WO2007111233A1

WO2007111233A1 - Sheet-form pack and method of maintaining quality of sheet-form pack

Info

Publication number: WO2007111233A1
Application number: PCT/JP2007/055959
Authority: WO
Inventors: Takao Tehara; Masanori Ishiyama; Takayuki Sakamoto
Original assignee: Dhc Corporation; Taiki Corp., Ltd.
Priority date: 2006-03-24
Filing date: 2007-03-23
Publication date: 2007-10-04
Also published as: JP2007254423A; TW200812632A

Abstract

A sheet-form pack which comprises a support sheet and disposed thereon an aqueous gel composition containing a compound [I] and polyacrylic acid and/or a derivative thereof as essential ingredients. It is airtightly packaged in a packaging bag having oxygen-absorbing ability. The compound [I] is stable to alteration reactions in an acid region. The pack is hence effective in mitigating or eliminating pigmental spots resulting from the concentration/deposition of melanine, such as freckles and flecks. Use of a specific matrix enables the sheet-form pack to retain such performance over long on a high level. Also provided is an improved method of maintaining the quality of the pack.

Description

Sheet-shaped pack material and method for maintaining quality of sheet-shaped pack material

Technical field

[0001] The present invention is effective in improving and eliminating pigment spots caused by aggregation and deposition of melanin such as stains and freckles, and a sheet-like pack material capable of maintaining its performance at a high level for a long time in a specific matrix. And a method for maintaining the quality.

The present invention also relates to a sheet-like pack material that prevents odor and coloring generated in a specific matrix, and a method for maintaining the quality thereof.

More specifically, the present invention relates to a sheet-shaped pack material that is hermetically packaged in a packaging bag having an oxygen absorbing function, and a quality maintaining method thereof.

Background art

[0002] As an external preparation that is expected to prevent and improve melanin pigmented spots, it has an inhibitory action on melanin production, an agent containing ascorbic acid and its derivatives, etc., an inhibitory action on tyrosinase activity, hydroquinone or derivatives, polyphenols, kouji Agents containing acids or arbutins have been used.

However, these substances are positioned as antioxidants, and since they are easily oxidized, the inherent performance that is difficult to store for a long time is likely to deteriorate. It was insufficient.

Next, there is an attempt to use α-lipoic acid, which is a substance related to energy metabolism in vivo, but also has an antioxidative action with a strong active oxygen scavenging ability and an inhibitory action on melanin production, as a preventive measure for pigmentation. No. 11-79934 (Patent Document 1). In addition, as a therapeutic agent for pigmentation disorders, a technique using α-lipoic acid together with an ultraviolet absorber is disclosed in JP-T-2004-525186 (Patent Document 2).

However, OC lipoic acid is susceptible to dissolved oxygen in an aqueous medium and is unstable, and its application to the cosmetic field using an aqueous base material has been limited. In addition, an external preparation formulated with α-lipoic acid in a non-aqueous base material was not powerful enough to eliminate spots and freckles caused by melanin pigmentation. Therefore, the two sulfur atoms of α-lipoic acid are masked with metal atoms to stabilize the water-based substrate system, enhance the erasing function of melanin aggregation pigment deposits, and biosafety. WO2004 / 024139 (Patent Document 3) discloses a substance (lipoic acid derivative) having a structure in which the carboxyl terminal is amidated with histidine, and an application example.

[0003] The present inventors aim at the local elimination of melanin-like pigments such as shimoba buckwheat, aza, and mole, and perform application and imprinting operations on the skin surface as in conventional skin care cosmetics. The aim was to develop a water-based, water-based pack material that has a long-lasting effect by simply sticking, and has a high ODT (Occlusive Dressing Treatment) effect.

Contrary to expectations, however, when the lipoic acid derivative is blended in a matrix system using polyacrylic acid and Z or a derivative thereof as an aqueous gel base, the melanin pigment erasing ability that the compound originally has has a state of preservation. Phenomenon that is damaged in a short period of time, immediately after the preparation of the aqueous composition, a sulfur-containing compound-like odor occurs, does not disappear even after storage with the packaging material, and the gel composition coloration As a result of further research, it is considered that the denatured reaction is an oxidation reaction and a Z or decomposition reaction, and has an acidic range, particularly a PH value of 4 to 6.5. It was found to be accelerated significantly in the weakly acidic region.

[0004] Patent Document 1: Japanese Patent Laid-Open No. 11-79934

Patent Document 2: Special Table 2004-525186

Patent Document 3: WO2004 / 024139

Disclosure of the invention

Problems to be solved by the invention

[0005] In view of the above-mentioned problems, as a result of earnest research, it is preferred as a sheet-like pack material, and more particularly in the aqueous gel composition in the acidic region, especially in the production process of the polymer in polyacrylic acid and Z or a derivative thereof. In the presence of impurities due to water, it is surprising that the water-based gel can be obtained simply by airtight packaging in a packaging bag having an oxygen-absorbing function together with the pack material without adding a stabilizer or radical scavenger to the composition. Lipoic acid derivatives incorporated in the composition It has been found that the inactivation of the melanin pigment erasing ability is prevented, that the performance is maintained even after long-term storage, and that the off-flavor seen in sulfur-containing substances can be suppressed at the same time, and that coloring can be prevented. The invention has been reached. It has been found that the presence of a very small amount of impurities derived from the polymer in the acidic region can affect the quality of the pack material described above, and it is an object to provide a technique for maintaining the quality of the pack material for a long period of time. And

Means for solving the problem

That is, the present invention is based on the following configuration.

(1) A sheet-like pack material in which an aqueous gel composition containing the following compound [I] and polyacrylic acid and Z or a derivative thereof as essential components is disposed on a support sheet is placed in a packaging bag having an oxygen absorbing function. A sheet-like pack material, characterized in that the compound [I] is hermetically packaged and stabilized against a denaturation reaction in an acidic region.

[0007] [Chemical 3]

To compound]

[0008] (2) The sheet-shaped pack material as described in (1) above, wherein the modification reaction is a reaction caused by impurities contained in polyacrylic acid and Z or a derivative thereof.

(3) The sheet-like pack material according to (1) or (2) above, which is used for point care of the pack material.

(4) The content of the compound [I] is 0.01 to 5% by weight (based on an aqueous gel composition), according to the above (1) to (3), Sheet-like pack material.

(5) The packaging bag according to any one of the above (1) to (4), wherein the packaging bag is a bag in which a sheet body containing an iron-based oxygen absorbent is enclosed in a bag having gas barrier properties. The sheet-like pack material described in 1.

(6) The above packaging bag (1) to (4), wherein the packaging bag is formed of a laminated film force having (a) a gas barrier layer and (b) an absorption layer containing an iron-based oxygen absorbent. ) The sheet-like pack material described.

(7) A packaging bag having an oxygen-absorbing function as a sheet-like pack material in which a water-based gel composition containing compound [I] and polyacrylic acid and Z or a derivative thereof as essential components is disposed on a support sheet A method for maintaining the quality of a sheet-like pack material, characterized in that compound [I] is stabilized against a denaturation reaction in an acidic region by hermetically packaging the inside.

[0009] [Chemical 4]

Compound [I]

[0010] (8) The quality maintaining method of the sheet-like pack material according to (7), wherein the modification reaction is caused by impurities contained in polyacrylic acid and Z or a derivative thereof. Law.

(9) The sheet-like pack according to (7) or (8), wherein the method relates to at least one selected from prevention of discoloration, melanin deposition pigment elimination performance, and odor suppression How to maintain the quality of the material.

(10) The above-described (7) to (9), wherein the packaging bag is a bag in which a sheet body containing an iron-based oxygen absorbent is enclosed in a gas barrier bag. A method for maintaining the quality of the sheet-shaped pack material according to claim 1.

(11) The above (7) to (9), wherein the packaging bag is formed of a laminated film force having (a) a gas barrier layer and (b) an absorption layer containing an iron-based oxygen absorbent The quality maintenance method of the sheet-like pack material as described in any of the above.

The invention's effect

[0011] The sheet-like pack material of the present invention is a structure in which an aqueous gel composition is arranged on a support sheet, and unlike a pack material of a type in which a base material such as a nonwoven fabric is impregnated with a chemical solution, It is easy to handle without problems of contamination of clothes, clothes, bedding, and because it is highly safe, it can adhere to the skin for a long time, and the chemical solution may not evaporate due to body temperature, so the pack effect is high, It is possible to provide a sheet-like pack material.

The sheet of the present invention can be used conveniently even at bedtime, regardless of time or place. The gel composition layer that comes in contact with the skin is adjusted to a weakly acidic region that is gentle to the skin. Is possible.

[0012] When the pack material of the present invention is used for point care, if it is applied locally and concentrated to a site where agglomeration and pigmentation such as bruises, moles, stains and freckles have occurred, efficient care becomes possible. It can be preferably applied not only to the face but also to the parts damaged by ultraviolet rays such as the neck, shoulders, chest and arms.

The pack material of the present invention contains a component having a remarkably high melanin pigment erasing ability, and the erasing activity prevents a modification reaction of the lipoic acid derivative as an active ingredient in an acidic region preferable as a sheet-like pack material. Even if there is a trace amount of impurities that inevitably remain in the polyacrylic acid and Z or its derivative forming the adhesive part, the loss can be achieved without adding a stabilizer or a radical trapping agent. It is held in a high level state without being alive. Although it is such a simple pack material, it maintains the high-performance melanin erasing ability and exhibits the same effects as conventional whitening pack materials.

[0013] On the other hand, in the production of the sheet-like pack material of the present invention, by adopting a package form having an oxygen absorbing function, a special apparatus is not required, and a gel is obtained by utilizing a normal production line. Even in the presence of trace amounts of impurities in the polyacrylic acid and Z or its derivatives that form the composition, the modification reaction in the acidic region of the lipoic acid derivative can be prevented, leaving the product in high quality. It became possible for the first time to hold for a long time. In addition, it is possible to prevent the off-flavor specific to the sulfur-containing compounds generated in the production process, which is highly effective in terms of quality control.

BEST MODE FOR CARRYING OUT THE INVENTION

The best mode for carrying out the present invention will be described below.

The sheet-like pack material of the present invention has a structure in which an aqueous gel composition containing the following compound [I] and polyacrylic acid and Z or an derivative thereof as essential components is arranged on a support sheet. [0015] [Chemical 5]

Compound [I]

[0016] The components constituting the aqueous gel composition to be disposed in the sheet-like pack material of the present invention will be described.

Compound [I] can be produced, for example, by the method described in WO2004 / 024139. In addition to being excellent in the whitening effect represented by the melanin production inhibitory effect and the tyrosinase activity inhibitory effect, it is characterized by a markedly superior ability to eliminate the deposited pigment by aggregated melanin. The content of compound [I] is preferably in the range of 0.01 to 5% by weight. When the content is less than 0.01% by weight, the ability to remove the deposited pigment becomes small, and it becomes difficult to eliminate aggregated pigment spots such as stains, feathers, moles, and buckwheat. On the other hand, if it exceeds 5% by weight, the erasing ability is saturated and tends to be economically disadvantageous.

Examples of polyacrylic acid and Z or its derivatives used as thickening or sticking components include polyacrylic acid, salts of polyacrylic acid potassium salt, sodium salt, etc., partially neutralized polyacrylic acid, polymethacrylic acid , Polyacrylic acid ester, polyacrylamide, polymethacrylic acid ester, polymethacrylamide, or their copolymers, carboxyvinyl polymer, alkyl-modified carboxybule polymer, or acrylic acid (or its salt) · starch graft weight There are coalescence etc.

[0017] These polymers are thought to contain trace amounts of impurities derived from the polymerization initiator, and some of them are free-radical, so that the compound [I] is modified in a small amount. It is considered to be largely involved in the inhibition of the activity, particularly the erasing activity of the aggregated melanin deposition pigment. The modification reaction for the compound [I] is considered to be an oxidation reaction, a decomposition reaction, or a complex reaction thereof.

Examples of powerful polymerization initiators include persulfates such as sodium persulfate, potassium persulfate, ammonium persulfate, and hyde-peroxide compounds such as tamenno and id-peroxide. 1 Alkyl perester compounds such as 1-butylperoxy-2-ethylhexanate, peroxides such as hydrogen peroxide, 2,2'-azobisisobutyryl-tolyl, 4, A'-azobis (4 cyanopentanoic acid) Azo compounds such as 2,2'-azobis (2-methylbutyoxy-tolyl), 2,2azobis (2,4 dimethylvale-tolyl), and other benzoin alkyls such as benzoin methyl ether and benzoin isopropyl ether Examples include ethers or radical initiators such as aromatic oxyketones such as benzoin, benzyl, and benzophenone, and aromatic ketones.

[0018] If even a trace amount of the radical substance strength ppb to ppm level remains as an impurity, the modification reaction of the compound [I] unexpectedly occurs in a weakly acidic region where the PH value is around 4 to 6.5. Significantly accelerated.

In the aqueous gel composition, the impurities react with the compound [I] in the aqueous phase to cause a modification reaction, and it is considered that protons have a catalytic action for the modification reaction. Even without the addition of stabilizers, radical scavengers (scavengers), etc., there was an unexpected effect only with a simple packaging operation that physically and hermetically wraps with a packaging bag having an oxygen absorption function o

On the other hand, if the pH value exceeds ¾.5 and is adjusted to be neutral or alkaline site in order to suppress the intensive modification reaction, gelling is difficult and a practical pack material cannot be obtained. Also, if the PH value is below, the skin irritation tends to be strong, which is not preferable.

[0019] The aqueous gel composition includes animal and plant extracts usually used in cosmetics, quasi-drugs, etc., powder (wax and clay minerals), colorants, oils, polyhydric alcohols, sugars, silicon compounds , Amino acids, peptides, surfactants, thickeners, UV absorbers, preservatives, fragrances, moisturizers, bioactive substances (ceramides, hyaluronic acid and its salts, propolis, whitening agents, blood circulation promoters , Vitamins, anti-inflammatory agents, sebum suppressants, cooling agents, enzymes), clathrate compounds, salts, solvents, chelating agents, neutralizing agents or PH regulators, buffering agents, etc. These components can be blended.

The aqueous gel composition is placed on a support sheet by means such as plastering, coating, and casting. As the support sheet, any sheet selected from a woven fabric, a knitted fabric, a non-woven fabric, a film, a porous sheet, and a foam sheet may be used as long as it is a sheet that can hold the aqueous gel composition. Or two or more sheets may be used in combination.

When the support sheet is a liquid-permeable fibrous or porous substrate, the aqueous gel composition and the support sheet are integrated, and the support sheet is a liquid-impermeable substrate such as a film. In this case, a double-sided use type structure in which the aqueous gel composition and the support sheet can be separated is obtained. The double-sided use type is suitable for use since one side can be turned over and the other side can be used.

[0020] It is preferable from the viewpoints of storage stability and usability that the aqueous gel composition is disposed on the support sheet, and further a separator (release sheet) such as polyester, polyamide, and polyolefin is disposed thereon. This is because the aqueous gel composition has adhesiveness. The separator sheet is preferably subjected to a release coating such as silicone coating! /.

For shape stability as a sheet of the aqueous gel composition, as a crosslinking agent, aluminum potassium sulfate, aluminum chloride, dihydroxyaluminum aminoacetate, allanto chlorohydroxyaluminum, magnesium chloride, calcium chloride, oxidation A polyvalent metal salt such as zinc, magnesium oxide, magnesium hydroxide, aluminum hydroxide or iron hydroxide can be blended.

Various organic acids such as succinic acid, lactic acid, succinic acid, malic acid, or tartaric acid can be added to control the crosslinking reaction by these substances and to maintain the gel strength of the resulting crosslinked product. .

When a cross-linking agent is added, methods such as aging and curing can be used in combination in order to advance the cross-linking reaction.

The sheet-like pack material of the present invention can be molded into an arbitrary shape by means such as punching. Although it may be a full-face shape along the face, subsidence spots such as spots and freckles are usually limited to local areas, so they can be round, oval, square, jade, or any other geometric shape. It is preferably used for molded point care.

The powerful sheet-like pack material is hermetically packaged in a packaging bag having an oxygen absorbing function. As a preferred embodiment of the packaging bag, there are the following two methods (a) and (i).

(A) A bag in which a sheet body containing an iron-based oxygen absorbent is enclosed in a bag having gas barrier properties. (Ii) A bag formed from a laminated film comprising a gas barrier layer and an absorption layer containing an iron-based oxygen absorbent.

[0022] In the sheet body used in the method (a), for example, "Ageless" (Mitsubishi Gas Chemical Co., Ltd.), an oxygen-absorbing iron agent is enclosed in a breathable sheet material, and the periphery is surrounded. Examples include sealed ones. The sheet body and the sheet-like pack material are hermetically packaged in a bag made of a gas nori material. Examples of gas-nosie materials include highly crystalline polymer materials such as polyester and polyamide, and laminated films in which polyolefins and metal thin films such as aluminum are laminated. In particular, it is not particularly limited as long as it has a gas barrier property against oxygen and water vapor.

In the laminated film in the method (ii) above, the outer layer is a gas barrier layer, and the inner layer is provided with an absorption layer containing an iron-based oxygen absorbent. The laminated structure is not particularly limited as long as it has an oxygen absorbing function. A sheet-like pack material is accommodated and sealed using a powerful laminated film as an enveloping material.

[0023] In both cases (a) and (i), preferably, the inside of the bag is evacuated or replaced with an inert gas such as nitrogen or argon gas when the bag is formed and sealed.

By vigorously and hermetically wrapping, the water-based gel composition of the knocking material can effectively maintain the activity of the compound [I] without adding a stabilizer or a radical scavenger, For the first time, the purpose of suppressing odor caused by compound [I] can be achieved.

[0024] [Example]

Hereinafter, the present invention will be described in more detail with reference to examples.

Example 1

[0025] As an active ingredient for eliminating melanin deposition pigment, 0.5% by weight of the above-mentioned compound [I] and as a thickening ingredient of a gel composition, sodium polyacrylate (60 mol% partially neutralized product) 12% % and were prepared aqueous composition containing dihydroxy aluminum § amino acetate 0.10 ^_0/0 as a crosslinking agent component (PH value 5.1).

This composition was cast on a support sheet having a polyester nonwoven fabric (weight per unit area: 50 gZm ² ) force, and then a PET film (thickness 80 m) was laminated on the surface of the composition as a separator sheet. The support sheet of this sheet and the gel composition layer part were formed into a circular shape (25 mmΦ) by punching to produce a sheet-shaped pack material for point care.

This pack material was sealed in a pouch packaging bag using “Ageless' O Mac” (Mitsubishi Gas Chemical Co., Ltd.), which is a sheet packaging material in which a gas layer and an oxygen absorption layer are laminated, and an airtight seal was provided. Later, it was aged.

The sheet-like pack material in a packaging bag obtained by struggling is stored at 40 ° C for 2 months as an accelerated test of quality stability, and the gel composition after storage (color judgment (visual judgment)) and accompanying sunburn The melanin deposition pigment removal performance and the odor at the time of opening (olfaction judgment) were evaluated.

Table 1 shows the evaluation results.

Even after the accelerated test, the gel composition is not discolored and has no odor.

In addition, the pack material of the present invention is affixed to the spot of the melanin deposition pigment that has developed in the neck every night at bedtime, and is used for 3 months. The spot-like “stains” disappeared completely.

Thus, even in the acidic region, Compound [I] was completely unaffected by the denaturation reaction.

Example 2

As an active ingredient for melanin pigment elimination, 1.5% by weight of the above compound [I], as a thickening ingredient of the gel composition, 9% by weight of sodium polyacrylate (60 mol% partially neutralized product) and starch 'An aqueous composition containing 3% by weight of sodium acrylate graft polymer and 0.10% by weight of sodium chloride as a crosslinking agent component was prepared (PH value 5.9).

This composition was cast on a support sheet made of a laminated sheet of polyamide tricot knitted fabric and polyurethane film (weight per unit area: 7 OgZm ² ), and then a PET film (thickness 75 μm) as a separator sheet on the composition surface. m) was laminated.

The support sheet of this sheet and the gel composition layer portion were formed into a slanting shape by punching to produce a sheet-shaped pack material for eye care.

This knocking material was sealed in a bouch packaging bag using gas nolia film together with oxygen absorber “AGELESS” (Mitsubishi Gas Chemical Co., Ltd.), and after aging overnight after airtight sealing. The sheet-shaped pack material with packaging bags obtained by force is used as an accelerated test for quality stability. The gel composition was stored for 2 months at ° C, and the colorability (visual determination) of the gel composition after storage, the ability to remove melanin pigments generated by sunburn, and the odor at the time of opening (olfaction determination) were evaluated. Table 1 shows the evaluation results.

Even after the accelerated test, the gel composition was not discolored and there was almost no odor.

In addition, the pack material of the present invention was applied to the other part of the melanin deposition pigment that occurred under the eyes every night at bedtime and was used regularly for 3 months. The “aza” disappeared completely.

Thus, compound [I] was completely unaffected by the denaturation reaction even in the acidic region.

Example 3

As an active ingredient for eliminating melanin pigment, 2.5% by weight of the above compound [I], as a thickening component of the gel composition, 11% by weight of sodium polyacrylate (60 mol% partially neutralized product) and starch 'An aqueous composition containing 1% by weight of a sodium acrylate graft polymer and 0.10% by weight of sodium salt as a crosslinking agent component was prepared (PH value 5.5).

After casting this composition on a polyethylene film (thickness 20 μm), a PET film (thickness 80 μm) was laminated as a separator sheet on the composition surface.

This polyethylene film and the gel composition layer were punched into a full face shape having eyes, nose and mouth to produce a sheet-like pack material.

The sheet-like pack material in a packaging bag obtained by struggling is stored at 40 ° C for 2 months as an accelerated test of quality stability, and the gel composition after storage (color judgment (visual judgment)) and accompanying sunburn The melanin pigment removal performance that occurred and the odor (olfaction judgment) at the time of opening were evaluated. Table 1 shows the evaluation results.

In addition, the pack material of the present invention should be affixed to the face every night at bedtime, making use of both front and back sides. However, after two months of regular use, the spotted “spots” and “sobacas” of the deposited pigment scattered on the face before the start of the test disappeared completely.

[Comparative Example 1]

As an active ingredient for melanin pigment elimination, 1.5% by weight of the above compound [I], as a thickening ingredient of the gel composition, 9% by weight of sodium polyacrylate (60 mol% partially neutralized product) and starch 'An aqueous composition containing 3% by weight of sodium acrylate graft polymer and 0.10% by weight of sodium salt as a crosslinking agent component was prepared (PH value 5.6).

This composition was cast on a support sheet having a nylon non-woven fabric (weight per unit area: 40 g / m ² ) force, and then a PET film (thickness 75 μm) was laminated as a separator sheet on the surface of the composition. The support sheet and the gel composition layer were formed into an oval shape by punching to produce a sheet-like pack material for point care.

This pack material was sealed in a pouch packaging bag using a polypropylene film (thickness 250 m) without encapsulating an oxygen scavenger, and hermetically sealed, and then aged overnight.

After the accelerated test, the gel composition was discolored from yellow to brown, and the sulfur odor was noticeable.

In addition, this pack material was applied to the “stain” portion of the melanin deposition pigment that had developed in the buttock every night at bedtime, and was used regularly for 3 months.

Thus, compound [I] was significantly affected by the denaturation reaction.

[Comparative Example 2]

As an active ingredient for melanin pigment elimination, 1.5% by weight of the above compound [I], as a thickening ingredient of the gel composition, 9% by weight of sodium polyacrylate (60 mol% partially neutralized product) and starch 'Sodium acrylate graft polymer 3% by weight, salter as crosslinker component Lumi - © beam 0.10 ^_0/0, and further produced as the blocking agent (scavenger) EDTA aqueous composition containing (ethylenediamine tetraacetic acid) (PH value 5.8).

This composition was cast on a support sheet having a polypropylene non-woven fabric (weight per unit area: 40 g / m ² ) force, and then a PET film (thickness: 85 μm) was laminated on the surface of the composition as a separator sheet.

The support sheet of this sheet and the gel composition layer were formed into an oval shape by punching to produce a point-like sheet-like pack material.

The pack material was sealed in a bouch packaging bag using a gas barrier film without encapsulating an oxygen scavenger, and hermetically sealed, and then aged overnight.

After the accelerated test, the gel composition was discolored to a yellow level, and the sulfur odor was a concern.

In addition, when this pack material was applied to the “stain” portion of the melanin deposition pigment that had developed in the buttocks every night at bedtime and was used regularly for 3 months, a significant improvement effect was obtained although the “stain” was somewhat reduced. There was no.

Thus, compound [I] was affected by the denaturation reaction.

(Comparative Example 3)

As an effective ingredient for eliminating melanin pigment, a Lipoic acid 1.5% by weight, Gel composition thickening ingredient Sodium polyacrylate (60 mol% partially neutralized) 9% by weight An aqueous composition was prepared by blending 3% by weight of sodium acrylate graft polymer and 0.10% by weight of salt aluminum as a crosslinking agent component.

This composition was cast on a support sheet made of a polyester nonwoven fabric (weight per unit: 50 gZm ² ), and then a PET film (thickness 80 m) was laminated as a separator sheet on the surface of the composition.

By punching the support sheet of this sheet and the gel composition layer part into an elliptical shape The sheet-shaped pack material for point care was manufactured.

This knocking material is sealed with “AGELESS” (Mitsubishi Gas Chemical Co., Ltd.) as an oxygen scavenger, and as a packaging material, “Ageless“ Omag ”( The product was sealed in a bouch packaging bag using Mitsubishi Gas Chemical Co., Ltd., hermetically sealed, and then aged.

After the accelerated test, discoloration and off-flavor of the gel composition were not recognized. However, this pack material was affixed to the “stain” portion of the melanin deposition pigment that had appeared on the forehead every night at bedtime and was used regularly for 3 months.

[table 1]

A: tress * 卜 ku (Mitsubishi Gas Chemical registered trademark) B: oxygen absorber seal bag “Tre (Mitsubishi Gas Chemical registered trademark)

[Chromaticity] O: Not colored Δ: Slightly yellowed X: Significantly yellowed

[! Rakon-sinking pigment erasing performance / applied at bedtime, after 3 months of continuous use] @: disappearance of pigment spots O: discoloration of faint spots Δ: slight reduction of faint spots X:

Claims

Claims [1] A sheet-like pack material in which an aqueous gel composition containing the following compound [i] and polyacrylic acid and Z or a derivative thereof as essential components is disposed on a support sheet has an oxygen absorbing function. A sheet-shaped pack material, characterized in that the compound [I] is hermetically packaged in a packaging bag and stabilized against a denaturation reaction in an acidic region.

[Chemical 1]

Compound [I]

[2] The sheet-like pack material according to [1], wherein the modification reaction is a reaction caused by impurities contained in polyacrylic acid and Z or a derivative thereof.

[3] The sheet-like pack material according to claim 1 or 2, wherein the pack material is used for point care.

[4] The sheet-shaped pack material according to any one of claims 1 to 3, wherein the content of the compound [I] is 0.01 to 5% by weight (based on an aqueous gel composition).

[5] The sheet according to any one of claims 1 to 4, wherein the packaging bag is a bag in which a sheet body containing an iron-based oxygen absorbent is enclosed in a bag having gas barrier properties. Packing material.

6. The packaging bag according to claim 1, wherein the packaging bag is formed of a laminated film force having (a) a gas barrier layer and (b) an absorption layer containing an iron-based oxygen absorbent. The sheet-like pack material according to any one of the above.

[7] Aqueous gel composition containing compound [I] and polyacrylic acid and Z or a derivative thereof as essential components A sheet-like pack material arranged on a support sheet is placed in a packaging bag having an oxygen absorbing function. A method for maintaining the quality of a sheet-like pack material, characterized in that compound [I] is stabilized against a denaturation reaction in an acidic region by air-tight packaging.

[Chemical 2]

Compound [I]

8. The method for maintaining the quality of a sheet-like pack material according to claim 7, wherein the modification reaction is caused by impurities contained in polyacrylic acid and Z or a derivative thereof.

[9] The quality of the sheet-like pack material according to claim 7 or 8, wherein the method relates to at least one selected from prevention of discoloration, melanin deposition pigment elimination performance, and odor suppression. Retention method.

10. The sheet according to any one of claims 7 to 9, wherein the packaging bag is a bag in which a sheet body containing an iron-based oxygen absorbent is enclosed in a bag having gas barrier properties. To maintain the quality of the packing material.

[11] The packaging bag according to any one of claims 7 to 9, wherein the packaging bag is formed from a laminated film having an absorption layer containing (a) a gas barrier layer and (b) an iron-based oxygen absorbent. The quality maintenance method of the sheet-like pack material described in any one.