WO2007002973A3 - Verwendung von stilbenderivaten zur herstellung von arzneimitteln für die behandlung solider tumore - Google Patents
Verwendung von stilbenderivaten zur herstellung von arzneimitteln für die behandlung solider tumore Download PDFInfo
- Publication number
- WO2007002973A3 WO2007002973A3 PCT/AT2006/000283 AT2006000283W WO2007002973A3 WO 2007002973 A3 WO2007002973 A3 WO 2007002973A3 AT 2006000283 W AT2006000283 W AT 2006000283W WO 2007002973 A3 WO2007002973 A3 WO 2007002973A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stilbene derivatives
- medicaments
- treatment
- production
- solid tumours
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Die Erfindung betrifft die Verwendung von Stilbenderivaten der allgemeinen Formel (I) zum Herstellen von Arzneimitteln für die Behandlung solider Tumore, wie Melanome oder Magenkarzinome. Neben der Antitumoraktivität als Einzelsubstanz konnten weiters zufriedenstellende Ergebnisse dann erzielt werden, wenn Stilbenderivate der allgemeinen Formel (I) in Kombination mit einer DNA-interkalierenden Substanz, insbesondere Dacarbazin verabreicht wurden.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0112505A AT502078A1 (de) | 2005-07-04 | 2005-07-04 | Verwendung von stilbenderivaten zur herstellung von arzneimitteln für die behandlung solider tumore |
ATA1125/2005 | 2005-07-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007002973A2 WO2007002973A2 (de) | 2007-01-11 |
WO2007002973A3 true WO2007002973A3 (de) | 2007-08-02 |
Family
ID=37496954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AT2006/000283 WO2007002973A2 (de) | 2005-07-04 | 2006-07-03 | Verwendung von stilbenderivaten zur herstellung von arzneimitteln für die behandlung solider tumore |
Country Status (2)
Country | Link |
---|---|
AT (1) | AT502078A1 (de) |
WO (1) | WO2007002973A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101912377A (zh) * | 2010-08-10 | 2010-12-15 | 王晓琴 | 紫檀芪在制备抗宫颈癌药物中的应用 |
CN103494793B (zh) * | 2013-09-26 | 2015-12-09 | 河南工业大学 | 3,4,5,3’,4’,5’-六甲氧基反式二苯乙烯在制备促血管生成药物中的应用 |
AU2022243973A1 (en) | 2021-03-25 | 2023-09-14 | Walter Jäger | Compounds for use in the treatment and prevention of covid- 19 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005016860A2 (de) * | 2003-08-14 | 2005-02-24 | Thomas Szekeres | Stilben-derivate und deren verwendung in arzneimitteln |
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2005
- 2005-07-04 AT AT0112505A patent/AT502078A1/de not_active Application Discontinuation
-
2006
- 2006-07-03 WO PCT/AT2006/000283 patent/WO2007002973A2/de active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005016860A2 (de) * | 2003-08-14 | 2005-02-24 | Thomas Szekeres | Stilben-derivate und deren verwendung in arzneimitteln |
Non-Patent Citations (5)
Title |
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ATTEN MARY JO ET AL: "Resveratrol regulates cellular PKC alpha and delta to inhibit growth and induce apoptosis in gastric cancer cells.", INVESTIGATIONAL NEW DRUGS MAR 2005, vol. 23, no. 2, March 2005 (2005-03-01), pages 111 - 119, XP002434067, ISSN: 0167-6997 * |
FUGGETTA MARIA PIA ET AL: "In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide.", MELANOMA RESEARCH JUN 2004, vol. 14, no. 3, June 2004 (2004-06-01), pages 189 - 196, XP009083923, ISSN: 0960-8931 * |
JEOUNG DOOIL ET AL: "Microarray analysis of piceatannol-induced changes in gene expression in human gastric cancer cells", BIOTECHNOLOGY LETTERS, vol. 24, no. 6, March 2002 (2002-03-01), pages 463 - 467, XP002434066, ISSN: 0141-5492 * |
LARROSA M ET AL: "The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human SK-Mel-28 melanoma cells", EUROPEAN JOURNAL OF NUTRITION 2004 GERMANY, vol. 43, no. 5, 2004, pages 275 - 284, XP002434065, ISSN: 1436-6207 * |
MURIAS M ET AL: "Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure-activity relationship", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB, vol. 69, no. 6, 15 March 2005 (2005-03-15), pages 903 - 912, XP004772315, ISSN: 0006-2952 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007002973A2 (de) | 2007-01-11 |
AT502078A1 (de) | 2007-01-15 |
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