WO2007007183A3 - Compositions of antiviral compound - Google Patents

Compositions of antiviral compound Download PDF

Info

Publication number
WO2007007183A3
WO2007007183A3 PCT/IB2006/001952 IB2006001952W WO2007007183A3 WO 2007007183 A3 WO2007007183 A3 WO 2007007183A3 IB 2006001952 W IB2006001952 W IB 2006001952W WO 2007007183 A3 WO2007007183 A3 WO 2007007183A3
Authority
WO
WIPO (PCT)
Prior art keywords
ribavirin
compositions
antiviral compound
free flowing
agglomerating
Prior art date
Application number
PCT/IB2006/001952
Other languages
French (fr)
Other versions
WO2007007183A2 (en
Inventor
Amod Vishvanath Dhabu
Mohinder Paul Pakhetra
Ashish Gogia
Sivakumaran Meenakshisunderam
Original Assignee
Aurobindo Pharma Ltd
Amod Vishvanath Dhabu
Mohinder Paul Pakhetra
Ashish Gogia
Sivakumaran Meenakshisunderam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurobindo Pharma Ltd, Amod Vishvanath Dhabu, Mohinder Paul Pakhetra, Ashish Gogia, Sivakumaran Meenakshisunderam filed Critical Aurobindo Pharma Ltd
Priority to EP06765637A priority Critical patent/EP1904071A2/en
Publication of WO2007007183A2 publication Critical patent/WO2007007183A2/en
Publication of WO2007007183A3 publication Critical patent/WO2007007183A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom

Abstract

An oral pharmaceutical composition comprising free flowing ribavirin and one or more pharmaceutically acceptable excipients, wherein the free flowing ribavirin is prepared by agglomerating the non-free flowing ribavirin using a solvent or by controlling the crystallization during synthesis of ribavirin.
PCT/IB2006/001952 2005-07-08 2006-07-05 Compositions of antiviral compound WO2007007183A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06765637A EP1904071A2 (en) 2005-07-08 2006-07-05 Compositions of antiviral compound

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN906/CHE/2005 2005-07-08
IN906CH2005 2005-07-08

Publications (2)

Publication Number Publication Date
WO2007007183A2 WO2007007183A2 (en) 2007-01-18
WO2007007183A3 true WO2007007183A3 (en) 2007-08-23

Family

ID=37564409

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/001952 WO2007007183A2 (en) 2005-07-08 2006-07-05 Compositions of antiviral compound

Country Status (2)

Country Link
EP (1) EP1904071A2 (en)
WO (1) WO2007007183A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281715A1 (en) * 2001-07-30 2003-02-05 Clariant Life Science Molecules (Italia) SpA Process for the preparation of ribavirin
US20040258751A1 (en) * 2002-09-19 2004-12-23 Kerrish Donald J. Composition containing ribavirin and use thereof
EP1455801B1 (en) * 2001-12-21 2005-03-09 Biopartners GmbH Ribavirin granulate for producing coated tablets

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281715A1 (en) * 2001-07-30 2003-02-05 Clariant Life Science Molecules (Italia) SpA Process for the preparation of ribavirin
EP1455801B1 (en) * 2001-12-21 2005-03-09 Biopartners GmbH Ribavirin granulate for producing coated tablets
US20040258751A1 (en) * 2002-09-19 2004-12-23 Kerrish Donald J. Composition containing ribavirin and use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TONG H H Y ET AL: "An improved thermoanalytical approach to quantifying trace levels of polymorphic impurity in drug powders", INTERNATIONAL JOURNAL OF PHARMACEUTICS, AMSTERDAM, NL, vol. 295, no. 1-2, 13 May 2005 (2005-05-13), pages 191 - 199, XP004852854, ISSN: 0378-5173 *

Also Published As

Publication number Publication date
EP1904071A2 (en) 2008-04-02
WO2007007183A2 (en) 2007-01-18

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