WO2006109175A3 - Solid dosage form of an antidiabetic drug - Google Patents

Solid dosage form of an antidiabetic drug Download PDF

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Publication number
WO2006109175A3
WO2006109175A3 PCT/IB2006/001007 IB2006001007W WO2006109175A3 WO 2006109175 A3 WO2006109175 A3 WO 2006109175A3 IB 2006001007 W IB2006001007 W IB 2006001007W WO 2006109175 A3 WO2006109175 A3 WO 2006109175A3
Authority
WO
WIPO (PCT)
Prior art keywords
solid dosage
antidiabetic drug
dosage form
dosage forms
relates
Prior art date
Application number
PCT/IB2006/001007
Other languages
French (fr)
Other versions
WO2006109175A2 (en
Inventor
Venkata Rama Rao Kamala
Srinivasa Rao Shaik
Ashish Gogia
Sivakumaran Meenakshisunderam
Original Assignee
Aurobindo Pharma Ltd
Venkata Rama Rao Kamala
Srinivasa Rao Shaik
Ashish Gogia
Sivakumaran Meenakshisunderam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurobindo Pharma Ltd, Venkata Rama Rao Kamala, Srinivasa Rao Shaik, Ashish Gogia, Sivakumaran Meenakshisunderam filed Critical Aurobindo Pharma Ltd
Publication of WO2006109175A2 publication Critical patent/WO2006109175A2/en
Publication of WO2006109175A3 publication Critical patent/WO2006109175A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

The present invention relates to solid dosage forms of an antidiabetic drug glyburide. More particularly, the present invention relates to solid dosage forms of antidiabetic drug glyburide with specific particle size and specific surface area.
PCT/IB2006/001007 2005-04-11 2006-04-10 Solid dosage form of an antidiabetic drug WO2006109175A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN403CH2005 2005-04-11
IN403/CHE/2005 2005-04-11

Publications (2)

Publication Number Publication Date
WO2006109175A2 WO2006109175A2 (en) 2006-10-19
WO2006109175A3 true WO2006109175A3 (en) 2007-02-08

Family

ID=37087398

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/001007 WO2006109175A2 (en) 2005-04-11 2006-04-10 Solid dosage form of an antidiabetic drug

Country Status (1)

Country Link
WO (1) WO2006109175A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
EP3763419A1 (en) 2011-01-07 2021-01-13 Anji Pharma (US) LLC Chemosensory receptor ligand-based therapies
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
NZ626578A (en) 2012-01-06 2016-11-25 Elcelyx Therapeutics Inc Compositions and methods for treating metabolic disorders
JP2015503582A (en) 2012-01-06 2015-02-02 エルセリクス セラピューティクス インコーポレイテッド Biguanide compositions and methods of treating metabolic disorders

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979520A (en) * 1973-09-26 1976-09-07 Boehringer Mannheim G.M.B.H. Preparation of rapidly resorbable glibenclamide
US4060634A (en) * 1973-09-26 1977-11-29 Boehringer Mannheim G.M.B.H. Rapidly resorbable glibenclamide
WO2001051463A1 (en) * 2000-01-14 2001-07-19 Bristol-Myers Squibb Company Glyburide composition
US20050260273A1 (en) * 2001-06-07 2005-11-24 Chinea Vanessa I Applicatin of a bioactive agent in a solvent composition to produce a target particle morphology

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979520A (en) * 1973-09-26 1976-09-07 Boehringer Mannheim G.M.B.H. Preparation of rapidly resorbable glibenclamide
US4060634A (en) * 1973-09-26 1977-11-29 Boehringer Mannheim G.M.B.H. Rapidly resorbable glibenclamide
WO2001051463A1 (en) * 2000-01-14 2001-07-19 Bristol-Myers Squibb Company Glyburide composition
US6830760B2 (en) * 2000-01-14 2004-12-14 Bristol-Myers Squibb Company Glyburide composition
US20050260273A1 (en) * 2001-06-07 2005-11-24 Chinea Vanessa I Applicatin of a bioactive agent in a solvent composition to produce a target particle morphology

Also Published As

Publication number Publication date
WO2006109175A2 (en) 2006-10-19

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