WO2007096740A3 - Novel cephalosporins - Google Patents

Novel cephalosporins Download PDF

Info

Publication number
WO2007096740A3
WO2007096740A3 PCT/IB2007/000403 IB2007000403W WO2007096740A3 WO 2007096740 A3 WO2007096740 A3 WO 2007096740A3 IB 2007000403 W IB2007000403 W IB 2007000403W WO 2007096740 A3 WO2007096740 A3 WO 2007096740A3
Authority
WO
WIPO (PCT)
Prior art keywords
general formula
present
formula
novel cephalosporins
novel
Prior art date
Application number
PCT/IB2007/000403
Other languages
French (fr)
Other versions
WO2007096740A2 (en
Inventor
Uma Ramachandran
Gaddam Om Reddy
Ravikumar Tadiparthi
Prabhakar Theratipally
Jakkala Venkateshwarlu
Santhosh Subramanian
Original Assignee
Orchid Res Lab Ltd
Uma Ramachandran
Gaddam Om Reddy
Ravikumar Tadiparthi
Prabhakar Theratipally
Jakkala Venkateshwarlu
Santhosh Subramanian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Res Lab Ltd, Uma Ramachandran, Gaddam Om Reddy, Ravikumar Tadiparthi, Prabhakar Theratipally, Jakkala Venkateshwarlu, Santhosh Subramanian filed Critical Orchid Res Lab Ltd
Publication of WO2007096740A2 publication Critical patent/WO2007096740A2/en
Publication of WO2007096740A3 publication Critical patent/WO2007096740A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Abstract

The present invention relates to novel compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. The present invention more particularly provides novel cephalosporin antibiotics of the general formula (I). Also included is a method for treatment of infectious diseases in a mammal comprising administering an effective amount of a compound of formula (I) as described above.
PCT/IB2007/000403 2006-02-20 2007-02-20 Novel cephalosporins WO2007096740A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN266CH2006 2006-02-20
IN266/CHE/2006 2006-02-20

Publications (2)

Publication Number Publication Date
WO2007096740A2 WO2007096740A2 (en) 2007-08-30
WO2007096740A3 true WO2007096740A3 (en) 2007-10-18

Family

ID=38437742

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000403 WO2007096740A2 (en) 2006-02-20 2007-02-20 Novel cephalosporins

Country Status (1)

Country Link
WO (1) WO2007096740A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2935651A1 (en) 2007-10-09 2009-04-16 Gladius Pharmaceuticals Corporation Broad spectrum beta-lactamase inhibitors
RS55365B1 (en) 2008-10-31 2017-03-31 Shionogi & Co Cephalosporin having catechol group
CN102918047A (en) 2010-04-05 2013-02-06 盐野义制药株式会社 Cephem compound having pseudo-catechol group
RU2012146986A (en) 2010-04-05 2014-05-20 Сионоги Энд Ко., Лтд. CEPHEMIC COMPOUNDS CONTAINING A CATHOLIC GROUP
JP5852562B2 (en) 2010-04-28 2016-02-03 塩野義製薬株式会社 Novel cephem derivatives
WO2012147773A1 (en) * 2011-04-28 2012-11-01 塩野義製薬株式会社 Novel cephem compound having catechol or pseudo-catechol structure
CN103619853A (en) 2011-06-27 2014-03-05 盐野义制药株式会社 Cephem compound having pyridinium group
WO2013051597A1 (en) 2011-10-04 2013-04-11 塩野義製薬株式会社 Cephem derivative having catechol group
AU2013339040A1 (en) 2012-10-29 2015-04-30 Shionogi & Co., Ltd. Processes for production of intermediates for 2-alkyl cephem compounds
CN106967093B (en) * 2017-03-31 2019-05-17 成都大学 A kind of cephalosporin compound and its preparation method and application

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137440A2 (en) * 1983-10-08 1985-04-17 Hoechst Aktiengesellschaft Cephalasporin derivatives and process for their preparation
JPS6230788A (en) * 1985-08-02 1987-02-09 Banyu Pharmaceut Co Ltd Novel cephalosporin derivative
JPH01279893A (en) * 1988-04-28 1989-11-10 Fujisawa Pharmaceut Co Ltd Cephem compound
WO1992018508A1 (en) * 1991-04-15 1992-10-29 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds
US5571909A (en) * 1993-06-09 1996-11-05 Korea Institute Of Science And Technology Cephalosporin compounds and processes for preparing thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137440A2 (en) * 1983-10-08 1985-04-17 Hoechst Aktiengesellschaft Cephalasporin derivatives and process for their preparation
DE3409431A1 (en) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
JPS6230788A (en) * 1985-08-02 1987-02-09 Banyu Pharmaceut Co Ltd Novel cephalosporin derivative
JPH01279893A (en) * 1988-04-28 1989-11-10 Fujisawa Pharmaceut Co Ltd Cephem compound
WO1992018508A1 (en) * 1991-04-15 1992-10-29 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds
US5571909A (en) * 1993-06-09 1996-11-05 Korea Institute Of Science And Technology Cephalosporin compounds and processes for preparing thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS [online] accession no. STN Database accession no. (103:160295) *
DATABASE CAPLUS [online] accession no. STN Database accession no. (103:215071) *
DATABASE CAPLUS [online] accession no. STN Database accession no. (107:115433) *
DATABASE CAPLUS [online] accession no. STN Database accession no. (112:216552) *
DATABASE CAPLUS [online] accession no. STN Database accession no. (126:59805) *
DATABASE CAPLUS [online] WATANABE K. AND KATSU K.: "Affinity of E1077, a new cephalosporin, for penicillin-binding proteins of Staphylococcus aureus and its antistaphylococcal activity", accession no. STN Database accession no. (121:4889) *
JOURNAL OF ANTIBIOTICS, vol. 46, no. 11, 1993, pages 1707 - 1715 *

Also Published As

Publication number Publication date
WO2007096740A2 (en) 2007-08-30

Similar Documents

Publication Publication Date Title
WO2007096740A3 (en) Novel cephalosporins
WO2007042912A3 (en) Heterocyclic compounds as pstat3/il-6 inhibitors
WO2007109578A3 (en) Substituted gamma lactams as prostaglandin ep2 agonists
SG10201806714PA (en) C7-fluoro substituted tetracycline compounds
WO2006113509A3 (en) Quinobenzoxazine analogs and methods of using thereof
WO2010105179A3 (en) Inhibitors of beta-secretase
TW200833675A (en) Nicotinamide derivatives
WO2009053808A3 (en) Histone deacetylase inhibitors
CA2665931C (en) Hydrobenzamide derivatives as inhibitors of hsp90
MY148703A (en) Polycyclic cinnamide derivatives
WO2007122634A3 (en) Pyrimidinediones as tyrosine kinase inhibitors
DE602005019316D1 (en) Aromatische etherderivate als thrombin-hemmer
WO2010129057A3 (en) Tetracycline compounds
MX2009012125A (en) Therapeutic compounds.
WO2008155615A3 (en) An improved process for the preparation of cephalosporin antibiotic
WO2011025982A3 (en) Tetracycline compounds
WO2007054776A3 (en) Stilbene like compounds as novel hdac inhibitors
MY148847A (en) 5-hydroxymethyl-oxazolidin-2-one derivatives
WO2007045962A3 (en) Novel hdac inhibitors
WO2010132670A3 (en) Pentacycline compounds
EA200870224A1 (en) BENZO [F] IZININDOL-2-ILPHENYL ACID ACETIC DERIVATIVES AS AN AGONISTS EP EP RECEPTORS
WO2010073078A3 (en) Heterocyclic compounds as hdac inhibitors
WO2011037833A3 (en) Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents
WO2010068520A3 (en) Substituted imidazoheterocycle derivatives
IL201795A0 (en) Stereoisomers propofol therapeutic compounds

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07705622

Country of ref document: EP

Kind code of ref document: A2