WO2006130689A3 - Detecting prostate cancer - Google Patents

Detecting prostate cancer Download PDF

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Publication number
WO2006130689A3
WO2006130689A3 PCT/US2006/021118 US2006021118W WO2006130689A3 WO 2006130689 A3 WO2006130689 A3 WO 2006130689A3 US 2006021118 W US2006021118 W US 2006021118W WO 2006130689 A3 WO2006130689 A3 WO 2006130689A3
Authority
WO
WIPO (PCT)
Prior art keywords
prostate cancer
detecting prostate
materials
methods
dipeptidylpeptidase
Prior art date
Application number
PCT/US2006/021118
Other languages
French (fr)
Other versions
WO2006130689A2 (en
Inventor
Michael J Wilson
Neil F Wasserman
Akhouri Sinha
Original Assignee
Univ Minnesota
Michael J Wilson
Neil F Wasserman
Akhouri Sinha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota, Michael J Wilson, Neil F Wasserman, Akhouri Sinha filed Critical Univ Minnesota
Publication of WO2006130689A2 publication Critical patent/WO2006130689A2/en
Publication of WO2006130689A3 publication Critical patent/WO2006130689A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

This document provides methods and materials related to detecting prostate cancer. For example, methods and materials for assessing the likelihood of prostate cancer in a mammal by determining the level of a dipeptidylpeptidase IV polypeptide are provided. Methods and materials for assessing prostate cancer progression and prostate cancer regression in a mammal by determining the level of a dipeptidylpeptidase IV polypeptide also are provided.
PCT/US2006/021118 2005-06-02 2006-06-01 Detecting prostate cancer WO2006130689A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68667305P 2005-06-02 2005-06-02
US60/686,673 2005-06-02

Publications (2)

Publication Number Publication Date
WO2006130689A2 WO2006130689A2 (en) 2006-12-07
WO2006130689A3 true WO2006130689A3 (en) 2007-12-06

Family

ID=37482264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/021118 WO2006130689A2 (en) 2005-06-02 2006-06-01 Detecting prostate cancer

Country Status (1)

Country Link
WO (1) WO2006130689A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008151238A1 (en) * 2007-06-04 2008-12-11 The Johns Hopkins University Biomarkers for prostate cancer
SE535084C2 (en) * 2010-04-16 2012-04-10 Prostasom Handelsbolag Procedure for cancer diagnosis

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ADBEL-KHALEK ET AL.: "Is transition zone biopsy vuluable in benign prostatic hyperplasia patients with serum prostate-specific antigen >10 ng/ml and prior negative peripheral zone biopsy?", SCAND. J. UROL. NEPHROL., vol. 39, no. 1, 2005, pages 49 - 55, XP008091907 *
BOGENRIEDER ET AL.: "Expression and localization of aminopeptidase A, aminopeptidase N, and dipeptidyl peptidase IV in benign and malignant human prostate tissue", PROSTATE, vol. 33, no. 4, 1 December 1997 (1997-12-01), pages 225 - 232, XP009058196 *
DURKAN ET AL.: "Improving prostate cancer detection with an extended-core transrectal ultrasonography-guided prostate biopsy protocol", BJU INT., vol. 89, no. 1, January 2002 (2002-01-01), pages 33 - 39, XP008091292 *
JALAL ET AL.: "Polarized distribution of neutral endopeptidase 24.11 at the cell surface of cultured human intestinal epithelial Caco-2 cells", BIOCHEM. J., vol. 288, no. 3, 15 December 1992 (1992-12-15), pages 945 - 951, XP008091212 *
WILSON ET AL.: "Dipeptidylpeptidase IV activities are elevated in prostate cancers and adjacent benign hyperplastic glands", J. ANDROL., vol. 21, no. 2, March 2000 (2000-03-01) - April 2000 (2000-04-01), pages 220 - 226, XP008091383 *
WILSON ET AL.: "Dipeptidylpeptidase IV activities in prostatic secretions", ADV. EXP. MED. BIOL., vol. 524, 2003, pages 257 - 260, XP008091178 *
WILSON ET AL.: "Elevation of dipeptidylpeptidase iv activities in the prostate peripheral zone and prostatic secretions of men with prostate cancer: possible prostate cancer disease marker", J. UROL., vol. 174, no. 3, September 2005 (2005-09-01), pages 1124 - 1128, XP005382410 *

Also Published As

Publication number Publication date
WO2006130689A2 (en) 2006-12-07

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