WO2007128554A8 - Lipolytic enzymes - Google Patents

Lipolytic enzymes Download PDF

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Publication number
WO2007128554A8
WO2007128554A8 PCT/EP2007/004022 EP2007004022W WO2007128554A8 WO 2007128554 A8 WO2007128554 A8 WO 2007128554A8 EP 2007004022 W EP2007004022 W EP 2007004022W WO 2007128554 A8 WO2007128554 A8 WO 2007128554A8
Authority
WO
WIPO (PCT)
Prior art keywords
lipolytic enzymes
provides isolated
provides
cholesterol
ester
Prior art date
Application number
PCT/EP2007/004022
Other languages
French (fr)
Other versions
WO2007128554A3 (en
WO2007128554A2 (en
WO2007128554A9 (en
Inventor
Tatjana M Becker
Dagmar Kratky
Gerhard M Kostner
Sanja Levak-Frank
Original Assignee
Tatjana M Becker
Dagmar Kratky
Gerhard M Kostner
Sanja Levak-Frank
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tatjana M Becker, Dagmar Kratky, Gerhard M Kostner, Sanja Levak-Frank filed Critical Tatjana M Becker
Publication of WO2007128554A2 publication Critical patent/WO2007128554A2/en
Publication of WO2007128554A9 publication Critical patent/WO2007128554A9/en
Publication of WO2007128554A3 publication Critical patent/WO2007128554A3/en
Publication of WO2007128554A8 publication Critical patent/WO2007128554A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The invention relates to the field of lipolytic enzymes, more specifically, to ester hydrolases involved in cholesterol metabolism. Therefore, the invention provides isolated nucleic acids encoding a neutral cholesterol, ester hydrolase activity, whereby the coding sequence of said gene is at least 70% homologous to SEQ ID No. 1 2 provided herein. Furthermore, the invention provides isolated proteins having the said activity encoded by the nucleic acid of the invention. In yet another aspect, the invention provides an antibody directed against the protein as mentioned hereinabove.
PCT/EP2007/004022 2006-05-05 2007-05-07 Lipolytic enzymes WO2007128554A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79765406P 2006-05-05 2006-05-05
US60/797,654 2006-05-05

Publications (4)

Publication Number Publication Date
WO2007128554A2 WO2007128554A2 (en) 2007-11-15
WO2007128554A9 WO2007128554A9 (en) 2008-02-21
WO2007128554A3 WO2007128554A3 (en) 2008-04-03
WO2007128554A8 true WO2007128554A8 (en) 2009-07-09

Family

ID=38668116

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/004022 WO2007128554A2 (en) 2006-05-05 2007-05-07 Lipolytic enzymes

Country Status (1)

Country Link
WO (1) WO2007128554A2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19941545A1 (en) * 1999-09-01 2001-03-15 Messer Griesheim Gmbh Method and device for using the cold of a cryogenic, liquefied gas
US7879544B2 (en) * 2002-07-29 2011-02-01 Hmgene Inc. Methods of identifying adipocyte specific genes, the genes identified, and their uses
JP2006141233A (en) * 2004-11-17 2006-06-08 Dainippon Sumitomo Pharma Co Ltd Secretory protein relating to enlargement of fat cell

Also Published As

Publication number Publication date
WO2007128554A3 (en) 2008-04-03
WO2007128554A2 (en) 2007-11-15
WO2007128554A9 (en) 2008-02-21

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