WO2006113227A3 - Compositions facilitating drug penetration and drug retention in skin - Google Patents

Compositions facilitating drug penetration and drug retention in skin Download PDF

Info

Publication number
WO2006113227A3
WO2006113227A3 PCT/US2006/013496 US2006013496W WO2006113227A3 WO 2006113227 A3 WO2006113227 A3 WO 2006113227A3 US 2006013496 W US2006013496 W US 2006013496W WO 2006113227 A3 WO2006113227 A3 WO 2006113227A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
skin
retention
penetration
compositions facilitating
Prior art date
Application number
PCT/US2006/013496
Other languages
French (fr)
Other versions
WO2006113227A2 (en
Inventor
Biancamaria Baroli
Original Assignee
Massachusetts Inst Technology
Biancamaria Baroli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Biancamaria Baroli filed Critical Massachusetts Inst Technology
Publication of WO2006113227A2 publication Critical patent/WO2006113227A2/en
Publication of WO2006113227A3 publication Critical patent/WO2006113227A3/en
Priority to IL186634A priority Critical patent/IL186634A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to delivery systems comprising a saturating agent and a lipophilic or hydrophilic agent in solution in a polar solvent, a surfactant or an organic solvent and methods of use thereof. The systems and methods of this invention find application in transdermal drug delivery, for the treatment of local and systemic diseases, disorders and/or conditions.
PCT/US2006/013496 2005-04-13 2006-04-11 Compositions facilitating drug penetration and drug retention in skin WO2006113227A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL186634A IL186634A0 (en) 2005-04-13 2007-10-14 Compositions facilitating drug penetration and drug retention in skin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67064105P 2005-04-13 2005-04-13
US60/670,641 2005-04-13

Publications (2)

Publication Number Publication Date
WO2006113227A2 WO2006113227A2 (en) 2006-10-26
WO2006113227A3 true WO2006113227A3 (en) 2007-02-22

Family

ID=37115666

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/013496 WO2006113227A2 (en) 2005-04-13 2006-04-11 Compositions facilitating drug penetration and drug retention in skin

Country Status (2)

Country Link
IL (1) IL186634A0 (en)
WO (1) WO2006113227A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125816B2 (en) 2000-08-30 2015-09-08 Besins Healthcare Inc. Pharmaceutical composition and method for treating hypogonadism

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1970051A1 (en) * 2007-03-14 2008-09-17 Merz Pharma GmbH & Co.KGaA Use of an aqueous micro-emulsion for the preparation of a formulation for the treatment of adipose diseases
EP2666456A1 (en) 2012-05-21 2013-11-27 Natura Bisse International, S.A. Cometic compositions comprising magnetosomes and uses thereof
GB201620701D0 (en) * 2016-12-06 2017-01-18 Glaxosmithkline Consumer Healthcare (Uk) Ip Ltd Novel composition
DE102018113509A1 (en) 2018-06-06 2019-12-12 Philipps-Universität Marburg Microemulsion for dermal hyposensitization with allergens

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030161870A1 (en) * 1999-12-16 2003-08-28 Tsung-Min Hsu Dual enhancer composition for topical and transdermal drug delivery
US20030170308A1 (en) * 2001-05-01 2003-09-11 Cleary Gary W. Hydrogel compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030161870A1 (en) * 1999-12-16 2003-08-28 Tsung-Min Hsu Dual enhancer composition for topical and transdermal drug delivery
US20030170308A1 (en) * 2001-05-01 2003-09-11 Cleary Gary W. Hydrogel compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125816B2 (en) 2000-08-30 2015-09-08 Besins Healthcare Inc. Pharmaceutical composition and method for treating hypogonadism
US9132089B2 (en) 2000-08-30 2015-09-15 Besins Healthcare Inc. Pharmaceutical composition and method for treating hypogonadism

Also Published As

Publication number Publication date
IL186634A0 (en) 2008-01-20
WO2006113227A2 (en) 2006-10-26

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