WO2007104992A8 - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

Info

Publication number
WO2007104992A8
WO2007104992A8 PCT/GB2007/000905 GB2007000905W WO2007104992A8 WO 2007104992 A8 WO2007104992 A8 WO 2007104992A8 GB 2007000905 W GB2007000905 W GB 2007000905W WO 2007104992 A8 WO2007104992 A8 WO 2007104992A8
Authority
WO
WIPO (PCT)
Prior art keywords
electric
electric sector
mass analyser
sector
sectors
Prior art date
Application number
PCT/GB2007/000905
Other languages
French (fr)
Other versions
WO2007104992A3 (en
WO2007104992A2 (en
Inventor
Jeffery Mark Brown
Original Assignee
Micromass Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass Uk Limited filed Critical Micromass Uk Limited
Priority to JP2008558899A priority Critical patent/JP5162479B2/en
Priority to US12/282,394 priority patent/US7863557B2/en
Priority to CA2645651A priority patent/CA2645651C/en
Priority to EP07712900.5A priority patent/EP2002461B1/en
Publication of WO2007104992A2 publication Critical patent/WO2007104992A2/en
Publication of WO2007104992A3 publication Critical patent/WO2007104992A3/en
Publication of WO2007104992A8 publication Critical patent/WO2007104992A8/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H01J49/408—Time-of-flight spectrometers with multiple changes of direction, e.g. by using electric or magnetic sectors, closed-loop time-of-flight
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

A multi-turn Time of Flight mass analyser is disclosed comprising a first electric sector (5) and a second electric sector (8). The second electric sector (8) is arranged orthogonal to the first electric sector (5). Ions may make multiple loops or circuits of the mass analyser before being detected and mass analysed enabling a high resolution mass analyser to be provided. According to another embodiment the mass analyser may have an open-loop geometry wherein the first electric sector is elongated and further electric sectors are arranged in a staggered manner along the length of the first electric sector. The first and second electric sectors (5,8) may be sub-divided into a plurality of electric sector segments.
PCT/GB2007/000905 2006-03-14 2007-03-14 Mass spectrometer WO2007104992A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2008558899A JP5162479B2 (en) 2006-03-14 2007-03-14 Mass spectrometer
US12/282,394 US7863557B2 (en) 2006-03-14 2007-03-14 Mass spectrometer
CA2645651A CA2645651C (en) 2006-03-14 2007-03-14 Mass spectrometer
EP07712900.5A EP2002461B1 (en) 2006-03-14 2007-03-14 Mass spectrometer

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0605089.2A GB0605089D0 (en) 2006-03-14 2006-03-14 Mass spectrometer
GB0605089.2 2006-03-14
US78710106P 2006-03-29 2006-03-29
US60/787,101 2006-03-29

Publications (3)

Publication Number Publication Date
WO2007104992A2 WO2007104992A2 (en) 2007-09-20
WO2007104992A3 WO2007104992A3 (en) 2008-08-07
WO2007104992A8 true WO2007104992A8 (en) 2013-03-14

Family

ID=36292709

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/000905 WO2007104992A2 (en) 2006-03-14 2007-03-14 Mass spectrometer

Country Status (6)

Country Link
US (1) US7863557B2 (en)
EP (2) EP2688088B1 (en)
JP (1) JP5162479B2 (en)
CA (2) CA2821097C (en)
GB (5) GB0605089D0 (en)
WO (1) WO2007104992A2 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4980583B2 (en) * 2004-05-21 2012-07-18 日本電子株式会社 Time-of-flight mass spectrometry method and apparatus
CN101669027B (en) * 2007-05-09 2013-09-25 株式会社岛津制作所 Charged particle analyzer
CN101158641B (en) * 2007-11-21 2010-06-02 中国科学院武汉物理与数学研究所 Non-collinear mass resolution critical point threshold electric dissociation spectrometer
GB2455977A (en) * 2007-12-21 2009-07-01 Thermo Fisher Scient Multi-reflectron time-of-flight mass spectrometer
US7932487B2 (en) * 2008-01-11 2011-04-26 Thermo Finnigan Llc Mass spectrometer with looped ion path
GB2462065B (en) * 2008-07-17 2013-03-27 Kratos Analytical Ltd TOF mass spectrometer for stigmatic imaging and associated method
JP2010033735A (en) * 2008-07-25 2010-02-12 Jeol Ltd Quadrupole mass spectroscope
WO2010038260A1 (en) * 2008-10-02 2010-04-08 株式会社島津製作所 Multi-turn time-of-flight mass spectrometer
US9653277B2 (en) * 2008-10-09 2017-05-16 Shimadzu Corporation Mass spectrometer
GB2470600B (en) 2009-05-29 2012-06-13 Thermo Fisher Scient Bremen Charged particle analysers and methods of separating charged particles
GB2470599B (en) * 2009-05-29 2014-04-02 Thermo Fisher Scient Bremen Charged particle analysers and methods of separating charged particles
GB2476964A (en) * 2010-01-15 2011-07-20 Anatoly Verenchikov Electrostatic trap mass spectrometer
GB201118279D0 (en) 2011-10-21 2011-12-07 Shimadzu Corp Mass analyser, mass spectrometer and associated methods
GB201118270D0 (en) 2011-10-21 2011-12-07 Shimadzu Corp TOF mass analyser with improved resolving power
DE102013011462B4 (en) * 2013-07-10 2016-03-31 Bruker Daltonik Gmbh Time-of-Flight Mass Spectrometer with Cassini Reflector
GB201507363D0 (en) 2015-04-30 2015-06-17 Micromass Uk Ltd And Leco Corp Multi-reflecting TOF mass spectrometer
GB201519830D0 (en) * 2015-11-10 2015-12-23 Micromass Ltd A method of transmitting ions through an aperture
GB201520134D0 (en) 2015-11-16 2015-12-30 Micromass Uk Ltd And Leco Corp Imaging mass spectrometer
GB201520130D0 (en) 2015-11-16 2015-12-30 Micromass Uk Ltd And Leco Corp Imaging mass spectrometer
GB201520540D0 (en) 2015-11-23 2016-01-06 Micromass Uk Ltd And Leco Corp Improved ion mirror and ion-optical lens for imaging
DE102015121830A1 (en) * 2015-12-15 2017-06-22 Ernst-Moritz-Arndt-Universität Greifswald Broadband MR-TOF mass spectrometer
GB201613988D0 (en) 2016-08-16 2016-09-28 Micromass Uk Ltd And Leco Corp Mass analyser having extended flight path
GB2567794B (en) 2017-05-05 2023-03-08 Micromass Ltd Multi-reflecting time-of-flight mass spectrometers
GB2563571B (en) 2017-05-26 2023-05-24 Micromass Ltd Time of flight mass analyser with spatial focussing
WO2019030473A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov Fields for multi-reflecting tof ms
WO2019030475A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov Multi-pass mass spectrometer
WO2019030472A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov Ion mirror for multi-reflecting mass spectrometers
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
WO2019030474A1 (en) 2017-08-06 2019-02-14 Anatoly Verenchikov Printed circuit ion mirror with compensation
US11081332B2 (en) 2017-08-06 2021-08-03 Micromass Uk Limited Ion guide within pulsed converters
EP3662503A1 (en) 2017-08-06 2020-06-10 Micromass UK Limited Ion injection into multi-pass mass spectrometers
GB201806507D0 (en) 2018-04-20 2018-06-06 Verenchikov Anatoly Gridless ion mirrors with smooth fields
GB201807626D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201807605D0 (en) 2018-05-10 2018-06-27 Micromass Ltd Multi-reflecting time of flight mass analyser
GB201808530D0 (en) 2018-05-24 2018-07-11 Verenchikov Anatoly TOF MS detection system with improved dynamic range
GB201810573D0 (en) * 2018-06-28 2018-08-15 Verenchikov Anatoly Multi-pass mass spectrometer with improved duty cycle
GB201901411D0 (en) 2019-02-01 2019-03-20 Micromass Ltd Electrode assembly for mass spectrometer
WO2020248757A1 (en) * 2019-06-14 2020-12-17 Shanghai Polaris Biology Co., Ltd. Systems and methods for single particle analysis
GB2598591A (en) * 2020-09-03 2022-03-09 HGSG Ltd Mass spectrometer and method
GB2605775A (en) * 2021-04-07 2022-10-19 HGSG Ltd Mass spectrometer and method
JP2022177560A (en) * 2021-05-18 2022-12-01 国立大学法人東北大学 electron spectrometer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3571566B2 (en) * 1999-02-19 2004-09-29 日本電子株式会社 Ion optical system of time-of-flight mass spectrometer
JP3761752B2 (en) * 1999-11-10 2006-03-29 日本電子株式会社 Time-of-flight mass spectrometer with orbit
KR20020073953A (en) * 2001-03-17 2002-09-28 이토마토투자자문 주식회사 offering method for buying and selling index of stocks item by real time in internet
US6867414B2 (en) * 2002-09-24 2005-03-15 Ciphergen Biosystems, Inc. Electric sector time-of-flight mass spectrometer with adjustable ion optical elements
AU2003276409A1 (en) * 2002-11-15 2004-06-15 Micromass Uk Limited Mass spectrometer
KR100478103B1 (en) * 2002-11-28 2005-03-25 문해령 A Method for Providing a Technical Stock Index Using % Disparity Rate
JP4182844B2 (en) 2003-09-03 2008-11-19 株式会社島津製作所 Mass spectrometer
JP4001100B2 (en) * 2003-11-14 2007-10-31 株式会社島津製作所 Mass spectrometer
US7326925B2 (en) * 2005-03-22 2008-02-05 Leco Corporation Multi-reflecting time-of-flight mass spectrometer with isochronous curved ion interface

Also Published As

Publication number Publication date
EP2002461B1 (en) 2014-11-05
GB0808829D0 (en) 2008-06-18
GB2456089B (en) 2009-09-23
GB2437609B (en) 2009-02-18
GB2447160B (en) 2009-06-24
CA2821097A1 (en) 2007-09-20
GB2453468A (en) 2009-04-08
EP2002461A2 (en) 2008-12-17
WO2007104992A3 (en) 2008-08-07
EP2688088A3 (en) 2014-06-18
US7863557B2 (en) 2011-01-04
GB0905773D0 (en) 2009-05-20
EP2688088B1 (en) 2018-06-13
JP5162479B2 (en) 2013-03-13
CA2645651C (en) 2013-09-24
WO2007104992A2 (en) 2007-09-20
GB2456089A (en) 2009-07-08
CA2821097C (en) 2015-11-24
CA2645651A1 (en) 2007-09-20
GB0704925D0 (en) 2007-04-25
EP2688088A2 (en) 2014-01-22
GB2447160A (en) 2008-09-03
GB0605089D0 (en) 2006-04-26
GB0900459D0 (en) 2009-02-11
GB2453468B (en) 2009-06-03
JP2009530761A (en) 2009-08-27
US20090314934A1 (en) 2009-12-24
GB2437609A (en) 2007-10-31

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