WO2007117693A8 - Associations de protéines de régulation et de régions de régulation associées à une biosynthèse d'alcaloïdes - Google Patents

Associations de protéines de régulation et de régions de régulation associées à une biosynthèse d'alcaloïdes

Info

Publication number
WO2007117693A8
WO2007117693A8 PCT/US2007/008859 US2007008859W WO2007117693A8 WO 2007117693 A8 WO2007117693 A8 WO 2007117693A8 US 2007008859 W US2007008859 W US 2007008859W WO 2007117693 A8 WO2007117693 A8 WO 2007117693A8
Authority
WO
WIPO (PCT)
Prior art keywords
regulatory
alkaloid biosynthesis
associations related
protein
region associations
Prior art date
Application number
PCT/US2007/008859
Other languages
English (en)
Other versions
WO2007117693A2 (fr
Inventor
Nestor Apuya
Joon-Hyun Park
Steven Craig Bobzin
Original Assignee
Ceres Inc
Nestor Apuya
Joon-Hyun Park
Steven Craig Bobzin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceres Inc, Nestor Apuya, Joon-Hyun Park, Steven Craig Bobzin filed Critical Ceres Inc
Priority to US12/296,390 priority Critical patent/US20090222957A1/en
Publication of WO2007117693A2 publication Critical patent/WO2007117693A2/fr
Publication of WO2007117693A8 publication Critical patent/WO2007117693A8/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217—Gene switch
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PCT/US2007/008859 2006-04-07 2007-04-06 Associations de protéines de régulation et de régions de régulation associées à une biosynthèse d'alcaloïdes WO2007117693A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/296,390 US20090222957A1 (en) 2006-04-07 2007-04-06 Regulatory protein-regulatory region associations related to alkaloid biosynthesis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79048906P 2006-04-07 2006-04-07
US60/790,489 2006-04-07

Publications (2)

Publication Number Publication Date
WO2007117693A2 WO2007117693A2 (fr) 2007-10-18
WO2007117693A8 true WO2007117693A8 (fr) 2007-12-27

Family

ID=38581690

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/008859 WO2007117693A2 (fr) 2006-04-07 2007-04-06 Associations de protéines de régulation et de régions de régulation associées à une biosynthèse d'alcaloïdes

Country Status (2)

Country Link
US (1) US20090222957A1 (fr)
WO (1) WO2007117693A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2666860B1 (fr) 2007-12-05 2018-09-19 Toyota Jidosha Kabushiki Kaisha Gènes qui augmentent l'huile végétale et leur procédé d'utilisation
EP2230309B1 (fr) 2007-12-05 2016-03-09 Toyota Jidosha Kabushiki Kaisha Gène capable d'augmenter la production d'huile et de graisse dans une plante, et utilisation correspondante
JP5299886B2 (ja) 2008-03-04 2013-09-25 トヨタ自動車株式会社 植物の油脂を増産させる遺伝子及びその利用方法
US20120102599A1 (en) * 2009-04-29 2012-04-26 Crop Functional Genomics Center Plants Having Enhanced Yield-Related Traits and a Method for Making the Same
AU2014200653B2 (en) * 2009-06-04 2015-07-09 Toyota Jidosha Kabushiki Kaisha Gene for increasing plant weight and method for using the same
JP5519192B2 (ja) 2009-06-04 2014-06-11 トヨタ自動車株式会社 種子のタンパク質含量を増産させる遺伝子及びその利用方法
JP5718554B2 (ja) 2009-06-04 2015-05-13 トヨタ自動車株式会社 植物の植物重量を増産させる遺伝子及びその利用方法
JP5847991B2 (ja) 2009-06-04 2016-01-27 トヨタ自動車株式会社 種子における物質生産性を向上させる遺伝子及びその利用方法
BR112012027504B1 (pt) 2010-04-28 2022-05-24 Evogene Ltd Método de aumento de produção, biomassa, taxa de crescimento, e/ou tolerância ao estresse abiótico de uma planta, e, construção de ácidos nucleicos
US9617558B2 (en) * 2012-05-24 2017-04-11 Wiconsin Alumni Research Foundation Extending juvenility in grasses
US10370672B2 (en) 2014-02-18 2019-08-06 Vib Xvzw Means and methods for regulating secondary metabolite production in plants
EP3166965B1 (fr) 2014-07-10 2020-09-09 Benson Hill, Inc. L'invention concerne des compositions et des méthodes pour augmenter la croissance et le rendement de plantes
CN117599054B (zh) * 2024-01-24 2024-03-29 成都第一制药有限公司 一种治疗假性近视的药物组合物及其用途

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US583609A (en) * 1897-06-01 Alfred p
US505689A (en) * 1893-09-26 Cloth-cytting
US518075A (en) * 1894-04-10 Dolph
US583691A (en) * 1897-06-01 Bicycle-support
US544771A (en) * 1895-08-20 Heel compressing and loading machine
US612891A (en) * 1898-10-25 Rail-joint
US558869A (en) * 1896-04-21 Trolley for electric-railway cars
US757544A (en) * 1903-12-19 1904-04-19 Joseph Dobrodenka Extension-table.
US4936904A (en) * 1980-05-12 1990-06-26 Carlson Glenn R Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants
US5380831A (en) * 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4654465A (en) * 1985-07-18 1987-03-31 Agracetus Genic male-sterile maize
US5188958A (en) * 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
JPS62291904A (ja) * 1986-06-12 1987-12-18 Namiki Precision Jewel Co Ltd 永久磁石の製造方法
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4801540A (en) * 1986-10-17 1989-01-31 Calgene, Inc. PG gene and its use in plants
US4727219A (en) * 1986-11-28 1988-02-23 Agracetus Genic male-sterile maize using a linked marker gene
US4987071A (en) * 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5254678A (en) * 1987-12-15 1993-10-19 Gene Shears Pty. Limited Ribozymes
US5766847A (en) * 1988-10-11 1998-06-16 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Process for analyzing length polymorphisms in DNA regions
US5034323A (en) * 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5231020A (en) * 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5959177A (en) * 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US5859330A (en) * 1989-12-12 1999-01-12 Epitope, Inc. Regulated expression of heterologous genes in plants and transgenic fruit with a modified ripening phenotype
US5484956A (en) * 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
US6946587B1 (en) * 1990-01-22 2005-09-20 Dekalb Genetics Corporation Method for preparing fertile transgenic corn plants
US5204253A (en) * 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5432068A (en) * 1990-06-12 1995-07-11 Pioneer Hi-Bred International, Inc. Control of male fertility using externally inducible promoter sequences
US6207881B1 (en) * 1990-09-10 2001-03-27 The United States Of America As Represented By The Department Of Agriculture Control of fruit ripening through genetic control of ACC synthase synthesis
SE467358B (sv) * 1990-12-21 1992-07-06 Amylogene Hb Genteknisk foeraendring av potatis foer bildning av staerkelse av amylopektintyp
US5612487A (en) * 1991-08-26 1997-03-18 Edible Vaccines, Inc. Anti-viral vaccines expressed in plants
US5591616A (en) * 1992-07-07 1997-01-07 Japan Tobacco, Inc. Method for transforming monocotyledons
US5280831A (en) * 1992-12-24 1994-01-25 Conklin Jr Dennis R Information panels for use on conveyor systems and method of use
US6118047A (en) * 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US5410270A (en) * 1994-02-14 1995-04-25 Motorola, Inc. Differential amplifier circuit having offset cancellation and method therefor
US5777079A (en) * 1994-11-10 1998-07-07 The Regents Of The University Of California Modified green fluorescent proteins
CN1183802A (zh) * 1994-12-30 1998-06-03 行星生物技术有限公司 在植物中生产含有保护性蛋白质的免疫球蛋白的方法和应用
JPH11500922A (ja) * 1995-03-03 1999-01-26 ノバルティス・アクチエンゲゼルシャフト 化学リガンドの存在下での受容体媒介トランス活性化による植物における遺伝子発現の制御
CA2221411A1 (fr) * 1995-05-19 1996-11-21 Phytera, Inc. Manipulation de cultures de cellules et de tissus vegetaux
US5925806A (en) * 1995-06-06 1999-07-20 Mcbride; Kevin E. Controlled expression of transgenic constructs in plant plastids
WO1997014812A2 (fr) * 1995-10-16 1997-04-24 Chiron Corporation Procede de criblage pour la recherche de facteurs qui modulent l'expression genique
US5958745A (en) * 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US5824779A (en) * 1996-04-26 1998-10-20 Wisconsin Alumni Research Foundation Phytase-protein-pigmenting concentrate derived from green plant juice
US5900525A (en) * 1996-04-26 1999-05-04 Wisconsin Alumni Research Foundation Animal feed compositions containing phytase derived from transgenic alfalfa and methods of use thereof
DE19617687C2 (de) * 1996-05-03 2000-11-16 Suedzucker Ag Verfahren zur Herstellung transgener, Inulin erzeugender Pflanzen
US6846669B1 (en) * 1996-08-20 2005-01-25 The Regents Of The University Of California Methods for improving seeds
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
EP0977836A4 (fr) * 1997-02-21 2002-10-16 Univ California Genes de type "cotyledon1 feuillu" et leurs utilisations
GB9710475D0 (en) * 1997-05-21 1997-07-16 Zeneca Ltd Gene silencing
US20040203109A1 (en) * 1997-06-06 2004-10-14 Incyte Corporation Human regulatory proteins
US6452067B1 (en) * 1997-09-19 2002-09-17 Dna Plant Technology Corporation Methods to assay for post-transcriptional suppression of gene expression
AUPP249298A0 (en) * 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
US6010907A (en) * 1998-05-12 2000-01-04 Kimeragen, Inc. Eukaryotic use of non-chimeric mutational vectors
US6087558A (en) * 1998-07-22 2000-07-11 Prodigene, Inc. Commercial production of proteases in plants
US7858848B2 (en) * 1999-11-17 2010-12-28 Mendel Biotechnology Inc. Transcription factors for increasing yield
US7511190B2 (en) * 1999-11-17 2009-03-31 Mendel Biotechnology, Inc. Polynucleotides and polypeptides in plants
US7345217B2 (en) * 1998-09-22 2008-03-18 Mendel Biotechnology, Inc. Polynucleotides and polypeptides in plants
US20030061637A1 (en) * 1999-03-23 2003-03-27 Cai-Zhong Jiang Polynucleotides for root trait alteration
US20100293669A2 (en) * 1999-05-06 2010-11-18 Jingdong Liu Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
AU4940700A (en) * 1999-05-28 2000-12-18 Sangamo Biosciences, Inc. Gene switches
DE60042763D1 (de) * 1999-07-01 2009-09-24 Calgene Llc Kontrolle der Genexpression in eukaryotischen Zellen
US6423885B1 (en) * 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US6294717B1 (en) * 1999-10-15 2001-09-25 Ricetec, Ag Inbred rice lines A0044 and B0044
GB9925459D0 (en) * 1999-10-27 1999-12-29 Plant Bioscience Ltd Gene silencing
US7151201B2 (en) * 2000-01-21 2006-12-19 The Scripps Research Institute Methods and compositions to modulate expression in plants
US20020023281A1 (en) * 2000-01-27 2002-02-21 Jorn Gorlach Expressed sequences of arabidopsis thaliana
US20070016976A1 (en) * 2000-06-23 2007-01-18 Fumiaki Katagiri Plant genes involved in defense against pathogens
EP1313867A2 (fr) * 2000-08-24 2003-05-28 The Scripps Research Institute Sequences nucleotidiques de plantes a stress regule, plantes transgeniques contenant ces sequences, et methodes d'utilisation stress-regulated nucleotide sequences of plants, transgenic plants containing same, and methods of use
JP4028956B2 (ja) * 2000-10-11 2008-01-09 独立行政法人農業生物資源研究所 イネ貯蔵タンパク質の発現を制御するｂＺＩＰ型転写因子
US7276370B2 (en) * 2000-10-24 2007-10-02 Donald Danforth Plant Science Center Rf2a and rf2b transcription factors
AU2001297906B2 (en) * 2000-10-31 2007-07-19 Commonwealth Scientific And Industrial Research Organisation Method and means for producing barley yellow dwarf virus resistant cereal plants
US7279317B2 (en) * 2001-01-12 2007-10-09 California Institute Of Technology Modulation of COP9 signalsome isopeptidase activity
WO2003000038A2 (fr) * 2001-06-22 2003-01-03 The Regents Of The University Of California Compositions et procedes de modulation du developpement de plantes
CN100400661C (zh) * 2001-10-25 2008-07-09 孟山都技术有限公司 芳族甲基转移酶及其应用
JP2003144175A (ja) * 2001-11-19 2003-05-20 Inst Of Physical & Chemical Res 環境ストレス応答性プロモーター
US20050108791A1 (en) * 2001-12-04 2005-05-19 Edgerton Michael D. Transgenic plants with improved phenotypes
US7176027B2 (en) * 2001-12-20 2007-02-13 Pioneer Hi-Bred International, Inc. Genes and regulatory DNA sequences associated with stress-related gene expression in plants and methods of using the same
US6924075B2 (en) * 2002-02-22 2005-08-02 Xeikon International N.V. Dry toner composition
CN1643147B (zh) * 2002-03-14 2010-04-14 联邦科学和工业研究组织 监测和调节基因沉默的方法和工具
US7576262B2 (en) * 2002-03-14 2009-08-18 Commonwealth Scientific And Industrial Research Organization Modified gene-silencing RNA and uses thereof
US20040053876A1 (en) * 2002-03-26 2004-03-18 The Regents Of The University Of Michigan siRNAs and uses therof
US20060194959A1 (en) * 2002-07-15 2006-08-31 Nickolai Alexandrov Sequence-determined DNA fragments encoding SRF-type transcription factors
US20040078852A1 (en) * 2002-08-02 2004-04-22 Thomashow Michael F. Transcription factors to improve plant stress tolerance
US7173121B2 (en) * 2003-10-14 2007-02-06 Ceres, Inc Promoter, promoter control elements, and combinations, and uses thereof
US7378571B2 (en) * 2004-09-23 2008-05-27 Ceres, Inc. Promoter, promoter control elements, and combinations, and uses thereof
US20060021083A1 (en) * 2004-04-01 2006-01-26 Zhihong Cook Promoter, promoter control elements, and combinations, and uses thereof
US7569389B2 (en) * 2004-09-30 2009-08-04 Ceres, Inc. Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics
US20060143729A1 (en) * 2004-06-30 2006-06-29 Ceres, Inc. Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics
WO2005038040A2 (fr) * 2003-10-14 2005-04-28 Ceres, Inc. Procedes et compositions permettant de modifier les phenotypes des semences
US20060015970A1 (en) * 2003-12-12 2006-01-19 Cers, Inc. Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics
US20070006335A1 (en) * 2004-02-13 2007-01-04 Zhihong Cook Promoter, promoter control elements, and combinations, and uses thereof
WO2006005023A2 (fr) * 2004-06-30 2006-01-12 Ceres Inc. Promoteur, elements et combinaisons de controle de promoteur, et leurs utilisations
WO2006023766A2 (fr) * 2004-08-20 2006-03-02 Ceres Inc. Polynucleotides, polypeptides de p450 et leurs utilisations
US7429692B2 (en) * 2004-10-14 2008-09-30 Ceres, Inc. Sucrose synthase 3 promoter from rice and uses thereof
CA2598436A1 (fr) * 2005-02-22 2006-08-31 Ceres, Inc. Alcaloides vegetaux de modulation

Also Published As

Publication number Publication date
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WO2007117693A2 (fr) 2007-10-18

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