WO2007033353A2 - Compositions de liaison a des cibles chimiques - Google Patents

Compositions de liaison a des cibles chimiques Download PDF

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Publication number
WO2007033353A2
WO2007033353A2 PCT/US2006/035968 US2006035968W WO2007033353A2 WO 2007033353 A2 WO2007033353 A2 WO 2007033353A2 US 2006035968 W US2006035968 W US 2006035968W WO 2007033353 A2 WO2007033353 A2 WO 2007033353A2
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
binding
composition
glucose
concentration
Prior art date
Application number
PCT/US2006/035968
Other languages
English (en)
Other versions
WO2007033353A3 (fr
Inventor
George Y. Daniloff
Original Assignee
Therabit, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabit, Inc. filed Critical Therabit, Inc.
Publication of WO2007033353A2 publication Critical patent/WO2007033353A2/fr
Publication of WO2007033353A3 publication Critical patent/WO2007033353A3/fr
Priority to US12/047,076 priority Critical patent/US20080200434A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention a trait à des compositions et des procédés pour la modulation et la régulation de la concentration d'une cible chimique dans un organisme ou dans un écosystème. Dans un mode de réalisation, la concentration est régulée de sorte qu'elle soit maintenue en-dessous ou au-dessus d'un certain seuil, permettant ainsi d'éviter des effets toxiques ou nuisibles de la cible chimique. Les compositions de l'invention peuvent, par exemple, être implantées dans un organisme humain ou disposées dans un écosystème. Les compositions comportent des groupes fonctionnels de liaison qui se lient de manière réversible à un cible chimique dans l'organisme ou l'écosystème. La capacité de liaison et les constantes de liaison pour une cible chimique sont conçues de sorte que la composition maintienne la concentration de la cible chimique sensiblement dans une plage de concentration bénéfique.
PCT/US2006/035968 2005-09-14 2006-09-14 Compositions de liaison a des cibles chimiques WO2007033353A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/047,076 US20080200434A1 (en) 2006-09-14 2008-03-12 Chemical Target-Binding Compositions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59630005P 2005-09-14 2005-09-14
US60/596,300 2005-09-14

Publications (2)

Publication Number Publication Date
WO2007033353A2 true WO2007033353A2 (fr) 2007-03-22
WO2007033353A3 WO2007033353A3 (fr) 2007-10-11

Family

ID=37865594

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/035968 WO2007033353A2 (fr) 2005-09-14 2006-09-14 Compositions de liaison a des cibles chimiques

Country Status (1)

Country Link
WO (1) WO2007033353A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115209954A (zh) * 2020-03-09 2022-10-18 生物组织再生和修复公司 用于治疗呼吸系统病变的组合物
WO2023003845A1 (fr) * 2021-07-20 2023-01-26 Ut-Battelle, Llc Adhésif résistant à réticulation dynamique ayant une aptitude au recyclage

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
US20050095636A1 (en) * 2003-07-16 2005-05-05 Warner Benjamin P. Method and apparatus for detecting chemical binding

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
US20050095636A1 (en) * 2003-07-16 2005-05-05 Warner Benjamin P. Method and apparatus for detecting chemical binding

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115209954A (zh) * 2020-03-09 2022-10-18 生物组织再生和修复公司 用于治疗呼吸系统病变的组合物
CN115209954B (zh) * 2020-03-09 2024-04-30 生物组织再生和修复公司 用于治疗呼吸系统病变的组合物
WO2023003845A1 (fr) * 2021-07-20 2023-01-26 Ut-Battelle, Llc Adhésif résistant à réticulation dynamique ayant une aptitude au recyclage

Also Published As

Publication number Publication date
WO2007033353A3 (fr) 2007-10-11

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