WO2007138233A3 - Use of zatosetron for the treatment of rosacea, and pharmaceutical compositions - Google Patents

Use of zatosetron for the treatment of rosacea, and pharmaceutical compositions Download PDF

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Publication number
WO2007138233A3
WO2007138233A3 PCT/FR2007/051361 FR2007051361W WO2007138233A3 WO 2007138233 A3 WO2007138233 A3 WO 2007138233A3 FR 2007051361 W FR2007051361 W FR 2007051361W WO 2007138233 A3 WO2007138233 A3 WO 2007138233A3
Authority
WO
WIPO (PCT)
Prior art keywords
zatosetron
rosacea
treatment
pharmaceutical compositions
composition
Prior art date
Application number
PCT/FR2007/051361
Other languages
French (fr)
Other versions
WO2007138233A2 (en
Inventor
Jean-Dominique Pierret
Fabrizio Dolfi
Christian Loesche
Nadege Tremel
Original Assignee
Galderma Res & Dev
Jean-Dominique Pierret
Fabrizio Dolfi
Christian Loesche
Nadege Tremel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev, Jean-Dominique Pierret, Fabrizio Dolfi, Christian Loesche, Nadege Tremel filed Critical Galderma Res & Dev
Publication of WO2007138233A2 publication Critical patent/WO2007138233A2/en
Publication of WO2007138233A3 publication Critical patent/WO2007138233A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to the use of zatosetron or the salts thereof as an active substance in a pharmaceutical composition, especially a dermatological composition. The composition is preferably topically applied and is used for the treatment and/or prevention of rosacea.
PCT/FR2007/051361 2006-05-31 2007-05-31 Use of zatosetron for the treatment of rosacea, and pharmaceutical compositions WO2007138233A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0651984 2006-05-31
FR0651984A FR2901703B1 (en) 2006-05-31 2006-05-31 USE OF ZATOSETRON FOR THE TREATMENT OF ROSACEA, AND PHARMACEUTICAL COMPOSITIONS

Publications (2)

Publication Number Publication Date
WO2007138233A2 WO2007138233A2 (en) 2007-12-06
WO2007138233A3 true WO2007138233A3 (en) 2008-01-24

Family

ID=37663114

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2007/051361 WO2007138233A2 (en) 2006-05-31 2007-05-31 Use of zatosetron for the treatment of rosacea, and pharmaceutical compositions

Country Status (2)

Country Link
FR (1) FR2901703B1 (en)
WO (1) WO2007138233A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2942138A1 (en) * 2009-02-16 2010-08-20 Galderma Res & Dev ASSOCIATION OF COMPOUNDS FOR THE TREATMENT OR PREVENTION OF DERMATOLOGICAL DISEASES
KR20120104512A (en) 2009-07-14 2012-09-21 알바니 몰레큘라 리써치, 인크. 5-ht3 receptor modulators, methods of making, and use thereof
FR2960152A1 (en) * 2010-01-27 2011-11-25 Galderma Res & Dev Means limiting the expression of the gene encoding histamine receptor H2 and/or an antagonist of histamine receptor H2 for the treatment of e.g. rosacea, erythematotelangiectatic rosacea and papulopustular rosacea (subtype II)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0307172A2 (en) * 1987-09-08 1989-03-15 Eli Lilly And Company Improvements in or relating to specific 5-HT3 antagonists
WO2005058312A1 (en) * 2003-12-10 2005-06-30 Galderma Research & Development, S.N.C. Use of ondansetron for the treatment of inflammation, and pharmaceutical compositions thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0307172A2 (en) * 1987-09-08 1989-03-15 Eli Lilly And Company Improvements in or relating to specific 5-HT3 antagonists
WO2005058312A1 (en) * 2003-12-10 2005-06-30 Galderma Research & Development, S.N.C. Use of ondansetron for the treatment of inflammation, and pharmaceutical compositions thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JANSEN T: "Influence of the 5-HT3 receptor antagonist granisetron on erythema and flushing tendency in rosacea patients", KOSMETISCHE MEDIZIN, GROSSE VERLAG GMBH, BERLIN, DE, vol. 26, no. 1, 2005, pages 22 - 24, XP009075700, ISSN: 1430-4031 *
PROUS J ET AL: "Zatosetron maleate: Anxiolytic 5-HT-3-receptor antagonist", DRUGS OF THE FUTURE, vol. 19, no. 9, 1994, pages 850 - 853, XP008073961, ISSN: 0377-8282 *

Also Published As

Publication number Publication date
FR2901703B1 (en) 2012-12-07
FR2901703A1 (en) 2007-12-07
WO2007138233A2 (en) 2007-12-06

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