WO2007116891A1 - Dispositif d'injection de substances chimiques - Google Patents

Dispositif d'injection de substances chimiques Download PDF

Info

Publication number
WO2007116891A1
WO2007116891A1 PCT/JP2007/057495 JP2007057495W WO2007116891A1 WO 2007116891 A1 WO2007116891 A1 WO 2007116891A1 JP 2007057495 W JP2007057495 W JP 2007057495W WO 2007116891 A1 WO2007116891 A1 WO 2007116891A1
Authority
WO
WIPO (PCT)
Prior art keywords
injection
graph
chemical
input
rate
Prior art date
Application number
PCT/JP2007/057495
Other languages
English (en)
Japanese (ja)
Inventor
Shigeru Nemoto
Original Assignee
Nemoto Kyorindo Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nemoto Kyorindo Co., Ltd. filed Critical Nemoto Kyorindo Co., Ltd.
Priority to JP2008509857A priority Critical patent/JP5063593B2/ja
Publication of WO2007116891A1 publication Critical patent/WO2007116891A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3561—Range local, e.g. within room or hospital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir

Definitions

  • the present invention relates to a chemical liquid injector that is used together with a medical fluoroscopic imaging apparatus and injects a chemical liquid into a subject who captures a fluoroscopic image.
  • Emission Tomography equipment, ultrasonic diagnostic equipment, CT angiography equipment, MRA (MR Angio) equipment, etc. are known.
  • a subject is infused with a medical solution such as a contrast medium, a radioactive substance, or physiological saline for obtaining a good fluoroscopic image or for other purposes. Is called.
  • a chemical solution injection device for injecting these chemical solutions has been put into practical use. For example, when injecting contrast medium, the contrast medium injection is divided into multiple phases so that the optimal CT value can be obtained within the scanning period of the CT device, and the injection rate is changed for each phase. Attempts have been made to change the contrast agent concentration.
  • Patent Document 1 Japanese Unexamined Patent Application Publication No. 2004-113475
  • Patent Document 2 discloses a touch panel in which the horizontal axis represents time and the vertical axis represents the injection speed, and the injection graph can be freely displayed on the display using a pen input device.
  • a method is described in which a change in contrast agent injection rate with time (hereinafter referred to as an injection protocol) is determined by drawing a curve.
  • Patent Document 2 also describes that when a plurality of passing points are input, a free curve that sequentially passes through the plurality of points is generated.
  • Patent Document 1 JP 2004-113475 A
  • Patent Document 2 Japanese Patent Application Laid-Open No. 2004-298549
  • the present invention was made to further improve the prior art, and by displaying a feasible injection protocol on the display, chemical injection that enables accurate injection according to the displayed injection rate graph
  • An object is to provide an apparatus.
  • the present invention relates to the following matters.
  • a display means for displaying an injection graph indicating the injection speed of the chemical solution on the vertical axis and an injection time on the horizontal axis; an input means for inputting the injection graph of the chemical liquid;
  • a curve correction means for analyzing the input injection graph and correcting a curve on the graph in which the injection speed exceeds the allowable change rate, including before and after the range, so that the range is less than the allowable value;
  • the allowable change rate of the injection rate is set by a radius of curvature on a graph. 2.
  • the display means displays a grid screen that also functions as a scale of an injection graph, and the input of the injection graph is performed by designating a point on the grid screen, and the input injection graph is a line 4.
  • the chemical injection device according to any one of 1 to 3 above, which is given as:
  • the drug solution injection device according to any one of the above 1 to 4, further comprising display switching means for an input injection graph and a curve-corrected injection graph.
  • the injection device of the present invention it is possible to provide a chemical solution injection device capable of performing accurate injection according to the displayed injection rate graph by displaying an actually possible injection protocol on the display. Therefore, a contrast medium with high injection accuracy can be used effectively, and the load on the motor can be reduced.
  • FIG. 1 is a diagram showing an example of a fluoroscopic imaging system to which the present invention is applied.
  • FIG. 2 is a perspective view showing an appearance of an example of an injection device.
  • FIG. 3 is a perspective view showing a state where a chemical syringe is attached to the injection head of the injection apparatus.
  • FIG. 4 is a block diagram showing an example of the configuration of the present invention.
  • FIG. 5 is a screen for accepting input, and shows a state where a grid screen is displayed with the injection speed being the vertical axis and the injection time being the horizontal axis.
  • FIG. 6 A diagram showing a screen displaying a state in which points are input on a grid screen and connected by a straight line.
  • FIG. 7 is a diagram showing an injection graph that has been subjected to curve correction according to an example of the present invention.
  • FIG. 8 is a diagram showing an example of curve correction with a loose approximation to a straight line connecting input points.
  • FIG. 10 A diagram showing an example of a conventional injection protocol.
  • FIG. 11 A diagram showing an example of a conventional injection protocol.
  • the fluoroscopic imaging system 1000 in which the chemical injection device of the present invention is used has a chemical injection device 100 and a CT scanner 300 that is a fluoroscopic imaging device.
  • the scanner 300 is connected by wire.
  • the CT scanner 300 has a scanner main body 301 and a control queue 302.
  • the chemical injection device 100 has an injection head 110 mounted on the upper part of an arm 112 connected to a stand 111, and a separate injection control unit 101 connected to a cable 102. Connected by.
  • the injection control unit 101 includes a main operation panel 103, a display unit 104, a node unit 107 connected by a cable 108, and the like.
  • the injection head 110 has two concave portions 114 formed on the upper surface of the head main body 113 as a syringe holding mechanism, and the two syringes 200C and 200P are formed in the concave portion 114.
  • the syringes 200C and P have a cylinder 210 and a piston 220.
  • the syringe 200C is filled with a contrast medium for CT as a chemical solution
  • the syringe 200P is filled with physiological saline.
  • the tips of the two syringes attached to the head body 113 are connected by a connecting tube 230.
  • the piston 220 of each syringe is pushed by the piston drive mechanism 130 that can move independently, so that it is possible to inject contrast medium, inject physiological saline, and simultaneously inject both of them.
  • FIG. 4 is a block diagram showing the configuration of the chemical liquid injector according to the present invention.
  • 5 to 9 show screens of the display unit 104 of the main operation panel.
  • the configuration of the present invention will be explained using FIG. 4 and FIGS. Light up.
  • the means or mechanism described with reference to FIG. 4 exists as at least a part of the configuration described with reference to FIGS. In addition, even if it exists as nodware, it also includes what exists as a logical configuration.
  • the display unit 104 of the main panel serves as both the display unit 120 and the input unit 121.
  • the injection rate is indicated on the vertical axis as shown in FIG.
  • the infusion time is displayed on the horizontal grid.
  • the display unit is preferably a touch panel, and an injection rate at a specific elapsed time can be input by, for example, pen input.
  • the time lapse of the injection rate is designated and input in points.
  • the points are connected in a straight line as shown in Fig. 6.
  • Data is sent from the display means 120 to the curve correction means 123, and the curve correction means 123 performs an operation for correcting the injection graph indicated by the broken line into a curve.
  • the injection device receives the click of the “Curve Correction” icon or the switch is pressed by the operator, the screen is switched to display an injection graph with a corrected curve as shown in FIG.
  • the calculation function in the curve correction means analyzes the input injection graph so that the rate of change of the injection rate is less than the allowable rate of change.
  • the corners are rounded.
  • the degree of “rounding” is rounded at least within a range that the motor can follow, and is preferably adjusted in consideration of the load on the motor and power consumption.
  • the curve correction is performed so that the absolute value of the injection acceleration obtained by time differentiation of the injection speed is equal to or less than a predetermined value determined in consideration of the motor performance. That's right. It is also preferable that the curve correction is performed so that the absolute value of the injection acceleration is continuous, or if the injection acceleration is discontinuous, the discontinuous value is equal to or less than a predetermined value. Particularly preferably, the absolute value of the injection acceleration is continuous. It is extremely preferable that the curve correction is performed so that the absolute value of the injection acceleration is continuous and the absolute value of the injection acceleration is not more than a predetermined value.
  • curve correction may be performed so that the maximum curvature on the injection graph is equal to or less than a predetermined value that is determined in consideration of the motor capacity.
  • the correction conversion from the polygonal line to the curve is preferably performed by spline curve interpolation.
  • interpolation is performed so that the vertex of the polygonal line does not pass.
  • the polygonal line connecting the input points is simply spline curve interpolated as shown in FIG. 8, it may be far away from the input point as shown in FIG.
  • a virtual point Vp may be set in the vicinity of the input point, and a spline curve including the virtual point Vp may be obtained.
  • the rate of change of the injection rate exceeds the allowable rate of change, so it is necessary to separate the rate so that the rate of change of the injection rate is below the allowable rate of change. .
  • the apparatus of the present invention may further have additional functions.
  • display switching means between an input injection graph displayed as a broken line and a curve-corrected injection graph. It is also preferable to further include means for changing the input point. For example, these points are implemented by dragging and changing already input points on the display screen.
  • an injection graph may be input with a curve.
  • the curve correction is performed so that the calculation function in the curve correction means analyzes the input injection graph as in Embodiment 1 so that the change rate of the injection rate is less than the allowable change rate.
  • a sharp angle Rounding is performed.
  • the degree of rounding is, specifically, the curve correction is performed so that the absolute value of the injection acceleration obtained by time differentiation of the injection speed is not more than a predetermined value. Is preferred. It is extremely preferable that the curve correction is performed so that the absolute value of the injection acceleration is continuous and the absolute value of the injection acceleration is not more than a predetermined value.
  • curve correction may be performed so that the maximum curvature on the injection graph is less than or equal to a predetermined value that is determined taking into account the power of the motor.
  • contrast medium injection for CT has been described as an example.
  • the present invention can also be applied to contrast medium injection for MRI and injection to other chemicals.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

On décrit un dispositif d'injection de substances chimiques dans lequel un protocole d'injection pouvant être effectivement mis en œuvre est affiché sur un écran, l'injection pouvant être accomplie exactement selon un graphe de taux d'injection affiché. Le dispositif d'injection de substances chimiques (100) comprend: un moyen d'injection de substances chimiques (135); un moyen (120) pour afficher un graphe d'injection indiquant le taux d'injection de substances chimiques sur l'ordonnée et le temps d'injection sur l'abscisse; un moyen (121) pour saisir le graphe d'injection de substances chimiques; et un moyen (123) pour soumettre à une correction de courbe une plage du graphe où le taux d'injection dépasse un taux de variation admissible et des parties précédant ou suivant immédiatement la plage, par analyse d'un graphe d'injection saisi, de sorte que la plage atteigne une valeur admissible.
PCT/JP2007/057495 2006-04-06 2007-04-03 Dispositif d'injection de substances chimiques WO2007116891A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008509857A JP5063593B2 (ja) 2006-04-06 2007-04-03 薬液注入装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006-105580 2006-04-06
JP2006105580 2006-04-06

Publications (1)

Publication Number Publication Date
WO2007116891A1 true WO2007116891A1 (fr) 2007-10-18

Family

ID=38581181

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/057495 WO2007116891A1 (fr) 2006-04-06 2007-04-03 Dispositif d'injection de substances chimiques

Country Status (2)

Country Link
JP (1) JP5063593B2 (fr)
WO (1) WO2007116891A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11478581B2 (en) 2017-08-31 2022-10-25 Bayer Healthcare Llc Fluid injector system volume compensation system and method
US11598664B2 (en) 2017-08-31 2023-03-07 Bayer Healthcare Llc Injector pressure calibration system and method
US11672902B2 (en) 2016-03-03 2023-06-13 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
US11779702B2 (en) 2017-08-31 2023-10-10 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
US11786652B2 (en) 2017-08-31 2023-10-17 Bayer Healthcare Llc System and method for drive member position and fluid injector system mechanical calibration
US11826553B2 (en) 2017-08-31 2023-11-28 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04501627A (ja) * 1989-08-31 1992-03-19 デューク ユニバーシティ 開ループプロセスをモデルに基づいて制御する方法及び装置
JP2004298549A (ja) * 2003-04-01 2004-10-28 Nemoto Kyorindo:Kk 薬液注入装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7308300B2 (en) * 2001-05-30 2007-12-11 Acist Medical Systems, Inc. Medical injection system
EP1681069A4 (fr) * 2003-10-29 2007-09-12 Nemoto Kyorindo Co Ltd Dispositif de perfusion de liquide medicinal

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04501627A (ja) * 1989-08-31 1992-03-19 デューク ユニバーシティ 開ループプロセスをモデルに基づいて制御する方法及び装置
JP2004298549A (ja) * 2003-04-01 2004-10-28 Nemoto Kyorindo:Kk 薬液注入装置

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11672902B2 (en) 2016-03-03 2023-06-13 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
US11478581B2 (en) 2017-08-31 2022-10-25 Bayer Healthcare Llc Fluid injector system volume compensation system and method
US11598664B2 (en) 2017-08-31 2023-03-07 Bayer Healthcare Llc Injector pressure calibration system and method
US11779702B2 (en) 2017-08-31 2023-10-10 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
US11786652B2 (en) 2017-08-31 2023-10-17 Bayer Healthcare Llc System and method for drive member position and fluid injector system mechanical calibration
US11826553B2 (en) 2017-08-31 2023-11-28 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance

Also Published As

Publication number Publication date
JPWO2007116891A1 (ja) 2009-08-20
JP5063593B2 (ja) 2012-10-31

Similar Documents

Publication Publication Date Title
JP4490642B2 (ja) 薬液注入装置
EP1402910B1 (fr) Injecteur de liquide pour injecter un médium de contraste à un débit variable dans un patient
JP5203971B2 (ja) 薬液注入装置
EP2985047B1 (fr) Dispositif et système d'injection de produit chimique
US9031639B2 (en) Chemical liquid injector and CT apparatus
JP5063593B2 (ja) 薬液注入装置
JP5117376B2 (ja) 薬液注入装置
US20060184122A1 (en) Medicine infuser for displaying image of entered infusion condition
EP2686040B1 (fr) Dispositif et procédé pour déterminer des paramètres d'injection de milieu de contraste par rapport à l'intensité d'un signal de commande pendant une angiographie par résonance magnétique
US20170246378A1 (en) Medical fluid injector device
JP2011147796A (ja) 注入処置の１又は複数フェーズのパラメータを決定する装置、システム及び方法
US8926555B2 (en) Power injector with flow rate assessment
US20110218434A1 (en) Workflow Driven User Interface for a Power Injection Systems
WO2007114447A1 (fr) Dispositif d'injection de liquide médical
JP5005678B2 (ja) 薬液注入装置
JP2005198808A (ja) 透視撮像システム
JP5770762B2 (ja) 薬液注入装置
JP5265520B2 (ja) 薬液注入装置および該薬液注入装置の制御方法
WO2007097422A1 (fr) Unite d'injection de liquide
WO2008072636A1 (fr) Appareil de dosage chimique
JP2003290348A (ja) Ｍｒｉ対応注入装置
JP5329156B2 (ja) 薬液注入装置及びそれを備えたシステム
JP4233854B2 (ja) 薬液注入装置
CN117899291A (zh) 气体微球或造影剂用微量泵的控制方法、控制系统及应用

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07740931

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2008509857

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07740931

Country of ref document: EP

Kind code of ref document: A1