WO2007028714A3 - Verfahren zur herstellung von 2-substituierten carbonsäuren - Google Patents

Verfahren zur herstellung von 2-substituierten carbonsäuren Download PDF

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Publication number
WO2007028714A3
WO2007028714A3 PCT/EP2006/065592 EP2006065592W WO2007028714A3 WO 2007028714 A3 WO2007028714 A3 WO 2007028714A3 EP 2006065592 W EP2006065592 W EP 2006065592W WO 2007028714 A3 WO2007028714 A3 WO 2007028714A3
Authority
WO
WIPO (PCT)
Prior art keywords
producing
carboxylic acids
tertiary butyl
substituted carboxylic
relates
Prior art date
Application number
PCT/EP2006/065592
Other languages
English (en)
French (fr)
Other versions
WO2007028714A2 (de
Inventor
Eike Johannes Bergner
Klaus Ebel
Original Assignee
Basf Ag
Eike Johannes Bergner
Klaus Ebel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Eike Johannes Bergner, Klaus Ebel filed Critical Basf Ag
Publication of WO2007028714A2 publication Critical patent/WO2007028714A2/de
Publication of WO2007028714A3 publication Critical patent/WO2007028714A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von in 2-Position substituierten tert.-Butylestern durch Alkylierung des entsprechenden tert.-Butylester- Enolate. Die Erfindung betrifft darüber hinaus ein Verfahren zur Herstellung der ent sprechenden freien Carbonsäuren durch saure Hydrolyse der genannten tert-Butylester sowie deren Umsetzung zu weiteren Carbonsäureestern.
PCT/EP2006/065592 2005-09-06 2006-08-23 Verfahren zur herstellung von 2-substituierten carbonsäuren WO2007028714A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005042458.9 2005-09-06
DE200510042458 DE102005042458A1 (de) 2005-09-06 2005-09-06 Verfahren zur Herstellung von 2-substituierten Carbonsäuren

Publications (2)

Publication Number Publication Date
WO2007028714A2 WO2007028714A2 (de) 2007-03-15
WO2007028714A3 true WO2007028714A3 (de) 2007-05-31

Family

ID=37775612

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/065592 WO2007028714A2 (de) 2005-09-06 2006-08-23 Verfahren zur herstellung von 2-substituierten carbonsäuren

Country Status (2)

Country Link
DE (1) DE102005042458A1 (de)
WO (1) WO2007028714A2 (de)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470845A (en) * 1992-10-28 1995-11-28 Bristol-Myers Squibb Company Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia
WO2001009079A1 (de) * 1999-07-29 2001-02-08 Speedel Pharma Ag 2-alkyl-5-halogen-pent-4-encarbonsäuren und deren herstellung

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470845A (en) * 1992-10-28 1995-11-28 Bristol-Myers Squibb Company Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia
WO2001009079A1 (de) * 1999-07-29 2001-02-08 Speedel Pharma Ag 2-alkyl-5-halogen-pent-4-encarbonsäuren und deren herstellung

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
ALCOCK ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 50, 1985, pages 3526 - 3535, XP002427825 *
BOOKSER ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, 2000, pages 1495 - 1507, XP002427824 *
CUVIGNY ET AL., ORGANOMETALLICS IN CHEMICAL SYNTHESIS, 1971, pages 237 - 247, XP002427822 *
HESTER ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. 44, 2001, pages 1099 - 1115, XP002427829 *
MILLIARD ET AL., JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 99:14, 1977, pages 4833 - 4835, XP002427823 *
SISIDO ET AL., JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 81, 1959, pages 5817 - 5819, XP002427821 *
STOERMER ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 61, 1996, pages 9115 - 9125, XP002427828 *
WINKLER ET AL., TETRAHEDRON LETTERS, vol. 30, no. 37, 1989, pages 4943 - 4946, XP002427826 *
WULFF ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 58, 1993, pages 2381 - 2393, XP002427827 *

Also Published As

Publication number Publication date
WO2007028714A2 (de) 2007-03-15
DE102005042458A1 (de) 2007-03-22

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