WO2006120890A1

WO2006120890A1 - Tube and liquid feeder

Info

Publication number: WO2006120890A1
Application number: PCT/JP2006/308617
Authority: WO
Inventors: Souichi Ooue; Takato Murashita; Masaaki Kasai
Original assignee: Terumo Kabushiki Kaisha
Priority date: 2005-05-06
Filing date: 2006-04-25
Publication date: 2006-11-16
Also published as: JPWO2006120890A1; JP4970261B2

Abstract

A tube for passing a liquid therein and a liquid feeder. The tube comprises a tube body in which a flow passage allowing the liquid to pass therein is formed and expanded/contracted due to a change in temperature and restriction members fitted to at least parts of the tube body in the longitudinal direction and restricting the outer diameter of the tube body. In the tube of this structure, the cross sectional areas of the flow passage at portions where the restriction members are fitted are changed according to the expansion/contraction of the tube body due to a change in temperature.

Description

Specification

Tube and liquid supply

Technical field

[0001] The present invention relates to a tube through which a liquid passes and a liquid supply device including the tube.

Background art

[0002] For example, as a chemical solution injection device (medical solution supply device) for administering a chemical solution to a patient, one used in a medical institution such as a hospital, and one who is self-administered at home or at work. Some are used when administered. For example, in order to manage pain such as postoperative pain and cancer pain, a microinjection of an analgesic agent such as morphine is continuously performed using a drug solution injector.

[0003] Such a chemical solution injector mainly includes a chemical solution supply source such as a balloon or a syringe pump having a function of storing the chemical solution and discharging the chemical solution, and an extended chemical solution supply source. Line and a flow rate control device installed in the middle of the chemical solution supply line. The flow control device has an orifice with a small cross-sectional area of the flow path (having an ultra-fine flow path), and controls the flow rate in a very small amount by a large pipe resistance when the chemical solution passes through the orifice. (For example, see JP-A-10-295811).

[0004] However, in the chemical solution supply device having such a configuration, it is necessary to accurately secure the dose of the chemical solution to the patient. However, due to the change in use temperature (room temperature) at which the chemical solution supply device is used. Therefore, the flow rate of the chemical solution may change, that is, the dosage may change. In other words, in the chemical solution supply device having such a configuration, the viscosity of the chemical solution and the diameter of the orifice channel may change due to a change in room temperature, and the flow rate of the chemical solution passing through the channel may change. Atsuta. For example, when the room temperature rises, the viscosity of the chemical solution decreases as the temperature rises, and the orifice expands to increase the diameter of the flow path. Thereby, the flow volume of a chemical | medical solution increases.

[0005] As described above, there has been a problem that a change in the flow rate of the chemical solution, that is, an error occurs, and it may be difficult to ensure an accurate dose of the chemical solution.

Disclosure of the invention [0006] An object of the present invention is to provide a tube and a liquid supply device that can prevent the flow rate of the liquid passing through the flow path from being changed due to a temperature change.

[0007] (1) In order to achieve the above object, the tube of the present invention comprises:

A tube through which liquid passes;

A tube body that forms a flow path through which liquid can pass and expands and contracts due to changes in temperature.

Provided in at least a part of the longitudinal direction of the tube body, and a regulating member for regulating the outer diameter of the tube body,

The tube is characterized in that the cross-sectional area of the flow path changes as the tube body expands and contracts due to the temperature change at the portion where the regulating member is provided.

[0008] Thereby, it is possible to reliably prevent the flow rate of the liquid passing through the flow path from changing due to a temperature change.

[0009] (2) In the tube of the present invention, when the liquid passes through the flow path, the degree of expansion Z contraction of the tube body due to the temperature change is such that the flow rate of the liquid becomes constant. It is preferred to be set.

[0010] Thereby, it is possible to more reliably prevent the flow rate of the liquid passing through the flow path from changing due to a temperature change.

[0011] (3) Further, in the tube of the present invention, it is preferable that the regulating member has a smaller coefficient of thermal expansion than the tube body.

[0012] Thereby, it is possible to more reliably prevent the flow rate of the liquid passing through the flow path from changing due to a temperature change.

[0013] (4) In the tube of the present invention, it is preferable that the restricting member is provided over substantially the entire length in the longitudinal direction of the tube main body.

[0014] Thereby, it is possible to more reliably prevent the flow rate of the liquid passing through the flow path from changing due to a temperature change.

[0015] (5) In the tube of the present invention, it is preferable that a plurality of the regulating members are provided at intervals along the longitudinal direction of the tube body. [0016] Thereby, the rate of change in the cross-sectional area of the flow path can be reduced.

[0017] (6) In the tube of the present invention, the tube body includes a laminated portion having an inner layer and an outer layer provided on an outer peripheral side of the inner layer and made of a material different from the inner layer, The regulating member is preferably provided on the outer peripheral side of the outer layer.

[0018] Thereby, the rate of change in the cross-sectional area of the flow path can be set more appropriately, thus

Further, it is possible to more reliably prevent the flow rate of the liquid passing through the flow path from changing due to a temperature change.

[0019] (7) In the tube of the present invention, it is preferable that the outer layer has a higher coefficient of thermal expansion than the inner layer.

[0020] Thereby, the rate of change in the cross-sectional area of the flow path can be set more appropriately, and thus the flow rate of the liquid passing through the flow path can be more reliably prevented from changing due to a temperature change. it can.

[0021] (8) Further, in the tube of the present invention, it is preferable that the regulating member has a substantially cross-sectional shape in a cross section! /.

[0022] Thereby, it is possible to more reliably prevent the flow rate of the liquid passing through the flow path from changing due to a temperature change.

[0023] (9) In the tube of the present invention, it is preferable that the regulating member is mainly made of a metal material.

[0024] Thereby, the coefficient of thermal expansion is surely smaller than that of the tube body, and the regulating member can be formed (configured).

[0025] (10) In the tube of the present invention, it is preferable that the liquid is a chemical solution to be administered into a living body.

[0026] Thereby, it is possible to reliably prevent the flow rate of the chemical solution passing through the flow path from changing due to a temperature change.

[0027] (11) In order to achieve the above object, the liquid supply device of the present invention comprises:

A liquid supply tool comprising the tube according to any one of (1) and (10) above, and having a flow rate adjusting unit for adjusting the flow rate of the liquid.

[0028] This prevents the flow rate of the liquid passing through the flow path from changing due to a temperature change. Togashi.

Brief Description of Drawings

FIG. 1 is a cross-sectional side view showing a liquid supply tool of the present invention.

FIG. 2 is an exploded view of the liquid supply tool shown in FIG. 1.

FIG. 3 is a plan view of the liquid supply tool shown in FIG. 1.

FIG. 4 is a plan view showing a state in which the upper cover of the liquid supply tool shown in FIG. 1 is removed.

FIG. 5 is a plan view showing a state where an upper cover of the liquid supply tool shown in FIG. 1 is removed.

FIG. 6 is a plan view showing a state in which the upper cover of the liquid supply tool shown in FIG. 1 has been removed.

FIG. 7 is a perspective view showing a first embodiment of the tube of the present invention.

FIG. 8 is a perspective view when the tube shown in FIG. 7 is deformed by a temperature change.

FIG. 9 is a perspective view when the tube shown in FIG. 7 is deformed by a temperature change.

FIG. 10 is a perspective view showing a second embodiment of the tube of the present invention.

FIG. 11 is a perspective view showing a third embodiment of the tube of the present invention.

FIG. 12 is a perspective view showing a fourth embodiment of the tube of the present invention.

FIG. 13 is a graph showing the relationship between the temperature and the flow rate of water passing through the tube. BEST MODE FOR CARRYING OUT THE INVENTION

Hereinafter, the tube and the liquid supply tool of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings. In the present embodiment, the liquid that passes through the inside of the tube of the present invention is used as a liquid that is administered into a living body, and the liquid supply device of the present invention is used as a liquid medicine supply device that supplies the liquid medicine. It becomes an embodiment.

FIG. 1 is a sectional side view showing a liquid supply tool of the present invention, FIG. 2 is an exploded view of the liquid supply tool shown in FIG. 1, and FIG. 3 is a liquid supply tool shown in FIG. Fig. 4, Fig. 5, Fig. 5 and Fig. 6 show the state where the upper cover of the liquid supply tool shown in Fig. 1 is removed. FIG.

[0032] The left side in FIGS. 1 to 6 is referred to as "upstream side", the right side is referred to as "downstream side", the upper side in FIGS. 1 and 2 is referred to as "upper", and the lower side is referred to as "upper side". This will be described as “below”.

[0033] As shown in FIG. 1 to FIG. 6, the chemical solution supply device (liquid supply device) 1 of the present invention is mainly mounted on the first lower case 3, the second lower case 4, and the upper parts thereof. And a casing 2 composed of the upper case 5.

[0034] The first lower case 3 includes a chamber 1 (chemical solution storage unit) 31 for storing a chemical solution, and the chamber

A force S is formed with the inflow ports 32a and 32b and the outflow port 33 of the chemical solution communicating with 31.

The chamber 31 is defined by a cylindrical recess formed in the center of the first lower case 3 and a diaphragm 7 attached to the upper part. The volume of the chamber 31 is not particularly limited, but usually about 0.3 to 5. OmL is preferable, and about 2.0 to 3. OmL is more preferable.

The second lower case 4 is joined to the upstream side of the first lower case 3, and stores a flow rate switching means (flow rate adjusting unit) 9 described later between the upper case 5 and the second lower case 4. On the inner surface of the bottom of the second lower case 4, a recess 41 is formed that serves as a bearing for the operation dial 91 of the flow rate switching means 9. Similarly, an opening 56 serving as a bearing for the operation dial 91 is formed at a corresponding position of the upper case 5.

[0037] On the downstream side of the upper case 5, there is formed a raised portion 51 that protrudes upwardly, and a one-shot injection (a predetermined amount of a medicinal solution Q is temporarily injected into the patient). The operation means 6 having a discharge amount adjusting mechanism for adjusting the discharge amount of the chemical liquid Q from the outlet 33 at the time of carrying out is housed.

[0038] That is, a circular opening 52 into which the button blade and the udging 61 are movably inserted in the vertical direction is formed at the top of the raised portion 51. At the lower end of the opening 52, a first stepped portion 53 that increases the cross-sectional area of the opening 52 and a second stepped portion 54 that further increases the cross-sectional area are formed.

The button housing 61 is a ring-shaped member, and a female screw 67 is formed on the inner peripheral surface thereof.

[0040] Further, the button (presser) 62 presses the diaphragm 7 and presses it inside the chamber 31. It is made up of a substantially cylindrical member having a contact surface 63 that contacts the membrane 72 of the diaphragm 7 at the lower end thereof.

[0041] On the upper outer peripheral surface of the button 62, a male screw 66 that is screwed with the female screw 67 is formed. When the male screw 66 is screwed with the female screw 67, the button 62 is inserted inside the button housing 61.

[0042] Then, by adjusting the rotation direction and the rotation amount of the button 62 with respect to the button housing 61, the vertical position of the button 62 with respect to the button housing 61, that is, the distance between the button 62 and the diaphragm 7 (separation distance). Is adjusted and set. In the state shown in FIG. 1, the contact surface 63 of the button 62 and the membrane 72 of the diaphragm 7 are in contact. The contact surface 63 of the button 62 and the membrane 72 of the diaphragm 7 are in contact with each other as described above. For example, the contact surface 63 of the button 62 is separated from the membrane 72 by a predetermined distance. May be.

[0043] When the button 62 is pressed to project the diaphragm 7 to the inside of the chamber 31, the volume of the chamber 31 is temporarily reduced, and the chemical Q in the chamber 31 is discharged from the outlet 33. . This discharge amount corresponds to the vertical position of the button 62 with respect to the button housing 61.

[0044] In the present embodiment, since the discharge amount adjusting mechanism by screwing the female screw 67 and the male screw 66 is provided, the position of the button 62 in the vertical direction with respect to the button housing 61, that is, the button 62 is changed. The amount of projection (insertion state) of the membrane 72 of the diaphragm 7 into the chamber 31 during the pressing operation (one-shot injection operation) can be adjusted steplessly. Q discharge amount can be adjusted.

[0045] In addition, since the discharge amount adjustment mechanism is a mechanism that adjusts the distance (separation distance) between the button 62 and the diaphragm 7, it is always possible to discharge the chemical Q from the chamber 31 ( The adjustment can be made (for example, even during microinjection).

A groove 64 for rotating the button 62 with respect to the button housing 61 is formed on the upper surface of the button 62. For example, a coin or a screwdriver is inserted into the groove 64, the button 62 is rotated with respect to the button nosing 61, and the vertical position thereof is adjusted and set.

[0047] In addition, the chemical supply tool 1 is provided with a rotation stopping mechanism for preventing the button housing 61 from rotating with respect to the upper case 5 when the button 62 is rotated as described above. RU . That is, as shown in FIG. 3, a pair of grooves 611 extending in a direction perpendicular to the paper surface in FIG. 1 is formed on the outer peripheral surface of the button housing 61, while the groove 611 of the upper case 5 is formed in the groove 611 of the upper case 5. At the corresponding position, a ridge 55 to be inserted into the groove 611 is formed. When the button housing 61 is moved in the vertical direction (vertical direction), the ridge 55 slides along the groove 611 and moves. Although it is possible, when the rotational stress is applied to the upper case 5 of the button housing 61, the protrusion 55 and the groove 611 are engaged with each other, so that the rotation is prevented. As a result, the button nosing 61 can move only in the vertical direction in FIG.

[0048] The button housing 61 and the button 62 held by the button housing 61 are urged upward by a coiled panel (biasing member) 65 in a compressed state.

The upper end portion of the panel 65 is inserted into a panel seat 612 made of a ring-shaped recess formed in the button housing 61, and the lower end of the panel 65 is in contact with the upper surface of the clamping member 8. When the panel 65 is most contracted, all or most of the panel 65 is stored in the panel seat 612.

[0050] A flange 613 is formed on the outer peripheral portion of the lower end of the button housing 61, and the button housing 61 urged upward by the panel 65 is engaged with the first stepped portion 53 of the flange 613. This limits the upward movement limit.

The diaphragm 7 is composed of a ring-shaped rim portion 71 and a film (thin wall portion) 72 formed on the inside thereof. The diaphragm 7 seals the upper surface opening of the cylindrical concave portion formed in the first lower case 3 in a liquid-tight manner, that is, defines the upper surface (part) of the chamber 31.

[0052] This diaphragm 7 is made of, for example, various rubber materials such as natural rubber, isoprene rubber, butadiene rubber, styrene butadiene rubber, butyl rubber, silicone rubber, fluoro rubber, and various heat materials such as polyurethane, polyester, and polyamide. It is preferably made of an elastic material (elastic material) such as a plastic elastomer. Among these, silicone rubber is especially preferred because of its high stability against chemical Q!

The diaphragm 7 is sandwiched between the first lower case 3 and a ring-shaped sandwiching member 8 located at the upper part thereof, and maintains the liquid tightness of the upper part of the chamber 31. That is, the rim portion 71 of the diaphragm 7 is inserted in a state of being compressed in the vertical direction into the concave portions 81 formed by ring-shaped groove caps formed in the first lower case 3 and the clamping member 8 respectively. And rim part A film 72 in the vicinity of the inner side from 71 is sandwiched between the lip 34 formed on the upper outer peripheral edge of the chamber 31 of the first lower case 3 and the lower surface of the clamping member 8.

[0054] In this case, the outer peripheral portion of the clamping member 8 engages with the second step portion 54 of the upper case 5 and receives a pressing force downward from the second step portion 5, thereby the first lower portion The clamping force between case 3 and clamping member 8 is obtained. Therefore, the diaphragm 7 is sandwiched between the first lower case 3 and the upper case 5 via the sandwiching member 8.

[0055] A circular opening 82 through which the button 62 can pass is formed at the center of the clamping member 8.

The first lower case 3 is formed with a pair of inflow ports 32a and 32b and an outflow port 33 communicating with the chamber 31.

[0056] The downstream ends of the first tube 10a and the second tube 10b are liquid-tightly inserted into the inflow ports 32a and 32b, respectively! Speak.

[0057] At the downstream ends of the first tube 10a and the second tube 10b, channels l la and l ib having a small cross-sectional area are formed, respectively, and the chemical solution Q passes through the channels l la and l ib. At the same time, a large pipe resistance (viscous resistance) is received from the inner surface of each flow path, and the flow rate is controlled to a very small amount.

[0058] In this case, the flow path 1 la and the flow path 1 lb have different cross-sectional areas of the flow paths! /. That is, since the cross-sectional area of the flow path 11a is smaller than the cross-sectional area of the flow path l ib, the flow rate V of the chemical liquid Q passing through the flow path 11a is smaller than the flow rate V of the chemical liquid Q passing through the flow path l ib. .

1 2

[0059] Further, the upstream sides of the first tube 10a and the second tube 10b are each flexible so that they can be deformed when the tubes are closed. Those having a restoring property of 1 are preferable. Examples of constituent materials that satisfy such conditions include various synthetic resins such as soft polychlorinated butyl, polyethylene, polypropylene, ethylene acetate butyl copolymer, polyamide, polyester, and polyurethane, natural rubber, and polystyrene-butadiene rubber. And various rubbers such as butyl rubber, silicone rubber and isoprene, and various thermoplastic elastomers.

[0060] The upstream ends of the first tube 10a and the second tube 10b are connected to the tube 14 via the Y-shaped connector 13. The tube 14 projects out of the casing 2, and the upstream end of the tube 14 is connected to a chemical supply source (not shown) such as a syringe pump or a balloon. It is connected.

[0061] On the downstream side of the outlet 33, there is an enlarged portion 35 whose inner diameter is enlarged, and the connector 15 is fitted in the enlarged portion 35 in a liquid-tight manner.

A one-way valve (check valve) 16 that restricts the flow of the chemical solution Q in one direction from the upstream side to the downstream side is installed on the upstream side inside the connector 15. As a result, the chemical liquid Q flows backward and is prevented from flowing into the chamber 31 through the outlet 33.

A tube 17 is connected to the downstream side of the connector 15. For example, a puncture needle (not shown) is attached to the downstream end of the tube 17, and the drug solution Q can be administered by puncturing the puncture needle into the blood vessel or epidural surface of the patient.

[0064] The tubes 14 and 17 each have flexibility (softness), and those having a certain degree of resilience are particularly preferable. Examples of the constituent material of the tubes 14 and 17 satisfying such conditions include various synthetic resins such as soft polysalt cellulose, polyethylene, polypropylene, ethylene-vinyl acetate copolymer, polyamide, polyester, and polyurethane, Various rubbers such as natural rubber, styrene butadiene rubber, butyl rubber, and silicone rubber, and various thermoplastic elastomers can be used.

[0065] In addition, the inner surfaces of the tubes 14 and 17 can be subjected to a surface treatment that does not adversely affect the chemical Q (particularly, formation of a coating layer). The purpose of the surface treatment is arbitrary.For example, a hydrophilic layer is formed to prevent organic components in the tube constituent material from eluting into the chemical solution Q or to prevent air blocking. Can be mentioned.

[0066] The flow rate switching means (flow rate adjustment unit) 9 switches (adjusts) the flow rate of the liquid, and an operation dial (operation member) having a first tube 10a and a second tube 10b and a pressure closing unit 92. 91 and the pressure closing part 92, the tube pressure closing mechanism composed of receiving members 94a and 94b for pressing and closing the first tube 10a and the second tube 10b, respectively, and the positioning of the operation dial 91 in the rotational direction. It consists of positioning means 95 to perform.

[0067] The operation dial 91 is rotatably supported with respect to the casing 2 by the concave portion 41 functioning as a bearing and the opening 56, and below the operation dial 91 is displaced with respect to the receiving members 94a and 94b and is displaced by the first tube. A cam-shaped crushing portion 92 that can selectively crush 10a and the second tube 10b is formed. It is made. In addition, a grip portion 93 that grips the operation dial 91 to rotate is formed on the operation dial 91.

[0068] The receiving members 94a and 94b are installed in contact with the inner surface of the upstream side wall of the casing 2, respectively. Each of the receiving members 94a and 94b is formed with a protrusion 941 that protrudes toward the operation dial 91. The projecting portion 941 and the pressure closing portion 92 of the operation dial 91 close the first tube 10a and the second tube 10b, and close the flow paths (internal flow paths) lla and lib.

[0069] In the present embodiment, the receiving members 94a and 94b are integrated with the second lower case 4, but may be separate members.

[0070] The positioning means 95 includes three concave portions 96 &, 96b, 96c formed on the outer peripheral surface of the operation dial 91 on the side opposite to the pressure closing portion 92 at substantially equal intervals, and a tip force concave portion 96 &, 96b, 96c V, Pin 97 selectively inserted in the gap, coil-shaped panel (biasing member) 98 that urges the pin 97 toward the operation dial 91 side, and stopper 99 Has been.

[0071] The pin 97 and the panel 98 are inserted into the hole 43 of the support portion 42 erected from the bottom of the second lower case 4, and the tip of the pin 97 protrudes from the downstream end of the hole 43. ing. Further, a stopper 99 is fitted into the upstream end portion of the hole 43 and sealed. A panel 98 is inserted between the pin 97 and the stopper 99 in a compressed state to urge the pin 97 downstream.

[0072] The tip end of the pin 97 is urged by the screw 98 and is inserted into the ヽ 96a, 96b, 96c displacement force, and in this state, the position of the operation dial 91 in the rotational direction stops, Positioning is performed.

That is, the positioning means 95 sets the operation dial 91 in the rotational direction in three stages (first state, second state, and third state) (FIGS. 4 to 6). According to this, the pattern in which the first tube 10a and the second tube 10b are closed and sealed is selected, and the flow rate of the chemical solution Q is set.

That is, as shown in FIG. 4, in the state where the tip end portion of the pin 97 is inserted into the central recess 96b (third state Z reference position), the first tube 10a and the second tube 10b Both are not closed, so that the chemical Q passes through the flow paths 11a and l ib of the first tube 10a and the second tube 10b, respectively, and passes through the inlets 32a and 32b. Flows into 1. Therefore, the flow rate V of the chemical solution Q at this time is the flow rate V and the flow rate V.

The maximum flow rate is almost equal to the sum of 3 1 2.

[0075] Further, as shown in FIG. 5, when the tip end of the pin 97 is inserted into the recess 96a (first state), the first tube of the first tube 10a and the second tube 10b is the first tube. Only 10a is closed, so that the chemical Q passes through the flow path ib of the second tube 10b and flows into the chamber 31 through the inlet 32b. At this time, the flow rate of the chemical solution Q becomes the flow rate V.

2

[0076] Also, as shown in FIG. 6, when the tip of the pin 97 is inserted into the recess 96c (second state), the second tube out of the first tube 10a and the second tube 10b. Only the liquid 10b is closed, so that the chemical Q passes through the flow path 11a of the first tube 10a and flows into the chamber 31 through the inlet 32a. The flow rate of the chemical solution Q at this time is the flow rate V (<V).

1 2

[0077] As described above, the flow rate switching means 9 selects the chemical solution Q by selecting the distribution pattern of the chemical solution Q to each of the two flow paths l la and l ib (the first tube 10a and the second tube 10b). The flow rate of V is set to three levels: V, V, and V (which satisfy the relationship V <V <V)

1 2 3 1 2 3

You can. By setting the positioning means 95, such a flow rate setting operation can be easily and accurately performed.

[0078] In the present invention, when three or more tubes are used (not shown),

By combining them (patterns), the flow rate can be set at a level higher than the number of tubes (flow paths), and finer flow rate adjustment (flow rate switching) becomes possible.

Further, a scale 18 indicating the position of the operation dial 91 in the rotational direction, that is, the magnitude of the flow rate of the chemical liquid Q is formed. As a result, the flow rate can be adjusted more easily and without erroneous operation.

[0080] Further, the drug solution Q supplied by the drug solution supply device 1 of the present invention is appropriately selected according to the purpose of use. For example, analgesics such as morphine (narcotic analgesics), insulin preparations, antibiotics, etc. , Anticancer agents, and narcotic agents. Note that the type of the drug solution Q is not limited to this, and includes, for example, those that do not exert direct effects such as physiological saline, electrolytic water, cleaning solution, anticoagulant, and contrast agent.

Next, the operation of the chemical solution supply tool 1 will be described. First, the microinjection of the drug solution Q will be described.

[0082] When injecting a small amount of the drug solution Q, the grip portion 93 is gripped and the operation dial 91 is rotated, so that the third state shown in FIG. 4 (the state where the tip of the pin 97 is inserted into the recess 96b) ), The first state shown in FIG. 5 (the state where the tip of the pin 97 is inserted into the recess 96a) or the second state shown in FIG. 6 (the state where the tip of the pin 97 is inserted into the recess 96c) ), And the upstream force of the tube 14 also supplies the chemical Q. After a predetermined time has elapsed, the chamber 31 is filled with the chemical Q and primed (filled).

[0083] When the operation dial 91 is set to the third state (reference position), the drug solution Q that has passed through the tube 14 is diverted by the Y-shaped connector 13, and the first tube 10a and the second tube It flows through each tube 10b and flows into the chamber 31 through the inlets 32a and 32b. As a result, approximately the same amount of the drug Q stored in the chamber 31 flows out from the outlet 33 and is sent downstream through the one-way valve 16 and the tube 17 to be administered to the patient. Is done. At this time, the flow rate of the chemical liquid Q flowing out from the outlet 33 is V (= V +

3 1

V).

2

[0084] When the operation dial 91 is set to the first state, the chemical Q from the tube 14 flows through the second tube 10b through the Y-shaped connector 13, and passes through the inlet 32b to the chamber 31. Flows in. As a result, the drug solution Q force outflowing from the outlet 33, which has been stored in the chamber 31 of approximately the same amount as the inflow, is sent to the downstream via the one-way valve 16 and the tube 17, and is administered to the patient. Is done. At this time, the flow rate of the chemical liquid Q flowing out from the outlet 33 is V.

2

[0085] When the operation dial 91 is set to the second state, the chemical Q from the tube 14 flows through the first tube 10a via the Y-shaped connector 13, and passes through the inlet 32a to the chamber 31. Flows in. As a result, the drug solution Q force outflowing from the outlet 33, which has been stored in the chamber 31 of approximately the same amount as the inflow, is sent to the downstream via the one-way valve 16 and the tube 17, and is administered to the patient. Is done. At this time, the flow rate of the chemical liquid Q flowing out from the outlet 33 is V.

[0086] As described above, the flow rate of the drug solution Q to be injected and administered is set to V, V <V

1, V

2, V (these are

3 1 2

<V satisfies the relationship of V). [0087] Now, the tube of the present invention having the constant temperature flow rate function as described below can be employed in at least one of the first tube 10a and the second tube 10b. Here, a case where the tube of the present invention is applied (adopted) to the second tube 10b will be described, and the tube of the present invention will be described in detail based on a preferred embodiment shown in the accompanying drawings.

[0088] <First embodiment>

FIG. 7 is a perspective view showing the first embodiment of the tube (second tube) of the present invention, and FIGS. 8 and 9 are views when the second tube shown in FIG. 7 is deformed by a temperature change, respectively. FIG.

[0089] The second tube 10b includes a tube main body 12 in which a flow path l ib through which the chemical liquid Q can pass is formed at a downstream side thereof, and a regulating member 19 that regulates the outer diameter of the tube main body 12. (See Fig. 4 and Fig. 7).

[0090] The restricting member 19 has a substantially ring-shaped cross section, and is fixed (provided) to the downstream side portion of the tube body 12 (see FIGS. 4 and 7). The restricting member 19 is made of a material having a coefficient of thermal expansion S smaller than that of the tube body 12.

[0091] In the second tube 10b, the cross-sectional area of the flow path 1 lb changes (increased Z decreases) as the tube body 12 expands and contracts due to temperature changes at the portion where the regulating member 19 is provided. The Hereinafter, this “cross-sectional area increases Z decreases” is referred to as “channel l ib increases in diameter Z decreases in diameter”.

[0092] When the temperature rises, the tube body 12 tries to expand outward (in the direction of the arrow toward the outside of the tube body 12 in Fig. 8), but the outer periphery (outer side) of the tube body 12 is restricted. It is regulated by the material 19, and the tube body 12 cannot expand outward. For this reason, the tube main body 12 expands toward the center side (the direction of the arrow toward the inside of the tube main body 12 in FIG. 8). Therefore, the diameter of the flow path l ib is reduced.

[0093] On the other hand, when the temperature is lowered, the diameter of the channel 1 lb is increased, contrary to the above.

Assuming that the diameter of the flow channel l ib does not change (constant), the viscosity of the chemical solution Q decreases as the temperature rises, and the resistance of the chemical solution Q flowing in the flow channel l ib decreases. When a certain pressure difference is generated at both ends of the main body 12, the flow rate of the chemical Q increases.

[0094] On the other hand, when the temperature decreases, in the case of the same pressure difference as described above, the flow of the chemical solution Q is reversed. The amount is too small.

[0095] Therefore, in the tube of the present invention, when the temperature rises, the flow path ib decreases in diameter so as to offset the increase in the flow rate of the chemical solution Q due to the decrease in the viscosity of the chemical solution Q. On the other hand, when the temperature decreases, the flow path ib expands so as to offset the decrease in the flow rate of the chemical solution Q due to the increase in the viscosity of the chemical solution Q.

[0096] With the configuration as described above, the flow rate of the chemical liquid Q passing through the flow path ib can be made constant regardless of the temperature change. That is, it is possible to prevent the flow rate of the chemical liquid Q passing through the flow path l ib from changing due to a temperature change. Hereinafter, a state in which the flow rate of the chemical solution Q is constant regardless of temperature changes is referred to as an “equilibrium state”.

[0097] Further, for example, when an analgesic such as morphine is administered (injected) to a patient, a minute injection is required. Therefore, administration of the dose (flow rate per unit time) must be very strict. The tube of the present invention is also very suitable for such a case.

[0098] Further, the present invention is not limited to applying the tube of the present invention only to the second tube 10b. For example, it is more preferable to apply the tube of the present invention to each of the first tube 10a and the second tube 10b.

[0099] Examples of the constituent material of the tube body 12 include various types of plastics such as soft polysalt cellulose, polyethylene, polyurethane, and polybutadiene, natural rubber, styrene butadiene rubber, and isoprene rubber. Those which are easily expanded and contracted by change are preferred.

[0100] It is preferable that the regulating member 19 is mainly composed of a metal material. Examples of the metal material include various metals such as iron, nickel, stainless steel, copper, brass, aluminum, and titanium. Or alloys containing these, and plastics that have low expansion and contraction due to temperature changes and high rigidity.

Thereby, the regulating member 19 having a smaller coefficient of thermal expansion than that of the tube main body 12 can be formed (configured).

[0102] The method for fixing the tube main body 12 and the regulating member 19 is not particularly limited. For example, the tube main body 12 and the regulating member 19 can be fixed by bonding with an adhesive. This makes the tube book When the body 12 contracts, the tube main body 12 and the regulating member 19 can be prevented from being separated from each other, so that the diameter of the flow path rib can be reliably increased. Further, the thickness of the adhesive layer is preferably thin.

[0103] <Second Embodiment>

FIG. 10 is a perspective view showing a second embodiment of the tube (second tube) of the present invention.

[0104] Hereinafter, the second embodiment of the tube of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

This embodiment is the same as the first embodiment except that the configuration (installation state) of the restricting member is different.

As shown in FIG. 10, a plurality of regulating members 19A are provided at intervals (intermittently) along the longitudinal direction of the tube body 12. The restricting member 19A has a cylindrical shape with a predetermined length.

[0106] By providing (forming) such a configuration, that is, by providing (forming) a portion (part) where there is no portion restricted by the restricting member 19A, the ratio of the diameter of the channel l ib to the Z contraction (hereinafter referred to as "correction Rate)). As a result, the correction factor can be set more appropriately by appropriately adjusting the number (number of installations) of the regulating members 19A, the size of the interval between the neighboring regulating members 19A, etc. 2Tube 10b can be brought closer to equilibrium.

[0107] Further, the tube body 12 can be easily bent, and thus the second tube 10b can be easily (compactly) stored (installed) in the chemical solution supply tool 1.

FIG. 11 is a perspective view showing a third embodiment of the tube (second tube) of the present invention.

[0109] Hereinafter, the second embodiment of the tube of the present invention will be described with reference to this figure. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

[0110] This embodiment is the same as the first embodiment except that the configuration of the tube body is different.

[0111] As shown in Fig. 11, the tube main body 12A is provided on the inner layer 121 and on the outer peripheral side of the inner layer 121. The laminated portion 123A having the outer layer 122 is provided. The laminated portion 123A is formed over substantially the entire length of the second tube 10b (tube body 12A) in the longitudinal direction.

[0112] The inner layer 121 is made of a material that is more inert to the chemical Q.

The outer layer 122 is made of a material having an appropriate coefficient of thermal expansion in order to maintain an equilibrium state. The coefficient of thermal expansion is preferably larger than the coefficient of thermal expansion of the inner layer 121.

The regulating member 19 is provided over almost the entire length of the outer layer 122 in the longitudinal direction.

[0113] With such a configuration, the correction factor can be set more appropriately, and thus the second tube 10b can be brought closer to an equilibrium state.

[0114] <Fourth embodiment>

FIG. 12 is a perspective view showing a fourth embodiment of a tube (second tube) of the present invention.

[0115] Hereinafter, a fourth embodiment of the tube of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

[0116] This embodiment is the same as the third embodiment, except that the configuration of the laminated portion is different.

As shown in FIG. 12, the laminated portion 123B of the tube body 12B is provided (formed) on a part of the tube body 12B. The outer layer 122 of the laminated portion 123B is filled (injected) with a liquid material having a higher thermal expansion coefficient than the inner layer 121 in a gap formed between the outer peripheral surface of the inner layer 121 and the inner peripheral surface of the regulating member 19. It is formed by solidifying.

[0117] With such a configuration, the correction factor can be set more appropriately by appropriately adjusting the length, outer diameter, constituent material, and the like of the outer layer 122. Accordingly, the second tube 10b can be more appropriately configured. It can approach the equilibrium state.

[0118] The liquid material includes, for example, epoxy resin, water, oil, various gel materials, and those in which bubbles are mixed.

[0119] While the tube and the liquid supply device of the present invention have been described based on the illustrated embodiments, the present invention is not limited to them. For example, the configuration of each part exhibits the same function. Any possible configuration can be substituted.

[0120] Further, the tube is not limited to being used in a liquid supply tool as shown in FIG. For example, you may use for an infusion bag etc.

Example

Next, specific examples of the present invention will be described.

1. Preparation of tube

[0122] (Example)

A tube having the structure shown in FIG. 10 was produced. The specification of this tube is shown below.

[0123] Constituent material of the tube body: Polyvinyl chloride

Tube body length: 31mm

Tube body outer diameter: 1.5 mm

Inner diameter of tube body: 0.06mm (25 ° C)

Regulatory component material: Stainless steel

Number of restriction members formed (number of installations): 4

Length per regulating member: 3mm

Regulating member outer diameter: 1.8 mm

Inner diameter of regulating member: 1.6 mm

Spacing between each regulating member: 5mm

[0124] (Comparative example)

The restriction member was removed from the tube of the above example! /, And a tube with only the (deleted) tube body was produced.

[0125] 2. Evaluation

Next, the flow rate was measured when water having a constant pressure applied to one end side through each flow path of the tube of the example and the tube of the comparative example while changing the temperature.

[0126] Fig. 13 shows the result. FIG. 13 is a graph showing the relationship between the temperature and the flow rate of water passing through the tube.

[0127] As shown in Fig. 13, the tube of the example has a smaller width of the change in the water flow rate due to the temperature change than the tube of the comparative example. Therefore, it was confirmed that the tube of the example can keep the flow rate of water as constant as possible regardless of the temperature change.

[0128] In addition, tubes having the structures shown in Figs. 7, 11, and 12 were produced, respectively. When the evaluation was performed in the same manner as in the examples, the same results as in the above examples were obtained. Industrial applicability

The tube of the present invention is a tube through which a liquid passes. A tube body in which a liquid can pass is formed, and expands and contracts due to a temperature change, and at least a part of the tube body in the longitudinal direction. And a regulating member that regulates the outer diameter of the tube main body, and in the portion where the regulating member is provided, the tube main body expands due to the temperature change. To do. Therefore, the flow rate of the liquid passing through the flow path can be made constant regardless of the temperature change. That is, it is possible to prevent the flow rate of the liquid passing through the flow path from changing due to temperature change. Therefore, the tube of the present invention has industrial applicability.

Claims

The scope of the claims

[I] A tube through which liquid passes,

A tube characterized in that the cross-sectional area of the flow path changes as the tube body expands and contracts due to the temperature change at a portion where the regulating member is provided.

[2] The extent of expansion and contraction of the tube body due to the temperature change is set so that the flow rate of the liquid becomes constant when the liquid passes through the flow path. Tube as described in.

[3] The tube according to claim 1, wherein the regulating member has a smaller coefficient of thermal expansion than the tube body.

[4] The tube according to claim 1, wherein the restricting member is provided over substantially the entire length in the longitudinal direction of the tube body.

[5] The tube according to claim 1, wherein a plurality of the regulating members are provided at intervals along the longitudinal direction of the tube body.

[6] The tube body includes a laminated portion having an inner layer and an outer layer provided on the outer peripheral side of the inner layer and made of a material different from the inner layer,

The tube according to claim 1, wherein the regulating member is provided on an outer peripheral side of the outer layer.

7. The tube according to claim 6, wherein the outer layer has a larger coefficient of thermal expansion than the inner layer.

[8] The tube according to claim 1, wherein the regulating member has a substantially ring-shaped cross section.

[9] The tube according to claim 1, wherein the restriction member is mainly made of a metal material.

10. The tube according to claim 1, wherein the liquid is a chemical solution administered into a living body.

[II] It has the tube according to any one of claims 1 to 10 and has a liquid flow rate.