WO2007118430A1

WO2007118430A1 - A functional composite material with good curative effect and preparation, uses thereof

Info

Publication number: WO2007118430A1
Application number: PCT/CN2007/001244
Authority: WO
Inventors: Mengjun Yang; Zhilong Xu; Ping Li; Zhe Yang
Original assignee: Mengjun Yang; Zhilong Xu; Ping Li; Zhe Yang
Priority date: 2006-04-17
Filing date: 2007-04-16
Publication date: 2007-10-25
Also published as: CN101057980B; CN101057980A

Abstract

A functional composite material with good curative effect can be made of 66-96wt% tourmaline superfines and/or crystal infrared material superfines, 0.01-30wt% media reinforcing material and 1-5wt% embedding agent, and one or more soft solid substrate material or adhesive may be further incorporated into the powder of the composite to obtain a composite in form of soft or hard solid. The composite material can be produced into various passive medical apparatuses to effectively cure various non-infectious and non-nutritional diseases by treating at sensitive spots of the body surface instead of acupuncture, medication and active mechanotherapy, so it can be applied for health care, therapy and healing of people.

Description

High-efficiency functional composite material, preparation method and use thereof

The invention belongs to the field of powder products and relates to a medical functional composite material with high curative effect. More specifically, the invention relates to a composite material comprising a tourmaline and/or crystalline infrared material. The invention also relates to methods of making and using the materials.

Background technique

World medicine has entered the second health revolution from the first health revolution. Existing medical technology has definitive treatments for infectious diseases and nutritional diseases. However, many chronic diseases other than infectious diseases and nutritional diseases lack ideal therapeutic techniques.

Chronic diseases currently account for the largest number of patients worldwide (more than 70% of adults suffer from varying degrees of chronic disease), with the highest proportion of deaths (World Health Organization warns that by 2015, the global number of chronically ill deaths will reach 4 100 million people), the highest medical expenses (accounting for nearly 60% of the total global medical expenses). Moreover, chronic diseases often require long-term medical treatment or even lifelong treatment, and the harm of drugs and side effects is also very large. For example, the number of people who die from adverse drug reactions in China every year reaches Nearly 200,000 people, each year due to adverse drug reactions, up to 30% of inpatients (People's Health Prevention and Treatment, People's Health Publishing House, 2002 edition), drug injury, drug abuse, drug dependence has become a global Outstanding issues. Due to the high incidence and refractory of chronic diseases, the toxic side effects of drugs are becoming more and more prominent. The ideal technology for non-drug and non-surgical treatment of chronic diseases is very scarce.

Tourmaline materials have been successfully used in the radio industry and ceramics, clothing, tobacco and other industries. The Japanese scientific community uses tourmaline for environmental protection, household chemicals, plastics, building decoration, automotive, defense, coatings, soil improvement, water treatment, Purify the air, shield electromagnetic radiation, cosmetics, health products, health clothing and other aspects. In the field of health, the existing technical inventions of tourmaline composites are limited to general auxiliary health care functions, and the health care functions are relatively simple, and the health care effects are not satisfactory. It has not been invented by the specific agitation of biological waves on the surface of sensitive surfaces (acupoints) to obtain the "brain agitation effect". The tourmaline composite functional materials and techniques that have direct therapeutic effects on chronic diseases have not been invented.

Summary of the invention

The object of the present invention is to provide a high-efficiency functional composite material having a therapeutic effect on chronic diseases, which can be manufactured into powder, hard solid and soft solids and other solid preparations, and can effectively treat various chronic diseases and is widely used. In the field of health, treatment and rehabilitation of the human body.

The technical scheme of the present invention is as follows:

1. The high-efficiency functional composite of the present invention is made up of the following weight percentages of raw materials:

Tourmaline ultrafine powder and / or crystal infrared material ultrafine powder 66-96%

Mediated strengthening material 0.01-30%

Embedding agent 1-5%

The tourmaline used in the present invention, that is, Tumalinge, is a silicate natural mineral having a permanent electrode and rich in more than 10 kinds of important mineral elements, and is produced in Xinjiang, Yunnan, and other places in China and abroad. Available for sale. The tourmaline according to the present invention is one or more selected from the group consisting of tourmaline, tourmaline, iron tourmaline, and tourmaline.

The crystal infrared material of the present invention is capable of transmitting infrared rays and having different transmittances for different wavelengths of infrared rays, The refractive index and dispersion oxide crystal material is one or more selected from the group consisting of oxide crystals such as AL ₂ O ₃ , Si0 ₂ , MgO, and TiO ₂ , and is commercially available from both domestic and foreign markets. Wherein, Si0 ₂ content of the crystals Si0 _2> 90%, MgO content of MgO _{crystals>90%; AO 3 10%} AL 2 0 3 crystal, content of> 90%, the content of Ti0 ₂ to Ti0 _2> 90% .

The mediated strengthening material of the present invention is a vanillamide-containing alkaloid, and its chemical name is N-(4-hydroxy-3-methoxybenzyl)-8-methylindole-trans-6-enamide. One or more of its homologous analog and derivative compound monomers may be naturally or artificially synthesized, including but not limited to vanillin citrate; sold at home and abroad.

The embedding agent according to the present invention is a mixture of paraffin oil, rosin, methyl cellulose or a combination of any two. For conventional chemical materials.

2. The preparation method of the high-efficiency functional composite powder material of the present invention is -

2. 1 The tourmaline and / or crystal infrared materials are superfinely pulverized by ordinary pulverization and high-speed ball milling. The particle size of tourmaline ultrafine pulverization is <5 μm, and the ultrafine pulverization diameter of crystal infrared material is <500 μm.

2. 2 heat treatment of tourmaline powder and / or crystal infrared material powder, heat treatment temperature 300-1000 ° C, holding time

1-5 hours.

2. 3 According to the ratio of the weight percentage of the present invention, the raw materials are compounded, added to the mixing machine, and stirred and mixed sufficiently.

2. 4 Mix the well-mixed raw materials in a sealed constant temperature drying oven for heating. The heating temperature is 60-200 ° C and the holding time is 1-3 days. That is to become a high-efficiency functional composite powder material.

3. The preparation method of the high-efficiency functional composite soft solid material of the invention is:

3. 1 According to the technical scheme of the present invention 2. 1, 2. 2, 2. 3, 2. 4, the preparation method, complete the preparation of high-efficiency functional composite powder. 3. 2 High-efficiency functional composite soft solid materials are prepared with high-efficiency functional composite powder 20%-60%, soft solid matrix material 40%-80%, wherein the soft solid matrix material is natural or synthetic rubber powder or other soft solid. One or more of the matrix materials.

3. 3 According to the characteristics of the soft solid matrix material, the high-efficiency functional composite powder and the soft solid matrix material are thoroughly mixed by conventional techniques, and then formed into a high-efficiency functional composite soft solid material.

4. The preparation method of the high-efficiency functional composite hard solid material of the present invention is -

4. 1 According to the technical scheme of the present invention 2. 1, 2. 2 Preparation of ultrafine powder of tourmaline and crystal infrared material.

4. 2 According to the weight percentage of the technical scheme 1 of the present invention, the raw materials are respectively weighed.

4. 3 The high-efficiency functional composite powder prepared according to the second aspect of the present invention is further added with a binder of 1-5%, wherein the binder is linseed oil, castor oil, stearic acid, polyvinyl chloride, rosin Any one or a combination of two.

4. 4 According to the technical scheme of the present invention, the prepared raw materials are added to the mixer and then thoroughly mixed.

4. 5 Place the above-mentioned mixed homogenate powder in a mold with a certain shape, press it on a press, and press it at a pressure of 12 - 30 MPa.

It is a high-efficiency functional composite hard solid material.

5. The high-efficiency functional composite (powder, soft solid, hard solid) material prepared by the invention can be used in the fields of human health care, treatment and rehabilitation, and is used as a passive medical device and other medical materials as well as textile materials, daily necessities, etc. Treatment on the surface of human body surface or treatment of sensitive points (acupoints) on the surface of the human body, through internal disease treatment, effectively treating various non-infectious, non-nutritional chronic diseases and improving the quality of life. Alternative to acupuncture, medication and active device therapy. The passive medical device device referred to in the present invention refers to a medical device and equipment that does not require an external power source or a magnetic source. Polar ore tourmaline has spontaneous electrodes, permanent electrodes and electrostatic field phenomena and bioelectrical properties, which can cause bioelectrical effects of the human body.

Crystal infrared materials are capable of transmitting infrared light and have different transmittances, refractive indices and dispersions for different wavelengths of infrared light. It is a light functional material. Infrared materials can be combined with tourmaline to emit high emissivity infrared rays, which can cause a series of physiological effects of the human body.

The mediated augmentation material capsaicin alkaloid activates the cell potential of the human body surface, and activates the membrane potential of the tissue cells in a resting state and the action potential generated by the tissue cells during excitement.

The invention ultrafines the tourmaline and/or crystal infrared material to the nanometer or sub-nano grain size, and the ultrafine particles and the molecules of the mediated strengthening material are mixed, and are embedded in each other by the physical technique of the invention, the material original Some characteristics, the new characteristics of the particles after ultrafine nanocrystallization and the conjugation after embedding and recombination, enable the material of the present invention to produce a node-like agitation effect on the human body surface of the human body.

Both modern western medicine and oriental medicine have proved that the brain is a three-dimensional whole body, and the nervous system is the dominant system of the human body's overall system. Bioelectricity is the spark of human life, which determines the life and death of the human body. The nervous system transmits and feeds information and energy to the human body through a complex network. The smallest structural unit of the nervous system is the neuron (the nerve cell), which contains hundreds of billions of neurons in the body and continues to produce such cells in the future. Each neuron has a cell body that contains the genetic material of the cell; another dendrite, a branch of the cell body that is dendritic to receive information; and an axon, a slender branch of the cell body, The nerve impulse used to conduct the cell body. A single neuron does not have a clear division of tasks, just as a carrier to convey information through current. A neuron has thousands of dendrites that are associated with other neurons to form the body's bioelectrical network. The neurons are very close to each other but not in contact; the gap between each neuron is called a synapse. There are 100 trillion of these synapses on each of us. When the human body is sick, the first is the obstacle in this dominant system, which is embodied in some obstacles in the bioelectric network, and forms sensitive or sensitive points on the human body surface.

The functional material of the present invention, through the agitation of a specific bioelectric network node generated by the invention, imparts extremely fine adjustment to a human body surface (skin or mucous membrane) node or a sensitive point (acupoint) neuron, affecting certain chemicals of the nervous system, capable of Through the synapse of neurons, a certain axon of a neuron in a bioelectrical network is linked to the dendrites of another neuron, and this resistance is removed, causing potential activity on the brain due to its obstruction. Including voltage, speed, rhythm, and synchrony, the influence factors are eliminated, and a "skin brain agitation effect" is realized, so that the disease can be effectively treated and the human body can be recovered.

The functional material of the present invention is used as a medical device or a medical device material to form various medical therapeutic devices and health care devices, and the invention has at least the following six distinct advantages.

1, the treatment is safe. The raw material used in the present invention is a substance which has been proven to be harmless to the human body in the prior art. The functional material of the invention is made into a medical device or a device for treating various chronic diseases, and is a surface treatment of the human body, does not enter the human body, does not cause toxic and side effects to the human body, and can effectively overcome the chronic disease drug in the treatment of chronic diseases which can replace the drug treatment. This worldwide problem of treating toxic side effects.

2. Good operating performance. The medical device and the device made of the functional material of the invention utilize the special properties of the material, It can be used without electricity, no magnetism, no radioactivity, no power supply or other energy source, no electrical components, no damage, no maintenance, and simple operation. It can realize complex treatment principle and simple repeat operation. It solves the problem that the prior art therapeutic instruments need to be active, difficult to maintain and difficult to operate.

3, very durable. The medical device and equipment made of the functional material of the invention can effectively treat 1-2 million times (1 hour for each treatment), and if each person (or family) uses the treatment twice a day, the service life can reach more than 10 years. .

4. Save on treatment costs. The functional materials of the present invention have low production costs and, at the same time, have a long service life, and therefore, the cost per treatment is more than ordinary. If the cost of production and the number of uses are calculated, the cost per treatment is extremely low. This is very beneficial to reduce the high cost of existing drugs for the treatment of chronic diseases and to curb the increase in medical expenses.

5. Applicable broad spectrum of diseases. The functional materials of the invention make therapeutic medical devices and equipments, and because of the novel and unique mechanism of action, the invention can be applied to the rehabilitation treatment of various chronic diseases of non-infective and non-nutritional.

6, the effect is stable and reliable. The functional material of the invention makes a therapeutic device for treating chronic diseases, and the curative effect is stable and reliable. Some of the preliminary validation results are as follows:

(1) A hard solid functional tablet made by the present invention is used to treat brain fatigue effects of students.

1 objects and methods

1. 1 object

The subjects were 120 students with the same physical health status and the third-year university students aged 21-22. 60 male and female girls. Boys weigh 55-65Kg and height 170-180cm; girls weigh 50-55Kg and height 160-167cm. The basic pulse of the subject is between 65-70 beats/sec.

1. 2 methods

After a questionnaire survey, we learned that the brain fatigue caused by continuous learning of these students and the various adverse physiological conditions that affect learning are shown in Table 1.

Table 1 Brain fatigue status questionnaire when students do not self-regulate

Treatment method: The hard solid functional tablet made by the invention is used, and the sensitive point is selected, and the acupuncture position is: the midpoint of the forehead, and the 0.5 inch at the Yintang. During treatment, the functional piece is placed on the fixed acupoint, and the ribbon is tied around the head for one week. One treatment for one hour, two times a day, and one for each afternoon, can be treated in class or study.

2 results

Through functional tablets treatment, once effective, adhere to treatment for 1 month, the recovery effect of brain fatigue state is shown in Table 2.

Table 2: Study on the state of brain fatigue after self-regulation

It can be seen from the table that the difference in learning fatigue time before and after treatment with functional tablets is significant. t=6. 145, P<0.05 (with a=0. 05 as the test for significance). The functional memory was compared 1 hour before and after treatment with functional tablets. The difference was significant, t=10. 104, P<0.05, brain fatigue symptoms, the number of people who developed a symptom after treatment with functional body (such as fatigue) , and the number of people with two or more complications (such as dizziness + vertigo) was significantly reduced.

(2) A clinical study of a hard solid functional tablet prepared by the present invention for treating children with learning difficulties

1 Clinical data

1. 1 Study subjects: Out-of-school children with normal intelligence, but failing to pass grades or teachers as poor students, or poor grades in the previous year due to poor academic performance, and outpatients with behavioral abnormalities. They were randomly divided into treatment group and control group. therapy group

92 people, including 68 males and 24 females, aged 6 years old - 14 years old, average 11 years old; 50 people in the group, 32 males and 18 females, aged 6-16 years, average 11 years old.

1. 2 test tools: using the Chinese Wechsler Children's Intelligence Scale, all subjects were tested twice before and after. Intervals: The treatment group was 30-52 days with an average of 38 days; the control group was 30-60 days with an average of 40 days. The test results were uniformly scored.

1. 3 treatment method: Place the functional piece on the sensitive point of the acupoint (the position of the gods is at the midpoint of the forehead, 0.5 inch on the Yintang hole), tighten the head around the head with a ribbon, each treatment for 1 hour, daily Once in the afternoon and in the afternoon. It can be treated during class time.

2 results

2. 1 Comparison of the measured scores and IQ, memory quotient, and academic scores between the treatment group and the control group. (See Table 1)

Table 1 Comparison of the scores of the two groups of test scores and IQ, memory, and academic scores Tests for the treatment group t test (P value)

Before treatment (1) After treatment (2) Initial test (3) Retest (4) 1: 2 3: 4 1: 3 2:

4

R 7. 43 (2.65) 9.48 (2. 17) 7. 56 (2.87) 7. 32 (3.04) * * NS NS * * Classification 8. 63 (2. 65) 10. 50 (2. 14) 7.44 ( 2. 68) 7. 16 (2.70) * * NS NS * * m 7.87 (3. 12) 10. 28 (2.77) 7.32 (2.25) 7.76 (2.31) * * NS NS * * c 7.96 (2.66) 9. 17 (2.43) 7. 04 (2. 61) 7. 24 (2.09) * * NS NS * * Comprehend 8.13 (2.49) 9. 67 (2.24) 7.92 (3.01) 7. 24 (3.26) * * NS NS * * Emblem 8.00 (2. 37) 9. 11 (1.69) 7.64 (2.48) 8. 32 (2.39) * * NS NS NS* * Fill in Figure 8.02 (3.45) 9.22 (2.42) 7.48 (3.03) 7. 68 (2.91) * * NS NS * Figure 8.73 (2. 38) 10.52 (2. 9) 8.36 (2.64) 8.68 (3.05) * * NS NS * * Weighing 9.20 (2.56) 10.13 (2.38) 8.72 (2.87) 8.28 (3.30) * * NS NS * * Fiber 8.72 (3.05) 10.00 (2.65) 8.64 (2.89) 8.44 (3.84) * * JS *

7.59 (2.68) 9.52 (2.18) 7.20 (3.54) 8.64 (3.13) * * NS NS NS

86.46 (10.40) 96.70 (9.51) 82.88 (14.00) 82.16 (11.71) * * NS NS * *

88.33(13.39) 99.11 (11.43) 85.46 (16.90) 87.48 (17.74) * * NS NS * * Full Machinery 85.91 (9.83) 98.50 (4.77) 82.56 (14.99) 83.34 (13.28) * * NS NS * * Remember! > B 71.71 (12.64) 98.50 (4.77) 79.40 (13.54) 90.00 (15.60) * * NS NS * * Touch 66.61 (12.6) 84.98 (6.36) 67.88 (13.14) 72.38 (9.45) * * NS NS * * Note: * * It means P<0.01, * means P<0.O5, and NS means P>0.05, the same below.

It can be seen from Table 1 that there was no significant difference between the treatment group and the control group at the initial test, indicating that the two groups of subjects came from the same population and were comparable. However, the second test after treatment found that the score of the treatment group was significantly higher than that of the control group, and there was a significant difference by the t test (P<0.05). This was because the treatment group had the first score after the hard solid functional tablet treatment. There was a significant increase in the number of times, while the control group increased the score due to the effect of the exercise, but it was not obvious.

2.2 Comparison of the scores of the two test scores before and after treatment between the treatment group and the control group (see Table 2)

In order to better understand the therapeutic effect and eliminate the influence of the first exercise effect in the second test, we compared the difference scores between the two groups before and after the treatment group and the control group. Significant differences (except for the number of backs, mapping, coding, 3 points, P value > 0.05), and the average of <0.05 or <0.01). In addition, we also found that the severity of the treatment at the beginning of treatment had no significant effect on the therapeutic effect (P< 0.05).

Table 2 Comparison of the scores of the two test scores before and after the two groups

« Treatment group control group P3⁄4

X SD X SD

Knowledge 2.04 2.75 -0.24 2.60 * *

Classification 1.87 1.98 - 0.28 2.17 * *

Arithmetic 2.41 2.53 0.4 2.47 * *

Comprehension L 54 2.47 -0.68 2.78 * *

Vocabulary 1.22 2.16 0.20 2.36 *

Number of parameters 1.11 2.35 0.68 2.48 NS

Fill in the picture 1.20 2.79 0.20 3.73 NS

Row 1.89 2.68 0.32 2.43 *

Building blocks 0.93 1.90 -0.44 2.95 *

Composition 1.28 2.05 -0.20 2.84

Code 1.93 2.15 1.44 3.04 NS

Verbal IQ 11.24 5.97 -0.72 7.52 Water *

Operational IQ 10.78 8.03 1.92 11.58 * *

All IQ 12.2S 4.43 0.68 7.22 Water *

Memory quotient 26.79 11.70 10.60 12.24 *

Grade 18.37 9.59 4.50 16.41 * * (3) The immediate efficacy of 65 cases of heroin-dependent withdrawal symptoms controlled by the functional body made by the invention

1 Clinical data

1. 1 case selection

Heroin was banned in hospital for 72-hour drug users, opioid agonists were used to replace detoxification, and withdrawal symptoms were observed when the dose was decreased. Diagnostic criteria are based on DSM-ΙΠ-R, which meets the criteria for opioid withdrawal syndrome and excludes any other physical or mental or mental disorders.

1. 2-General situation

There were 65 patients in the functional group, including 40 males and 25 females; the youngest was 18 years old, the largest was 38 years old, and the average age was 26.3 years old; the course of drug abuse: 26 cases in 1 year, 31 cases in 1-2 years, more than 2 years 8 cases; drug use: 3 cases of cigarette smoking, 42 cases of scalding, 20 cases of injection; the average daily dose of 1. 36g.

Another 38 patients who underwent drug control for withdrawal symptoms at the same time were selected as the control group. Among them, 20 cases of dihydroetorphine hydrochloride (DHZ) and 18 cases of buprenorphine hydrochloride (BUP); gender: 28 males and 10 females; youngest 18 years old, maximum 48 years old, average age 26.9 years old The course of drug abuse: 12 cases in 1 year, 20 cases in 1-2 years, 6 cases in 2 years or more; Drug abuse: 2 cases of cigarette smoking, 25 cases of scalding, 11 cases of injection, the average daily dose of drug in the last week was 1. 30g.

The treatment group and the control group were basically the same.

2 treatment methods

2. 1 instrument

The functional body produced by the invention can replace traditional acupuncture, massage and modern electrotherapy, magnetic therapy, infrared therapy and chemical therapy.

2. 2 operations

Sensitive point selection prescription: Group 1: Milk (two sides), Yintang, Sun (two sides), Zhongmu, Zusanli (bilateral), Shenmen (two sides)

Group 2: Neiguan (bilateral), Waiguan (bilateral), Hegu (bilateral), Laogong (bilateral), Sanyinjiao (bilateral)

Note: If it is not convenient to use the milk acupoint, you can use sleep (two sides)

Treatment time: Week 1: The two groups of points are used alternately in the morning and afternoon, twice daily.

Week 2: The two groups of acupuncture points are used alternately once a day.

Week 3: Choose one of the two groups of points, once every other day.

When using, directly attach the functional body to the skin of the selected sensitive point, fix it with breathable tape, treat it for 1 hour each time or extend the time according to the symptoms.

3 efficacy criteria

Using the established heroin withdrawal symptom scale, before and after treatment, the doctors registered the score, the withdrawal symptom scale has 23 observation indicators, the score of each indicator is: 0 points asymptomatic; 1 point symptoms are mild or occasional, No treatment is required; 2 points are obvious, requiring treatment but can be tolerated; 3 points are obvious, requiring treatment, unbearable. After the treatment, the onset time was observed and recorded every 5 minutes, and the aging was recorded.

Recent control: drug-seeking behavior, craving for disappearance, symptoms are basically disappeared or mild; withdrawal syndrome scores are less than 8 points. Better: Searching for behavior, hunger is significantly weakened, symptoms are significantly reduced; withdrawal symptoms are between 8-15 points. Invalid: Symptom Before the symptoms are treated, the withdrawal symptoms score is 15 points or more; stealing or switching to other methods to control the addict.

4 treatment results

4.1 therapeutic observation

Among the 65 patients in the treatment group, 36 patients had recent control, accounting for 55.38%. 63 patients were effective, accounting for 96.81%. Compared with the control group, the immediate efficacy was similar (X ² - 0.041, P > 0.05). See Table 1.

4.2 withdrawal symptoms scale integral

Heroin withdrawal syndrome has different clinical manifestations, but at least 4-5 of Table 2 can be diagnosed. The post-treatment scores are shown in Table 2.

Table 1 Comparison of immediate effects between the two groups

Group number of cases, near control, improvement, invalid, efficient

Treatment group 65 36 (55.38) 27 (41.53) 2 (3.09) 96.91

Control group 38 20 (52.63) 16 (42.11) 2 (5.26) 94.74 Table 2 Points of withdrawal symptoms before and after treatment (X soil S)

Abstinence symptoms number of cases before treatment

Yawning 35 1.95±0.67 0.65±0.65

Tears flowing 65 2.09±0.74 1.43±0.67

Fatigue 60 1.87±0.47 1.65±0.82

Irritable 60 1.89 ±0.47 0.55±0.45

Insomnia 40 1.80±0.64 1.10±0.56

Hot and cold 43 2.03±0.63 0.57 soil 0.41

Headache 20 2.00±0.28 0.75 ±0.54

Pain in the body 15 2.22±0.44 1.22±0.58

Chest tightness 18 2.70±0.47 0.83±0.66

Nausea and vomiting 9 2.66±0.52 1.57±0.55

Abdominal pain and diarrhea 9 2.66±0.52 1.65±9.56

Muscle twitching 6 2.00 0

Vertical hair 60 1.90±0.47 0

Cold sweat 38 2.25±0.66 0.55 ±0.48

Skin insect bite 6 2.00 0

Craving 65 2.10±0.76 0

Heart rate is faster 35 1.65±5.24 78.40±3.39

※Heart rate / points

4.3 Comparison of the onset time between the two groups

In the treatment group, the onset time was 15-25 minutes, with an average of 5.90±4.85 points; the drug DHE group was effective, with an average of 10.75.

± 2.93 points; drug BUP has a slower onset, with an average of 27.22 ± 3.52 points. See table 3.

Table 3 Comparison units of the two groups of onset time: Example (%) Control group

Time (minutes) treatment group DHE BUP

"5=Ίϋ 18(27.69) 15(75.00) =

11-15 25(38.46) 5(25.00) ——

16-20 15(23.07) —— 2(11.11)

21-25 7 (10.76) —— 6 (33.33)

26-30 —— —— 10 (55.56)

4.4 The relationship between the efficacy of the treatment group and the course of drug abuse

The course of drug abuse is better in 2 years, and the effect is slightly worse in 2 years or more. See table 4.

Table 4 Relationship between efficacy and abuse time Unit: Example (%)

Time number of cases near control m 3⁄43⁄4

<1 year 26 16 (61.5) ^ 10 (38.5) 0

1-2 years 31 19 (61.3) 12 (38.7) 0

>2 years 8 2 (25.0) 4 (50.0) 2 (25.0)

―" ·3⁄4 -^? KX ² =0.026 ~~ Ρ>0.05,※~※※※^.34 Ρ=0.05

The reason for this is that persistent withdrawal symptoms can persist for varying degrees of time and mentally dependent symptoms for a longer period of time, and the lack of effective and non-addictive drugs during the rehabilitation phase leads to relapse after detoxification.

This data was observed by functional body treatment in 65 cases, with a recent control rate of 55.38% and an effective rate of 96.91%, suggesting an effective method for the treatment of rehabilitation.

5.1 Evaluation of clinical efficacy

Both the treatment group and the control group can control the onset of withdrawal symptoms, and the immediate effects are similar. Drug DHZ is an opioid receptor agonist, which has a strong substitute for heroin. BUP is an opioid receptor semi-agonist and semi-antagonist, which can partially replace heroin. However, the former has obvious physical and mental dependence and should not be used for a long time. The latter has a small adverse reaction, but it also has the disadvantage of addiction, which limits the use time of drug addiction. The treatment with the functional body of the invention belongs to the surface effect therapy of nano materials, has no adverse reaction, is safe, and is not addictive to repeated treatment.

From Table 2, the withdrawal symptom score score: the average score of withdrawal symptoms before treatment was 34.12, 13.07 after treatment, and the difference was 21.05. There was significant difference before and after treatment (t=4.91 P<0.01). The scale suggested that the treatment group Inhibition of sympathetic nerve excitability has a significant effect, manifested as vertical hair, cold sweat, skin insect bite, craving for symptoms disappeared, heart rate increased in 35 cases, the average reduction of 13.25 times.

5.2 Evaluation of onset time

Table 3 shows that the onset time of the treatment group was 15 points, accounting for 38.63%, the fastest 3 cases were effective for 5 minutes, and the slowest was 25 minutes, which was related to individual differences. That is to say, the meridian sensitivity of the bioelectric network is different, so the effect is different. DHZ works quickly, mostly in 10 minutes, accounting for 75.0°/. BUP has a slower effect, which is mostly in 30 minutes, accounting for 55.56%. From this point of view: The functional body of the invention has less effective time than DHZ, but faster than BUP.

5.3 Analysis of efficacy and abuse time

The history of drug abuse is obvious in 2 years, and the immediate effect is worse in those with more than 2 years, which is consistent with drug addiction. When the drug use time is long, the dosage is increased. Domestic scholars have found that: drug users have normal or mild superoxide dismutase activity within half a year. Rising, the longer the history of drug abuse, the lower the level of vitality and the decrease in cellular cAMP levels. The history of drug abuse in two of the 65 patients was 6 years and 28 years, which may be related to the decrease of enzyme activity, damage to the body's antioxidant defense system, and decreased antioxidant capacity.

(4) The functional body made by the invention treats vertigo in 54 cases

1. Clinical data

Of the 54 cases, 24 were outpatients and 30 were hospitalized; 21 males and 33 females; the youngest was 17 years old, the largest was 87 years old, with an average of 50 years; the shortest course was 0.5 days, the longest 21 years, the average was 2. 2 years. . There were 25 cases of cerebral arteriosclerosis, 10 cases of hypertension, 8 cases of cervical spondylosis, 14 cases of Meniere's syndrome, 2 cases of climacteric syndrome, 3 cases of hyperviscosity, 2 cases of neurasthenia syndrome, brain trauma. There were 1 case of sequelae and 2 cases of chronic alcoholism. All cases were mainly vertigo.

2, treatment

All cases were treated with functional body, and sensitive points were selected:

Main points: Baihui, Sun, Neiguan, Zusanli.

Acupoints: Kidney yin deficiency, plus Taixi, Shenshu; qi and blood deficiency, plus sputum, spleen; turbidity in the middle of the block, Fengshu, spleen; Fengyang on the discretion plus Tai Chong, wind pool.

Operation: Use the special function of vertigo to care for the main point and add points according to the syndrome differentiation. At the time of treatment, after selecting the acupoints, stick the functional body treatment surface to the acupuncture points, fix it with a breathable tape, and take it off after 1 hour of treatment.

3, treatment results

Of the 54 cases, clinical cure (symptoms completely disappeared, able to participate in work and life normally) 43 cases; improved (symptoms were significantly reduced) 38 cases; ineffective (no significant changes before and after treatment) 2 cases. Total effective rate 96. 2%. The average healing time is 18 days.

(5) Clinical observation of 50 cases of stroke sequelae treated by functional body made by the invention

1. General information

Of the 50 patients, 38 were male and 12 were female. The age of onset was 33 years old, the largest was 76 years old; the shortest course was 2 weeks, the longest was more than 1 year; 46 cases were within 3 months, and 4 cases were more than 3 months. According to the lesion, there were 30 cases of cerebral hemorrhage and 20 cases of cerebral embolism.

2, treatment

2. 1 Acupoints for sensitive points: Shuigou, Neiguan, Laogong, Quchi, and Venezuela. Half-length person with shoulders, Hegu, Waiguan, Huanqiu, Yanglingquan, Zusanli, Xiexi, Kunlun, Taichong; mouth and eye slanting plus warehouse or cheek car, Hegu, inner court, Chengqi, Yangbai, 攒Bamboo, Kunlun, old-age care; language disadvantaged plus Lianquan, Tongli, Yamen, Fengfu, Tiantu, Sanyinjiao.

2. 2 Method: After selecting the sensitive acupuncture points, the functional body is attached to the selected sensitive points, and fixed with a breathable tape or a special elastic band. Each time for 1 hour, each time with 4-5 points, the acupuncture points of each group are used alternately. . 1 time, 1 time, 10 times for 1 course of treatment; 1 day after the end of the course of treatment, rest for 2 days and then 1 course of treatment.

3, the standard of efficacy

Clear speech, can walk alone, upper limbs can hold high and hold objects, life can take care of themselves, self-feeling and ordinary people are better than others; words are clearer, can walk alone, upper limbs can hold things but feel weak, life can basically take care of themselves, The occasional discomfort of the limb is markedly effective; the speech is unfavorable but can express the basic meaning, the upper and lower extremity muscle strength is enhanced but the function recovery is not good, and the life still needs the care of others; the person who has no obvious change before and after treatment is invalid.

, Clinical efficacy

The recovery of 17 cases accounted for 34%; the effective cases of 16 cases accounted for 32%; the effective cases of 12 cases accounted for 24%; the invalid cases of 5 cases accounted for 10%. The total effective rate is 90%. Among them, at least 1 course of treatment and up to 9 courses of treatment. Average treatment 3. 8 courses of treatment.

The relationship between disease course and curative effect is shown in Table 1.

The relationship between disease position and curative effect is shown in Table 2.

Table 1 Table of relationship between efficacy and disease

Cases of recovery effective and effective cases ( ) Case (%) Case (%) Case (%) Cerebral hemorrhage 30 10 ( 35) 12 (40) 6 (18. 33) 2 (6. 67) Cerebral embolism 20 6 ( 31 5) 4 (20) 7 (33. 5) 3 ( 15)

Table 2 Relationship between efficacy and disease duration

The number of cases is effective, effective, invalid

Case example

Bu March 46 15 15 12 4

March or more 4 1 2 1

(6) Therapeutic effect of functional body made by the present invention on constipation-type irritable bowel syndrome

, Materials and Methods

1. 1 clinical data

In the digestive clinic, 50 cases of constipation-type irritable bowel syndrome were treated by laboratory examination. The lower digestive tract sputum angiography and colonoscopy excluded the systemic diseases and intestinal diseases caused by constipation. Meeting standard. There were 18 males and 32 females, the oldest 63 years old, the youngest 15 years old, and the average age was 37 years old. The longest course was 20 years, the shortest half year, and the average disease duration was 5 years.

1. 2 syndrome differentiation

Mainly divided into two types, namely liver qi stagnation type and heart and spleen deficiency type. Liver qi stagnation type: dry or not dry stool, difficult to resolve bowel movements, less than 3 times a week, even 1 week 1 solution, abdominal pain and even two threats, mouth pain, dizziness, symptoms with mood fluctuations, tongue Light, thin white fur, weak and weak.

Fifty patients had liver qi stagnation type in 21 cases, accounting for 42%; heart and spleen deficiency type in 29 cases, accounting for 58%.

1. 3 treatment methods

All patients were psychologically counseled to eliminate mental symptoms such as anxiety and depression; adjust personal diet, increase plant fiber content in diet; develop regular bowel habits, change bad habits such as smoking and reading during defecation; Then, based on this, the sensitive points are dialected to perform the functional body treatment of the present invention. The basic side is bilateral large intestine Yu, Zusanli and Zhongyu. Liver qi stagnation type plus bilateral Yanglingquan, inter-line, heart and spleen deficiency type plus bilateral Sanyinjiao and Guanyuan. Select the functional body during treatment, apply the functional body to the selected sensitive point for 1 hour, use elastic With or with a breathable tape. 1 course every 10 days, once a day; 2 courses per treatment, 2 days in the middle, the observation period is two months.

, efficacy evaluation criteria and results

2. 1 efficacy evaluation criteria

Significant effect: Clinical symptoms disappeared, bowel movements were normal, and there was no recurrence in two months. Effective: Significant improvement in clinical symptoms, normal bowel movements, recurrence within two months. Invalid: There is no significant improvement in clinical symptoms and defecation, or medication is required. 2. 2 results

Fifty patients had markedly effective liver qi stagnation in 15 cases, effective in 4 cases, and ineffective in 2 cases; heart and spleen deficiency type was markedly effective in 16 cases, effective in 9 cases, and ineffective in 4 cases. A total of 31 cases (61%) were effective, 13 cases (26%) were effective, 6 cases (12%) were ineffective, and the total effective rate was 88%.

(7) The functional body made by the invention treats 66 cases of hypertension

, clinical information

There were 66 cases in this group, including 41 males and 35 females. There were 1 case of those under the age of 45, 22 cases of 45 cases to 55 years old, and 42 cases of those over 55 years old. The shortest course of the disease is half a year, and the longest is 9 years. The blood pressure diagnosis standard is implemented according to the WHO diagnostic criteria stipulated in the 1978 National Conference on Cardiovascular Diseases. There were 12 cases in stage I, 47 cases in stage I, and 7 cases in stage III.

Treatment methods: 1 sensitive points: Dazhui, Neiguan, Jiangyan, Taichong, Hegu, Fengchi (both sides), Ganshu, Baihui.

, method:

When treating with the functional body made by the invention, the functional body is attached to the acupuncture points of the selected sensitive points, and is fixed by elastic band or gas permeable tape, and each treatment is for 1 hour, 4-5 times for each use point, and the acupuncture points of each group are alternated. Use, once a day, every 10 times for a course of treatment. During this period, you must quit smoking and alcohol, be cautious, keep your urine and urine open, and stop using any treatment.

Efficacy criteria and results: 66 cases were observed for half a year, cured (47 cases): headache, dizziness symptoms disappeared, blood pressure decreased to normal, no recurrence after 6 months of follow-up; markedly effective (18 cases): headache, dizziness and other symptoms disappeared, blood pressure dropped to normal Recurrence within half a year; effective (6 cases): headache, dizziness, blood pressure, fluctuations in normal values and critical hypertension (5 cases): symptoms are relieved, blood pressure does not drop, or falls below normal range. The total effective rate is 92% and the cure rate is 71%.

(8) The functional body made by the invention treats 50 cases of coronary heart disease

, clinical information

Of the 50 patients, 37 were male and 13 were female; the oldest was 76 years old, the youngest was 23 years old, 8 cases were 40-49 years old, 20 cases were 50-59 years old, 16 cases were 60-69 years old, and 3 cases were 70-79 years old. Western medicine clinical classification, 17 cases of angina pectoris, including 16 cases of stable labor angina pectoris, 1 case of unstable angina pectoris; 15 cases of arrhythmia, including 10 cases of ventricular premature beats, 2 cases of premature atrial contraction, 1 case of sick sinus syndrome, room 1 case of fibrillation, 1 case of complete right bundle branch block; 9 cases of myocardial infarction; 11 cases of old myocardial infarction. The clinical classification of TCM was 13 cases of blood stasis type, 11 cases of turbidity type, 8 cases of qi stagnation type, 7 cases of qi deficiency type, 11 cases of qi and yin deficiency type, and 5 cases of heart yang deficiency type.

, treatment method

Sensitive points take acupuncture points to the specific acupoints of the functional body, and the heart and the pericardium are mainly based on Yu's acupoints. Pericardium through the acupoints, group 1, giant scorpion, Xinshu, Yushu, Neiguan, Gongsun, yin; the second group, Suizhong, Yuyin Yu, Sanyinjiao, Tuen Mun. The two groups are used alternately, turbidity plus Taiyuan: deficient cold plus sputum or sputum.

When using functional body therapy, the functional body can be applied to the selected sensitive points for 1 hour, once a day, 10 times for a course of treatment, and generally observed for 3 courses.

Efficacy criteria 1. The standard of angina pectoris and electrocardiogram was based on the National Standards for Assessment of Angina Pectoris and Electrocardiogram in 1979. 2. The main symptom efficacy criteria (including chest pain, palpitations, shortness of breath 3): markedly the symptoms disappeared completely or disappeared; improved as symptomatic procedures were significantly reduced; invalid symptoms were basically the same as before treatment; aggravated symptoms worsened than before treatment . 3. The standard of blood lipids is based on the standards set by the Shanghai Compound Danshen Collaborative Group in 1974.

Treatment results: 1 The efficacy of each main symptom (see Table 1)

2 The efficacy of TCM syndrome differentiation (see Table 2)

3 blood lipid efficacy: total cholesterol was 30 cases, 23 cases were effective; triglyceride was high in 20 cases, 10 cases were effective.

Table 1 main symptoms and efficacy statistics

The number of main symptoms is markedly improved, invalid, aggravated, effective (%)

Chest pain 30 20 6 2 2

Chest tightness 32 12 16 4 0 87. 50

Heart 俸 23 10 8 5 0 78

Shortness of breath 13 5 7 1 0 92

Table 2 TCM syndrome differentiation and efficacy statistics

Number of cases, number of cases, improvement, invalid

Bloody 13 8 4 1

Turbidity 11 5 5 1

Gas lag 8 2 4 2

Heart qi 7 3 3 1

Qi and Yin deficiency 6 3 2 1

Heart yang 5 2 2 1

4 ECG changes: Where there is ST-T change, V wave changes, atrial fibrillation, sick sinus, frequent ventricular premature beats, frequent premature atrial contractions, complete right bundle branch conduction and conduction resistance are improved.

5 heart function: Anyone who has abnormal heart function has a good deed. Results LVET prolonged, PEP, TICT shortened, and the value of PEP/LVET decreased.

(9) Functional body made by the invention for treating 76 cases of senile dementia

normal information

There were 46 males and 30 females in 76 cases; the age ranged from 59 to 78 years old, with an average of 73 years; the course of disease was 9 months to 8 years, with an average of 2 years and 8 months.

treatment method

Sensitive points are taken from Baihui, Sishencong, Dazhui and Guanyuan. After fully functionalizing the functional body surface and the acupoint skin surface with the functional body prepared by the invention, the functional body is attached to the selected sensitive point, and then the elastic band or the gas permeable adhesive cloth is used for fixing. Set. The acupuncture points on the head are fixed with a synergistic membrane. Each treatment for 1 hour, once a day, 10 times for a course of treatment, general treatment for 2-3 months. Rest 2 days between each course of treatment. Patients can continue to use antihypertensive, lipid-lowering, hypoglycemic, and anti-platelet aggregation drugs during treatment.

treatment effect

Efficacy criteria: Basic recovery: Symptoms disappear, self-care, can carry out normal social interaction activities; Significant effect: Symptoms improve, but slow response, mental and personality disorders, life can not take care of themselves; Ineffective: No change before and after treatment.

After treatment, the results were basically cured in 7 cases, markedly effective in 33 cases, effective in 26 cases, and ineffective in 10 cases. Of the 19 patients with a course of <1 year, 6 were basically cured, 9 were markedly effective; those with ineffective treatment were all > 3 years. The effective rate is 86%.

(10) The functional body made by the invention treats 64 cases of chronic enteritis

1. General information

There were 64 cases in this group, 38 males and 26 females, including 8 cases of 30-40 years old, 18 cases of 41-50 years old, 26 cases of 51-60 years old, and 12 cases of 61 years old and above; the shortest course was 1 year, the longest 12 years. Diagnosis basis: 1 history of acute inflammatory bowel disease or repeated episodes; 2 onset, diarrhea, abdominal pain, etc., patients may have chronic malnutrition, physical examination may have abdominal tenderness, white blood cells, cells and a small number of pus cells can be seen routinely. 3 X-ray barium examination and colonoscopy to exclude other non-specific intestinal inflammation.

2, treatment

2. 1 Sensitive point acupoints Umbilical Week 4 points, Zhongmu, Tianshu, Guanyuan, Zusanli, Shangjuxu, Shenshu, Pishu, Dachangshu, Quchi, Sanyinjiao.

2. 2 methods The upper holes are divided into two groups. The first group: Umbilical Thursday, Zhongmu, Tianshu, Guanyuan, Zusanli, Shangjuxu, Hegu, Sanyinjiao; Group 2: spleen, Shenshu, Dachangshu, Zusanli, Shangjuxu, Hegu . The acupuncture points of the two groups are alternately used every day. The functional body of the present invention is used, and it is attached to the acupuncture points of the selected sensitive points, 4-5 acupuncture points each time, and fixed by air-permeable tape, each treatment for 1 hour. 10 times for 1 course of treatment.

3, treatment results

Efficacy criteria Recovery: stool formation, 1 time a day; improved: stool formation, 2 times a day; Ineffective: no significant changes before and after treatment. Among the 64 cases, 31 cases were cured, accounting for 48.4%; 28 cases were improved, accounting for 43.7%, and 5 cases were ineffective, accounting for 7.9%. The total effective rate is 92. 1%.

(11) Therapeutic effect of 68 cases of chronic prostatitis treated by the functional body made by the invention

1. Clinical data

In this group of 68 patients, most patients have received Chinese and Western medicine treatment. The youngest is 17 years old, the largest is 76 years old, 3 cases are under 20 years old, 5 cases are 21- 30 years old, 31- 40- 8 cases, 17 cases are 41-50 years old, 35 cases are over 50 years old; the shortest course is half a year, the longest is 20 years . 57 were married and 11 were unmarried. Most patients complained of soreness in the lumbosacral region, swelling of the lower abdomen and perineum, frequent urination, poor urination, and incomplete leaching. Among them, 6 patients had severe neurasthenia and sexual dysfunction. Prostatic fluid microscopy: white blood cells (+) in 28 cases, (++) in 21 cases, (+++) in 15 cases, and (++++) in 4 cases. There were 32 cases of prostatic hypertrophy and 2 cases of prostatic stones.

2, treatment

2. 1 sensitive point acupoint

Main points: small intestine Yu, bladder Yu, spleen, sputum, Guan Yuan, Zhongji. Matching points: Yinlingquan, Sanyinjiao, too Creek. Empirical plus bones, foreign customs, deficiency syndrome plus Shenshu, Zusanli.

2. 2 operations

The acupoints in the prone position are attached to the acupuncture points of the selected sensitive points by the functional body of the present invention, and are fixed by elastic bands or breathable tapes, and each treatment is performed for 1 hour, and the functional body can be removed after the treatment.

The above treatment is performed once a day, each time taking 4-5 of the main and matching points, and alternately selecting. A course of treatment every 10 days, rest 3-5 days between treatments.

Observation of curative effect

3. 1 efficacy standard

Cure: Conscious symptoms disappear, prostatic fluid microscopy is normal; Significant effect: Conscious symptoms disappeared, no more than 3 white blood cells in prostatic fluid at high magnification; Improved: Significantly relieved symptoms, 4-6 of white blood cells in prostatic fluid at high magnification; Invalid: There were no significant changes in the symptoms and prostatic fluid tests.

3. 2 treatment results

After 68 cases of treatment, 68 cases were cured, accounting for 26.55; 21 cases were markedly effective, accounting for 30.99%; 22 cases were improved, accounting for 32.3 %; 7 cases were ineffective, accounting for 10.3%. The effective rate was 89.7 per cent.

Comparison of the efficacy of patients of different ages is shown in Table 1.

Table 1 Comparison of patient effects at different ages

Age number of cases, recovery, effectiveness, improvement, invalidity, efficiency (%)

17-20 years old 3 1 2 - - -

21-30 years old 5 3 1 1 - -

31-40 years old 8 4 2 2 - -

41-50 years old 17 6 7 3 1 94. 1

50-76 years old 35 4 9 16 6 82. 9

(12) The functional body made by the invention treats 36 cases of trigeminal neuralgia

1. Clinical data

The group treated a total of 56 patients, including 20 males and 36 females; the oldest 78 years old, the youngest 35 years old; the first pain 5 cases, the second pain 15 cases, the third pain 16 cases; the composite type 20 cases The course of disease was as short as 1 month and the longest was more than 10 years; 48 cases were primary and 8 cases were secondary. There were 3 cases of cholesteatoma and 5 cases of post-herpetic neuralgia. , treatment method

Sensitive points for acupoints: the first pain is taken from the waist of the fish, and the lower part is mainly used. It can be used with points such as Yangbai, Shangxing, Hegu, and Inner Court. Second, three pains take four white, Shimonoseki, the warehouse, the folder, the Hegu, the inner court and so on. The acupuncture points on the head and face are taken from the affected side; The functional body made by the invention is applied to the sensitive point, once a day, 10 times for a course of treatment, rest for 3-5 days, and the next course of treatment can be continued.

Observation of curative effect

Efficacy criteria: The treatment of the posterior part of the pain completely disappeared as a clinical cure; the facial pain and the number of episodes decreased significantly; the facial pain and the number of episodes decreased; the treatment of posterior pain and the number of episodes were not effective.

Treatment results: 38 patients in this group had oral carbamazepine tablets before treatment, and stopped taking the drug after treatment for a period of time. The functional body prepared by the present invention was not treated during the treatment. 18 patients who did not take the drug Functional body treatment with carbamazepine tablets 0. lg, 2 times a day. The functional body prepared by the present invention is treated at least 6 times and at most 20 times. 42 cases were cured clinically, accounting for 75%; 9 cases were markedly effective, accounting for 16.1%; 5 cases were improved, accounting for 8.9%; 0 cases were ineffective; the total effective rate was 100%. Among them, 42 cases had no recurrence within 6 months of follow-up, and 11 cases relapsed within 3 - 4 months, but the symptoms were mild. The symptoms disappeared after 5-10 treatments of the functional body of the present invention. Three patients with cholesteatoma were transferred to hospital for treatment after symptom reduction, and no follow-up was performed.

(13) 120 cases of general headache treated by the functional body made by the invention

, clinical information

Among the 120 patients in this group, 39 were male and 81 were female; the youngest was 20 years old and the oldest was 70 years old; the short illness was 5 hours and the longest was 20 years.

, treatment method

2. 1 Acupoints for sensitive points The main points are Fengchi and Baihui, and according to clinical syndrome differentiation, they are equipped with different acupoints. Clinically, there are many types of external sensation, liver yang and blood stasis. (1) Exogenous type: The headache is caused by the wind, and the pain is more dramatic. It is accompanied by Fengfu, Lie, Waiguan and Hegu. (2) Liver-yang type: The head horn is sore, mostly on one side, or even on the dome, with the points of Sishencong, Taichong and Shuiquan. (3) Blood type: pain such as cone thorn, long-term unhealed, with Sanyinjiao, Ashi points.

2. 2 methods of operation

Use the functional body made by the invention, stick it on the skin of the selected sensitive point, fix it with loose band or breathable tape, treat it for 1 hour each time, treat once a day, 10 times for 1 course, rest during treatment 2 Days, statistical effects after 1 course of treatment.

Observation of curative effect

3. 1 Efficacy criteria Healing: Pain symptoms disappear completely, no recurrence for more than half a year; Significant effect: Pain is significantly reduced, the number of seizures is significantly reduced; Effective: Pain is reduced, the number of seizures is reduced; Invalid: Pain symptoms are not improved after treatment.

3. 2 Treatment results Among the 120 patients, 96 cases were cured, accounting for 80%; 18 cases were markedly effective, accounting for 15%; and 6 cases were effective, accounting for 5%. Effective 100%.

(14) The functional body made by the invention treats 50 cases of gastric and duodenal ulcer

, objects and methods

1. 1 Case selection: The selected 80 hospitalized patients were in accordance with the diagnostic criteria for gastric and duodenal ulcers. They were randomly divided into two groups, 50 patients in the treatment group, including 35 males and 15 females; aged 24-62 years, mean (35. 5± 11. 3) years; disease duration 0. 5- 20 years, average (6. 4±2. 8) years; 19 cases of gastric ulcer, 26 cases of duodenal ulcer, 5 cases of compound ulcer; 44 cases of negative occult blood test. 4 cases were weakly positive and 2 cases were positive. 30 patients in the control group, including 18 males and 12 females; aged 20-68 years, mean (34.4 ± 12. 4) years; duration of disease 4 months - 18 years, average (6.5 ± 3. 0) Years; 10 cases of gastric ulcer, 13 cases of duodenal ulcer, 7 cases of compound ulcer; 25 cases of negative fecal occult blood test, 3 cases of weak positive, 2 cases of positive. There was no significant difference between the two groups by X ² statistical treatment (P>0.05), which was comparable.

1. 2 treatment methods: treatment group sensitive points acupoints: the first group to take Zusanli, Neiguan, Gongsun; the second group to take Zhongyu, spleen, stomach Yu. Stomach pain is even more plus Liangqiu, stomach cold is added to the lower jaw, abdominal distension is even more Tianshu, acid reflux is too rushing, then Secret plus sulcus, insomnia plus the door, weak and refueling the sea. The above two groups of acupoints are used alternately, once a day, using the functional body made by the present invention, and sticking it on the selected sensitive point, and fixing it with air-permeable tape for 1 hour and 10 times for one course of treatment. After 2 months, the gastroscope was reviewed. Acupuncture points in the control group: The acupoints are the same as above, but the common acupuncture needles are used to replenish the diarrhea. Ulcer bleeding (mild) can aid medication.

1. 3 observation items: ulcer surface (with gastroscopy results as standard), some clinical symptoms (abdominal pain, acid reflux). 1. 4 Evaluation criteria for efficacy: Refer to the “Diagnostic and Efficacy Standards for TCM Disorders” issued by the State Administration of Traditional Chinese Medicine in 1994. Clinical cure: Gastroscopic examination of the ulcer surface has healed, clinical symptoms disappeared or disappeared; markedly effective: gastroscopic examination of the ulcer surface was significantly reduced or entered the scar period, clinical symptoms basically disappeared or significantly reduced; improved: gastroscopic examination of the ulcer surface did not shrink, but Gastric mucosal congestion and edema improved, clinical symptoms were alleviated; Ineffective: No change before and after treatment (no change in ulcerated surface by gastroscopy, no improvement in clinical symptoms).

Result

See Table 1, 2.

Table 1 Comparison of the two groups of efficacy

Table 1 Comparison of the two groups

Group number of cases, cure, effectiveness, improvement, invalid, total efficiency (%)

Treatment group 50 14 11 21 4 92. 0°

Control group 30 6 6 13 5 83. 3

Table 2 Comparison of time required for curing cases in both groups

Group number of treatments

6 7 8 9

Treatment group 14 2 5 5 2

Control group 6 0 0 2 4

(15) 120 cases of vascular headache treated by the functional body made by the invention

1. Clinical data

In this group of 120 patients, 35 males and 85 females; the youngest is 18 years old, the largest is 76 years old, the shortest course is ld, the longest is 10 years.

2, treatment

Acupoints for sensitive points: divided into four groups: the first group of points: Yintang, Yongquan, Hegu; The second group of points: Yintang, Fengchi, Zhongli; The third group of points: Neiguan, hurricane, sun, full headache plus Around the hair circle; the fourth group of wind pools, Neiguan, the sun, the rate valley.

Method: The functional body prepared by the invention is attached to the acupoint surface of the sensitive point, and fixed with an elastic band or a breathable adhesive tape. Each treatment is for 1 hour, 10 days is a course of treatment, and the treatment rests for 2 days, and the therapeutic effect is evaluated after 2 courses of treatment.

3, efficacy observation and results

Clinical cure: After treatment, the pain disappears, return to normal work and life, no recurrence after 6 months of follow-up; markedly effective: After treatment, the pain disappears, return to normal work and life, relapse within half a year; Effective: After treatment, winter pain relieves, tired, When the anger is aggravated, there is a recurrence; Ineffective: The pain is not relieved after treatment.

Among the 120 cases, 85 cases were cured, 20 cases were markedly effective, 12 cases were effective, and 3 cases were ineffective. The total effective rate was 97.5%. detailed description

Example 1

The composition (weight percentage) of the prepared high-efficiency functional composite is: tourmaline ultrafine powder 56%, crystalline infrared material ultrafine powder 40% (including Si0 ₂ crystal 20%, Si0 ₂ crystal content >90%, MgO crystal 10%) , MgO crystal content >90%, AL ₂ 0 ₃ crystal 10%, AL ₂ 0 ₃ crystal content >90%), mediated strengthening material 2% (for synthesis of succinic acid vanillamide, 70% content), embedded 2% (including paraffin oil 1%, rosin 1%). The tourmaline ultrafine powder has a particle size of 100 nm, and the crystalline infrared material ultrafine powder has a particle size of 500 nm.

Among the above ingredients, tourmaline ultrafine powder is purchased from the market for high quality tourmaline ore, which is subjected to ordinary pulverization, followed by high speed ball milling and subsequent heat treatment. The high-speed ball milling time is 80 hours, the heat treatment temperature is 900 ° C, and the holding time is 2 hours. The crystal infrared material is purchased from the market through ordinary pulverized powder raw materials, subjected to idle ball milling, and then heat treated. The high-speed ball milling time is 50 hours, the heat treatment temperature is 800 ° C, and the holding time is 2 hours.

The above ingredients are put into the V-type mixing mixer, fully stirred, mixed and fully hooked, placed in a sealed constant temperature drying oven, and heated, the heating temperature is 140 ° C, and the holding time is 1 day, ie It is a high-efficiency functional composite powder material for human health care, rehabilitation, treatment and quality of life.

In the embodiment 1, the intensive enhancer material is 2%, which is a weaker strength, and is used for acupuncture treatments sensitive to the human body, such as Shenque (umbilical) treatment or acupuncture treatment of head and neck.

Example 2

High efficacy functional composition formulated composite material (by weight) of: 55% ultrafine tourmaline, 40% crystalline superfine infrared materials (including crystals Si0 ₂ 20%, Si0 ₂ crystal content> 90%, MgO 10% crystalline , MgO crystal content > 90%, AL ₂ 0 ₃ crystal 10%, AL ₂ 0 ₃ crystal content > 90%,), mediated strengthening material 3% (for the synthesis of n-antimonic acid vanillamide, 70%), package The embedding agent is 2.0% (including paraffin oil 1%, rosin 1.0%), wherein the tourmaline ultrafine powder has a particle size of 90 nm, and the crystalline infrared material ultrafine powder has a particle size of 450 nm.

Among the above ingredients, tourmaline ultrafine powder is a tourmaline ore originally purchased from the market, which is firstly pulverized, then added to a high speed ball mill ball mill, followed by heat treatment. The high-speed ball milling time is 80 hours, the heat treatment temperature is 900'C, and the heat preservation time is 2 hours. The crystal infrared material is a common powder raw material purchased from the market, and is also added to a high-speed ball mill ball mill, followed by heat treatment. The ball milling time was 50 hours, the heat treatment temperature was 800 ° C, and the holding time was 2 hours.

In addition to the binder, the above ingredients are put into a V-type mixing mixer, mixed and stirred, and then fully mixed and hooked, placed in a sealed constant temperature drying oven, and subjected to heating treatment at a heating temperature of 150 ° C. , holding time 2 days.

Then weighed 3% of the total weight (including 1.5% of stearic acid and 1.5% of polyvinyl chloride), and then put the prepared powder and binder into the mixer and mix well. Evenly.

The powder prepared by the above process was placed in an octagonal mold, and pressed into an octagonal sheet shape on a press having a diameter of 3 cm, a thickness of 0.3 cm, and a pressing force of 24 MPa.

The prepared sheet-like hard solid is a high-efficiency functional composite hard solid material, which can be used for rehabilitation equipment and equipment for human health and chronic diseases.

The high-efficiency functional composite hard solid material prepared in this Example 2 can be used as a hard solid functional tablet used in the above clinical effects. The hard solid functional sheet used in the above clinical effects may be in the form of an octagonal sheet prepared as described above, having a diameter of 3 cm and a thickness of 0.3 cm. In the second embodiment, the 3% of the reinforcing agent material is a slightly stronger strength, and is used for the general sensitive acupoint treatment of the human body, such as body acupoint treatment.

Example 3

The composition (weight percentage) of the prepared sputum therapeutic functional composite is: tourmaline ultrafine powder 52%, crystalline infrared material ultrafine powder 40% (where SiO ₂ crystal 20%, Si0 ₂ crystal content > 90 ° /., MgO crystal 10%, MgO crystal content >90%, AL ₂ 0 ₃ crystal 10%, AL ₂ 0 ₃ crystal content >90%), mediated strengthening material 5% (for the synthesis of n-carboxamide, 70%) The embedding agent is 3% (including paraffin oil 1.5%, rosin 1.5%). The tourmaline ultrafine powder has a particle size of 80 nm, and the crystalline infrared material ultrafine powder has a particle size of 500 nm.

Among the above ingredients, tourmaline ultrafine powder is purchased from the market for tourmaline ore, which is subjected to ordinary pulverization, and then into a high-speed ball mill for ball milling, followed by heat treatment. The ball milling time is 80 hours, the heat treatment temperature is 900 ° C, and the holding time is 2 hours. The crystal infrared material is purchased from the market, then subjected to high-speed ball milling, followed by heat treatment. The high-speed ball milling time is 50 hours, the heat treatment temperature is 800V, and the holding time is 2 hours.

The above ingredients are put into the mixer, fully stirred, and mixed thoroughly, and then placed in a sealed constant temperature drying box for heating treatment, the heating temperature is 150 ° C, and the holding time is 2 days.

Take 50% by weight of the powder raw material produced by the above process, and take 50% by weight of the synthetic rubber powder, put it into the rubber mixer, mix the high-efficiency functional composite powder with the rubber powder, and process it into a high-efficiency function according to the ordinary rubber process. Composite rubber mud. The compounded rubber mud is a high-efficiency functional composite soft solid material, which can be used for human health care and chronic diseases, rehabilitation equipment and equipment, and beauty and body to improve the quality of life.

In the third embodiment, the 5% of the reinforcing agent material is a strong intensity, and is used for acupoint treatment of the human body, such as limb acupoint treatment.

The high-efficiency functional composite soft solid material prepared in this Example 3 can be used as the functional body used in the above clinical effects. The functional body used in the above clinical effects is a circular sheet having a diameter of 3 cm and a thickness of 0.2 to 0.3 cm.

Example 4

The composition (weight percentage) of the formulated high-efficiency functional composite is 60% of tourmaline ultrafine powder, and 35% of crystalline infrared material ultrafine powder (including AL ₂ 0 ₃ 20%, content > 90%, MgO 15%, content > 90) %; ), mediated enhancer 0, 5% (for synthesizing n-citric acid vanillamide, 70%), embedding agent 4.5% (including paraffin oil 1%, rosin 1%, methyl cellulose 2) .5%). The average particle size of the tourmaline ultrafine powder is 125 nm, and the ultrafine particle size of the crystalline infrared material is 500 nm on average.

Among the above ingredients, tourmaline ultrafine powder is purchased from the market for high quality tourmaline ore, which is subjected to ordinary pulverization, followed by high speed ball milling and subsequent heat treatment. The high-speed ball milling time is 80 hours, the heat treatment temperature is 950 ° C, and the holding time is 2 hours. The crystal infrared material is purchased from the market through ordinary pulverized powder raw materials, subjected to high speed ball milling, and then heat treated. The high-speed ball milling time is 56 hours, the heat treatment temperature is 850 ° C, and the holding time is 2 hours.

The above ingredients are put into a V-type mixing mixer, mixed and stirred, and fully mixed and hooked, placed in a sealed constant temperature drying oven, and subjected to heating treatment, and the heating temperature is 15 (TC, holding time is 1 day. Become a high-efficiency composite functional powder material.

According to the weight percentage, 50% by weight of the powder material of the above-mentioned processed 髙 therapeutic functional composite, 50% by weight of soft solid matrix material (liquid resin), placed in the homogenizer, thoroughly stirred and mixed, and then vacuum pump Into the circle The film mold is heated and solidified (curing temperature is 180 °C), which becomes a high-effect functional material soft film, which is used for the treatment of special sensitive acupoints such as milk in the human body, to recover diseases and improve the quality of life.

Example 5

The composition (weight percentage) of the formulated high-efficiency functional composite is 40% of tourmaline ultrafine powder, 30% of crystalline infrared material ultrafine powder (AL ₂ 0 ₃ 30%, content > 90%), and 28% of intensive enhancer ( For the synthesis of n-antimonic acid vanillamide, 70%), embedding agent 2% (including paraffin oil 1%, rosin 1%), wherein the tourmaline ultrafine powder has an average particle size of 120 nm, AL ₂ 0 ₃ micropowder average The particle size is 1 micron.

Among the above ingredients, tourmaline ultrafine powder is a tourmaline ore originally purchased from the market, which is firstly pulverized and then put into a high-speed ball mill ball mill, followed by heat treatment. The high-speed ball milling time is 80 hours, the heat treatment temperature is 950 Ό, and the holding time is 2 hours. AL ₂ 0 ₃ is a powder purchased from the market. The powder has an average particle size of about 1 micrometer and is heat-treated at a heat treatment temperature of 800 ° C for 2 hours.

The above processed powder, medium-intensifying agent and embedding agent are put into a V-type mixing mixer, mixed and stirred, and thoroughly mixed, and placed in a sealed constant temperature drying oven for heating treatment and heating. The temperature is 150 Ό and the holding time is 2 days. It becomes a high-efficiency composite functional powder material.

According to the weight percentage, 50 parts by weight of the above-mentioned processed high-efficiency functional composite powder material, and 50% by weight of soft solid matrix material (liquid resin), placed in a homogenizer, thoroughly stirred and mixed, and then vacuum pump Pumped into a circular die, heated and cured (curing temperature is 180 °C), it becomes a super-soft functional film for high-efficiency functional materials, which is used for treatment of special acupoints such as Yongquan acupoints in human foot, rehabilitation Disease and improve the quality of life.

Industrial applicability

The therapeutic effect functional composite of the present invention may be a powder material, a hard solid material or a soft solid material, and can be used for improving the quality of life of human health care and chronic disease rehabilitation treatment equipment and equipment, and beauty and body. It is used to treat students' brain fatigue, treat children with learning difficulties, control heroin dependence withdrawal symptoms, treat dizziness, treat stroke sequelae, treat constipation irritable bowel syndrome, treat hypertension, treat coronary heart disease, treat senile dementia, treat Chronic enteritis, treatment of chronic prostatitis, treatment of trigeminal neuralgia, treatment of general headache, treatment of stomach, duodenal ulcer, etc., and the effect is remarkable.

Claims

1. A high-efficiency functional composite material characterized by being compounded by the following weight percentages of raw materials: tourmaline ultrafine powder and/or crystalline infrared material ultrafine powder 66-96%

Mediated strengthening material 0.01-30%

The embedding agent is 1-5%.

2. The composite material according to claim 1, wherein the tourmaline is a silicate natural mineral having a permanent electrode selected from the group consisting of iron tourmaline, magnesium tourmaline, iron-magnesium tourmaline, and lithium electrical. One or more of stone and other tourmaline, particle size <5 microns; the crystalline infrared material is selected from one or more of oxide crystals such as AL ₂ 0 ₃ , Si0 ₂ , MgO, Ti0 _{2 ,} etc. The diameter of the <500 micrometer; the mediated strengthening material is a vanillamide-containing alkaloid, the chemical name is N-(4-hydroxy-3-methoxybenzyl)-8-methylindole-anti-6 - one or more of a dilamide and its homologous analog and derivative compound monomers, which may be natural or synthetic, including but not limited to vanillin citrate; the embedding agent is paraffin oil, rosin, nail Any one or a combination of two of the celluloses.

3. A method of manufacturing a high-efficiency functional composite according to claim 1 or claim 2, comprising the following process steps:

(1) A weight percentage ingredient consisting of the high-efficiency functional composite according to claim 1 or claim 2;

(2) heat treatment of tourmaline ultrafine powder and/or crystalline infrared material ultrafine powder separately, heat treatment temperature 300-1000 V, holding time 1-5 hours;

(3) Mix and mix all the ingredients into the mixer to make them fully mixed;

(4) The mixed and well-mixed raw materials are placed in a sealed constant temperature drying oven for heating treatment. The heating temperature is 60-200 V, and the holding time is 1-3 days, which becomes the powder material of the high-efficiency functional composite material.

4. A method of manufacturing a high-efficiency composite material according to claim 1 or claim 2, further comprising the following process steps -

(5) using 20-60% by weight of the high-effect functional composite powder material, 40-80% by weight of the soft solid matrix material for the soft solid material formulation of the high-efficiency functional composite;

(6) The mixing and processing of the above ingredients according to the characteristics of the soft solid matrix material, that is, the soft solid material of the high-efficiency functional composite material.

5. A method of making a high-potency composite according to claim 4, wherein the soft solid matrix material is one or more of natural or synthetic rubber powder or other soft solid matrix material.

6. The method of manufacturing a high-efficiency composite material according to claim 1 or claim 2, further comprising the following process steps: (5) 'In the powder material of the high-efficiency functional composite powder material, 1-5 wt% of the binder relative to the powder material of the high-efficiency functional composite powder material is added, and then mixed well by adding the mixer. Uniform

(6) 'The above mixture is placed in a mold with a certain shape, pressed on a press, and the pressure is 12-30 Mpa, which is press-formed into a hard solid material of a high-efficiency functional composite.

The method for producing a high-efficiency composite material according to claim 6, wherein the binder is any one of linseed oil, castor oil, stearic acid, polyvinyl chloride, rosin, or a combination of any two .

8. Use of a high efficacy functional composite according to claim 1 or claim 2, which is useful in the field of human health, treatment and rehabilitation.

9. The use of the therapeutic effect functional composite according to claim 8, characterized in that it is treated at a sensitive point (acupoint) on the surface of the human body, and is effective for treating various non-infectious, non-nutritional chronic diseases by internal disease treatment. Disease and improve the quality of life.

10. The use of a high-efficiency functional composite according to claim 8 or claim 9, characterized in that it is made into various passive medical devices and instruments and other medical supplies, textiles, daily necessities, etc., instead of acupuncture, medical treatment and Active devices rehabilitate and treat diseases and improve quality of life.