WO2007034280A3 - Composition and method for prevention of influenza - Google Patents

Composition and method for prevention of influenza Download PDF

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Publication number
WO2007034280A3
WO2007034280A3 PCT/IB2006/002566 IB2006002566W WO2007034280A3 WO 2007034280 A3 WO2007034280 A3 WO 2007034280A3 IB 2006002566 W IB2006002566 W IB 2006002566W WO 2007034280 A3 WO2007034280 A3 WO 2007034280A3
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WO
WIPO (PCT)
Prior art keywords
subjects
subject
methods
allergic
diagnosed
Prior art date
Application number
PCT/IB2006/002566
Other languages
French (fr)
Other versions
WO2007034280A2 (en
Inventor
Moshe Amihood Blay
Original Assignee
Moshe Amihood Blay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moshe Amihood Blay filed Critical Moshe Amihood Blay
Publication of WO2007034280A2 publication Critical patent/WO2007034280A2/en
Publication of WO2007034280A3 publication Critical patent/WO2007034280A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16211Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Novel compositions and methods for vaccinating a subject against influenza.. The compositions and methods are based on the use a vaccine that includes an antigen that is extracted from Streptococcus pneumonia. The methods are particularly useful for vaccination of subjects who do not have an increased risk of developing pneumonia, subjects who have 4 x 109 to 11 x 109 white blood cells in a liter of blood, subjects who are not immunocompromised, subject who have functional spleen, subjects who are allergic to inactivated virus-based influenza vaccine, subjects who are allergic to eggs, subjects who are diagnosed with a Guillain-Barré syndrome, subjects who do not have cancer, leukemia, lymphoma, or multiple myeloma, subjects who do not have HIV infection, subjects who are not diagnosed with cirrhosis of the liver, subjects who are not recipients of organ transplants or bone marrow transplants, subject who do not take medications that lower immunity, and subject that are less than 65 years old.
PCT/IB2006/002566 2005-09-19 2006-09-15 Composition and method for prevention of influenza WO2007034280A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71774205P 2005-09-19 2005-09-19
US60/717,742 2005-09-19
US83018406P 2006-07-12 2006-07-12
US60/830,184 2006-07-12

Publications (2)

Publication Number Publication Date
WO2007034280A2 WO2007034280A2 (en) 2007-03-29
WO2007034280A3 true WO2007034280A3 (en) 2007-08-30

Family

ID=37889171

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/002566 WO2007034280A2 (en) 2005-09-19 2006-09-15 Composition and method for prevention of influenza

Country Status (1)

Country Link
WO (1) WO2007034280A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6097388B2 (en) * 2012-07-10 2017-03-15 ネピアン ブルー マウンテンズ ローカル ヘルス ディストリクト Risk stratification in influenza

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287173A (en) * 1979-09-24 1981-09-01 Merck & Co., Inc. Vaccine for dental caries
US5855901A (en) * 1995-06-07 1999-01-05 Alberta Research Council Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287173A (en) * 1979-09-24 1981-09-01 Merck & Co., Inc. Vaccine for dental caries
US5855901A (en) * 1995-06-07 1999-01-05 Alberta Research Council Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NOWAK-WEGRZYN A.: "Serum Opsonic Activity in Infants with Sickle-Cell Disease Immunized with Pneumococcal Polysaccharide Protein Conjugate Vaccine", CLIN. AND DIAGN. LAB. IMMUNOL., vol. 7, September 2000 (2000-09-01), pages 788 - 793, XP055118493, DOI: doi:10.1128/CDLI.7.5.788-793.2000 *
SHAFINOORI S.: "Impact of Pneumococcal Conjugate vaccine and the Severity of Winter Influenza-Like Illnesses on Invasive Pneumococcal Infections in Children and Adults", THE PEDIATRIC INFECTIOUS DISEASES JOURNAL, vol. 24, January 2005 (2005-01-01), pages 10 - 16 *

Also Published As

Publication number Publication date
WO2007034280A2 (en) 2007-03-29

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