WO2007115691A1 - Anti-parasitic and/or disinfectant and/or insect-repellent and/or detergent composition - Google Patents

Anti-parasitic and/or disinfectant and/or insect-repellent and/or detergent composition Download PDF

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Publication number
WO2007115691A1
WO2007115691A1 PCT/EP2007/002779 EP2007002779W WO2007115691A1 WO 2007115691 A1 WO2007115691 A1 WO 2007115691A1 EP 2007002779 W EP2007002779 W EP 2007002779W WO 2007115691 A1 WO2007115691 A1 WO 2007115691A1
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composition
present
parasitic
buildings
disinfectant
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PCT/EP2007/002779
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French (fr)
Inventor
Richard Alasri
Helene Charier
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Cid Lines N.V.
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Publication of WO2007115691A1 publication Critical patent/WO2007115691A1/en

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof

Definitions

  • TITLE Anti-parasitic and / or disinfecting and / or insecticidal and / or insect repellent and / or detergent composition.
  • the present invention relates to a pest control composition and / or disinfectant and / or insecticide and / or insect repellent and / or detergent.
  • the present invention relates to an anti-parasitic and / or disinfecting and / or insecticidal and / or insect repellent and / or detergent composition in order to destroy and / or inhibit unicellular organisms and / or arthropods for buildings, in particular soil, walls. and / or ceiling, in particular breeding, with or without animals.
  • Coccidiosis is an infection caused by unicellular organisms These organisms are part of the class of protozoa and are most commonly called coccidia. Oocysts, that is, coccidia before maturation, are eliminated in the feces of animals. They stay in the environment and eventually sporulate, that is, they mature, and may in turn infect other animals.
  • German patent document DE-10 222 455 describes, for example, the use of a combined ester with a phenol having an anti-parasitic effect.
  • this type of composition has some disadvantages, particularly in terms of their toxicity to animals, humans and the environment. It is particularly well known the toxicity of these compounds in contact with the skin and by ingestion and their ability to cause burns especially phenol and ammonia.
  • Another method to eliminate this type of organism Unicellular is to disinfect the environment with bleach, which also presents a toxicity for the user and the environment.
  • the object of the present invention is therefore to provide an anti-parasitic and / or disinfecting and / or insecticidal and / or insect repellent and / or detergent composition which overcomes the aforementioned drawbacks, and in particular with regard to the toxicity of the products used.
  • Another object of the present invention is to provide an anti-parasitic and / or disinfectant and / or insecticidal and / or insect repellent and / or detergent composition that can be used on floors, walls and / or ceilings of buildings, in particular breeding in the presence or absence of animals, without any toxicity to animals and / or the environment.
  • the present invention relates to a pest control and / or disinfectant and / or insecticidal and / or insective and / or detergent composition for destroying and / or inhibiting unicellular organisms and / or arthropods for buildings, in particular soil, paras and / or ceiling , especially breeding, with or without animals.
  • said composition contains at least one fatty acid.
  • One of the advantages of the present composition as described in the present application lies in the fact that it is devoid of any toxicity and can be used to disinfect all premises or livestock buildings even in the presence of animals.
  • composition as described in the present invention may further contain at least one surfactant.
  • surfactant also called surfactant is meant any compound that modifies the surface tension between two surfaces.
  • the surfactant compounds are amphiphilic molecules, i.e. have two parts of different polarities, one lipophilic, miscible in oil and apolar, the other hydrophilic, miscible in water and polar.
  • One of the functions of the surfactants according to the present invention is to allow the attachment of hydrophobic molecules, in particular fatty acids, in order to mix them with hydrophilic molecules, such as water thus improving contact with the parasites, and this fact, improving efficiency.
  • Fatty acids are carboxylic acids having a long hydrophobic chain that can be saturated or unsaturated.
  • the fatty acid is caprylic acid.
  • Caprylic acid also known as octanoic acid, is a linear-chain saturated fatty acid with eight carbon atoms. It is present naturally in coconut and breast milk, in the form of an oily liquid. Indeed, fatty acids are natural products that are often found in our diet.
  • the fatty acid is oleic acid.
  • Oleic acid is one of the most abundant of long chain fatty acids, and is in the form of a liquid (oil) which only solidifies at 40.degree .
  • composition as described in the present invention may further contain at least one biocide and / or cleaner.
  • the composition as described may contain simultaneously or individually caprylic acid and oleic acid.
  • the composition as it is described may further contain a diluent.
  • diluent any organic and / or aqueous solvent, which can be added to said composition without altering its anti-parasitic and / or disinfectant properties and / or insecticides and / or insect repellents and / or detergents.
  • diluent any organic and / or aqueous solvent, which can be added to said composition without altering its anti-parasitic and / or disinfectant properties and / or insecticides and / or insect repellents and / or detergents.
  • the table below shows the components of two different compositions 1 and 2 as described in the present invention, and the comparison of the results obtained by these compositions 1 and 2 and by the composition (A ) currently marketed and containing phenol.
  • compositions as described in the present invention have been tested in particular against Eimeria tenella oocysts according to the German DGV protocol. After the contact time, the action of the composition and the control product is neutralized by dilution. The amount of sporulated oocysts is counted. Each product has a value corresponding to its ability to reduce the amount of occyst is calculated from a starting population of 25,000 oocysts.
  • compositions as described in the present invention are quite similar to those obtained with the phenol-containing composition.
  • the action of the fatty acids is proven to be effective for the eradication of said oocysts and the inventors have furthermore demonstrated that the compositions containing fatty acids, in particular caprylic acid and oleic acid, are at least as effective as a phenol product.
  • Such a composition as described in the present invention is used as an anti-parasitic composition against unicellular organisms, especially protozoa and in particular oocysts.
  • Oocysts are protozoa of the sporozoal type. More particularly, such a composition, as described in the present invention is used as an anti-parasitic composition, especially against arthropods, such as red lice poultry houses.
  • said composition is used to prevent and / or control coccidiosis.
  • such a composition as described in the present invention can be used as an anti-parasitic composition for the treatment of surfaces including floors, walls and / or ceilings of livestock buildings such as the chicken coop and / or or the stables.
  • thermobell in order to eliminate this type of parasite that contaminate livestock buildings and especially poultry houses and / or stables, one of the most effective ways is to spray, thermobell or soak the surfaces of these buildings.
  • composition as described above can be used in pure state or diluted by ingestion and / or externally.
  • the compositions as described in the present invention allow a reduction of 90% of the lice by simple contact, under the harmful effect of conventional insecticides currently prohibited in the presence of animals in the laying hen farms, which This is not the case with the present composition.

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present invention relates to an anti-parasitic and/or disinfectant and/or insecticidal and/or insect-repellent and/or detergent composition in order to destroy and/or inhibit unicellular organisms and/or arthropods, for buildings, especially floors, walls and/or ceilings, in particular livestock buildings, in the presence or absence of animals. According to the invention, the composition as described in the present invention contains at least one fatty acid. The present invention also relates to the use of said composition as an anti-parasitic composition against unicellular organisms, especially protozoa, and in particular oocysts. In addition, the present invention relates to the use of such a composition as an anti-parasitic composition, especially against arthropods, and in particular against red mites in henhouses.

Description

TITRE : Composition anti-parasitaire et/ou désinfectante et/ou insecticide et/ou insectifuge et/ou détergente.TITLE: Anti-parasitic and / or disinfecting and / or insecticidal and / or insect repellent and / or detergent composition.
La présente invention concerne une composition antiparasitaire et/ou désinfectante et/ou insecticide et/ou insectifuge et/ou détergente.The present invention relates to a pest control composition and / or disinfectant and / or insecticide and / or insect repellent and / or detergent.
Particulièrement, la présente invention concerne une composition anti-parasitaire et/ou désinfectante et/ou insecticide et/ou insectifuge et/ou détergente afin de détruire et/ou inhiber des organismes unicellulaires et/ou des arthropodes pour les bâtiments, notamment sol, parois et/ou plafond, en particulier d'élevage, en présence ou non d'animaux.In particular, the present invention relates to an anti-parasitic and / or disinfecting and / or insecticidal and / or insect repellent and / or detergent composition in order to destroy and / or inhibit unicellular organisms and / or arthropods for buildings, in particular soil, walls. and / or ceiling, in particular breeding, with or without animals.
A ce jour, il existe peu de solutions diluées anti-parasitaires à appliquer sur les surfaces, notamment sur les sols et murs, des bâtiments d'élevage qui soient efficaces contre les spores de certaines maladies, et notamment contre les spores de coccidiose. La coccidiose est une infection provoquée par des organismes unicellulaires Ces organismes font partie de la classe des protozoaires et on les appelle le plus souvent de coccidies. Les oocystes, c'est-à-dire les coccidies avant maturation, sont éliminés dans les selles des animaux. Ils restent dans l'environnement et éventuellement sporulent, c'est-à-dire arrivent à maturation, et peuvent, à leur tour, infecter d'autres animaux.To date, there are few dilute anti-parasitic solutions to be applied to the surfaces, especially on the floors and walls, livestock buildings that are effective against the spores of certain diseases, including coccidiosis spores. Coccidiosis is an infection caused by unicellular organisms These organisms are part of the class of protozoa and are most commonly called coccidia. Oocysts, that is, coccidia before maturation, are eliminated in the feces of animals. They stay in the environment and eventually sporulate, that is, they mature, and may in turn infect other animals.
En général, les solutions utilisées aujourd'hui pour éliminer ce type d'organisme contiennent des composés tels que les phénols, le chloroforme et/ou l'ammoniaque. Le document allemand DE-10.222.455 décrit, par exemple, l'utilisation d'un ester combiné à un phénol ayant un effet anti- parasitaire.In general, the solutions used today to eliminate this type of organism contain compounds such as phenols, chloroform and / or ammonia. German patent document DE-10 222 455 describes, for example, the use of a combined ester with a phenol having an anti-parasitic effect.
Toutefois, ce type de composition présente quelques inconvénients, notamment au niveau de leur toxicité pour les animaux, l'homme et l'environnement. Il est notamment bien connu la toxicité de ces composés par contact avec la peau et par ingestion ainsi que leur capacité de provoquer des brûlures en particulier le phénol et l'ammoniaque.However, this type of composition has some disadvantages, particularly in terms of their toxicity to animals, humans and the environment. It is particularly well known the toxicity of these compounds in contact with the skin and by ingestion and their ability to cause burns especially phenol and ammonia.
Une autre méthode pour éliminer ce type d'organisme unicellulaire consiste à désinfecter l'environnement avec de l'eau de javel, ce qui présente également une toxicité pour l'utilisateur et l'environnement.Another method to eliminate this type of organism Unicellular is to disinfect the environment with bleach, which also presents a toxicity for the user and the environment.
Le but de la présente invention est donc de proposer une composition anti-parasitaire et/ou désinfectante et/ou insecticide et/ou insectifuge et/ou détergente qui pallie les inconvénients précités, et notamment au niveau de la toxicité des produits utilisés.The object of the present invention is therefore to provide an anti-parasitic and / or disinfecting and / or insecticidal and / or insect repellent and / or detergent composition which overcomes the aforementioned drawbacks, and in particular with regard to the toxicity of the products used.
Un autre but de la présente invention est de proposer une composition anti-parasitaire et/ou désinfectante et/ou insecticide et/ou insectifuge et/ou détergente pouvant être utilisée sur sols, les parois et/ou plafonds des bâtiments, en particulier d'élevage en présence ou en absence d'animaux, sans aucune toxicité pour les animaux et/ou pour l'environnement.Another object of the present invention is to provide an anti-parasitic and / or disinfectant and / or insecticidal and / or insect repellent and / or detergent composition that can be used on floors, walls and / or ceilings of buildings, in particular breeding in the presence or absence of animals, without any toxicity to animals and / or the environment.
D'autres buts et avantages de la présente invention apparaîtront au cours de la description qui va suivre qui n'est donnée qu'à titre indicatif et qui n'a pas pour but de la limiter. La présente invention concerne une composition antiparasitaire et/ou désinfectante et/ou insecticide et/ou insectifigue et/ou détergente afin de détruire et/ou inhiber des organismes unicellulaires et/ou des arthropodes pour les bâtiments, notamment sol, paras et/ou plafond, en particulier d'élevage, en présence ou non d'animaux. Selon l'invention, ladite composition contient au moins un acide gras.Other objects and advantages of the present invention will become apparent from the following description which is given for information only and which is not intended to limit it. The present invention relates to a pest control and / or disinfectant and / or insecticidal and / or insective and / or detergent composition for destroying and / or inhibiting unicellular organisms and / or arthropods for buildings, in particular soil, paras and / or ceiling , especially breeding, with or without animals. According to the invention, said composition contains at least one fatty acid.
Un des avantages de la présente composition telle que décrite dans la présente demande réside dans le fait qu'elle est dépourvue de toute toxicité et peut être utilisée pour désinfecter tous les locaux ou bâtiments d'élevage même en présence des animaux.One of the advantages of the present composition as described in the present application lies in the fact that it is devoid of any toxicity and can be used to disinfect all premises or livestock buildings even in the presence of animals.
Selon la présente invention, ladite composition telle que décrite dans la présente invention peut contenir, en outre, au moins un agent tensio actif.According to the present invention, said composition as described in the present invention may further contain at least one surfactant.
Par agent tensio actif, aussi appelé agent de surface, on entend tout composé qui modifie la tension superficielle entre deux surfaces.By surfactant, also called surfactant is meant any compound that modifies the surface tension between two surfaces.
Les composés tensio actifs sont des molécules amphiphiles, c'est-à-dire qui présentent deux parties de polarités différentes, l'une lipophile, miscible dans l'huile et apolaire, l'autre hydrophile, miscible dans l'eau et polaire.The surfactant compounds are amphiphilic molecules, i.e. have two parts of different polarities, one lipophilic, miscible in oil and apolar, the other hydrophilic, miscible in water and polar.
Une des fonctions des agents tensio-actifs selon la présente invention est de permettre la fixation de molécules hydrophobes, notamment les acides gras, afin de les mélanger avec des molécules hydrophiles, telles que l'eau améliorant ainsi le contact avec les parasites et, de ce fait, améliorant l'efficacité.One of the functions of the surfactants according to the present invention is to allow the attachment of hydrophobic molecules, in particular fatty acids, in order to mix them with hydrophilic molecules, such as water thus improving contact with the parasites, and this fact, improving efficiency.
Les acides gras sont des acides carboxyliques présentant une longue chaîne hydrophobe pouvant être saturée ou insaturée. Selon un mode particulier de la présente invention, l'acide gras est l'acide caprylique. L'acide caprylique, aussi connu comme acide octanoïque, est un acide gras saturé à chaîne linéaire comportant huit atomes de carbone. Il est notamment présent naturellement dans la noix de coco et le lait maternel, se présentant sous la forme d'un liquide huileux. En effet, les acides gras sont des produits naturels qu'on retrouve souvent dans notre alimentation.Fatty acids are carboxylic acids having a long hydrophobic chain that can be saturated or unsaturated. According to a particular embodiment of the present invention, the fatty acid is caprylic acid. Caprylic acid, also known as octanoic acid, is a linear-chain saturated fatty acid with eight carbon atoms. It is present naturally in coconut and breast milk, in the form of an oily liquid. Indeed, fatty acids are natural products that are often found in our diet.
Selon un autre mode de réalisation de la présente invention, l'acide gras est l'acide oléique. L'acide oléique est un des plus abondants des acides gras à chaîne longue, et se présente sous la forme d'un liquide (huile) qui ne se solidifie qu'à 4 0C.According to another embodiment of the present invention, the fatty acid is oleic acid. Oleic acid is one of the most abundant of long chain fatty acids, and is in the form of a liquid (oil) which only solidifies at 40.degree .
La composition telle que décrite dans la présente invention, peut contenir en outre au moins un biocide et/ou nettoyant.The composition as described in the present invention may further contain at least one biocide and / or cleaner.
Selon la présente invention, la composition telle que décrite peut contenir simultanément ou individuellement l'acide caprylique et l'acide oléique.According to the present invention, the composition as described may contain simultaneously or individually caprylic acid and oleic acid.
Selon un mode particulier de la présente invention, la composition telle qu'elle est décrite peut contenir en outre un diluant.According to a particular embodiment of the present invention, the composition as it is described may further contain a diluent.
Par diluant, on entent tout solvant organique et/ou aqueux, pouvant être ajouté à ladite composition sans altérer ses propriétés anti- parasitaires et/ou désinfectantes et/on insecticides et/on insectifuges et/ou détergentes. A titre d'exemple non limitatif, le tableau ci-dessous représenté présente les composants de deux compositions 1 et 2 différentes tels que décrits dans la présente invention, et la comparaison des résultats obtenus par ces compositions 1 et 2 et par la composition (A) commercialisée actuellement et contenant du phénol.By diluent is meant any organic and / or aqueous solvent, which can be added to said composition without altering its anti-parasitic and / or disinfectant properties and / or insecticides and / or insect repellents and / or detergents. By way of non-limiting example, the table below shows the components of two different compositions 1 and 2 as described in the present invention, and the comparison of the results obtained by these compositions 1 and 2 and by the composition (A ) currently marketed and containing phenol.
Figure imgf000005_0001
Figure imgf000005_0001
Les compositions telles que décrites dans la présente invention ont été testées en particulier contre les oocystes d'Eimeria tenella selon la protocole allemand du DGV. Après le temps de contact, l'action de la composition et du produit témoin est neutralisé par dilution . La quantité d'oocystes sporulés est comptabilisée. A chaque produit une valeur correspondant à sa capacité à réduire la quantité d'occystes est calculée partant d'une population de départ de 25000 oocystes.The compositions as described in the present invention have been tested in particular against Eimeria tenella oocysts according to the German DGV protocol. After the contact time, the action of the composition and the control product is neutralized by dilution. The amount of sporulated oocysts is counted. Each product has a value corresponding to its ability to reduce the amount of occyst is calculated from a starting population of 25,000 oocysts.
Tels que montrés au tableau ci-dessus mentionné, les résultats obtenus avec les compositions telles que décrites dans la présente invention sont tout à fait semblables à ceux obtenus avec la composition contenant du phénol. Au vu de ces résultats, l'action des acides gras est prouvée comme étant efficace pour l'éradication desdits oocystes et les inventeurs ont par ailleurs démontré que les compositions contenant des acides gras, notamment l'acide caprylique et l'acide oléique, sont au moins aussi efficaces qu'un produit à base de phénol.As shown in the table above mentioned, the results obtained with the compositions as described in the present invention are quite similar to those obtained with the phenol-containing composition. In view of these results, the action of the fatty acids is proven to be effective for the eradication of said oocysts and the inventors have furthermore demonstrated that the compositions containing fatty acids, in particular caprylic acid and oleic acid, are at least as effective as a phenol product.
Une telle composition, telle que décrite dans la présente invention est utilisée en tant que composition anti-parasitaire contre les organismes unicellulaires, notamment les protozoaires et en particulier les oocystes.Such a composition as described in the present invention is used as an anti-parasitic composition against unicellular organisms, especially protozoa and in particular oocysts.
Les oocystes se sont des protozoaires de type sporozoaires. Plus particulièrement, une telle composition, telle que décrite dans la présente invention est utilisée en tant que composition anti-parasitaire, notamment contre les arthropodes, tels que les poux rouges des poulaillers.Oocysts are protozoa of the sporozoal type. More particularly, such a composition, as described in the present invention is used as an anti-parasitic composition, especially against arthropods, such as red lice poultry houses.
En particulier, ladite composition est utilisée pour prévenir et/ou contrôler la coccidiose.In particular, said composition is used to prevent and / or control coccidiosis.
Encore selon la présente invention, une telle composition telle que décrite dans la présente invention peut être utilisée en tant que composition anti-parasitaire pour le traitement des surfaces notamment sols, parois et/ou plafonds de bâtiments d'élevage tels que le poulailler et/ou les étables.Still according to the present invention, such a composition as described in the present invention can be used as an anti-parasitic composition for the treatment of surfaces including floors, walls and / or ceilings of livestock buildings such as the chicken coop and / or or the stables.
En effet, afin d'éliminer ce type de parasite qui contaminent les bâtiments d'élevage et notamment les poulaillers et/ou les étables, une des façons les plus efficaces est d'appliquer par pulvérisation, thermobénulisation ou trempage les surfaces de ces bâtiments.Indeed, in order to eliminate this type of parasite that contaminate livestock buildings and especially poultry houses and / or stables, one of the most effective ways is to spray, thermobell or soak the surfaces of these buildings.
En outre, et selon la présente invention, ladite composition telle que décrite ci-dessus peut être utilisée en état pur ou dilué par ingestion et/ou par voie externe.In addition, and according to the present invention, said composition as described above can be used in pure state or diluted by ingestion and / or externally.
Selon les inventeurs, les compositions telles que décrites dans la présente invention permettent une réduction de 90 % des poux par simple contact, sous l'effet nocif des insecticides classiques actuellement interdits en présence d'animaux dans les élevages des poules pondeuses, ce qui n'est pas le cas de la présente composition.According to the inventors, the compositions as described in the present invention allow a reduction of 90% of the lice by simple contact, under the harmful effect of conventional insecticides currently prohibited in the presence of animals in the laying hen farms, which This is not the case with the present composition.
Naturellement, d'autres modes de réalisation de la présente invention, à la portée de l'homme de l'art, auraient pu être envisagés sans pour autant sortir du cadre de l'invention. Of course, other embodiments of the present invention, within the reach of those skilled in the art, could have been envisaged without departing from the scope of the invention.

Claims

REVENDICATIONS
1. Composition anti-parasitaire et/ou désinfectante et/ou détergente afin de détruire et/ou inhiber les protozoaires et en particulier la coccidiose et les spores de coccidiose dans les bâtiments, notamment sols, parois et/ou plafonds, en particulier d'élevage, en présence ou non d'animaux, caractérisée en ce qu'elle contient au moins un acide gras choisi parmi l'acide caprylique et l'acide oléique.1. An anti-parasitic and / or disinfecting and / or detergent composition for the purpose of destroying and / or inhibiting protozoa and in particular coccidiosis and coccidiosis spores in buildings, especially floors, walls and / or ceilings, in particular culture, in the presence or absence of animals, characterized in that it contains at least one fatty acid selected from caprylic acid and oleic acid.
2. Composition selon la revendication 1 , caractérisée en ce qu'elle contient en outre au moins un biocide et/ou agent nettoyant. 2. Composition according to claim 1, characterized in that it further contains at least one biocide and / or cleaning agent.
3. Composition selon la revendication 1 , caractérisée en ce qu'elle contient en outre un diluant.3. Composition according to claim 1, characterized in that it further contains a diluent.
4. Utilisation d'une composition selon l'une quelconque des revendications 1 à 3, en tant que composition anti-parasitaire pour le traitement des surfaces, notamment sols, parois, et/ou plafonds, de bâtiments d'élevage, tels que les poulaillers et/ou les étables. 4. Use of a composition according to any one of claims 1 to 3, as anti-parasitic composition for the treatment of surfaces, especially floors, walls, and / or ceilings, of livestock buildings, such as henhouses and / or stables.
PCT/EP2007/002779 2006-04-07 2007-03-29 Anti-parasitic and/or disinfectant and/or insect-repellent and/or detergent composition WO2007115691A1 (en)

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US10098098B2 (en) 2010-11-30 2018-10-09 Ecolab Usa Inc. Mixed fatty acid soap/fatty acid insecticidal, cleaning, and antimicrobial compositions

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