WO2007091039A2 - Production of cabergoline and novel polymorphic form thereof - Google Patents
Production of cabergoline and novel polymorphic form thereof Download PDFInfo
- Publication number
- WO2007091039A2 WO2007091039A2 PCT/GB2007/000397 GB2007000397W WO2007091039A2 WO 2007091039 A2 WO2007091039 A2 WO 2007091039A2 GB 2007000397 W GB2007000397 W GB 2007000397W WO 2007091039 A2 WO2007091039 A2 WO 2007091039A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cabergoline
- tame
- solvent
- methyl ether
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07705129A EP2007761A2 (en) | 2006-02-08 | 2007-02-06 | Production of cabergoline and novel polymorphic form thereof |
AU2007213571A AU2007213571A1 (en) | 2006-02-08 | 2007-02-06 | Production of cabergoline and novel polymorphic form thereof |
CA002640081A CA2640081A1 (en) | 2006-02-08 | 2007-02-06 | Production of cabergoline and novel polymorphic form thereof |
JP2008553820A JP2009526030A (en) | 2006-02-08 | 2007-02-06 | CABERGOLINE AND METHOD FOR PRODUCING NOVEL POLYMORPHIM FORM |
BRPI0707161-2A BRPI0707161A2 (en) | 2006-02-08 | 2007-02-06 | cabergoline production and its new polymorphic forms |
IL192870A IL192870A0 (en) | 2006-02-08 | 2008-07-17 | A polymorphic form of cabergoline and methods for the production thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0602557.1A GB0602557D0 (en) | 2006-02-08 | 2006-02-08 | Production of cabergoline and novel polymorphic form thereof |
GB0602557.1 | 2006-02-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2007091039A2 true WO2007091039A2 (en) | 2007-08-16 |
WO2007091039A3 WO2007091039A3 (en) | 2007-10-18 |
WO2007091039A8 WO2007091039A8 (en) | 2008-11-13 |
Family
ID=36119736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2007/000397 WO2007091039A2 (en) | 2006-02-08 | 2007-02-06 | Production of cabergoline and novel polymorphic form thereof |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2007761A2 (en) |
JP (1) | JP2009526030A (en) |
CN (1) | CN101384589A (en) |
AU (1) | AU2007213571A1 (en) |
BR (1) | BRPI0707161A2 (en) |
CA (1) | CA2640081A1 (en) |
GB (1) | GB0602557D0 (en) |
IL (1) | IL192870A0 (en) |
WO (1) | WO2007091039A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7531551B2 (en) | 2003-05-08 | 2009-05-12 | Ivax Pharmaceuticals S.R.O. | Polymorphs of cabergoline |
US7939665B2 (en) * | 2007-05-04 | 2011-05-10 | Apotex Pharmachem Inc. | Efficient process for the preparation of cabergoline and its intermediates |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4526892A (en) * | 1981-03-03 | 1985-07-02 | Farmitalia Carlo Erba, S.P.A. | Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas |
WO2002085902A1 (en) * | 2001-04-16 | 2002-10-31 | Finetech Laboratories Ltd. | Process and intermediates for production of cabergoline and related compounds |
IL155545A (en) * | 2003-04-21 | 2009-12-24 | Finetech Pharmaceutical Ltd | Solvate form of cabergoline |
CA2525104A1 (en) * | 2003-05-08 | 2004-11-25 | Ivax Pharmaceuticals S.R.O. | Polymorphs of cabergoline |
-
2006
- 2006-02-08 GB GBGB0602557.1A patent/GB0602557D0/en not_active Ceased
-
2007
- 2007-02-06 CA CA002640081A patent/CA2640081A1/en not_active Abandoned
- 2007-02-06 EP EP07705129A patent/EP2007761A2/en not_active Withdrawn
- 2007-02-06 CN CNA2007800047542A patent/CN101384589A/en active Pending
- 2007-02-06 BR BRPI0707161-2A patent/BRPI0707161A2/en not_active IP Right Cessation
- 2007-02-06 AU AU2007213571A patent/AU2007213571A1/en not_active Abandoned
- 2007-02-06 WO PCT/GB2007/000397 patent/WO2007091039A2/en active Application Filing
- 2007-02-06 JP JP2008553820A patent/JP2009526030A/en active Pending
-
2008
- 2008-07-17 IL IL192870A patent/IL192870A0/en unknown
Non-Patent Citations (1)
Title |
---|
None |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7531551B2 (en) | 2003-05-08 | 2009-05-12 | Ivax Pharmaceuticals S.R.O. | Polymorphs of cabergoline |
US7939665B2 (en) * | 2007-05-04 | 2011-05-10 | Apotex Pharmachem Inc. | Efficient process for the preparation of cabergoline and its intermediates |
Also Published As
Publication number | Publication date |
---|---|
AU2007213571A1 (en) | 2007-08-16 |
BRPI0707161A2 (en) | 2011-04-26 |
IL192870A0 (en) | 2009-02-11 |
EP2007761A2 (en) | 2008-12-31 |
CN101384589A (en) | 2009-03-11 |
CA2640081A1 (en) | 2007-08-16 |
GB0602557D0 (en) | 2006-03-22 |
WO2007091039A8 (en) | 2008-11-13 |
WO2007091039A3 (en) | 2007-10-18 |
JP2009526030A (en) | 2009-07-16 |
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SPECIFICATION | PREPARATION OF ODANACATIB AND ITS INTERMEDIATES |
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