WO2007080470A3 - A method for the purification of levetiracetam - Google Patents

A method for the purification of levetiracetam Download PDF

Info

Publication number
WO2007080470A3
WO2007080470A3 PCT/IB2007/000029 IB2007000029W WO2007080470A3 WO 2007080470 A3 WO2007080470 A3 WO 2007080470A3 IB 2007000029 W IB2007000029 W IB 2007000029W WO 2007080470 A3 WO2007080470 A3 WO 2007080470A3
Authority
WO
WIPO (PCT)
Prior art keywords
levetiracetam
purification
relates
present
formula
Prior art date
Application number
PCT/IB2007/000029
Other languages
French (fr)
Other versions
WO2007080470A2 (en
Inventor
Siripragada Mahender Rao
Kunchithapatham Thirumurugan
Kundrappu Chinnam Naidu
Original Assignee
Orchid Chemicals & Pharm Ltd
Siripragada Mahender Rao
Kunchithapatham Thirumurugan
Kundrappu Chinnam Naidu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals & Pharm Ltd, Siripragada Mahender Rao, Kunchithapatham Thirumurugan, Kundrappu Chinnam Naidu filed Critical Orchid Chemicals & Pharm Ltd
Publication of WO2007080470A2 publication Critical patent/WO2007080470A2/en
Publication of WO2007080470A3 publication Critical patent/WO2007080470A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones

Abstract

The present invention relates to an improved process for the preparation of Levetiracetam of formula (I). More particularly, the present invention relates to a method for the purification of crude Levetiracetam using a solvent mixture of ethyl acetate and water.(I).
PCT/IB2007/000029 2006-01-16 2007-01-08 A method for the purification of levetiracetam WO2007080470A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN60/CHE/2006 2006-01-16
IN60CH2006 2006-01-16

Publications (2)

Publication Number Publication Date
WO2007080470A2 WO2007080470A2 (en) 2007-07-19
WO2007080470A3 true WO2007080470A3 (en) 2007-12-13

Family

ID=38256674

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000029 WO2007080470A2 (en) 2006-01-16 2007-01-08 A method for the purification of levetiracetam

Country Status (1)

Country Link
WO (1) WO2007080470A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009057137A2 (en) * 2007-08-22 2009-05-07 Alembic Limited A process for the purification of levetiracetam
CN103922988A (en) * 2014-04-29 2014-07-16 苏州天马精细化学品股份有限公司 Method for purifying levetiracetam crude product
CN108329247A (en) * 2018-02-10 2018-07-27 浙江华海药业股份有限公司 A kind of preparation method of small particle size Levetiracetam
CN114560800A (en) * 2022-03-03 2022-05-31 吉林省博大制药股份有限公司 Production method of levetiracetam bulk drug

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005023763A1 (en) * 2003-09-05 2005-03-17 Ranbaxy Laboratories Limited Process for the preparation of pure levetiracetam

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005023763A1 (en) * 2003-09-05 2005-03-17 Ranbaxy Laboratories Limited Process for the preparation of pure levetiracetam

Also Published As

Publication number Publication date
WO2007080470A2 (en) 2007-07-19

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DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
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