WO2007080427A3 - Procédé de fabrication de micro-aiguilles - Google Patents

Procédé de fabrication de micro-aiguilles Download PDF

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Publication number
WO2007080427A3
WO2007080427A3 PCT/GB2007/000117 GB2007000117W WO2007080427A3 WO 2007080427 A3 WO2007080427 A3 WO 2007080427A3 GB 2007000117 W GB2007000117 W GB 2007000117W WO 2007080427 A3 WO2007080427 A3 WO 2007080427A3
Authority
WO
WIPO (PCT)
Prior art keywords
array
microneedles
providing
making microneedles
cavities
Prior art date
Application number
PCT/GB2007/000117
Other languages
English (en)
Other versions
WO2007080427A2 (fr
Inventor
Andrew James Kirby
Original Assignee
Functional Microstructures Ltd
Andrew James Kirby
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Functional Microstructures Ltd, Andrew James Kirby filed Critical Functional Microstructures Ltd
Publication of WO2007080427A2 publication Critical patent/WO2007080427A2/fr
Publication of WO2007080427A3 publication Critical patent/WO2007080427A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00—Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/02—Surface shaping of articles, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing
    • B29C59/026—Surface shaping of articles, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing of layered or coated substantially flat surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C99/00—Subject matter not provided for in other groups of this subclass
    • B81C99/0075—Manufacture of substrate-free structures
    • B81C99/0085—Manufacture of substrate-free structures using moulds and master templates, e.g. for hot-embossing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/0827—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using UV radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7544—Injection needles, syringes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/756—Microarticles, nanoarticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0361—Tips, pillars

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention porte sur un procédé de formation d’un réseau de micro-aiguilles solides, le procédé comprenant : (i) fournir un moule (1) possédant un réseau de cavités (2a, 2b, 2c) pour la formation de micro-aiguilles ; (ii) fournir un substrat (5) sur lequel le réseau de micro-aiguilles devra être constitué ; (iii) conférer au réseau de cavités une substance (4) à partir de laquelle un réseau de micro-aiguilles solides peut être constitué ; et (iv) constituer le réseau de micro-aiguilles solides (7a, 7b, 7c) sur le substrat à partir de la substance.
PCT/GB2007/000117 2006-01-16 2007-01-16 Procédé de fabrication de micro-aiguilles WO2007080427A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0600795A GB0600795D0 (en) 2006-01-16 2006-01-16 Method of making microneedles
GB0600795.9 2006-01-16

Publications (2)

Publication Number Publication Date
WO2007080427A2 WO2007080427A2 (fr) 2007-07-19
WO2007080427A3 true WO2007080427A3 (fr) 2007-09-07

Family

ID=35998088

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/000117 WO2007080427A2 (fr) 2006-01-16 2007-01-16 Procédé de fabrication de micro-aiguilles

Country Status (2)

Country Link
GB (1) GB0600795D0 (fr)
WO (1) WO2007080427A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
US9220678B2 (en) 2007-12-24 2015-12-29 The University Of Queensland Coating method
CA2749347C (fr) 2008-02-07 2018-03-27 The University Of Queensland Fabrication de timbre transdermique
AU2009250341A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection using a needle projection patch
KR100938631B1 (ko) * 2008-06-18 2010-01-22 주식회사 누리엠웰니스 솔리드 마이크로구조체의 제조방법
AU2009329806A1 (en) * 2008-12-22 2010-07-01 The University Of Queensland Patch production
US9289925B2 (en) 2009-04-10 2016-03-22 3M Innovative Properties Company Methods of making hollow microneedle arrays and articles and uses therefrom
JP5542404B2 (ja) * 2009-10-08 2014-07-09 東レエンジニアリング株式会社 マイクロニードルスタンパーの製造方法
JP5558772B2 (ja) * 2009-10-08 2014-07-23 東レエンジニアリング株式会社 マイクロニードルシートのスタンパー及びその製造方法とそれを用いたマイクロニードルの製造方法
WO2012006677A1 (fr) 2010-07-14 2012-01-19 The University Of Queensland Appareil d'application de timbre transdermique
EP3881781B1 (fr) 2011-10-12 2023-03-29 Vaxxas Pty Limited Dispositif de distribution
AU2016214968B2 (en) 2015-02-02 2021-02-25 Vaxxas Pty Limited Microprojection array applicator and method
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
GB201517373D0 (en) 2015-10-01 2015-11-18 Ge Healthcare Uk Ltd Micro-Needle Sampling Device And Use Thereof
KR101747099B1 (ko) * 2016-02-11 2017-06-14 권영덕 생체적합성 고분자를 이용한 마이크로니들의 제조방법
JP2018015322A (ja) * 2016-07-28 2018-02-01 富士フイルム株式会社 経皮吸収シートの製造方法
ES2960937T3 (es) 2017-03-31 2024-03-07 Vaxxas Pty Ltd Dispositivo y método para recubrir superficies
WO2018227246A1 (fr) 2017-06-13 2018-12-20 Vaxxas Pty Limited Contrôle de la qualité de revêtements de substrats
CA3071680A1 (fr) 2017-08-04 2019-02-07 Vaxxas Pty Limited Actionneur a stockage d'energie mecanique eleve compact et a force de declenchement faible pour l'administration de patchs a reseaux de microprojections (prm)
WO2019221318A1 (fr) * 2018-05-18 2019-11-21 포항공과대학교 산학협력단 Timbre transdermique de diffusion de médicament et son procédé de préparation
GB2607115B (en) * 2021-06-25 2023-10-04 Cipherx Tech Ltd Method of producing a microneedle array

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064193A2 (fr) * 2000-12-14 2002-08-22 Georgia Tech Research Corporation Appareils a microaiguilles et fabrication
WO2004062899A2 (fr) * 2003-01-16 2004-07-29 Seung-Seob Lee Procede de fabrication d'un reseau de micro-aiguille polymere a l'aide d'un procede liga
WO2005038862A2 (fr) * 2003-07-07 2005-04-28 10X Technology Llc. Procede et dispositif pour produire des microstructures precises, et moules polymeres pour les realiser

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064193A2 (fr) * 2000-12-14 2002-08-22 Georgia Tech Research Corporation Appareils a microaiguilles et fabrication
WO2004062899A2 (fr) * 2003-01-16 2004-07-29 Seung-Seob Lee Procede de fabrication d'un reseau de micro-aiguille polymere a l'aide d'un procede liga
WO2005038862A2 (fr) * 2003-07-07 2005-04-28 10X Technology Llc. Procede et dispositif pour produire des microstructures precises, et moules polymeres pour les realiser

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MC ALLISTER D V ET AL: "Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 100, no. 24, 25 November 2003 (2003-11-25), pages 13755 - 13760, XP002329900, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2007080427A2 (fr) 2007-07-19
GB0600795D0 (en) 2006-02-22

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