WO2007063509A3 - Phosphocreatine complexes - Google Patents
Phosphocreatine complexes Download PDFInfo
- Publication number
- WO2007063509A3 WO2007063509A3 PCT/IB2006/054515 IB2006054515W WO2007063509A3 WO 2007063509 A3 WO2007063509 A3 WO 2007063509A3 IB 2006054515 W IB2006054515 W IB 2006054515W WO 2007063509 A3 WO2007063509 A3 WO 2007063509A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- complexes
- phosphocreatine
- diseases
- novel
- fall
- Prior art date
Links
- CFPWPNDPUSLDPF-UHFFFAOYSA-N 2-[carbamimidoyl(methyl)amino]-2-phosphonoacetic acid Chemical class NC(=N)N(C)C(C(O)=O)P(O)(O)=O CFPWPNDPUSLDPF-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001449 anionic compounds Chemical class 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910001412 inorganic anion Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002891 organic anions Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/222—Amides of phosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to novel phosphocreatine complexes useful for the treatment of diseases of the central nervous system, having the following general formula (I): wherein M is a metal, preferably Mg, and An- is an organic or inorganic anion. The pharmaceutically acceptable salts of such complexes also fall within the scope of the invention.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000847A ITTO20050847A1 (en) | 2005-11-30 | 2005-11-30 | COMPLEXES OF PHOSPHOCREATIN |
ITTO2005A000847 | 2005-11-30 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2007063509A2 WO2007063509A2 (en) | 2007-06-07 |
WO2007063509A8 WO2007063509A8 (en) | 2007-09-07 |
WO2007063509A3 true WO2007063509A3 (en) | 2007-10-18 |
Family
ID=38092648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2006/054515 WO2007063509A2 (en) | 2005-11-30 | 2006-11-29 | Phosphocreatine complexes |
Country Status (2)
Country | Link |
---|---|
IT (1) | ITTO20050847A1 (en) |
WO (1) | WO2007063509A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140044690A1 (en) * | 2012-08-08 | 2014-02-13 | University Of South Florida | High-Energy Compounds for Use in Alzheimer's and Other Neurodegenerative Diseases |
CN111777636B (en) * | 2020-07-09 | 2023-06-16 | 山东罗欣药业集团股份有限公司 | Preparation method of medicine for myocardial protection |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3539625A (en) * | 1966-04-08 | 1970-11-10 | Ugine Kuhlmann | Phosphocreatine salts |
WO2002022135A1 (en) * | 2000-09-14 | 2002-03-21 | Board Of Regents Of The University Of Nebraska | Creatine ester pronutrient compounds and formulations |
CN1709896A (en) * | 2005-07-10 | 2005-12-21 | 杨喜鸿 | Magnesium salt of creatine phosphate, its preparation and use in pharmaceutical process |
CN1729988A (en) * | 2005-08-05 | 2006-02-08 | 杨喜鸿 | Composite medicine of creatine phosphate sodium and magnesium salt |
-
2005
- 2005-11-30 IT IT000847A patent/ITTO20050847A1/en unknown
-
2006
- 2006-11-29 WO PCT/IB2006/054515 patent/WO2007063509A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3539625A (en) * | 1966-04-08 | 1970-11-10 | Ugine Kuhlmann | Phosphocreatine salts |
WO2002022135A1 (en) * | 2000-09-14 | 2002-03-21 | Board Of Regents Of The University Of Nebraska | Creatine ester pronutrient compounds and formulations |
CN1709896A (en) * | 2005-07-10 | 2005-12-21 | 杨喜鸿 | Magnesium salt of creatine phosphate, its preparation and use in pharmaceutical process |
CN1729988A (en) * | 2005-08-05 | 2006-02-08 | 杨喜鸿 | Composite medicine of creatine phosphate sodium and magnesium salt |
Non-Patent Citations (4)
Title |
---|
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; YANG, XIHONG: "Magnesium (sodium/potassium) salt of phosphocreatine, its preparation and application in pharmacy", XP002441405, retrieved from STN Database accession no. 2006:1073081 * |
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; YANG, XIHONG: "Medicine composition containing sodium creatine phosphate and magnesium salt", XP002441406, retrieved from STN Database accession no. 2006:345051 * |
DE MORAES SILVA ET AL: "Potentiometric and spectroscopic study of mixed copper(II) complexes with amino acids and either adenosine 5? triphosphate or phosphocreatine", POLYHEDRON, vol. 25, 2006, pages 1319 - 1326, XP002441400 * |
LUNARDI, G. ET AL: "The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds", NEUROSCIENCE (SAN DIEGO, CA, UNITED STATES) , 142(4), 991-997 CODEN: NRSCDN; ISSN: 0306-4522, 2006, XP005839640 * |
Also Published As
Publication number | Publication date |
---|---|
ITTO20050847A1 (en) | 2007-06-01 |
WO2007063509A8 (en) | 2007-09-07 |
WO2007063509A2 (en) | 2007-06-07 |
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