WO2007038501A3 - Rheumatoid arthritis markers - Google Patents

Rheumatoid arthritis markers Download PDF

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Publication number
WO2007038501A3
WO2007038501A3 PCT/US2006/037461 US2006037461W WO2007038501A3 WO 2007038501 A3 WO2007038501 A3 WO 2007038501A3 US 2006037461 W US2006037461 W US 2006037461W WO 2007038501 A3 WO2007038501 A3 WO 2007038501A3
Authority
WO
WIPO (PCT)
Prior art keywords
rheumatoid arthritis
subject
methods
arthritis markers
markers
Prior art date
Application number
PCT/US2006/037461
Other languages
French (fr)
Other versions
WO2007038501A2 (en
Inventor
Peter K Gregersen
Franak Batliwalla
Original Assignee
The Feinstein Inst Medical Res
Peter K Gregersen
Franak Batliwalla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Feinstein Inst Medical Res, Peter K Gregersen, Franak Batliwalla filed Critical The Feinstein Inst Medical Res
Publication of WO2007038501A2 publication Critical patent/WO2007038501A2/en
Publication of WO2007038501A3 publication Critical patent/WO2007038501A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Provided are methods of predicting responsiveness to TNF blockade therapy in a subject with rheumatoid arthritis (RA). Also provided are methods of determining the effectiveness of TNF blockade therapy in a subject with RA. Additionally, methods of diagnosis of RA in a subject and method of determining whether a subject is at risk for RA are provided.
PCT/US2006/037461 2005-09-27 2006-09-27 Rheumatoid arthritis markers WO2007038501A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72102605P 2005-09-27 2005-09-27
US60/721,026 2005-09-27

Publications (2)

Publication Number Publication Date
WO2007038501A2 WO2007038501A2 (en) 2007-04-05
WO2007038501A3 true WO2007038501A3 (en) 2007-11-15

Family

ID=37900388

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/037461 WO2007038501A2 (en) 2005-09-27 2006-09-27 Rheumatoid arthritis markers

Country Status (1)

Country Link
WO (1) WO2007038501A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008132176A2 (en) * 2007-04-27 2008-11-06 Universite Catholique De Louvain Method for evaluating the response of an individual to tnf blocking therapy
NZ581742A (en) * 2007-06-08 2012-09-28 Biogen Idec Inc Biomarkers for predicting anti-tnf responsiveness or non-responsiveness
CN101855367A (en) * 2007-11-14 2010-10-06 日立化成工业株式会社 Enhanced fc receptor-mediated tumor necrosis factor superfamily mrna expression in peripheral blood leukocytes in patients with rheumatoid arthritis
ES2335381B1 (en) * 2008-09-24 2011-02-28 Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron IN VITRO METHOD AND KIT FOR THE FORECAST OR PREDICTION OF THE RESPONSE PART OF PATIENTS WITH REUMATOID ARTHRITIS TO THE TREATMENT WITH BLOCKING AGENTS OF THE TNFALFA FACTOR.
CN107385034B (en) 2009-09-03 2021-08-17 弗·哈夫曼-拉罗切有限公司 Methods for treating, diagnosing and monitoring rheumatoid arthritis
MX2012009755A (en) 2010-02-26 2012-09-12 Novo Nordisk As Stable antibody containing compositions.
CA2793137A1 (en) * 2010-03-24 2011-09-29 Tc Land Expression Genes and genes combinations predictive of early response or non response of subjects suffering from inflammatory disease to cytokine targeting drugs (cytd)
WO2011147921A1 (en) 2010-05-28 2011-12-01 Novo Nordisk A/S Stable multi-dose compositions comprising an antibody and a preservative
EP2680884B1 (en) 2011-02-28 2018-01-17 F. Hoffmann-La Roche AG Biological markers and methods for predicting response to b-cell antagonists
KR20140124767A (en) 2012-02-10 2014-10-27 노보 노르디스크 에이/에스 Methods related to treatment of inflammatory diseases and disorders
EP2813850A1 (en) * 2013-06-10 2014-12-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting rheumatoid arthritis treatment response
JPWO2015083765A1 (en) * 2013-12-04 2017-03-16 国立大学法人大阪大学 A method for predicting and evaluating the therapeutic effect of rheumatoid arthritis by biological agents
DE112016003948T5 (en) 2015-08-31 2018-05-09 City Of Sapporo MOLECULAR METHODS FOR EVALUATING A UROTHIAL DISEASE

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009479A1 (en) * 2001-06-08 2004-01-15 Jay Wohlgemuth Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009479A1 (en) * 2001-06-08 2004-01-15 Jay Wohlgemuth Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases

Also Published As

Publication number Publication date
WO2007038501A2 (en) 2007-04-05

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