WO2006090268A3 - Processes for the preparation of alfuzosin and salts thereof and novel crystalline forms of alfuzosin - Google Patents

Processes for the preparation of alfuzosin and salts thereof and novel crystalline forms of alfuzosin Download PDF

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Publication number
WO2006090268A3
WO2006090268A3 PCT/IB2006/000431 IB2006000431W WO2006090268A3 WO 2006090268 A3 WO2006090268 A3 WO 2006090268A3 IB 2006000431 W IB2006000431 W IB 2006000431W WO 2006090268 A3 WO2006090268 A3 WO 2006090268A3
Authority
WO
WIPO (PCT)
Prior art keywords
alfuzosin
crystalline forms
processes
preparation
salts
Prior art date
Application number
PCT/IB2006/000431
Other languages
French (fr)
Other versions
WO2006090268A2 (en
Inventor
Narendra Shriram Joshi
Buddhavarapu Pattabhi Ramam
Kodali Eswara Rao
Shekhar Bhaskar Bhirud
Nitin S Pradhan
Original Assignee
Glenmark Pharmaceuticals Ltd
Narendra Shriram Joshi
Buddhavarapu Pattabhi Ramam
Kodali Eswara Rao
Shekhar Bhaskar Bhirud
Nitin S Pradhan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Ltd, Narendra Shriram Joshi, Buddhavarapu Pattabhi Ramam, Kodali Eswara Rao, Shekhar Bhaskar Bhirud, Nitin S Pradhan filed Critical Glenmark Pharmaceuticals Ltd
Publication of WO2006090268A2 publication Critical patent/WO2006090268A2/en
Publication of WO2006090268A3 publication Critical patent/WO2006090268A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides novel crystalline forms of a.lfuzosin and alfuzosin hydrochloride and processes for their preparation. Also provided are pharmaceutical compositions containing the new crystalline forms.
PCT/IB2006/000431 2005-02-28 2006-02-28 Processes for the preparation of alfuzosin and salts thereof and novel crystalline forms of alfuzosin WO2006090268A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
IN215MU2005 2005-02-28
IN215/MUM/2005 2005-02-28
US66250505P 2005-03-16 2005-03-16
US60/662,505 2005-03-16
IN711/MUM/2005 2005-06-17
IN711MU2005 2005-06-17
US69674305P 2005-07-06 2005-07-06
US60/696,743 2005-07-06

Publications (2)

Publication Number Publication Date
WO2006090268A2 WO2006090268A2 (en) 2006-08-31
WO2006090268A3 true WO2006090268A3 (en) 2006-10-26

Family

ID=36568690

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/000431 WO2006090268A2 (en) 2005-02-28 2006-02-28 Processes for the preparation of alfuzosin and salts thereof and novel crystalline forms of alfuzosin

Country Status (1)

Country Link
WO (1) WO2006090268A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070105880A1 (en) * 2005-11-08 2007-05-10 Torrent Pharmaceuticals Limited Process for the preparation of alfuzosin
US20090069562A1 (en) * 2005-12-26 2009-03-12 Joseph Prabahar Koilpillai Process for the preparation of alfuzosin
WO2007063556A2 (en) * 2006-12-07 2007-06-07 Msn Laboratories Limited An improved and industrial process for the preparation of alfuzosin hydrochloride and its novel polymorphs
WO2008114272A2 (en) * 2007-03-22 2008-09-25 Cadila Healthcare Limited Process for preparing alpuzosin and crystalline alfuzosin hydrochloride
EP2152697A2 (en) 2007-05-04 2010-02-17 Actavis Group PTC EHF Process for the preparation of alfuzosin and salts thereof
WO2009001369A1 (en) * 2007-06-22 2008-12-31 Alembic Limited An improved process for the preparation of alfuzosin hydrochloride
WO2009007987A1 (en) * 2007-07-11 2009-01-15 Alembic Limited An improved process for the preparation of alfuzosin and its novel polymorph
AU2008281567B2 (en) 2007-08-02 2012-07-26 Cipla Limited Process for the preparation of alfuzosin hydrochloride
CN108069945A (en) * 2017-12-31 2018-05-25 威海贯标信息科技有限公司 A kind of Alfuzosin novel crystal forms
CN113801069B (en) * 2020-06-15 2024-03-15 鲁南制药集团股份有限公司 Alfuzosin hydrochloride intermediate compound
CN114573569B (en) * 2022-03-30 2023-07-04 邦恩泰(山东)生物医药科技集团股份有限公司 Preparation method of isoquinoline compound

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5315007A (en) * 1990-12-20 1994-05-24 North Carolina State University Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs
WO2006030449A1 (en) * 2004-09-16 2006-03-23 Hetero Drugs Limited Crystalline alfuzosin base

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5315007A (en) * 1990-12-20 1994-05-24 North Carolina State University Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs
WO2006030449A1 (en) * 2004-09-16 2006-03-23 Hetero Drugs Limited Crystalline alfuzosin base

Also Published As

Publication number Publication date
WO2006090268A2 (en) 2006-08-31

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