WO2007110624A3 - Reactif immobilise - Google Patents
Reactif immobilise Download PDFInfo
- Publication number
- WO2007110624A3 WO2007110624A3 PCT/GB2007/001089 GB2007001089W WO2007110624A3 WO 2007110624 A3 WO2007110624 A3 WO 2007110624A3 GB 2007001089 W GB2007001089 W GB 2007001089W WO 2007110624 A3 WO2007110624 A3 WO 2007110624A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- immobilised
- immobilised reagent
- phosphorus
- atom
- cyclic
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 3
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical group P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 2
- 125000005328 phosphinyl group Chemical group [PH2](=O)* 0.000 abstract 1
- 238000005731 phosphitylation reaction Methods 0.000 abstract 1
- -1 phosphoryl moiety Chemical group 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
Abstract
L'invention concerne un réactif cyclique immobilisé de phosphitylation ou de phosphorylation, comprenant une fonction phosphinyle ou phosphoryle, l'atome de phosphore (III) ou l'atome de phosphore (V) étant respectivement lié à et dans un système cyclique.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0606038A GB0606038D0 (en) | 2006-03-27 | 2006-03-27 | Immobilised reagent |
GB0606038.8 | 2006-03-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007110624A2 WO2007110624A2 (fr) | 2007-10-04 |
WO2007110624A3 true WO2007110624A3 (fr) | 2008-04-03 |
Family
ID=36384204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2007/001089 WO2007110624A2 (fr) | 2006-03-27 | 2007-03-26 | Reactif immobilise |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB0606038D0 (fr) |
WO (1) | WO2007110624A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102009012640A1 (de) * | 2009-03-09 | 2010-09-30 | Freie Universität Berlin | Mit einer Phosphoamidatgruppe modifizierte Verbindung und deren Verwendung |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003008432A1 (fr) * | 2001-07-16 | 2003-01-30 | Isis Pharmaceuticals, Inc. | Procede de preparation de nucleosides triphosphates modifies en position alpha et composes obtenus conformement a ce procede |
-
2006
- 2006-03-27 GB GB0606038A patent/GB0606038D0/en not_active Ceased
-
2007
- 2007-03-26 WO PCT/GB2007/001089 patent/WO2007110624A2/fr active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003008432A1 (fr) * | 2001-07-16 | 2003-01-30 | Isis Pharmaceuticals, Inc. | Procede de preparation de nucleosides triphosphates modifies en position alpha et composes obtenus conformement a ce procede |
Non-Patent Citations (2)
Title |
---|
BURGESS, K. AND COOK, D.: "Synthesis of nucleoside triphosphates", CHEM. REV., vol. 100, 2000, pages 2047 - 2059, XP002464530 * |
PARANG, K. ET AL.: "Selective diphosphorylation, dithiodiphosphorylation, triphosphorylation, and trithiotriphosphorylation of unprotected carbohydrates and nucleosides", ORG. LETT., vol. 7, 2005, pages 5589 - 5592, XP002464531 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007110624A2 (fr) | 2007-10-04 |
GB0606038D0 (en) | 2006-05-03 |
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