WO2006097349A1 - Usage cosmetique d’un materiau microporeux solide cristallin (monoxyde d’azote) pour ameliorer la coloration et/ou l’apparence naturelle de la peau et/ou des levres - Google Patents

Usage cosmetique d’un materiau microporeux solide cristallin (monoxyde d’azote) pour ameliorer la coloration et/ou l’apparence naturelle de la peau et/ou des levres Download PDF

Info

Publication number
WO2006097349A1
WO2006097349A1 PCT/EP2006/002660 EP2006002660W WO2006097349A1 WO 2006097349 A1 WO2006097349 A1 WO 2006097349A1 EP 2006002660 W EP2006002660 W EP 2006002660W WO 2006097349 A1 WO2006097349 A1 WO 2006097349A1
Authority
WO
WIPO (PCT)
Prior art keywords
agents
lips
skin
use according
zeolite
Prior art date
Application number
PCT/EP2006/002660
Other languages
English (en)
Inventor
Marie-Madeleine Cals-Grierson
Original Assignee
L'oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0550658A external-priority patent/FR2883163B1/fr
Application filed by L'oreal filed Critical L'oreal
Publication of WO2006097349A1 publication Critical patent/WO2006097349A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A61Q1/06—Lipsticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/0229—Sticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/28—Zirconium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/10—Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/87—Application Devices; Containers; Packaging
    • A61K2800/872—Pencils; Crayons; Felt-tip pens

Definitions

  • the field of the invention relates to the ' care and/or the natural make-up of the skin, contour of the eye and/or lips.
  • the invention relates in particular- to the cosmetic use in a composition of at least one microporous solid- crystal-line material comprising releasable adsorbed nitrogen monoxide NO as agent intended to improve the colour of the skin and/or of the lips and/or the appearance of the lips.
  • Reference' will be made in particular to natural make-up of the skin and/or lips.
  • the said NO adsorbed i ' n the microporous crystalline material which can be released when the composition is applied to the skin and/or lips is , intended to restore fullness to the lips and/or to promote their naturally pink colouring, to improve the appearance of the complexion (good look effect) and/or to reduce periocular lines.
  • the invention also relates to compositions comprising at least one zeolite comprising releasable adsorbed NO and at least one specific cosmetic active agent and to a cosmetic process for beautifying the skin and/or lips employing the said compositions.
  • natural make-up is understood to mean, according to the invention, a means which makes it possible to naturally improve the aesthetic appearance of the skin and/or lips, in contrast to conventional make-up, which employs make-up agents of dye, pigment and/or filler type which confer an optical effect of colouring and/or of volume intended to conceal the imperfections of the skin and/or to emphasize certain areas of the face.
  • make-up agents of dye, pigment and/or filler type which confer an optical effect of colouring and/or of volume intended to conceal the imperfections of the skin and/or to emphasize certain areas of the face.
  • the aim in particular in cosmetics is to promote the clearness and/or the radiance of the complexion and/or to reduce its muddy or waxy appearance and/or to confer a good look effect thereon. This is particularly interesting to people who are not exposed to the sun or are only slightly exposed to the sun.
  • the prior art teaches, for example, the use in cosmetics of dihydroxyacetone, or DHA, or the use of self-tanning agents for promoting the artificial colouring of the skin.
  • Lines around the eyes and bags are regarded as unattractive and attempts have always been made to mask them, indeed even to remove them.
  • the formation of "lines around the eyes” is due in particular to a slowdown in the microcirculation of the blood, in particular during the night, resulting in an accumulation of blood pigments in the connective tissue, visible in particular on getting up in the morning.
  • the lymphatic system which has also slowed down during the night, results in distension of the eyelids. This distension, in combination with the slackening of the tissues related to age, brings about the formation of the "bags".
  • the aim is thus to reduce periocular lines and/or bags in order to obtain a complexion which is more homogeneous over the entire face.
  • make-up products for example: foundation
  • make-up products for example: foundation
  • these compositions can sometimes give a powdery, indeed even chalky, matt appearance to the skin which can accentuate the defects of the skin.
  • thin lips in particular in women, are also regarded as unattractive.
  • women have resorted in particular to cosmetic surgery, injection or tattooing techniques and there is a tendency for the use of these techniques to spread, including to women with normal lips who want full or fleshy lips.
  • these techniques are expensive, in some cases can give an irreversible result (for example: cosmetic surgery, tattooing) or in other cases can result in side effects of infection or allergy (for example: collagen injection, tattooing, and the like).
  • Patent Application EP 1 382 323 for the use, in a composition for the lips, of at least one goniochromatic colouring agent capable of creating a goniochromatic coloured background which changes according to the angle of observation and/or of incidence of the light, in combination with reflecting particles capable of creating, when the composition is applied to the lips, highlight points which create an optical effect of volume or an effect of fullness.
  • the Applicant Company proposes to use, in a cosmetic composition, a microporous solid crystalline material comprising releasable adsorbed nitrogen monoxide NO in order to meet this expectation.
  • the microporous solid crystalline material is a zeolite comprising releasable adsorbed NO.
  • Nitrogen monoxide is known to be involved in numerous biological processes, in particular in the immune system, and has numerous interactions with nucleic acids, proteins, low molecular weight thiols, and the like.
  • the Applicant Company has already provided for the use of NO donors or precursors in cosmetic or dermatological compositions in the fields of the vascularization of the skin or mucous membranes, of the regulation of the growth of bacteria, of the prevention of damage caused by UV radiation, of slimming, of antiageing, and the like. Due to its gaseous state, NO additionally exhibits the advantage of easily diffusing through the skin or lips or into the surface layers of the skin or lips, making it possible to rapidly obtain the desired effect.
  • zeolites in the chemical industry; they are used in particular as adsorbents or desiccants in the drying of fluids (gases) , as industrial catalysts in the fields of oil refining or petrochemical production, or as agents which are substitutes for phosphates in washing powders.
  • Application WO 2005/003032 discloses zeolites comprising releasable adsorbed NO and suggests their use in pharmaceutical compositions intended for the treatment of skin diseases, as well as in hygiene compositions (deodorants, depilatory preparations) or in antiageing cosmetic compositions.
  • the invention thus relates in particular to the cosmetic use in a composition of at least one microporous solid crystalline material comprising releasable adsorbed nitrogen monoxide NO as agent intended to improve the colour of the skin and/or lips and/or the appearance of the lips.
  • a composition of at least one microporous solid crystalline material comprising releasable adsorbed nitrogen monoxide NO as agent intended to improve the colour of the skin and/or lips and/or the appearance of the lips.
  • natural make-up is understood to mean, according to the invention, an aesthetic improvement in the skin and/or lips employing, as active agent, nitrogen monoxide intended to naturally promote, that is to say without the necessary addition of make-up agents with a volume-enhancing or colouring optical effect, the colouring and/or the increase in volume of the skin and/or lips.
  • This natural make-up is also regarded, according to the invention, as a “care make-up” .
  • the said NO adsorbed in the microporous crystalline material which can be released when the composition is applied to the skin and/or lips is intended in particular to: restore fullness to the lips, that is to say to increase their size, their volume and/or their thickness and/or to give them a more swollen or fleshy appearance and/or to model them and/or to render them smoother and/or to stimulate the naturally pink colouring of the lips; stimulate the naturally pink colouring of the skin and/or to confer a good natural look effect on the skin; homogenize the complexion and/or to promote its lustre and/or its radiance and/or to reduce the muddy or waxy complexion effect; - reduce bags and/or to lighten lines around the eyes and/or to render the complexion of the area of the lines around the eyes uniform with the remainder of the face.
  • microporous solid crystalline material according to the invention is understood to mean in particular an organic, inorganic or hybrid solid crystalline material.
  • the material is solid at atmospheric pressure and at a temperature of less than approximately 40 0 C.
  • the solid crystalline material is microporous.
  • the size of the pores is generally less than 1 micron, preferably less than or equal to
  • the pores can form a repeating three- dimensional network capable of trapping the nitrogen monoxide or a complex of nitrogen monoxide with an inorganic cation or an organic cation.
  • microporous solid crystalline materials which can be used according to the invention, of zeotypes and zeolites.
  • zeolites the general formula of which is represented in the oxide form by IMb n O*A1 2 U3' xSiC>2* yf ⁇ O, in which n is the valency of the cation M, x is the number of silica molecules and y is the number of molecules of water of crystallization.
  • Zeolite materials constitute a class of aluminosilicate materials which are known and used in various applications, for example ion exchange, gas separation and catalysis (A. Dyer, An Introduction to Zeolite Molecular Sieves, J. Wiley and Sons, 1988).
  • Zeolites can be of natural origin or can be prepared synthetically. Zeolites are nanoporous crystalline aluminosilicate structures composed of AlO 4 and SiO 4 tetrahedra connected to one another via oxygen vertices. Assembling the tetrahedra in space forms polyhedra which delimit a network of 1-, 2- or 3- dimensional channels, cages and cavities in which cations are positioned at points' where they balance the negative charges carried by the AlO 4 " tetrahedra. The size and the arrangement of the tetrahedra differentiate the zeolites.
  • the zeolite can be represented by the general formula Al y Sii- y O 4 y ⁇ .
  • Zeolites can comprise transition element cations as extraframework entity, for example iron, copper or ruthenium, and nitrogen monoxide forms complexes inside the cavities of the zeolite material.
  • Cations of other elements bind nitrogen monoxide less strongly.
  • a person skilled in the art can use standard ion exchange processes to introduce the required metal ions into a zeolite structure as extraframework cations (Plank et al., US Patent No. 3 140 249; Preparation, Characterisation and Performance of Fe-ZSM-5 Catalysts, R. Joyner and M. Stockenhuber, J. Phys . Chem. B., 1999, 103, 5963-5976) . By using such techniques, it is possible to incorporate mixtures of cations in zeolite structures.
  • Zeolites can be in the dehydrated state.
  • the amount of nitrogen monoxide charged to the zeolites can be controlled by varying the relative amounts of the extraframework cations, by controlling their chemical nature and/or the total number of cations present.
  • the number of extraframework cations present in the zeolite structure can depend on the amount of aluminium present in the framework. More aluminium ions require more extraframework cations to balance the negative charge.
  • the chemical nature of the extraframework cations can also be modified (for example, monovalent cations, for example Na + and Ag + , can be exchanged by divalent cations, for example Fe 2+ and Cu 2+ , or trivalent cations, for example Ru 3+ and Fe 3+ ) .
  • Each different cation can have a different affinity for NO and changing the cations present in the zeolite framework can be used to control the release of NO.
  • Such an adjustment of the zeolite composition can affect the kinetics under which the nitrogen monoxide is released.
  • a sodium-loaded zeolite can bind nitrogen monoxide less strongly than an iron-loaded zeolite and can release the nitrogen monoxide more rapidly.
  • a sodium/iron mixed zeolite can release the nitrogen monoxide at a different rate from a sodium-loaded zeolite or from an iron-loaded zeolite and such a release of nitrogen monoxide can exhibit a different rate profile.
  • the zeolite framework can also be chosen in order to vary the rate of release of the nitrogen monoxide.
  • Zeolite frameworks are available in the form of synthetic materials having different structures (Atlas of Zeolite Framework Types, Fifth Revised Edition, Ch. Baerlocher, W. M. Meier, D. H Olson, 2001, Elsevier) .
  • the size of the pores and of the channels of the zeolite framework can be varied.
  • the zeolite having the LTA structure has openings defined by 8 pore tetrahedral units (that is to say, a ring of 8 Si/Al atoms and 8 oxygen atoms) .
  • Zeolite MFI has a bigger ring opening defined by 10 tetrahedral units and FAU by an even bigger pore opening of 12 tetrahedral units.
  • the configuration of the pores in space can also differ from one zeolite to another.
  • some zeolites have channels which extend in only one direction (one-dimensional channel systems) , while others have systems of channels which interact in two or three dimensions (2-dimensional or 3-dimensional channel systems) .
  • the size, the shape and the configuration in space of zeolites can affect the rates of diffusion and of adsorption/desorption of the nitrogen monoxide (NO) and can be used to control the rate of release of NO.
  • NO nitrogen monoxide
  • the composition of the zeolite material can be adjusted so as to control the amount of nitrogen monoxide charged to the zeolite structure and/or the rate at which the nitrogen monoxide is released from the zeolite.
  • Such zeolite structures can be chosen, without being limited thereto, from the frameworks having the following three-letter codes: LTA, FAU, MFI, MOR, FER, BEA, PEI and SAS (see the website of the International Zeolite Association, www. iza-online . org, for further details on the correspondence between the codes and the framework structures of the zeolites) .
  • These three-letter codes describe the framework architecture of the zeolites, that is to say their structure, but they do not describe the composition of the zeolite, which can vary greatly.
  • the three-letter codes are used as nomenclature systems for zeolites.
  • Zeolites can be prepared by ion exchange according to the method described in the work Verified Synthesis of Zeolitic Materials, Robson H. and Lillerud K. P., Verified Synthesis of Zeolitic Materials, 2nd Revised Edition, International Zeolite Association, 2001, www. iza-synthesis . org.
  • the zeolites Before charging with nitrogen monoxide, the zeolites can be completely or partially dehydrated, for example under vacuum, to remove water from the zeolite channels. The resulting zeolite can subsequently be exposed to nitrogen monoxide.
  • charging with nitrogen monoxide is carried out at a temperature of -100 0 C to 5O 0 C.
  • Charging with nitrogen monoxide can be carried out with pure NO or with a mixture of NO and of a carrier gas, such as an inert gas, for example helium, argon or another inert gas, including mixtures of these.
  • Charging is typically carried out at a pressure between atmospheric pressure and a pressure of 10 bar.
  • Nitrogen monoxide begins to be released when the cosmetic composition is applied to the skin and/or lips.
  • the zeolite charged with nitrogen monoxide can be prepared in the powder or monolith form.
  • the monoliths can be formed by compressing a zeolite powder or by mixing a pulverulent zeolite with an appropriate binder.
  • Appropriate binders comprise, without being limited thereto, ceramic binders, for example silica or alumina, and polymeric binders, for example polysulphone, polyethylene, PET, polystyrene, poly- tetrafluoroethylene (PTFE) and other polymers.
  • a zeolite comprising releasable adsorbed NO of general formula (I) :
  • z is the number of silicon atoms replaced by aluminium atoms in the zeolite framework
  • n+, p+ and q+ are independently integers 1+, 2+ or 3+ when the associated cation is a metal cation or equal to 1+ when the associated cation is an organic cation, in a cosmetic composition as agent intended to improve the appearance and/or the colour of the skin and/or lips, in particular to promote the natural make-up of the skin, contour of the eye and/or lips.
  • NH 4 + is preferable.
  • the zeolite can have the general formula
  • Mi and M 2 are extraframework metal cations of elements chosen from Zn or Mn, more preferably still Zn.
  • the NO adsorbed in the zeolites of formula (I) and (II) which can be released when the composition is applied to the skin and/or lips will be intended in particular to: - restore fullness to the lips, that is to say to increase their size, their volume and/or their thickness and/or to give them a more swollen or fleshy appearance and/or to model them and/or to render them smoother and/or to stimulate the naturally pink colouring of the lips; stimulate the naturally pink colouring of the skin and/or to confer a good natural look effect on the skin; homogenize the complexion and/or to promote its lustre and/or its radiance and/or to reduce the muddy or waxy complexion effect; reduce bags and/or to lighten lines around the eyes and/or to render the complexion of the area of the lines around the eyes uniform with the remainder of the face.
  • the zeotype can be silicalite (see the article by C. Lamberti, S. Bordiga and A. Zecchina which appeared in the review Rassegna Scientifica, Vol. 4, No. 2, December 1999, the content of which is incorporated in the present application by reference) .
  • Patent Applications US 4 480 135 and US 5 110 995 Processes for the preparation of titanium and iron zeotypes are disclosed respectively in Patent Applications US 4 480 135 and US 5 110 995.
  • Patent Application US 5 110 995 discloses the preparation of an iron zeotype from a mixture comprising a source of silica, a source of iron and, if necessary, a source of El n+ (where El is an element from Periods 2, 3, 4 or 5 of the Periodic Table of the Elements) , a base, an organic surfactant and optionally a crystallization seed.
  • the said microporous solid crystalline material comprising releasable adsorbed NO is present in the composition in a sufficient amount such that the amount of NO which can be released when the composition is applied to the skin and/or lips is effective in producing the desired effect, namely an effect on the natural colouring of the skin (good look effect) , an effect on the colouring and/or volume of the lips or an effect on the contour of the eye (concealers and/or products for treating bags) .
  • the effect on the complexion, lines around the eyes or lips can be directly measured by simple visual observation or by comparative image analysis.
  • the said zeolite will be present in the composition in an amount such that the amount of NO which can be released on contact with keratinous substances is from 0.001 to 10% by weight with respect to the total weight of the composition, preferably from 0.01 to 5%, better still from 0.01 to 2% and even better still from 0.02 to 1% by weight, with respect to the total weight of the composition.
  • the zeolite will be present in the composition in an amount ranging from 0.01 to 20% by weight with respect to the total weight of the composition, preferably between 0.1 and 10% by weight, with respect to the total weight of the composition.
  • microporous solid crystalline materials comprising releasable adsorbed NO present in the compositions according to the invention can be combined with at least one cosmetic agent chosen from fillers, colouring materials, hydrophilic or lipophilic active agents, thickeners, emulsifiers, hydrophilic or lipophilic gelling agents, surfactants, moisturizing agents, softening agents, sequestering agents, fragrances, neutralizing agents, preservatives, antioxidants, UV screening agents, bactericides, trace elements, odour absorbers and pH adjusters, and their mixtures .
  • at least one cosmetic agent chosen from fillers, colouring materials, hydrophilic or lipophilic active agents, thickeners, emulsifiers, hydrophilic or lipophilic gelling agents, surfactants, moisturizing agents, softening agents, sequestering agents, fragrances, neutralizing agents, preservatives, antioxidants, UV screening agents, bactericides, trace elements, odour absorbers and pH adjusters, and their mixtures
  • these various agents are those conventionally used in the field under consideration, for example from 0.01 to 20% of the total weight of the composition.
  • These adjuvants depending on their nature, can be introduced in the fatty phase or in the aqueous phase. In any case, these agents, and their proportions, will be chosen so as not to harm the properties desired for the microporous crystalline material comprising NO according to the invention.
  • emulsifiers and coemulsifiers which can be used, for example, of O/W emulsifiers, such as esters of fatty acid and of polyethylene glycol, in particular PEG-100 stearate, and esters of fatty acid and of glycerol, such as glyceryl stearate, as well as of W/O emulsifiers available, for example, under the trade names
  • colouring materials of monochrome pigments, pearlescent agents, reflecting pigments which do or do not emit a colour, interferential pigments, fat-soluble dyes, water-soluble dyes, and their mixtures.
  • the fat-soluble dyes are, for example, Sudan Red, DC Red 17, DC Green 6, ⁇ -carotene, soybean oil, Sudan Brown, DC Yellow 11, DC Violet 2, DC Orange 5 or quinoline yellow.
  • the pigments can be white or coloured, inorganic and/or organic and coated or uncoated. Mention may be made, among inorganic pigments, of titanium dioxide, optionally surface treated, zirconium or cerium oxides, iron or chromium oxides, manganese violet, ultramarine blue, chromium hydrate and ferric blue. Mention may be made, among organic pigments, of carbon black, pigments of D&C type and lakes, based on cochineal carmine, of barium, strontium, calcium or aluminium.
  • the pearlescent pigments can be chosen from white pearlescent pigments, such as mica covered with titanium oxide or bismuth oxychloride, coloured pearlescent pigments, such as titanium oxide-coated mica with iron oxides, titanium oxide-coated mica with in particular ferric blue or chromium oxide, or titanium oxide-coated mica with an organic pigment of the abovementioned type, and pearlescent pigments based on bismuth oxychloride.
  • the pigments may have been subjected to a surface treatment.
  • hydrophilic or lipophilic active agents suitable for use in the compositions of the invention of cosmetic active agents intended to improve the aesthetic appearance of the skin and/or lips.
  • composition according to the invention can additionally comprise at least one agent chosen from: agents which act on the microcirculation, desquamating and moisturizing agents, depigmenting or propigmenting agents, antiglycation agents, - agents which stimulate the synthesis of dermal or epidermal macromolecules and/or which prevent their decomposition, agents which stimulate the proliferation of fibroblasts or keratinocytes and/or the differentiation of keratinocytes, muscle relaxants or dermo-decontracting agents, tightening agents, agents for combating pollution or free radicals, soothing agents.
  • agents which act on the microcirculation desquamating and moisturizing agents, depigmenting or propigmenting agents, antiglycation agents, - agents which stimulate the synthesis of dermal or epidermal macromolecules and/or which prevent their decomposition, agents which stimulate the proliferation of fibroblasts or keratinocytes and/or the differentiation of keratinocytes, muscle relaxants or dermo-decontracting agents, tightening agents
  • the active agents which act on the microcirculation can be chosen from flavonoids, ruscogenins, esculosides, the aescin extracted from horse chestnut, nicotinates, hesperidin methyl chalcone, essential oils of lavender or rosemary, or Ammi visnaga extracts.
  • nicotinic acid and its derivatives such as nicotinic acid esters,
  • treating agent is understood to mean any compound capable of acting:
  • ⁇ -hydroxy acids in particular salicylic acid and its derivatives (including 5- (n-octanoyl) salicylic acid); ⁇ -hydroxy acids, such as glycolic acid, citric acid, lactic acid, tartaric acid, malic acid or mandelic acid; urea; gentisic acid; oligofucoses; cinnamic acid; Saphora jap ⁇ nica extract; resveratrol and some jasmonic acid derivatives;
  • corneodesmosomes or on the enzymes involved in desquamation or decomposition of the corneodesmosomes, such as glycosidases, stratum corneum chymotryptic enzyme (SCCE) or indeed even other proteases (trypsin, chymotrypsin-like) .
  • SCCE stratum corneum chymotryptic enzyme
  • agents which chelate inorganic salts include EDTA; N-acyl-N, N' , N' -ethylene- diaminetriacetic acid; aminosulphonic compounds and in particular N- (2-hydroxyethyl) piperazine-N' -2-ethane- sulphonic acid (HEPES) ; 2-oxothiazolidine-4-carboxylic acid (procysteine) derivatives; derivatives of ⁇ -amino acids of glycine type (as disclosed in EP-O 852 949, and also the sodium methylglycinediacetate sold by BASF under the trade name Trilon M) ; honey; or sugar derivatives, such as O-octanoyl-6-D-maltose and N-acetylglucosamine .
  • moistureturizing agent is understood to mean: - either a compound which acts on the barrier function, for the purpose of keeping the stratum corneum moisturized, or an occlusive compound. Mention may be made of ceramides, sphingoid-based compounds, lecithins, glycosphingolipids, phospholipids, cholesterol and its derivatives, phytosterols (stigmasterol, ⁇ -sitosterol or campesterol) , essential fatty acids, 1, 2-diacylglycerol, 4-chromanone, pentacyclic triterpenes, such as ursolic acid, petroleum jelly and lanolin;
  • a compound which directly increases the water content of the stratum corneum such as threalose and its derivatives, hyaluronic acid and its derivatives, glycerol, pentanediol, sodium pidolate, serine, xylitol, sodium lactate, glyceryl polyacrylate, ectoin and its derivatives, chitosan, oligo- and polysaccharides, cyclic carbonates,
  • steroid derivatives including DHEA or its 7-oxidized and/or 17-alkylated derivatives, and sapogenins
  • methyl dihydrojasmonate and vitamin D and its derivatives.
  • depigmenting or propigmenting agents capable of being incorporated in the composition according to the present invention comprise, for example, the following compounds: kojic acid; ellagic acid; arbutin and its derivatives, such as those disclosed in Applications EP-895 779 and EP-524 109; hydroquinone; aminophenol derivatives, such as those disclosed in Applications WO 99/10318 and WO 99/32077, in particular N-cholesteryloxycarbonyl-para-aminophenol and N-ethyloxycarbonyl-para-aminophenol; iminophenol derivatives, in particular those disclosed in Application WO 99/22707; L-2-oxothiazolidine-4- carboxylic acid or procysteine, and its salts and esters; calcium D-pantetheinesulphonate; ascorbic acid and its derivatives, in particular ascorbyl glucoside; and plant extracts
  • antiglycation agent is understood to mean a compound which prevents and/or reduces the glycation of skin proteins, in particular of dermal proteins, such as collagen.
  • antiglycation agents are plant extracts of the Ericaceae family, such as an extract of blueberry ⁇ Vaccinium angustifolium) ; ergothioneine and its derivatives; and hydroxystilbenes and their derivatives, such as resveratrol and 3, 3', 5,5'- tetrahydroxystilbene .
  • These antiglycation agents are disclosed in Applications FR 2 802 425, FR 2 810 548, FR 2 796 278 and FR 2 802 420, respectively.
  • Resveratrol is particularly preferred for use in this invention.
  • fibronectin such as the extract of Salina zooplankton sold by Seporga under the trade name GP4G ® ; the yeast extract available in particular from Alban M ⁇ ller under the trade name Drieline ® ; and the palmitoyl pentapeptide sold by Sederma under the trade name Matrixil ® ; - or on the inhibition of metalloproteinases (MMP) , such as more particularly MMP 1, 2, 3 or 9.
  • MMP metalloproteinases
  • serine proteases such as leukocyte elastase or cathepsin G.
  • active agents which stimulate epidermal macromolecules such as filaggrin and keratins
  • the agents which stimulate the proliferation of fibroblasts which can be used in the composition according to the invention can, for example, be chosen from plant proteins or polypeptides, extracts, in particular of soybean (for example, a soybean extract sold by LSN under the name Eleseryl SH-VEG 8 ® or sold by Silab under the trade name Raffermine ® ) ; and plant hormones, such as gibberellins and cytokinins.
  • the agents which stimulate the proliferation of keratinocytes which can be used in the composition according to the invention comprise in particular retinoids, such as retinol and its esters, including retinyl palmitate; adenosine; phloroglucinol; the extracts of walnut meal sold by Gattefosse; and the extracts of Solanum tuberosum sold by Sederma.
  • retinoids such as retinol and its esters, including retinyl palmitate; adenosine; phloroglucinol; the extracts of walnut meal sold by Gattefosse; and the extracts of Solanum tuberosum sold by Sederma.
  • the agents which stimulate the differentiation of keratinocytes comprise, for example, inorganic materials, such as calcium; a peptide extract of lupin, such as that sold by Silab under the trade name Structurine ® ; sodium ⁇ -sitosteryl sulphate, such as that sold by Seporga under the trade name Phytocohesine ® ; and a water-soluble extract of maize, such as that sold by Solabia under the trade name
  • the muscle relaxants or dermo-decontracting agents which can be used in the composition according to the invention comprise alverine and its salts, manganese gluconate, diazepam, the hexapeptide Argireline R sold by Lipotec, some carbonylated secondary and tertiary amines, adenosine, and also sapogenins and the natural extracts, in particular of wild yam, comprising them, and also Boswellia serrata extracts. Tightening agents
  • tensioning agent is understood to mean a compound capable of exerting tension on the skin, the effect of which is to temporarily render less dinstinct unevennesses in the surface of the skin, such as wrinkles and fine lines.
  • synthetic polymers such as polyurethane latices or acrylic-silicone latices, in particular those disclosed in Patent Application EP-I 038 519, such as a polydimethylsiloxane grafted with propylthio [poly (methyl acrylate) ] , propylthio [poly-
  • grafted silicone polymers are sold in particular by 3M under the trade names VS 80, VS 70 or L021,
  • polymers of natural origin in particular (a) polysaccharides, for example (i) in the form of starch resulting in particular from rice, maize, potato, manioc, peas, wheat, oats, and the like, or (ii) in the form of carrageenans, alginates, agars, gellans, cellulose polymers and pectins, advantageously as an aqueous dispersion of gel microparticles, and (b) latices composed of shellac resin, gum sandarac, dammars, elemis, copals, cellulose derivatives, and their mixtures, (3) plant proteins and protein hydrolysates, in particular of maize, rye, wheat, buckwheat, sesame, spelt, peas, broad beans, lentils, soybeans and lupin,
  • wax microparticles for example chosen from carnauba, candelilla or lucerne waxes
  • colloidal particles of inorganic filler having a number-average diameter of between 0.1 and 100 nm, preferably between 3 and 30 nm, and chosen, for example, from: silica, silica/alumina composites, cerium oxide, zirconium oxide, alumina, calcium carbonate, barium sulphate, calcium sulphate, zinc oxide and titanium dioxide.
  • Agents for combating pollution or free radicals are chosen, for example, from: silica, silica/alumina composites, cerium oxide, zirconium oxide, alumina, calcium carbonate, barium sulphate, calcium sulphate, zinc oxide and titanium dioxide.
  • agent for combating pollution is understood to mean any compound capable of trapping ozone, mono- or polycyclic aromatic compounds, such as benzopyrene, and/or heavy metals, such as cobalt, mercury, cadmium and/or nickel.
  • agent for combating free radicals is understood to mean any compound capable of trapping free radicals.
  • ozone- trapping agents which can be used in the composition according to the invention, of vitamin C and its derivatives, including ascorbyl glucoside; phenols and polyphenols, in particular tannins, ellagic acid and tannic acid; epigallocatechin and the natural extracts comprising it; extracts of olive tree leaf; extracts of tea, in particular of green tea; anthocyans; extracts of rosemary; phenol acids, in particular chlorogenic acid; stilbenes, in particular resveratrol; sulphur- comprising amino acid derivatives, in particular S-carboxymethylcysteine; ergothioneine; N-acetyl- cysteine; chelating agents, such as N, N' -bis (3, 4, 5- trimethoxybenzyl) ethylenediamine or one of its salts, metal complexes or esters; carotenoids, such as crocetin; and various starting materials, such as the mixture of arginine, hist
  • tannins such as ellagic acid
  • indole derivatives in particular indole-3-carbinol
  • extracts of tea in particular of green tea
  • extracts of water hyacinth or Eichhornia crassipes extracts of water hyacinth or Eichhornia crassipes
  • the water-soluble fraction of maize sold by Solabia under the trade name Phytovityl ® .
  • agents which trap heavy metals which can be used in the composition according to the invention, of chelating agents, such as EDTA, the pentasodium salt of ethylenediaminetetramethylenephosphonic acid, and N, N' -bis (3, 4, 5-trimethoxybenzyl) ethylenediamine or one of its salts, metal complexes or esters; phytic acid; chitosan derivatives; extracts of tea; in particular of green tea; tannins, such as ellagic acid; sulphur- comprising amino acids, such as cysteine; extracts of water hyacinth ⁇ Eichhornia crassipes) ; and the water- soluble fraction of maize sold by Solabia under the trade name Phytovityl ® .
  • chelating agents such as EDTA, the pentasodium salt of ethylenediaminetetramethylenephosphonic acid, and N, N' -bis (3, 4, 5-trimethoxybenzyl) ethylened
  • the agents for combating free radicals which can be used in the composition according to the invention comprise, in addition to some agents for combating pollution mentioned above, vitamin E and its derivatives, such as tocopheryl acetate; bioflavonoids; coenzyme QlO or ubiquinone; certain enzymes, such as catalase, superoxide dismutase and wheat germ extracts comprising it, lactoperoxidase, glutathione peroxidase and quinone reductases; glutathione; benzylidene- camphor; benzylcyclanones; substituted naphthalenones; pidolates; phytanthriol; ⁇ -oryzanol; guanosine; lignans; and melatonin.
  • vitamin E and its derivatives such as tocopheryl acetate; bioflavonoids; coenzyme QlO or ubiquinone
  • certain enzymes such as catalase, superoxide dismutase and wheat
  • Soothing agents Mention may be made, as soothing agents which can be used in the composition according to the invention, of: pentacylic triterpenes and plant extracts (for example, Glycyrrhiza glabra) comprising them, such as ⁇ -glycyrrhetinic acid and its salts and/or its derivatives (glycyrrhetinic acid monoglucuronide, stearyl glycyrrhetinate or 3-stearoyl- oxyglycyrrhetic acid) , ursolic acid and its salts, oleanolic acid and its salts, betulinic acid and its salts, extracts of plants, such as Paeonia suffrutlcosa and/or lactiflora, Laminaria saccharina , Boswellia serrata, Centipeda cunninghamii , Helianthus annuus, Linum usitatiss ⁇ mum, Cola nitida, Epi
  • the composition can be provided in any dosage form normally used in the cosmetics field which is suitable for the oral or topical route, preferably for the topical route on the skin.
  • oral cosmetics it can be provided in particular in the form of capsules, including hard gelatin capsules, tablets, including sugar-coated tablets, granules, chewing gum, gels, syrups to be taken orally or any other form known to a person skilled in the art.
  • the active agent (s) according to the invention can be incorporated in any form of food supplement or enriched foods, for example food bars, or compacted or noncompacted powders.
  • the powders can be dilutable in water, fizzy drinks, dairy products or soy derivatives or can be incorporated in food bars.
  • the active agents can be formulated with excipients and components conventional for such oral compositions or food supplements, namely, in particular, fatty and/or aqueous components, humectant agents, thickeners, preservatives, texturizing, flavouring and/or coating agents, antioxidants and colorants conventional in the food field.
  • the formulating agents and excipients for oral compositions and in particular for food supplements are known in this field and do not form here the subject of a detailed description.
  • An oral composition can in particular be advantageous for the "good look effect" on the complexion application.
  • the composition can in particular have the form of an aqueous, aqueous/alcoholic or oily solution which is optionally gelled, of an emulsion with a liquid or semiliquid consistency of the milk type, obtained by dispersing a fatty phase in an aqueous phase (O/W) or vice versa (W/0) , of a triple emulsion (W/O/W or
  • a suspension or emulsion with a soft, semisolid or solid consistency of cream or gel type of a liquid, pasty or solid anhydrous product, of micro- emulsions, of microcapsules, of microparticles, of a vesicular dispersion of ionic type (liposomes or oleosomes) and/or nonionic type (niosomes) and/or of a dispersion of nanospheres.
  • compositions in the foam form or in the spray or aerosol form then comprising a pressurized propellant.
  • the composition can thus be provided in the form of a lotion, serum, milk, 0/W or W/0 cream, gel, ointment, salve, powder, balm, patch, impregnated pad, soap, bar or foam.
  • the proportion of the fatty phase of the composition under consideration can range, for example, from 5 to 80% by weight, in particular from 5 to 50% by weight, with respect to the total weight of the composition.
  • the zeolites comprising the NO are preferably incorporated in this fatty phase.
  • the aqueous phase can be composed of water or can comprise a mixture of water and of water-miscible organic solvent (miscibility in water of greater than 50% by weight at 25 0 C), such as lower monoalcohols having from 1 to 5 carbon atoms, such as ethanol or isopropanol, glycols having from 2 to 8 carbon atoms, such as propylene glycol, ethylene glycol, 1,3-butylene glycol or dipropylene glycol, C 3 -C 4 ketones and C 2 -C 4 aldehydes .
  • water-miscible organic solvent miscibility in water of greater than 50% by weight at 25 0 C
  • lower monoalcohols having from 1 to 5 carbon atoms, such as ethanol or isopropanol
  • glycols having from 2 to 8 carbon atoms such as propylene glycol, ethylene glycol, 1,3-butylene glycol or dipropylene glycol, C 3 -C 4 ketones and C 2 -C
  • This aqueous phase (water and optionally the water-miscible organic solvent) can be present in the base composition in a content ranging from 1% to 95% by weight, in particular ranging from 3% to 80% by weight and especially ranging from 5% to 60% by weight, with respect to the total weight of the base composition.
  • the fatty phase of the composition can comprise fatty or oily compounds and optionally waxes, gums or pasty fatty substances of vegetable, animal, mineral or synthetic origin which may or may not comprise silicone.
  • oils for example, of: hydrocarbon oils of animal origin, such as perhydrosqualene; hydrocarbon oils of vegetable origin, such as liquid triglycerides of fatty acids comprising from 4 to 10 carbon atoms and the liquid fraction of shea butter; synthetic esters and ethers, in particular of fatty acids, such as oils of formulae R 1 COOR 2 and R 1 OR 2 in which R 1 represents the residue of a fatty acid comprising from 8 to 29 carbon atoms and R 2 represents a branched or unbranched hydrocarbon chain comprising from 3 to 30 carbon atoms, such as, for example, purcellin oil, isononyl isononanoate, isopropyl myristate, 2-ethylhexyl palmitate, 2-octyldodecyl stearate, 2-octyldodecyl erucate or isostearyl isostearate; hydroxylated esters, such as isostearyl lac
  • the waxes can be hydrocarbon waxes, silicone waxes and/or fluorinated waxes optionally comprising ester or hydroxyl functional groups . They are in particular of natural origin.
  • the wax can represent from 0.01 to 10% by weight, in particular form 0.1 to 5% by weight, with respect to the total weight of the composition.
  • wax which can be used in the composition of the invention, of beeswax, carnauba wax, candelilla wax, paraffin wax, microcrystalline waxes, ceresin or ozokerite, synthetic waxes, such as polyethylene or Fischer-Tropsch waxes, or silicone waxes, such as alkyl or alkoxy dimethicones having from 16 to 45 carbon atoms.
  • Use may also be made of esters of fatty acids or of fatty alcohols, in particular those having 20 to 65 carbon atoms, such as triisostearyl or cetyl citrate; arachidyl propionate; poly(vinyl laurate) ; or cholesterol esters, such as triglycerides of vegetable origin, such as hydrogenated vegetable oils, viscous polyesters and their mixtures.
  • Use may be made, as triglyceride of vegetable origin, of derivatives of hydrogenated castor oil, such as "Thixinr®" from Rheox.
  • polyesters resulting from the esterification of a carboxylic acid and of a hydroxycarboxylic acid ester of aliphatic nature for example Risocast® DA-L (ester resulting from the esterification reaction of hydrogenated castor oil with dilinoleic acid in proportions of 2 to 1) and Risocast® DA-H (ester resulting from the esterification of hydrogenated castor oil with isostearic acid in proportions of 4 to 3), sold by the Japanese company Kokyu Alcohol Kogyo.
  • PDMSs polydimethylsiloxanes
  • stearyl dimethicones in particular those sold by Dow Corning under the trade names DC2503® and DC25514®, and their mixtures.
  • the zeolites comprising NO are preferably incorporated in the anhydrous fatty matrix of the said composition.
  • the composition for caring for and/or making up the skin according to the invention can be provided in the form of a care base or cream for the skin, of a make-up base, of a tinted cream, of a foundation in the liquid or semisolid or powder form, of a care product for the contour of the eye, of a serum for caring for lines around the eyes or of a concealer stick.
  • composition for caring for and/or making up the lips can be provided in the form of a lipstick, of a liquid gloss, of a lipstick paste, of a pencil for the contour of the lips, of a lip balm or of a lip varnish, otherwise known as lip lacquer.
  • the invention also relates to a cosmetic composition
  • a cosmetic composition comprising, in a physiologically acceptable medium, at least one microporous crystalline material comprising releasable adsorbed NO and at least one cosmetic active agent chosen from other agents which act on the microcirculation, desquamating and moisturizing agents, depigmenting or propigmenting agents, antiglycation agents, agents which stimulate the synthesis of dermal or epidermal macromolecules and/or which prevent their decomposition, agents which stimulate the proliferation of fibroblasts or keratinocytes and/or the differentiation of keratinocytes, muscle relaxants or dermo-decontracting agents, tightening agents, agents for combating pollution or free radicals, or soothing agents. Examples of these active agents are described above in the description.
  • the said microporous crystalline material comprising NO will be a zeolite comprising NO, preferably a zeolite comprising NO of formula (I) or (II) in which Mi and M 2 are extraframework metal cations of elements chosen from Zn or Mn.
  • Use will preferably be made of a zeolite comprising NO prepared according to Example 2b described in Application WO 2005/003032, incorporated by reference, and use will advantageously be made of a zeolite in which the extraframework metal cations of elements are Zn or Mn, referred to as zeolite Zn-NO and zeolite Mn-NO. It can additionally be advantageous to add, to the compositions of the invention, other agents intended to improve the aesthetic appearance of the skin and/or lips or to reinforce the desired effect, namely the "colouring and/or volume of the lips” effect, the "good look” of the complexion effect or the "concealer” effect.
  • compositions for the lips may be made, for example, in the compositions for the lips, of a make-up agent with an optical effect of volume, such as, for example, goniochromatic pigments, reflecting particles and their mixtures .
  • an optical effect of volume such as, for example, goniochromatic pigments, reflecting particles and their mixtures .
  • compositions for the skin of the face intended to confer a good look effect for example, of a self-tanning agent (for example, DHA) and/or colorants, such as red or orange colorants of fluoran type, such as those disclosed in Patent Application FR 2 840 806, incorporated by reference.
  • a self-tanning agent for example, DHA
  • colorants such as red or orange colorants of fluoran type, such as those disclosed in Patent Application FR 2 840 806, incorporated by reference.
  • agents which conceal lines around the eyes such as soft focus fillers, fluorescent agents, optical brighteners and their mixtures.
  • composition will additionally comprise at least one cosmetic adjuvant chosen from fillers, colouring materials, thickeners, emulsifiers, hydrophilic or lipophilic gelling agents, surfactants, moisturizing agents, softening agents, sequestering agents, fragrances, neutralizing agents, preservatives, antioxidants, UV screening agents, bactericides, trace elements, odour absorbers and pH adjusters, and their mixtures .
  • cosmetic adjuvant chosen from fillers, colouring materials, thickeners, emulsifiers, hydrophilic or lipophilic gelling agents, surfactants, moisturizing agents, softening agents, sequestering agents, fragrances, neutralizing agents, preservatives, antioxidants, UV screening agents, bactericides, trace elements, odour absorbers and pH adjusters, and their mixtures .
  • composition will preferably be a composition for topical application to the skin and/or lips.
  • an aqueous, aqueous/alcoholic or oily solution which is optionally gelled, of an emulsion with a liquid or semiliquid consistency of the milk type, obtained by dispersing a fatty phase in an aqueous phase (O/W) or vice versa (W/0) , of a triple emulsion (W/O/W or 0/W/O) , of a suspension or emulsion with a soft, semisolid or solid consistency of cream or gel type, of a liquid, pasty or solid anhydrous product, of microemulsions, of microcapsules, of microparticles, of a vesicular dispersion of ionic type (liposomes or oleosomes) and/or nonionic type (niosomes) and/or of a dispersion of nanospheres.
  • compositions in the foam form or in the spray or aerosol form then comprising a pressurized propellant.
  • the composition can thus be a lotion, serum, milk, 0/W or W/0 cream, gel, ointment, salve, powder, balm, patch, impregnated pad, soap, bar or foam.
  • it can be a natural make-up product for the skin in the form of a care base or cream for the skin, of a make-up base, of a tinted cream, of a foundation in the liquid or semisolid or powder form, of a care product for the contour of the eye, of a serum for caring for lines around the eyes or of a concealer stick, a concealer gel, a concealer cream, or a natural make-up product for the lips in the form of a lipstick, of a liquid gloss, of a lipstick paste, of a pencil for the contour of the lips, of a lip balm or of a lip varnish, otherwise known as lip lacquer.
  • the invention also relates to a cosmetic process targeted at improving the appearance of the skin, contour of the eye and/or lips, characterized in that a composition as defined above is applied to the skin, contact of the eye and/or lips.
  • the process is targeted at giving a good look effect to the complexion or at reducing lines around the eyes and/or bags or at rendering the lips full and/or naturally coloured.
  • the compositions of the invention will be suitable for beautifying the appearance of the skin and/or lips of subjects 60
  • Example 1 Preparation of zeolites Zn-NO and Mn-NO
  • the zeolites Zn-NO and Mn-NO are prepared according to Example 2b of Application WO 2005/003032, incorporated by reference.
  • the sodium ions are subsequently replaced by transition metal cations known for binding nitrogen monoxide (for example: Mn 2+ or Zn 2+ ), in order to obtain ion-exchange zeolites, according to the following protocol: sodium zeolite A (5 g) is placed in a 0.05M metal acetate solution (400 ml, distilled water) and dried at 100 0 C overnight.
  • transition metal cations known for binding nitrogen monoxide for example: Mn 2+ or Zn 2+
  • the zeolites are analysed using the Agilent 7500 ICP-MS spectrometer.
  • the zeolites A respectively comprising Mn or Zn are subsequently dehydrated.
  • 0.3 g of the zeolite A Mn or Zn thus prepared is dehydrated at 300 0 C for 2 hours (0.5 mmHg) . It is subsequently cooled to ambient temperature and exposed to a nitrogen monoxide/helium (10% NO, 90% He) gas mixture at a pressure of 3 atmospheres for 10 minutes and then exposed again to nitrogen monoxide at a pressure of 3 atmospheres. This stage is repeated 3 times .
  • the ability of the NO to be released is subsequently measured in the presence of a stream of argon (either saturated with water vapour or taken directly from a gas cylinder, 5 ml.min "1 ) .
  • Example 2 Formulations Lipstick - Polyethylene wax (MW 500) 12.00%

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

L’invention concerne l’usage cosmétique dans une composition d’au moins un matériau microporeux solide cristallin comprenant du monoxyde d’azote adsorbé libérable comme agent visant à améliorer la couleur de la peau et/ou des lèvres et/ou l’apparence des lèvres.
PCT/EP2006/002660 2005-03-15 2006-03-03 Usage cosmetique d’un materiau microporeux solide cristallin (monoxyde d’azote) pour ameliorer la coloration et/ou l’apparence naturelle de la peau et/ou des levres WO2006097349A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0550658 2005-03-15
FR0550658A FR2883163B1 (fr) 2005-03-15 2005-03-15 Utilisation cosmetique d'un materiau solide cristallin microporeux contenant du no pour ameliorer l'aspect et/ou la coloration naturelle de la peau et/ou des levres
US66657005P 2005-03-31 2005-03-31
US60/666,570 2005-03-31

Publications (1)

Publication Number Publication Date
WO2006097349A1 true WO2006097349A1 (fr) 2006-09-21

Family

ID=36406577

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/002660 WO2006097349A1 (fr) 2005-03-15 2006-03-03 Usage cosmetique d’un materiau microporeux solide cristallin (monoxyde d’azote) pour ameliorer la coloration et/ou l’apparence naturelle de la peau et/ou des levres

Country Status (1)

Country Link
WO (1) WO2006097349A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012131412A2 (fr) 2011-03-31 2012-10-04 Szabo Laszlo Gabor Composition pharmaceutique contenant du no, procédé de préparation et utilisation de celui-ci
RU2677882C1 (ru) * 2018-02-27 2019-01-22 Наталья Витальевна Леснова Биологически активная цеолитсодержащая добавка, используемая в качестве компонента косметического средства для окрашивания волос и косметическое средство для окрашивания волос на ее основе
RU2696879C1 (ru) * 2018-11-12 2019-08-07 Наталья Витальевна Леснова Косметическая маска для ухода за кожей

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5184630A (en) * 1992-04-06 1993-02-09 Uop Hair deodorizing compositions and process for using
US6103275A (en) * 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
WO2003072039A2 (fr) * 2002-02-22 2003-09-04 Essentia Biosystems, Inc. Formulations cosmetiques contenant des oligomeres de l-arginine
WO2005003032A1 (fr) * 2003-07-03 2005-01-13 The University Court Of The University Of St Andrews Zeolites pour administrer de l'acide nitrique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5184630A (en) * 1992-04-06 1993-02-09 Uop Hair deodorizing compositions and process for using
US6103275A (en) * 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
WO2003072039A2 (fr) * 2002-02-22 2003-09-04 Essentia Biosystems, Inc. Formulations cosmetiques contenant des oligomeres de l-arginine
WO2005003032A1 (fr) * 2003-07-03 2005-01-13 The University Court Of The University Of St Andrews Zeolites pour administrer de l'acide nitrique

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012131412A2 (fr) 2011-03-31 2012-10-04 Szabo Laszlo Gabor Composition pharmaceutique contenant du no, procédé de préparation et utilisation de celui-ci
RU2677882C1 (ru) * 2018-02-27 2019-01-22 Наталья Витальевна Леснова Биологически активная цеолитсодержащая добавка, используемая в качестве компонента косметического средства для окрашивания волос и косметическое средство для окрашивания волос на ее основе
RU2696879C1 (ru) * 2018-11-12 2019-08-07 Наталья Витальевна Леснова Косметическая маска для ухода за кожей

Similar Documents

Publication Publication Date Title
US20030224028A1 (en) Metal complexes for promoting skin desquamation and/or stimulating epidermal renewal
US20020182238A1 (en) Fibers as anti-irritant agents
US20060272103A1 (en) Compositions comprising KAP polypeptides
FR2880802A1 (fr) Composition cosmetique ou dermopharmaceutique contenant un extrait d'euglene
JP6323972B2 (ja) 単糖とアスコルビン酸との組合せ及び化粧品におけるその使用
JPS61289016A (ja) 皮膚外用剤
JP2000212082A (ja) 皮膚用剤
JP6043145B2 (ja) 体臭抑制用の皮膚外用組成物
WO2006097348A1 (fr) Utilisation d’agents comme les donneurs d’oxyde nitrique non polymeriques pour rendre les levres a nouveau charnues et/ou colorer les levres
EP1795181A1 (fr) Utilisations cosmétiques et pharmaceutiques de l'association du dipeptide tyrosine-arginine et de la niacinamide en tant qu'antagoniste de substance P
FR2883170A1 (fr) Utilisation d'agents tels que des donneurs ou liberateurs non polymeriques de monoxyde d'azote pour colorer naturellement la peau
WO2006097349A1 (fr) Usage cosmetique d’un materiau microporeux solide cristallin (monoxyde d’azote) pour ameliorer la coloration et/ou l’apparence naturelle de la peau et/ou des levres
JP2003063925A (ja) 皮膚外用剤
JP2003335630A (ja) 落屑剤としての少なくとも１つの金属錯体の使用
WO2006101119A1 (fr) Promoteur de synthese du collagene
US11045471B2 (en) Melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promotor and wrinkle ameliorant
US20070059269A1 (en) Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer
WO2008090489A2 (fr) Utilisation de soins cosmétiques pour la peau à base de combinaisons de gluconate de fer
JP5198899B2 (ja) 細胞賦活剤及び老化防止用皮膚外用剤
JP2002275018A (ja) 皮膚外用剤
JP5226200B2 (ja) 硫酸化グリコサミノグリカン産生促進剤およびこれを含有する皮膚外用剤
JP2005290002A (ja) 少なくとも一のＲｈｏＡキナーゼの生成及び／又は活性化インヒビターの、皮膚を脱収縮させ及び／又は表情を弛緩させる薬剤としての美容的使用
EP1526833A1 (fr) Utilisation de lignanes pour prevenir ou traiter les signes de vieillissement de la peau
JP2009256269A (ja) プロフィラグリン及び／又はフィラグリン産生促進剤
JP5420848B2 (ja) 美白剤及び美白用皮膚外用剤

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

WWW Wipo information: withdrawn in national office

Country of ref document: RU

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 06723651

Country of ref document: EP

Kind code of ref document: A1

122 Ep: pct application non-entry in european phase

Ref document number: 06723651

Country of ref document: EP

Kind code of ref document: A1

WWW Wipo information: withdrawn in national office

Ref document number: 6723651

Country of ref document: EP