two main sources of fats: - visible fats: fats that add to food, such as vegetable oil, preferably cold-pressure olive oil (which the authors of this invention recommend in the proposed weekly menu), butter, margarine , cream, mayonnaise and salad dressing;

- hidden fats: fats found in meat, pastries and snacks. These fats provide 34% of the calories an average American consumes. Reducing this amount to 30% of all calories consumed can reduce the risk of cancer. Considering that 1 gram of fat contains 9 calories, 30% will correspond to: 57 grams for a diet of 1700 calories, 67 g - 2000 cal., 73 g - 2200 cal., 83 g - 2500 cal.

Fundamental recommendations for proper, scientifically based nutrition in oncological diseases (Molchanov O.E., Prokhorov DG Proper nutrition for oncological diseases. Moscow - St. Petersburg, Dilya, 2004, p. 266) are as follows:

- Be sure to include raw foods in the diet;

- minimum heat treatment; - eliminate canned foods;

- be sure to include dietary fiber in the diet;

- normalization of the intestine;

- use of purified water.

As a result of extensive research, it has now been established that some products containing vitamins, minerals and biological compounds have an immunostimulating and anti-carcinogenic effect: red carrots, red peppers, green onions, sorrel, lettuce, apricots, mountain ash, and wild rose.

These products contain vitamins: C, A and E (beta carotene), for which a specific action is characteristic: anti-cancer antioxidant, suppressing carcinogenesis. The specific anticancer effect of vitamin A was detected in prostate cancer and lung cancer. The same effect of beta-carotene is for cancer of the cervix, breast, lung, prostate, pancreas and large intestine (Glavapussi E. et al. Istitut. 1995, 87 (23), b. 1767; Libermap S./Maitake kimg оf Мushrооms. Los Apgles Publishmg, 1991, pp. 16-19; Olsop KB, Ripta K.J. Vitamip A apd E: Furthеr Clues for Growth Sapser Reveptiop, Jörpal Otphe Natiopal Sapser Ipstitue, 1998, 90 (6), p. 414-415; Tomato S. et Al. 1991, 15 (6), P. 491-494).

Products containing vitamin E: vegetable oils, green leaves of vegetables, eggs, seeds (grains) of wild rose. The general anti-cancer effect is antioxidant, prevents fatty degeneration of the cell, stimulates the immune system; specifically prevents cancer of the skin, prostate and large intestine (Ogiipi I., Nasu K., Yamato mototo S., Nomuga T. On the appetitive optivitis fungus tepa lef. Agris Biol. Chet, 1988, 52, p. 1879-1880; Pastorino U. et al. Adjuvapt Treftef Stag 1 Lups Sapper with High-Vitamin A, Jufal Sopliso 1993, I, p. .

Products containing vitamin C: red pepper, zucchini, broccoli, onions, garlic, tomatoes, turnips, citrus fruits, currants, strawberries, raspberries, mountain ash, rose hips.

The general anticancer effect - antioxidant, inhibits the genetic rearrangement of the cell. Specific effect - prevents cancer of the lung, trachea, esophagus, stomach, pancreas (Blosk G. et al. Vitamin C: A New Look. Ashials Optimal Medicine, 1991, 114 (10), p.909-910). Products containing vitamin D: liver, fish roe, salmon meat, liver of mammals and birds, eggs (yolk).

General anti-cancer effect - inhibits the angiogenesis of a growing tumor.

A specific effect - together with vitamin A, suppresses the estrogenic dependence of the tumor (Lurulessu A. Ipphibitiо DNA Synthesis and Neoplastic CeIl Гоwth b Vitamin A (Retіpol), Jörpul оf thе Natiopal Sapser Iппититее, 1986.77 (1) p.1 .

Products containing epilocatechins galates (EGCG): green tea, rosehip.

General anti-cancer effect: promote apoptosis of cancer cells. A specific action - suppresses the vital activity of viruses, is an immunomodulator, antioxidant, restores the function of the heart and liver after surgical interventions (Cao Y., Cao R. Apiogepesis ipu bite dripki teg, Natury, 1999, 398 (6726), p.381; Ohsaw G. The Art of Rease and Georgy Ohsawa,

Georgy Ohsawa Masrobiotis Fopdatiop, 1991, p. 243; Vitamin E apd Colop Sapser. Sapser Eridemiologu, Viomarkers and PREVEPTIOP, 1997, 6, p. 769-774). Products containing selenium: broccoli, garlic, onions, red pepper, dill seeds, garlic feathers, orange juice, wholemeal bread, bran, fish, salmon, chickens.

General anti-cancer effect: antioxidant, stimulates cellular immunity, suppresses fatty degeneration of cells, normalizes the water balance in the body. Specific anti-cancer effect - protect the skin, mammary glands, large intestine, larynx from carcinogenic effects; protect the immune system from damage during chemotherapeutic treatment (Clark L.C. et al. Effects of Selenium Supplementation of Pharmaceuticals with Pharmaceuticals of Skiing, Medicine Pharmaceuticals, 24, 1996, 27 Medicinal -1963; Sembambia G., et al. Quérétépépététés theé Efépét Adriamusip ép and Muуludga-resistapt MCF7 Numap Breast Sapper Cellulémépéllépétéporet, 4 Sépertomégéporetom 4, 1994, 4beta, 4beta, 4beta, 4beta, 4beta, 4beta, 4beta. Apiapgiogepetis Putrips suhs flavopoids, raptulapu aptisuips (foupd foods with ruple or bluetooth, parampus suhres frees, Grép, Buddy

Products containing flavonoids (quartzetine, genistein, apeginine, luteolin) are a large group of plant products containing phenolic components, which makes them similar to the hormones of the estrogen series of animals and humans: broccoli, seaweed, buckwheat, rosehips. General anti-cancer effect: suppress the mutation of the p53 suppressor. Specific effect - inhibit the development of breast, prostate, and ovarian cancers .There Sapser Reveptiop Diet, St. Martin's Griffip, New York, 1994; Redappa P. et al. Thе RoIe оf Vitamip E apd Selenium op Аdkhidopis Асid Охепепепепепефепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепепеле 1989, 570, p. 136-145).

Berries and fruits recommended for lunch have anticancer, antiviral and anti-inflammatory effects; specific action - protect the cardiovascular and nervous systems (Vatkip et al. Modulopof Metastasis (Lewis Lupg Apoptoma) bpopelpit Stupt, 2, 1988, Apopt, 2, 2, 1988; J. NATURAL Compounds in Cancer Teraru, 2001; Yan YS Effective оf Chipeсe tea exprаst on thе fuсtiop оf mісе берипg tumоr apd thеir aptumumоtivitu, Chung Hua Yu Fang I Нсуеh Тса Сhih, 1992, 26 (1), p.5-7).

Shiitake mushrooms and maitaki mushrooms have an immunostimulating effect (Kioka N. et al. Quercetip, and Bioflavoid, Iphibits the Iprease Оf Нumap Multidrig Residepse Gene (MDRl) Expreessiеcepеsе 30еsеpеsе 30 Еeсеpеsе 30 Еeсеpеser 3. ; LaRossa L.M. et al. Growth - Ipphibitu effest of Quercitypf aprepseff of Toure 11 Estroep VIPsit Sites Iprimuum Numap Tipsiul 10, Jumo 10, Jumo 10, Jumo 10, Joumou 10, Joumou 10, Minerals are contained in the following products (Balsh J.F., Balsh P. A.

Prescrtiop for Nut Nutiop, 1999, ρ.22-29):

BOR - found in apples, carrots, grapes, leafy vegetables, seeds, grains, etc .;

CALCIUM - in milk, salmon fish, leafy vegetables, broccoli, zucchini, gourds, etc .;

CHROME - in brown rice, cheese, meat, whole grains, eggs, mushrooms, etc .;

COPPER - in broccoli, garlic, mushrooms, oats, seeds, citrus fruits, etc .;

GERMANY - in garlic, mushrooms, shitaki, onions, etc .; IODINE - in marine products, in all types of marine fish, garlic, legumes, mushrooms, etc .;

IRON - in eggs, meat, liver, green leafy vegetables, rice, legumes, etc .;

MAGNESIUM - in fish, meat, vegetables and ... etc .; MOLYBDENUM - in legumes, leafy vegetables;

PHOSPHORUS - in eggs, fish, garlic, pumpkin seeds, sunflower seeds;

POTASSIUM - in dairy products, meat, vegetables;

SELENIUM - broccoli, brown rice, chickens (not from an incubator), garlic, garlic feathers, brown seaweed, onions, salmon fish, tuna, sprouted wheat, alfalfa, big burdock root, capsicum, dill seeds, blueberry, parsley , raspberry leaves, yarrow, orange juice, barley, wholemeal bread; 6 000340

21

SODIUM - in drinking water, meat, fish, vegetables; VANADIUM - in dill, fish, olives, radish, vegetable oil; ZINC - in eggs, fish, pumpkin seeds, sunflower seeds; seafood, mushrooms. In addition to choosing the optimal set of products to ensure a balanced diet, a new approach to the problem of increasing the life expectancy of people should take into account the achievements of the cytochronous concept of aging of plant and animal organisms (Balyura V.I., Balyura A.V. 1966, N ° 2, p. 13; Baluura VI, Baluura A.V. Life is PoEd. Whу? An orgiipal soport of ageipgpf plapt apd apimal orgapisms, Bulletin of Medicine, 1996, N ° 4, p.13).

According to this concept, the animal organism has a previously unknown organ - the main stem cell (an analogue of the apical cell in plants), which coordinates growth and differentiation processes, is capable of counting past and upcoming cell divisions, the genetic program of which encodes an individual development program (cell division program, cytochronous potential). This program is laid during fertilization and the exhaustion of this program leads to the death of the body.

The duration of one cell division is considered to be an elementary unit of biological time - or a cytochron. The sum of all cytochrons from the first division - zygotes to the last cell division - is the cytochronous potential of the organism's viability. It is very important that the genetic program of individual development determines, apparently, not only the number of past and upcoming cell divisions, but also the rate of differentiation of cells of various organs and tissues, and therefore their functional state.

Under the influence of the external environment in animals (like plants), a reduction in the genetic program of the number of cell divisions or an increase in their duration can occur. It should be noted that when exposed to adverse factors, cellular nutrition deteriorates, leading to an increase in the life span of the animal. For example, a low-calorie diet extended rats life by 30-40% (average life expectancy increased from 680 to 971 days, and the maximum from 898 to 1336 days) (Streler B. Time, cells and aging. M., Mir, 1964, p. 251).

According to calculations, when the temperature decreases by only one degree, the aging rate decreases by 2-3 times (Frolkis V.V. Aging and biological capabilities of the body. M., Nauka, 1975, p.272; Frolkis V.V. Experimental ways to prolong life . L., Science, 1988, p. 247). An increase in the duration of cell divisions occurring in hibernating animals leads to an increase in life expectancy by 10-15 times compared with similar animals that do not hibernate (Streler B. Time, cells and aging. M., Mir, 1964, p. 251).

On the other hand, accelerated metabolism and the associated reduction in the duration of cell divisions shorten the life of animals. For example, small animals with an accelerated metabolism pass their life path faster than large ones. The reason is that a small animal has a relatively large surface area per unit mass of body. Therefore, these animals lose heat much faster than large ones.

Interestingly, the introduction of a thyroid hormone - thyroxin, which stimulates metabolism, shortens the life of animals (Streler B. Time, cells and aging. M., Mir, 1964, p. 251; Frolkis VV Experimental ways to prolong life. L ., Science, 1988, p. 247).

There are data from various studies that if people could change the metabolic rate, the aging processes would be pushed back: a decrease in body temperature by 1 degree will extend a person’s life by 30 years.

There is some evidence to suggest that the thymus is the most likely localization of the main stem cell, although, of course, there is no conclusive evidence.

During ontogenesis, the main stem cell performs a certain number of “equal” and “constant” divisions. With equal divisions, daughter cells receive the same residual portion of the original cell division program that the mother stem cell had at the time of this division; if unequal - shortened division programs. Daughter cells from equal divisions of the main stem cell become 1st order stem cells. In subsequent equal divisions of a stem cell of the 1st order stem cells of the 2nd order arise. Thus, stem cells of organs, tissues, segments, etc. arise (stem cells of 1, 2,3 ... order).

A characteristic feature of stem cells is their ability to repeatedly replicate and differentiate into different types of secondary cells. The functioning of the main stem cell in animals is probably mandatory during growth and maturation. In the event of the death of the main stem cell, its functions are taken over by the 1st order stem cells, in the case of the death of the 1st order stem cell, the 2nd order stem cells, etc. After exhausting the cytochronous potentials of stem cells, old age comes and death occurs.

The cells with the help of which information is transferred from the main stem cell to stem cells of the 1,2,3 ... order and further to the effector cells of various organs and tissues are, apparently, T-lymphocytes. In this regard, the data of A.G. Babayeva are interesting (Babaeva A.G. Regeneration and immunogenesis system. M., Medicine, 1985, p. 255.), From which it follows that the first partial hepatectomy increases the ability of lymphocytes to transmit repair information during reoperation. This fact resembles the phenomenon of immunological memory. In these cases, repeated regeneration proceeds much faster than the primary one (Babaeva A.G. Regeneration and immunogenesis system. M., Medicine, 1985, p. 255; Babaeva A.G., Zotikov E.A. Immunology of the processes of adaptive growth of proliferation and their disorders. M., Nauka, 1987, p.207).

It can be assumed that with the help of T-lymphocytes, direct and feedback between the main stem cell, stem cells

1,2,3 ... order and effector cells. In other words, the regulation of selective activation of genes is carried out using cooperative stem cell activity.

Thus, on the basis of the cytochronous concept of aging of animal organisms, a theoretical opportunity appeared not only to extend the life of cancer patients, but also to stop the course of the tumor process. For this, it is necessary to maximize the duration of cell divisions.

The authors of the claimed invention for several decades, dealt with the rational nutrition of cancer patients and created the optimal set of food products with an immunostimulating effect and at the same time significantly reducing the aggressiveness of the cancer process and restore immunity.

The closest to the claimed invention in essence and the achieved result in the process of use is the diet recommended by the Director of the Institute of Solid State Physics of Bochum University, Professor X. Zabel. He considers rational nutrition as the basis for the treatment of cancer patients and believes that using a certain set of products, you can achieve the necessary changes in metabolic processes in the cells. Such a set of products should include skim milk, lactic acid products, flour and whole grains, raw (vegetable) food, boiled vegetables, vegetable oils with a high content of unsaturated, fatty acids (JI. Kruglyak. A rational diet for cancer, IG "Bec" , St. Petersburg, 2004, p. 67). However, the proposed diet is quite general, more of a recommendatory nature, while the claimed invention provides a specific list of products that suppress the carcinogenic properties of the tumor.

The task underlying the present invention is to use a specific set of products for the treatment of cancer. The technical result achieved in the process of using the claimed invention consists in the treatment of almost all varieties of malignant neoplasms without exception, without the use of radiation, chemotherapy, and in the process of nutrition with a specially selected set of products.

The task underlying the present invention with the achievement of the aforementioned technical result is solved by the fact that the well-known set of products, including flour, whole grains, vegetable oil, boiled vegetables, additionally contains: dogrose flour, buckwheat, bran, green tea, bread from wholemeal flour, beans, lentils, fresh and dried shitaki or mantaka mushrooms, fresh salmon, non-incubator chickens, onions, garlic, carrots, tomatoes, white cabbage, Brussels sprouts, cauliflower, broccoli, red beets, pepper not bitter (red, yellow, green), celery, dill, parsley, wormwood, blueberries, grapes, pineapple, dad, lemon, orange, olive oil in the following ratio of components in g: rosehip flour 205 - 210, buckwheat groats 340 - 350, bran 65 - 70, green tea 32 - 35, wholemeal bread 980 - 1000, beans 190 - 200, lentils 190 - 200, shiitake or mantaka mushrooms fresh 290 - 300 and dried 145 - 150, salmon fresh 290 - 300, non-hatchery chickens 140 -150, onions 190-200, garlic 90 - 95, carrots 1450 - 1500, tomatoes 1450 - 1500 , white cabbage 450-500, Brussels sprouts 450-500, cauliflower 450-500, broccoli 290-300, red beets 470-500, pepper not bitter (red, yellow, green) 340-350, celery 18-20, crop 18-20, parsley 18-20, wormwood 18-20, blueberries 380-400, grapes 380-400, pineapple 2600-2700, dad 2400-2450, lemon 240-250, orange 260-270, olive oil 340-350 .

The proposed list of products provides the patient with the necessary amount of vitamins C, A, D, E, K and biologically active flavonoids - quartzetine, luteolin, apiginin, bromelain, which have an anticarcinogenic effect and prevent the development of cancer at all 7 stages of its growth (Jonh Boik, Natural Comprods IP Sapser therapy, 2001).

The restoration of immunity is carried out through products containing selenium and vitamin E. May hips contains: carotene (vitamin A precursor) 9, 75 mg%, pectin substances 14.1%, citric acid 1.58%, total sugars 23.93%, inverted Sugars 18.56%, sucrose 5.99%, pentosans 8.92%, vitamin P, including quartzetine and isocvercitin 4%, anthocyanins 45mg%. Buckwheat groats: vitamin P, including quartzetin8%.

By the number of vitamins: C, A, D, E, K, quartzetine, both rosehip and buckwheat products contain more than half of the recommended by the inventors to block the cancer process at all stages of its development and restore immunity.

The concentration of biologically active compounds and vitamins in dogrose and buckwheat is more than three times higher than in the prototype. The authors found that to suppress the cancer process, it is necessary to limit the intake of arachidonic acid and fatty acids into the developing tumor, and to suppress the angiogenesis of the growing tumor and apaptosis of growing cancer cells, quartzetin is needed, which is most found in rosehips and buckwheat. This is the main essence of the proposed invention.

The authors also offered a menu for the week. The repetition of the seven-day menu for 3-6 months is due to the cyclical life of the cancerous tumor.

It should be noted that the claimed set of products is the necessary and minimum list of products that a cancer patient must consume every week during treatment. From many years of treatment experience it follows that the long-term use of a limited range of products is very tiring for the patient and not all patients cope with this, even if they mobilize all their willpower and desire to overcome a serious illness.

Therefore, to facilitate the assimilation of the required products listed in the weekly menu, the authors offer additional, optional products that will only facilitate the systematic long-term adoption of a limited, uniform list of products for the patient.

The proposed weekly menu is as follows.

Breakfast (Monday, Wednesday, Saturday). In 30 minutes Before breakfast, porridge is prepared from one tablespoon of rosehip flour. To do this, 100 grams of rose hips need to grind in a coffee grinder to a fine flour, sift. Grind the leftovers in a mortar and mix with the main flour. Take one tablespoon of the resulting mixture, dilute with cold boiled water to the consistency of liquid porridge. Add one dessert spoon of flower honey to the obtained porridge. Eat slowly.

Freshly cooked buckwheat porridge, with bran and olive oil. Green tea with raisins (instead of sugar), 50 grams of wholemeal bread.

Breakfast (Tuesday, Thursday). Oatmeal made from cereals or cereal with bran and olive oil. Green tea with raisins (instead of sugar), 50 grams of wholemeal bread.

Breakfast (Friday, Sunday). Brown rice porridge with bran and olive oil. Green tea with raisins (instead of sugar), 50 grams of wholemeal bread. Method of making porridge: pour 0.5 cups of cereal with two cups of water, cook for 20-25 minutes. At 13-17 minutes add one tablespoon wheat bran. After cooking, add two tablespoons of cold-pressed olive oil.

Lunch (Monday, Thursday). Fresh blueberries. Lunch (Tuesday, Friday). Grapes with pits. Lunch (Wednesday, Saturday, Sunday). A pineapple.

Lunch (Monday, Thursday). In 30 minutes Before lunch, porridge made from rosehip flour with floral honey, as for breakfast.

Soup: a cup of beans, chop 1 head of onion, 2 stalks of celery, 3 carrots, add 2 tablespoons of olive oil and 4 glasses of water. Cook for 30 minutes.

The second dish: salmon fish. Method of preparation: 100-150 grams of fish, 2 stalks of asparagus, 2 small tomatoes, 4-5 shitaki mushrooms, 5 grapes without grains, 3 tablespoons of vegetable oil, a teaspoon of lemon juice, 1 garlic clove, dill, fresh green pepper. Cook in a deep skillet over low heat for 15 minutes.

Lunch (Tuesday, Friday). Soup: 0.7 cups of lentils, 4 cups of water, cut 1 head of onion, 2 carrots, 2 stalks of celery, add 2 stalks of parsley, 2 stalks of dill, thyme, 1 sprig of wormwood. Cook for 30 minutes.

Second course: chickens (preferably not incubator) with ginger and onions. Method of preparation: 200 grams of chicken without skin, cut 2 large onions and 1 tomato, 2 tablespoons of vegetable oil, a tablespoon of white wine, a teaspoon of fresh ginger, 2 tablespoons of orange juice, a teaspoon of grated orange peel, a cup of grapes without grains. Pour the chopped chicken into cold water in a pan, cook for 3 minutes. Then put onion, vegetable oil and fry until light brown. Then add a mixture of ginger, white wine, orange juice, grated orange peel.

Cook 3-5 minutes. Put everything on a dish and decorate with grapes.

Lunch (Saturday, Sunday). Soup: chop 1 head of onion, 3-5 stalks of asparagus, 3-5 cloves of garlic, 2-3 slices of burdock, 100 grams of shitaki mushrooms, carrots, celery, 1 beet, 100 grams of cabbage, cook for 30 minutes.

The second dish: any vegetarian dishes. Bread 150-200 grams from wholemeal flour. On the third, any natural juices, freshly prepared, sugar free 200-250 grams.

Dinner (daily). Any vegetarian dish, almonds, Brazil nuts, peanuts. Green tea with raisins. Salads from any raw vegetables should be prepared for the second dishes on all days of the week, adding 4-5 branches of dill with seeds, chopped onions (feathers and onions), garlic, 3-5 branches of parsley, 2-3 branches of mint, a little seaweed, a tablespoon of olive oil.

Stewed vegetables for vegetarian days: medium-sized beets, 2 carrots, 100 grams of broccoli, 100 grams of Brussels sprouts, 100 grams of cauliflower, 1 capsicum, 1 tablespoon of olive oil. Cut and stew vegetables for 30 minutes. The ratio of the number of vegetables consumed to the number of fish or chicken should be 3: 1.

The table shows the products, their weight and calories needed by the cancer patient for a week.

Product name Weight (in grams) Number of calories rosehip flour 205.0 - 210.0 1280 buckwheat groats 340.0 - 350.0 2478 bran 65.0 - 70.0 180 green tea 32.0 - 35.0 bread made from flour coarse grinding 980.0 - 1000.0 2478 beans 190.0 - 200.0 750 lentils 190.0 - 200.0 750 fresh shiitake or maitaki mushrooms 290.0 - 300.0 126 dried 145.0 - 150.0 fish fresh salmon 290.0 - 300.0 609 chickens (not hatchery) 140.0 - 150.0 166.5 medium onions 190.0 - 200.0 280 garlic 90.0 - 95.0 120 carrots 1450.0 - 1,500.0 600 tomatoes 450.0 - 1,500.0 345 white cabbage 450.0 - 500.0 155 brussels sprouts 450.0 - 500.0 235 cauliflower 450.0 - 500.0 235 broccoli 290.0 - 300.0 175 red beets 470.0 - 500.0 165 peppers not bitter (red, yellow, green) 340.0 - 350.0 296 celery 18.0 - 20.0 dill 18.0 - 20.0 parsley 18.0 - 20.0 wormwood 18.0 - 20.0 blueberries 380.0 - 400.0 228 grapes 380.0 - 400.0 296 pineapple 2600.0 - 2700.0 141 dad 2400.0 - 2450.0 1053 lemon 240.0 - 250 ^" , 0 215 oranges 260.0 - 270.0 210 olive oil 340.0 - 350.0 3150

TOTAL: 16944.5

Examples of specific applications of the proposed set of products. Example 1. Patient 34 years. Diagnosis: Cancer of the left breast gland Stage III TZN1M0, the state after radical mastectomy and radiotherapy in 1972. The patient underwent chemotherapy according to the standard CMF regimen (cyclophosphamide + metectrate + 5ftopyracil) on the background of a 100% cereal diet, which the patient maintained for three years. In the future, the complete exclusion of sugar, salt, animal proteins. Salts are not more than 0.5 grams per day. Last survey in 1998: no data for relapse and metastasis.

Example 2. Patient 38 years. Diagnosis: Cancer of the right breast IV Art. T 2 NlMl. Cancer metastases to the lung. The patient was transferred to a 100% cereal diet, twice a day in the morning before breakfast and in the afternoon before meals - liquid porridge from brown (May) rosehip flour. The patient underwent three courses of chemotherapy according to the standard ACMF regimen (adriablastin + cyclophosphamide + methotrexate + 5ftopyracil). Three months later, during a follow-up examination, lung metastases were not detected.

Example 3. Patient 37 years. Diagnosis: Cancer of the right mammary gland 116 tbsp. T2 Nl MO. Radical mastectomy, postoperative radiation therapy and 6 courses of chemotherapy according to the CMF scheme. After 3 years, cancer metastases to the liver. The liver is three transverse fingers below the edge of the costal arch. The patient was transferred to a 100% cereal diet, twice a day - porridge from dogrose flour. On day 25, the liver contracted to normal size. Later, the patient developed cirrhosis of the liver, as a result of which the patient died. At autopsy, liver metastases were not detected.

Example 4. Patient 63 years. Diagnosis: Cancer of the right breast T2 Nl MO. Comprehensive treatment. After 9 years, metastases in the 12 thoracic vertebra with compression fracture and compression of the spinal cord, flaccid paralysis of both lower extremities. The patient was assigned a 100% cereal diet and a forced position on his back on a wooden shield. After 6 weeks, the patient stood on crutches and went. The last visit to the sick doctor was a year later, the patient on her own on public transport, leaning on a stick, came to the doctor for an appointment.

Example 5. Patient 15 years. Diagnosis: Lymphogranulomatosis with lesions of the lymph nodes above and below the diaphragm. 6 chemotherapy courses at the VSC was ineffective - there was an increase in lymph nodes. The patient was transferred to a 100% cereal diet, against the background of which chemotherapy was carried out according to the CORR-b scheme. At 100% cereal diet, the patient was 24 weeks. A year later, the patient got married, gave birth to two daughters. The last examination after 15 years of data for the recurrence of lymphogranulomatosis was not.

Example 6. The patient is 19 years old. Diagnosis: Lymphogranulomatosis, stage IV, damage to the lymph nodes above and below the diaphragm, liver damage. Ascites. Against the background of a 100% cereal diet, the patient was given 6 courses of COPP. After the first 2 courses of COPP against the background of a 100% cereal diet, ascites was not determined, the lymph nodes of the neck decreased. The patient graduated from high school, the Institute of Communications. He went to work in one of the banks. Errors in the diet began. As soon as the patient switched to the general table, relapse occurred. Treatment all the traditional methods of chemotherapy at the Hematology Center AM Russia was not effective.

Example 7. Patient 50 years. Diagnosis: Lymphosarcoma with the defeat of feather plaques stage 111 tbsp. The symptom of the disease was expressed in frequent, up to 24 times a day, loose stool. After transferring the patient to a 100% cereal diet, on day 5, the stool became 3 times a day. The patient noted that when switching to a common table, the chair immediately became more frequent.

Example 8. The patient is 40 years old. Diagnosis: Lymphosarcoma of the stomach and mesenteric lymph nodes soldered together in a single conglomerate with a diameter of up to 20 cm stage IV art. The patient was transferred to a 100% cereal diet and 6 courses of ACOP chemotherapy were performed (Adriamycin + Cyclophosphamide + Vincristine + Procarbazine). The tumor is no longer being determined. The patient strictly adhered to the cereal diet for 2.5 years. The last examination at the oncological institute did not reveal a relapse of lymphosarcoma. Example 9. Patient 72 years. Diagnosis: Ovarian cancer T2N1M1, peritoneal metastases, ascites. The patient underwent 6 courses of ACOP (Adriamycin + Cyclophosphamide + Vincristine + Procarbazine) without effect. When transferring the patient to a 100% cereal diet, three more ACOP courses were performed with a positive effect - ascites decreased, the patient began to do housework. The patient lived for 2 years. Example 10. Patient 58 years old. Diagnosis: Prostate cancer T2N1M1 with metastases in the pelvic bone, with germination in the urethra. The patient has severe pain during urination. When transferring the patient to a 100% cereal diet and rosehip porridge, the pain syndrome stopped after 7 days. The patient was given 4 courses of ACOP. The patient lived without pain for 3 years. Example 11. Patient 55 years old. Diagnosis: Lymphogranulomatosis with damage to all groups of peripheral lymph nodes stage 1 V st. The last three months the patient in the evening, the temperature rose to 39.5-40.5 degrees. When transferring the patient to a 100% cereal diet and rosehip porridge, the temperature on the 5th day returned to normal. After three weeks, the peripheral lymph nodes decreased significantly. The patient stayed on the proposed diet for 3 months. Considering himself healthy, despite the doctor’s warnings, he switched to the general table. Rapid relapse occurred on the third day of the general table, the patient died after 3 weeks.

Example 12. Patient 32 years. Cancer of the right breast T2N1M0. Operation radical mastectomy, chemotherapy 6 courses of CMF (cyclophosphamide + methotrexate + 5 fluorouracil) and radiation therapy. Two years after the last course of chemotherapy, the patient developed jaundice; liver scans revealed liver metastases. The patient was transferred to a 100% cereal diet and started treatment with microclysters of horseradish infusion every other day for a month, with a control scan of the liver metastases were not detected. Six months later, stress - a divorce from her husband, relapse of liver metastases.

Example 13. The patient is 77 years old. Skin cancer of the right lower leg T2N0M0, the operation is a wide excision of the tumor. Two years later, cancer metastases in the right inguinal and left axillary regions. A cytological examination revealed metastases of a malignant neuroepithelial tumor (Merkell cellulitis). Sick US citizen. Lives in New York. After the first course of chemotherapy (Adriamycin - Taxol) metastases remained unchanged. The patient was transferred to a cereal diet. Three weeks after the appointment of the diet, a second course of the same chemotherapy was carried out. Two months after the examination of the patient, when the above metastases were revealed and 5 weeks after chemotherapy, when examining the patient, metastases were not detected in the right inguinal region or in the left axillary.

The proposed set for weekly dietary nutrition, unlike many therapeutic drugs used to treat oncology and which are highly specialized, provides suppression of any types of oncology at all stages of tumor development due to restoration of the normal functioning of the complex in which the P-53 gene is located. The use of products containing them instead of vitamins directly also allows you to gently affect the body, restore impaired immunity without side effects, expand the range of pharmacological effects, and increase the effectiveness of chemotherapy.

The proposed set of products, in addition to the identified effective therapeutic effects, can be used for prevention and prevention oncological diseases. Organized diet food, based on the proposed set of products, can be recommended for centenarians.

Claims

Claim

A set of products for a weekly diet for the nutrition of cancer patients, including flour, whole grains, vegetable oil, boiled vegetables, characterized in that the dog rose flour is used as flour, buckwheat is used as cereal, while it additionally contains: bran, green tea, wholemeal bread, beans, lentils, shitaki or mantaka mushrooms, fresh and dried, fresh salmon, non-incubator chickens, onions, garlic, carrots, celery, dill, parsley, wormwood, blueberries, grapes, pineapple, papa, lemon, orange, ol wok oil, white cabbage, as boiled vegetables are used: Brussels sprouts, cauliflower, broccoli, red beets, non-bitter pepper (red, yellow, green), with the following ratio of components in grams: rosehip flour 205 - 210, buckwheat 340 - 350, bran 65 - 70, green tea 32 - 35, wholemeal bread 980 - 1000, beans 190 - 200, lentils 190 - 200, fresh shitaki or mantaka mushrooms 290 - 300 and dried 145 - 150, fresh salmon 290 - 300, non-hatchery chickens 140 -150, onions 190-200, garlic 90 - 95, carrots 1450 - 1500, tomatoes 1450 - 1500, white cabbage 450-500, Brussels sprouts 450-500, cauliflower 450-500, broccoli 290-300, red beets 470-500, pepper not bitter (red, yellow, green) 340-350, celery 18-20, dill 18- 20, parsley 18-20, wormwood 18-20, blueberries 380-400, grapes 380-400, pineapple 2600-2700, dad 2400-2450, lemon 240-250, orange 260-270, olive oil 340-350.