WO2006131401A3 - Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent - Google Patents

Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent Download PDF

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Publication number
WO2006131401A3
WO2006131401A3 PCT/EP2006/005831 EP2006005831W WO2006131401A3 WO 2006131401 A3 WO2006131401 A3 WO 2006131401A3 EP 2006005831 W EP2006005831 W EP 2006005831W WO 2006131401 A3 WO2006131401 A3 WO 2006131401A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
skin
film
controlled release
volatile solvent
Prior art date
Application number
PCT/EP2006/005831
Other languages
French (fr)
Other versions
WO2006131401A2 (en
Inventor
Philippe Andres
Claire Mallard
Original Assignee
Galderma Sa
Philippe Andres
Claire Mallard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa, Philippe Andres, Claire Mallard filed Critical Galderma Sa
Priority to BRPI0613230-8A priority Critical patent/BRPI0613230A2/en
Priority to CN2006800204905A priority patent/CN101247787B/en
Priority to MX2007015672A priority patent/MX2007015672A/en
Priority to EP06754427A priority patent/EP1901709A2/en
Priority to JP2008515155A priority patent/JP2008542423A/en
Priority to AU2006256860A priority patent/AU2006256860B2/en
Priority to CA002610755A priority patent/CA2610755A1/en
Publication of WO2006131401A2 publication Critical patent/WO2006131401A2/en
Publication of WO2006131401A3 publication Critical patent/WO2006131401A3/en
Priority to US12/000,187 priority patent/US20080153786A1/en
Priority to US12/714,739 priority patent/US20100216753A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention concerns a method for the controlled release of a drug through skin, which method comprises topically administering a composition that comprises at least one solubilized drug, a film-forming silicone, and at least one volatile solvent.
PCT/EP2006/005831 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent WO2006131401A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
BRPI0613230-8A BRPI0613230A2 (en) 2005-06-10 2006-05-22 method for controlled release of a drug, method of administration, method of treating skin disorders, controlled release composition and use of a composition
CN2006800204905A CN101247787B (en) 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent
MX2007015672A MX2007015672A (en) 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent.
EP06754427A EP1901709A2 (en) 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent
JP2008515155A JP2008542423A (en) 2005-06-10 2006-05-22 Method for controlled release of drugs through the skin
AU2006256860A AU2006256860B2 (en) 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent
CA002610755A CA2610755A1 (en) 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent
US12/000,187 US20080153786A1 (en) 2006-05-22 2007-12-10 Controlled release of drugs into/through the skin
US12/714,739 US20100216753A1 (en) 2005-06-10 2010-03-01 Controlled release of drugs into/through the skin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68928205P 2005-06-10 2005-06-10
US60/689,282 2005-06-10

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/000,187 Continuation US20080153786A1 (en) 2005-06-10 2007-12-10 Controlled release of drugs into/through the skin

Publications (2)

Publication Number Publication Date
WO2006131401A2 WO2006131401A2 (en) 2006-12-14
WO2006131401A3 true WO2006131401A3 (en) 2007-03-15

Family

ID=37137556

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/005831 WO2006131401A2 (en) 2005-06-10 2006-05-22 Controlled release of a drug through skin on the basis of a topical composition comprising a drug, a film-forming silicone and at least one volatile solvent

Country Status (11)

Country Link
EP (1) EP1901709A2 (en)
JP (1) JP2008542423A (en)
KR (1) KR20080016612A (en)
CN (1) CN101247787B (en)
AR (1) AR054381A1 (en)
AU (1) AU2006256860B2 (en)
BR (1) BRPI0613230A2 (en)
CA (1) CA2610755A1 (en)
MX (1) MX2007015672A (en)
RU (1) RU2008100037A (en)
WO (1) WO2006131401A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2909284B1 (en) * 2006-11-30 2012-09-21 Galderma Sa NOVEL VASELIN-FREE OINTMENTAL COMPOSITIONS COMPRISING VITAMIN D DERIVATIVE AND POSSIBLY STEROID ANTI-INFLAMMATORY
CA2680279A1 (en) * 2007-03-08 2008-09-12 Biozone Laboratories Inc. Dressing formulations to prevent and reduce scarring
EP2167036B1 (en) * 2007-07-11 2013-09-18 Dow Corning Corporation Compositions for delivering a drug
CN102480969A (en) * 2009-07-09 2012-05-30 科锐医疗有限公司 Method of wound healing and scar modulation
US9254296B2 (en) 2009-12-22 2016-02-09 Leo Pharma A/S Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture
RU2500387C1 (en) * 2009-12-22 2013-12-10 Лео Фарма А/С Pharmaceutical composition containing vitamin d analogue and mixed co-solvent and surfactant
US20160095876A1 (en) 2014-10-01 2016-04-07 Rochal Industries, Llp Composition and kits for inhibition of pathogenic microbial infection and methods of using the same
TW201636025A (en) * 2015-04-15 2016-10-16 Maruho Kk Pharmaceutical composition for skin
KR20190026397A (en) 2017-09-05 2019-03-13 안준배 noise filtering device and method

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0410099A1 (en) * 1989-06-27 1991-01-30 American Cyanamid Company Stable, cosmetically acceptable topical gel formulation and method of treatment for acne
WO2000073374A1 (en) * 1999-05-28 2000-12-07 Neutrogena Corporation Silicone gel containing salicylic acid
WO2000072817A1 (en) * 1999-05-28 2000-12-07 Neutrogena Corporation Water-in-oil emulsion comprising a silicone gel containing vitamin c
EP1132430A1 (en) * 2000-03-10 2001-09-12 Wacker-Chemie GmbH Organopolysiloxane gels for use in cosmetics
WO2001078661A2 (en) * 2000-04-18 2001-10-25 Wella Aktiengesellschaft Aerosol foam for treating hair
EP1163951A2 (en) * 2000-06-14 2001-12-19 Dow Corning Corporation Water-in-oil-polar solvent emulsions
WO2004103323A1 (en) * 2003-05-16 2004-12-02 The Procter & Gamble Company Personal care products comprising active agents in a gel network
WO2005053666A1 (en) * 2003-11-21 2005-06-16 Galderma Research & Development, S.N.C. Sprayable composition for the administration of vitamin d derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03275619A (en) * 1990-03-23 1991-12-06 Nitsusui Seiyaku Kk External agent composition
JP3251717B2 (en) * 1992-06-29 2002-01-28 花王株式会社 External preparation for skin
JP3573803B2 (en) * 1994-02-16 2004-10-06 ポーラ化成工業株式会社 External preparation for skin
AU1876797A (en) * 1996-03-16 1997-10-10 Hoechst Aktiengesellschaft Topical formulations for the treatment of nail psoriasis
GB9902812D0 (en) * 1998-06-18 1999-03-31 Dow Corning Sa Composition for delivering pharmaceutically active agents
CA2423930C (en) * 2000-10-27 2009-11-24 Leo Pharma A/S Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid
JP2004189639A (en) * 2002-12-09 2004-07-08 Pola Chem Ind Inc Emulsified composition
FR2871697B1 (en) * 2004-06-17 2007-06-29 Galderma Sa SPRAY COMPOSITION COMPRISING AN ASSOCIATION OF PHARMACEUTICAL ASSETS, AN ALCOHOLIC PHASE, AT LEAST ONE VOLATILE SILICONE AND A NON-VOLATILE OIL PHASE

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0410099A1 (en) * 1989-06-27 1991-01-30 American Cyanamid Company Stable, cosmetically acceptable topical gel formulation and method of treatment for acne
WO2000073374A1 (en) * 1999-05-28 2000-12-07 Neutrogena Corporation Silicone gel containing salicylic acid
WO2000072817A1 (en) * 1999-05-28 2000-12-07 Neutrogena Corporation Water-in-oil emulsion comprising a silicone gel containing vitamin c
EP1132430A1 (en) * 2000-03-10 2001-09-12 Wacker-Chemie GmbH Organopolysiloxane gels for use in cosmetics
WO2001078661A2 (en) * 2000-04-18 2001-10-25 Wella Aktiengesellschaft Aerosol foam for treating hair
EP1163951A2 (en) * 2000-06-14 2001-12-19 Dow Corning Corporation Water-in-oil-polar solvent emulsions
WO2004103323A1 (en) * 2003-05-16 2004-12-02 The Procter & Gamble Company Personal care products comprising active agents in a gel network
WO2005053666A1 (en) * 2003-11-21 2005-06-16 Galderma Research & Development, S.N.C. Sprayable composition for the administration of vitamin d derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1901709A2 *

Also Published As

Publication number Publication date
KR20080016612A (en) 2008-02-21
CA2610755A1 (en) 2006-12-14
MX2007015672A (en) 2008-02-20
AU2006256860B2 (en) 2012-04-19
BRPI0613230A2 (en) 2011-01-04
CN101247787B (en) 2011-10-05
EP1901709A2 (en) 2008-03-26
JP2008542423A (en) 2008-11-27
RU2008100037A (en) 2009-07-20
AU2006256860A1 (en) 2006-12-14
AR054381A1 (en) 2007-06-20
WO2006131401A2 (en) 2006-12-14
CN101247787A (en) 2008-08-20

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