WO2007084157A3 - Promédicaments nucléosidiques pour le traitement d'infections virales - Google Patents

Promédicaments nucléosidiques pour le traitement d'infections virales Download PDF

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Publication number
WO2007084157A3
WO2007084157A3 PCT/US2006/010816 US2006010816W WO2007084157A3 WO 2007084157 A3 WO2007084157 A3 WO 2007084157A3 US 2006010816 W US2006010816 W US 2006010816W WO 2007084157 A3 WO2007084157 A3 WO 2007084157A3
Authority
WO
WIPO (PCT)
Prior art keywords
viral infections
treating viral
nucleoside prodrugs
nucleoside
prodrugs
Prior art date
Application number
PCT/US2006/010816
Other languages
English (en)
Other versions
WO2007084157A2 (fr
Inventor
Christopher Don Roberts
Jesse D Keicher
Natalia B Dyatkina
Original Assignee
Genelabs Tech Inc
Christopher Don Roberts
Jesse D Keicher
Natalia B Dyatkina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genelabs Tech Inc, Christopher Don Roberts, Jesse D Keicher, Natalia B Dyatkina filed Critical Genelabs Tech Inc
Publication of WO2007084157A2 publication Critical patent/WO2007084157A2/fr
Publication of WO2007084157A3 publication Critical patent/WO2007084157A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne des composés de promédicaments, des compositions et des méthodes pour le traitement d'infections virales causées par un virus de la famille des flaviviridae tel que le virus de l'hépatite C.
PCT/US2006/010816 2005-03-23 2006-03-23 Promédicaments nucléosidiques pour le traitement d'infections virales WO2007084157A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66489705P 2005-03-23 2005-03-23
US60/664,897 2005-03-23

Publications (2)

Publication Number Publication Date
WO2007084157A2 WO2007084157A2 (fr) 2007-07-26
WO2007084157A3 true WO2007084157A3 (fr) 2007-11-08

Family

ID=38288057

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/010816 WO2007084157A2 (fr) 2005-03-23 2006-03-23 Promédicaments nucléosidiques pour le traitement d'infections virales

Country Status (1)

Country Link
WO (1) WO2007084157A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
CA3186054A1 (fr) 2020-08-07 2022-02-10 Daniel H. BYUN Promedicaments d'analogues nucleotidiques de phosphonamide et leur utilisation pharmaceutique

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057425A2 (fr) * 2001-01-22 2002-07-25 Merck & Co., Inc. Derives de nucleoside comme inhibiteurs de l'arn polymerase virale arn-dependante
WO2003061576A2 (fr) * 2002-01-17 2003-07-31 Ribapharm Inc. Analogues de nucleosides de deazapurine et utilisation de ceux-ci en tant qu'agents therapeutiques
WO2004028481A2 (fr) * 2002-09-30 2004-04-08 Genelabs Technologies, Inc. Derives nucleosidiques servant au traitement d'une infection par le virus de l'hepatite c
WO2005042556A1 (fr) * 2003-10-27 2005-05-12 Genelabs Technologies, Inc. Composes nucleosides permettant de traiter des infections virales
WO2005044835A1 (fr) * 2003-10-27 2005-05-19 Genelabs Technologies, Inc. Procedes de preparation de derives 7-(2'-$g(b)-d-ribofuranosyl substitue)-4-(nr2r3)-5-(ethyn-1-yl substitue)-pyrrolo[2,3-d]pyrimidine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057425A2 (fr) * 2001-01-22 2002-07-25 Merck & Co., Inc. Derives de nucleoside comme inhibiteurs de l'arn polymerase virale arn-dependante
WO2003061576A2 (fr) * 2002-01-17 2003-07-31 Ribapharm Inc. Analogues de nucleosides de deazapurine et utilisation de ceux-ci en tant qu'agents therapeutiques
WO2004028481A2 (fr) * 2002-09-30 2004-04-08 Genelabs Technologies, Inc. Derives nucleosidiques servant au traitement d'une infection par le virus de l'hepatite c
WO2005042556A1 (fr) * 2003-10-27 2005-05-12 Genelabs Technologies, Inc. Composes nucleosides permettant de traiter des infections virales
WO2005044835A1 (fr) * 2003-10-27 2005-05-19 Genelabs Technologies, Inc. Procedes de preparation de derives 7-(2'-$g(b)-d-ribofuranosyl substitue)-4-(nr2r3)-5-(ethyn-1-yl substitue)-pyrrolo[2,3-d]pyrimidine

Also Published As

Publication number Publication date
WO2007084157A2 (fr) 2007-07-26

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