WO2007017646A3 - Anti-malarial composition comprising artesunate and lumefantrine - Google Patents

Anti-malarial composition comprising artesunate and lumefantrine Download PDF

Info

Publication number
WO2007017646A3
WO2007017646A3 PCT/GB2006/002919 GB2006002919W WO2007017646A3 WO 2007017646 A3 WO2007017646 A3 WO 2007017646A3 GB 2006002919 W GB2006002919 W GB 2006002919W WO 2007017646 A3 WO2007017646 A3 WO 2007017646A3
Authority
WO
WIPO (PCT)
Prior art keywords
lumefantrine
artesunate
composition
malarial composition
malarial
Prior art date
Application number
PCT/GB2006/002919
Other languages
French (fr)
Other versions
WO2007017646A2 (en
Inventor
Amar Lulla
Geena Malhotra
Original Assignee
Cipla Ltd
Curtis Philip Anthony
Amar Lulla
Geena Malhotra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd, Curtis Philip Anthony, Amar Lulla, Geena Malhotra filed Critical Cipla Ltd
Publication of WO2007017646A2 publication Critical patent/WO2007017646A2/en
Publication of WO2007017646A3 publication Critical patent/WO2007017646A3/en
Priority to GB0804039A priority Critical patent/GB2443377A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

A pharmaceutical composition comprising artesunate and lumefantrine provided in combination in a single pharmaceutical dosage unit. The invention also relates to a method of making the pharmaceutical composition, and to the use of the composition in the treatment of malaria.
PCT/GB2006/002919 2005-08-05 2006-08-04 Anti-malarial composition comprising artesunate and lumefantrine WO2007017646A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0804039A GB2443377A (en) 2005-08-05 2008-03-04 Anti-malarial composition comprising artesunate and lumefantrine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN794/MUM/2005 2005-08-05
IN794MU2005 2005-08-05

Publications (2)

Publication Number Publication Date
WO2007017646A2 WO2007017646A2 (en) 2007-02-15
WO2007017646A3 true WO2007017646A3 (en) 2007-04-19

Family

ID=37649482

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/002919 WO2007017646A2 (en) 2005-08-05 2006-08-04 Anti-malarial composition comprising artesunate and lumefantrine

Country Status (3)

Country Link
GB (1) GB2443377A (en)
WO (1) WO2007017646A2 (en)
ZA (1) ZA200801208B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH696229A5 (en) * 2006-05-13 2007-02-28 Professeur Dr Achille Benakis Antimalarial composition in geometrical solid tablet form obtained by the compression of a medicine powder and excipients, useful to treat malaria, comprises three separate layers
FR2914860B1 (en) * 2007-04-12 2009-05-22 Ile D Inventeurs Apis Spheromo MULTILAYER SPHEROIDS WITH ANTIPALUDITIC ACTION IN WHICH ONE OF THE LAYERS CONTAINS ARTESUNATE
WO2010004573A1 (en) * 2008-07-07 2010-01-14 Ipca Laboratories Limited Synergistic antimalarial pharmaceutical composition
WO2011009956A1 (en) * 2009-07-24 2011-01-27 Dafra Pharma N.V. Injectable aqueous solution containing artesunate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002217A1 (en) * 1990-08-08 1992-02-20 Ciba-Geigy Ag Antimalarial compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002217A1 (en) * 1990-08-08 1992-02-20 Ciba-Geigy Ag Antimalarial compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FAIRLAMB ET AL: "INDEPENDENT REVIEW OF MEDICINES FOR MALARIA VENTURE", DFID HEALTH RESOURCE CENTRE, - 31 May 2005 (2005-05-31), London, GB, pages 1 - 28, XP002416195, Retrieved from the Internet <URL:http://www.mmv.org/IMG/pdf/MMV_Final_Report_7.7.05.pdf> *
WILLY KABUYA-MUTSHIPAYI: "Visit to Madagascar to Provide Technical Assistence for the Development of an Implementation Plan for the Transition to Artemisinin-Based Combination Therapies of Malaria Treatment", RATIONAL PHARMACEUTICAL MANAGMENT PLUS, - 31 May 2005 (2005-05-31), pages 1 - 11, XP002416194, Retrieved from the Internet <URL:http://pdf.dec.org/pdf_docs/PDACF086.pdf> *

Also Published As

Publication number Publication date
GB0804039D0 (en) 2008-04-09
GB2443377A (en) 2008-04-30
WO2007017646A2 (en) 2007-02-15
ZA200801208B (en) 2009-05-27

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