WO2007046484A8 - Electrophoretic chip, electrophoretic device, and electrophoretic system - Google Patents

Electrophoretic chip, electrophoretic device, and electrophoretic system

Info

Publication number
WO2007046484A8
WO2007046484A8 PCT/JP2006/320878 JP2006320878W WO2007046484A8 WO 2007046484 A8 WO2007046484 A8 WO 2007046484A8 JP 2006320878 W JP2006320878 W JP 2006320878W WO 2007046484 A8 WO2007046484 A8 WO 2007046484A8
Authority
WO
WIPO (PCT)
Prior art keywords
electrophoretic
migration
dielectric substance
lanes
dielectrically
Prior art date
Application number
PCT/JP2006/320878
Other languages
French (fr)
Japanese (ja)
Other versions
WO2007046484A1 (en
Inventor
Osamu Teranuma
Mayuko Sakamoto
Yoshihiro Izumi
Masayuki Fujimoto
Original Assignee
Sharp Kk
Univ Shizuoka Nat Univ Corp
Osamu Teranuma
Mayuko Sakamoto
Yoshihiro Izumi
Masayuki Fujimoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sharp Kk, Univ Shizuoka Nat Univ Corp, Osamu Teranuma, Mayuko Sakamoto, Yoshihiro Izumi, Masayuki Fujimoto filed Critical Sharp Kk
Publication of WO2007046484A1 publication Critical patent/WO2007046484A1/en
Publication of WO2007046484A8 publication Critical patent/WO2007046484A8/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/028—Non-uniform field separators using travelling electric fields, i.e. travelling wave dielectrophoresis [TWD]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0424—Dielectrophoretic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Electrostatic Separation (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

An electrophoretic panel (10) causes a dielectric substance to migrate dielectrically by applying an electric field generated by an AC voltage, to a sample containing the dielectric substance. The electrophoretic panel (10) is equipped, on a lower substrate (1), with a plurality of migration lanes (3) for causing the dielectric substance to migrate dielectrically. On the lower substrate (1), there is disposed a migration electrode array (6), which includes a plurality of migration electrodes (6a) intersecting with the migration lanes (3) and which causes the dielectric substance to migrate dielectrically by applying the AC voltage so as to apply the electric field to the sample injected into the migration lanes (3). The individual migration electrodes (6a) in the migration electrode array (6) are disposed across the migration lanes (3).
PCT/JP2006/320878 2005-10-19 2006-10-19 Electrophoretic chip, electrophoretic device, and electrophoretic system WO2007046484A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005-305047 2005-10-19
JP2005305047 2005-10-19

Publications (2)

Publication Number Publication Date
WO2007046484A1 WO2007046484A1 (en) 2007-04-26
WO2007046484A8 true WO2007046484A8 (en) 2007-07-05

Family

ID=37962577

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2006/320878 WO2007046484A1 (en) 2005-10-19 2006-10-19 Electrophoretic chip, electrophoretic device, and electrophoretic system

Country Status (1)

Country Link
WO (1) WO2007046484A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7012088B2 (en) 2016-10-18 2022-01-27 メナリーニ・シリコン・バイオシステムズ・ソシエタ・ペル・アチオニ Electronic drive circuit for driving electrodes of microfluidic device for particle manipulation and corresponding analytical equipment
JP7028424B2 (en) 2015-10-07 2022-03-02 株式会社Ａｆｉテクノロジー Inspection equipment and inspection system

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008284626A (en) * 2007-05-16 2008-11-27 Miraial Kk Micro-flow channel device
US8864972B2 (en) 2007-10-05 2014-10-21 Kyushu Institute Of Technology Dielectrophoresis apparatus and method
JP2023005958A (en) * 2021-06-30 2023-01-18 株式会社Ｓｃｒｅｅｎホールディングス Flow passage chip and dielectrophoretic device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4127405C2 (en) * 1991-08-19 1996-02-29 Fraunhofer Ges Forschung Process for the separation of mixtures of microscopic dielectric particles suspended in a liquid or a gel and device for carrying out the process
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
GB9208357D0 (en) * 1992-04-16 1992-06-03 British Tech Group Apparatus for separating a mixture
GB9615775D0 (en) * 1996-07-26 1996-09-04 British Tech Group Apparatus and method for characterising particles using dielectrophoresis
IT1309430B1 (en) * 1999-05-18 2002-01-23 Guerrieri Roberto METHOD AND APPARATUS FOR HANDLING PARTICLES BY MEANS OF ELECTROPHORESIS
GB9916848D0 (en) * 1999-07-20 1999-09-22 Univ Wales Bangor Travelling wave dielectrophoretic apparatus and method
CN100494360C (en) * 2001-03-22 2009-06-03 博奥生物有限公司 Process for separating cells and its application

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7028424B2 (en) 2015-10-07 2022-03-02 株式会社Ａｆｉテクノロジー Inspection equipment and inspection system
JP7012088B2 (en) 2016-10-18 2022-01-27 メナリーニ・シリコン・バイオシステムズ・ソシエタ・ペル・アチオニ Electronic drive circuit for driving electrodes of microfluidic device for particle manipulation and corresponding analytical equipment

Also Published As

Publication number Publication date
WO2007046484A1 (en) 2007-04-26

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