WO2007091919A8 - Method for treating chronic illnesses (variants), method for producing a biograft (variants) and a biograft (variants) - Google Patents

Method for treating chronic illnesses (variants), method for producing a biograft (variants) and a biograft (variants)

Info

Publication number
WO2007091919A8
WO2007091919A8 PCT/RU2007/000013 RU2007000013W WO2007091919A8 WO 2007091919 A8 WO2007091919 A8 WO 2007091919A8 RU 2007000013 W RU2007000013 W RU 2007000013W WO 2007091919 A8 WO2007091919 A8 WO 2007091919A8
Authority
WO
WIPO (PCT)
Prior art keywords
variants
biograft
chronic illnesses
treating chronic
cells
Prior art date
Application number
PCT/RU2007/000013
Other languages
French (fr)
Russian (ru)
Other versions
WO2007091919A1 (en
Inventor
Valeriy Ivanovich Shumakov
Nina Andreyevna Onischenko
Sergey Vasilyevich Gureev
Andrey Aleksandrovich Temnov
Original Assignee
Federalnoye G Uchrezhdeniye Ni
Valeriy Ivanovich Shumakov
Nina Andreyevna Onischenko
Sergey Vasilyevich Gureev
Andrey Aleksandrovich Temnov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Federalnoye G Uchrezhdeniye Ni, Valeriy Ivanovich Shumakov, Nina Andreyevna Onischenko, Sergey Vasilyevich Gureev, Andrey Aleksandrovich Temnov filed Critical Federalnoye G Uchrezhdeniye Ni
Publication of WO2007091919A1 publication Critical patent/WO2007091919A1/en
Publication of WO2007091919A8 publication Critical patent/WO2007091919A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46434—Antigens related to induction of tolerance to non-self
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention relates to medicine and can be used for treating chronic illnesses. The aim of said invention is to increase the regeneration potential of autologous mononuclear cells, thereby increasing the efficiency of treatment of a large range of chronic illnesses. The inventive method for treating chronic illnesses consists in sampling a patient cell material for subsequently separating the autologous mononuclear cells therefrom, cultivating the mononuclear autologic cells for obtaining a biograf and subsequently transplanting said biograf to the patient, wherein the cultivation is carried out by adding a tissue-specific antigen which corresponds to the injured member or to the separated autologous mononuclear cells, prior to the cultivation, lymphoid and/or dendrite cells, which are pre-cultivated by addition of the tissue-specific antigen corresponding the injured member, are added. The methods for obtaining the biograft and the biograft obtained by said method are also disclosed.
PCT/RU2007/000013 2006-02-09 2007-01-15 Method for treating chronic illnesses (variants), method for producing a biograft (variants) and a biograft (variants) WO2007091919A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2006103865/14A RU2322248C2 (en) 2006-02-09 2006-02-09 Method for treating chronic diseases (variants), method for obtaining a biotransplant (variants), a biotransplant (variants)
RU2006103865 2006-02-09

Publications (2)

Publication Number Publication Date
WO2007091919A1 WO2007091919A1 (en) 2007-08-16
WO2007091919A8 true WO2007091919A8 (en) 2007-12-06

Family

ID=38345426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2007/000013 WO2007091919A1 (en) 2006-02-09 2007-01-15 Method for treating chronic illnesses (variants), method for producing a biograft (variants) and a biograft (variants)

Country Status (2)

Country Link
RU (1) RU2322248C2 (en)
WO (1) WO2007091919A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2925218B1 (en) * 2007-12-13 2010-03-12 Photonis France IMAGE INTENSIFIER TUBE WITH REDUCED SIZE AND NIGHT VISION SYSTEM EQUIPPED WITH SUCH A TUBE
RU2488356C1 (en) * 2012-02-28 2013-07-27 Федеральное государственное бюджетное учреждение "Научный центр реконструктивной и восстановительной хирургии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НЦРВХ" СО РАМН) Method of correcting immune disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2089204C1 (en) * 1994-11-24 1997-09-10 Научно-производственное объединение "Иммунопрепарат" Method of preparing peptides recovering the prostate gland function
RU2268061C1 (en) * 2004-06-04 2006-01-20 ЗАО "РеМеТэкс" Biotransplant, method for its obtaining (variants) and method for treating ischemic cardiac disease

Also Published As

Publication number Publication date
WO2007091919A1 (en) 2007-08-16
RU2006103865A (en) 2007-08-20
RU2322248C2 (en) 2008-04-20

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