WO2007002375A3 - Procédés et compositions pour l'analyse de microarn - Google Patents

Procédés et compositions pour l'analyse de microarn Download PDF

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Publication number
WO2007002375A3
WO2007002375A3 PCT/US2006/024448 US2006024448W WO2007002375A3 WO 2007002375 A3 WO2007002375 A3 WO 2007002375A3 US 2006024448 W US2006024448 W US 2006024448W WO 2007002375 A3 WO2007002375 A3 WO 2007002375A3
Authority
WO
WIPO (PCT)
Prior art keywords
microrna
methods
compositions
analysis
micrornas
Prior art date
Application number
PCT/US2006/024448
Other languages
English (en)
Other versions
WO2007002375A2 (fr
Inventor
Lori A Neely
Maria Hackett
Sonal Patel
Original Assignee
Us Genomics Inc
Lori A Neely
Maria Hackett
Sonal Patel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Genomics Inc, Lori A Neely, Maria Hackett, Sonal Patel filed Critical Us Genomics Inc
Publication of WO2007002375A2 publication Critical patent/WO2007002375A2/fr
Publication of WO2007002375A3 publication Critical patent/WO2007002375A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Abstract

La présente invention a trait à des procédés et des systèmes pour la détection et la mesure de microARN.
PCT/US2006/024448 2005-06-23 2006-06-23 Procédés et compositions pour l'analyse de microarn WO2007002375A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69333305P 2005-06-23 2005-06-23
US69333405P 2005-06-23 2005-06-23
US60/693,334 2005-06-23
US60/693,333 2005-06-23

Publications (2)

Publication Number Publication Date
WO2007002375A2 WO2007002375A2 (fr) 2007-01-04
WO2007002375A3 true WO2007002375A3 (fr) 2007-06-28

Family

ID=37595859

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/024448 WO2007002375A2 (fr) 2005-06-23 2006-06-23 Procédés et compositions pour l'analyse de microarn

Country Status (1)

Country Link
WO (1) WO2007002375A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8592384B2 (en) 2005-04-04 2013-11-26 The Board Of Regents Of The University Of Texas System Micro-RNA's that regulate muscle cells
WO2008040355A2 (fr) * 2006-10-06 2008-04-10 Exiqon A/S Nouveaux procédés de quantification de micro-arn et de petits arn interférants
CN102036689B (zh) 2008-03-17 2014-08-06 得克萨斯系统大学董事会 神经肌肉突触维持和再生中涉及的微小rna的鉴定
US20110028332A1 (en) * 2008-03-27 2011-02-03 Masahiko Kuroda Marker for diagnosis of breast cancer, test method, and test kit
CN101633925B (zh) * 2009-08-25 2011-08-31 南京医科大学 一种与精子生成障碍相关的精浆微小核糖核酸标志物及其应用
WO2011157617A1 (fr) * 2010-06-17 2011-12-22 Febit Holding Gmbh Ensemble complexe de banques de miarn
CN102296112B (zh) * 2011-08-09 2013-06-05 南京医科大学 人类非梗阻性无精子症相关的精浆微小核糖核酸标志物及其应用
EP3049539B1 (fr) * 2013-09-25 2018-09-05 Bio-Id Diagnostic Inc. Procédés de détection de fragments d'acide nucléique

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BABAK T. ET AL.: "Probing microRNAs with microarrays: Tissue specificity and functional inference", RNA, vol. 10, no. 11, November 2004 (2004-11-01), pages 1813 - 1819, XP002403367 *
JIANG J. ET AL.: "Cirrhosis-related microRNA expression profile in hepatocellular carcinoma and benign liver tissues", PROCEEDINGS OF THE 96TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, vol. 46, no. ABSTR. 4602, 16 April 2005 (2005-04-16) - 20 April 2005 (2005-04-20), ANAHEIM, CALIFORNIA, XP008082450 *
MASUKO M. ET AL.: "Optimization of excimer-forming two-probe nucleic acid hybridization method with pyrene as a fluorophore", NUCLEIC ACIDS RESEARCH, vol. 26, no. 23, 1 December 1998 (1998-12-01), pages 5409 - 5416, XP002932639 *
SCHMITTGEN T.D. ET AL.: "A high-throughput method to monitor the expression of microRNA precursors", NUCLEIC ACIDS RESEARCH, vol. 32, no. 4, 25 February 2004 (2004-02-25), pages E43, XP002389980 *
VALOCZI A. ET AL.: "Sensitive and specific detection of microRNAs by northem blot analysis using LNA-modified oligonucleotide probes", NUCLEIC ACIDS RES., vol. 32, no. 22, 14 December 2004 (2004-12-14), pages E175, XP002400290 *
ZENG Y. ET AL.: "Sequence requirements for micro RNA processing and function in human cells", RNA, vol. 9, no. 1, January 2003 (2003-01-01), pages 112 - 123, XP003014844 *

Also Published As

Publication number Publication date
WO2007002375A2 (fr) 2007-01-04

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