WO2007129269A3 - Novel intermediates, process for their preparation and process for the preparation of coq10 employing the said novel intermediates - Google Patents

Novel intermediates, process for their preparation and process for the preparation of coq10 employing the said novel intermediates Download PDF

Info

Publication number
WO2007129269A3
WO2007129269A3 PCT/IB2007/051676 IB2007051676W WO2007129269A3 WO 2007129269 A3 WO2007129269 A3 WO 2007129269A3 IB 2007051676 W IB2007051676 W IB 2007051676W WO 2007129269 A3 WO2007129269 A3 WO 2007129269A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
novel intermediates
coq10
employing
coqlo
Prior art date
Application number
PCT/IB2007/051676
Other languages
French (fr)
Other versions
WO2007129269A2 (en
Inventor
Mita Roy
Abhay Atmaram Upare
Amit Anant Chavan
Dabeer Rauf Karnalkar
Original Assignee
Nicholas Piramal India Ltd
Mita Roy
Abhay Atmaram Upare
Amit Anant Chavan
Dabeer Rauf Karnalkar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicholas Piramal India Ltd, Mita Roy, Abhay Atmaram Upare, Amit Anant Chavan, Dabeer Rauf Karnalkar filed Critical Nicholas Piramal India Ltd
Publication of WO2007129269A2 publication Critical patent/WO2007129269A2/en
Publication of WO2007129269A3 publication Critical patent/WO2007129269A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to an improved process for the preparation of Coenzyme Q. Coenzyme QlO or CoQlO has the chemical name 2- [(all -trans)- 3, 7,l l,15,19,23,27,31,35,39-decamethyl-2, 6, 10, 14, 18, 22, 26, 30, 34, 38 - tetracontadecaenyl]-5-6-dimethoxy -3- methyl -1,4-benzoquinone and has the formula 1. The invention also provides new intermediates useful for the preparation of CoQlO and processes for their preparation.
PCT/IB2007/051676 2006-05-05 2007-05-04 Novel intermediates, process for their preparation and process for the preparation of coq10 employing the said novel intermediates WO2007129269A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN706/MUM/2006 2006-05-05
IN706MU2006 2006-05-05

Publications (2)

Publication Number Publication Date
WO2007129269A2 WO2007129269A2 (en) 2007-11-15
WO2007129269A3 true WO2007129269A3 (en) 2009-04-23

Family

ID=38668160

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/051676 WO2007129269A2 (en) 2006-05-05 2007-05-04 Novel intermediates, process for their preparation and process for the preparation of coq10 employing the said novel intermediates

Country Status (1)

Country Link
WO (1) WO2007129269A2 (en)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MIN ET AL.: "The Friedel-Crafts Allylation of a Prenyl Group Stabilized by a Sulfone Moiety.", JOURNAL OF ORGANIC CHEMISTRY, vol. 68, 2003, pages 7925 - 7927 *
OLSON ET AL.: "Vitamin A Synthesis by Sulfone Alkylation-Elimination.", JOURNAL OF ORGANIC CHEMISTRY., vol. 41, no. 20, 1976, pages 3287 - 3293 *
TRUCE ET AL.: "The Copper-Catalyzed Addition of Arenesulfonyl Chlorides to Conjugated Dienes, Trienes, and Phenylacetylene.", JOURNAL OF ORGANIC CHEMISTRY., vol. 35, no. 12, 1970, pages 4217 - 4220 *

Also Published As

Publication number Publication date
WO2007129269A2 (en) 2007-11-15

Similar Documents

Publication Publication Date Title
WO2007004092A3 (en) Novel intermediates, process for their preparation and process for the preparation of coq10 employing the said novel intermediates
DE602006010132D1 (en) Intermediates for the preparation of trans-5-chloro-2-methyl-2,3,3a, 12b-tetrahydro-1h-dibenzE2,3: 6,7O-oxo-amino-4,5-cpyrrole
ZA200800828B (en) Processes for the preparation of 4-amino-2-(2,6-diox-opiperidin-3-yl)isoindoline-1,3-dione compounds
WO2006110783A3 (en) Process for making (s)-pregabalin
SI2044043T1 (en) 1- Y?á- (2, 4-DIMETHYLPHENYLSULFANYL) -PHENYL?åPIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT
WO2009156462A3 (en) Organic compounds
CL2013002895A1 (en) Compounds derived from 7,8-dihydro-5h-pteridin-6-one, useful as intermediates in the synthesis of compounds derived from pteridinone (divisional of application 3123-2005).
MY146405A (en) Fast-release microcapsule products
WO2007062190A3 (en) Chemical compounds
WO2006091457A3 (en) Ionic liquids derived from peracid anions
WO2006034093A3 (en) 3- (2-acylamino-1-hydroxyethyl)- morpholine derivatives and their use as bace inhibitors
ZA200904333B (en) Process for the preparation of 6,6-Dimethyl-3-azabicyclo-[3.1.0]-hexane compounds utilizing bisulfite intermediate
WO2010027150A3 (en) New preparation of hydroxychloroquine
TW200745039A (en) Isotopically substituted pantoprazole
WO2004106322A3 (en) Polymorphs of aripiprazole
WO2007095630A3 (en) New ubiquinone analogs and methods of use
WO2008153937A3 (en) Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
WO2007132354A3 (en) Process for preparing voriconazole, new polymorphic form of intermediate thereof, and uses thereof
WO2008065282A3 (en) Substituted pyrazoles, compositions containing these, method of production and use
WO2007098273A3 (en) Novel crystalline forms of armodafinil and preparation thereof
WO2007047972A3 (en) Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
WO2009062659A3 (en) Polymorphs of enantiopure erdosteine
WO2005012227A3 (en) Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine
AP2277A (en) Process for production of 1,2,2,2-tertafluoro ethyl difluoro methyl ether.
WO2007017758A3 (en) Novel cysteine protease inhibitors and their therapeutic applications

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07735768

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07735768

Country of ref document: EP

Kind code of ref document: A2