WO2006084276A2 - Synthese de nanoparticules metalliques catalysee par uneenzyme - Google Patents

Synthese de nanoparticules metalliques catalysee par uneenzyme Download PDF

Info

Publication number
WO2006084276A2
WO2006084276A2 PCT/US2006/004307 US2006004307W WO2006084276A2 WO 2006084276 A2 WO2006084276 A2 WO 2006084276A2 US 2006004307 W US2006004307 W US 2006004307W WO 2006084276 A2 WO2006084276 A2 WO 2006084276A2
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
nadph
nanoparticle
gold
fad
Prior art date
Application number
PCT/US2006/004307
Other languages
English (en)
Other versions
WO2006084276A3 (fr
Inventor
Daniel M. Scott
Michael D. Toney
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2006084276A2 publication Critical patent/WO2006084276A2/fr
Publication of WO2006084276A3 publication Critical patent/WO2006084276A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P3/00—Preparation of elements or inorganic compounds except carbon dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0423—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F9/00—Making metallic powder or suspensions thereof
    • B22F9/16—Making metallic powder or suspensions thereof using chemical processes
    • B22F9/18—Making metallic powder or suspensions thereof using chemical processes with reduction of metal compounds
    • B22F9/24—Making metallic powder or suspensions thereof using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F2998/00—Supplementary information concerning processes or compositions relating to powder metallurgy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Composite Materials (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne l'enzyme glutathione réductase FAD-dépendante qui permet de catalyser la synthèse NADPH-dépendente de nanoparticules d'or, de platine et de métaux mélangés qui sont fortement liées à un site via les résidus cystéine actifs de redox. Ladite enzyme permet de stabiliser de très petites grappes métalliques (?#126, 5 atomes) et empêche l'agrégation de grappes plus importantes en l'absence de ligands de protection. La juxtaposition des nanoparticules avec le cofacteur FAD via les cystéines de site actif permet de maintenir les nanoparticules à un bas potentiel en présence d'un excès de NADPH, ce qui permet de déposer des métaux en couche indépendamment du potentiel redox et de stabiliser des métaux à bas potentiel destinés à être oxydés dans une solution aqueuse. La synthèse des nanoparticules d'or catalysée par la glutathione réductase en phase solide est démontrée et proposée comme moyen de production à grande échelle d'une variété de structures de nanoparticules uniques.
PCT/US2006/004307 2005-02-04 2006-02-03 Synthese de nanoparticules metalliques catalysee par uneenzyme WO2006084276A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64998805P 2005-02-04 2005-02-04
US60/649,988 2005-02-04

Publications (2)

Publication Number Publication Date
WO2006084276A2 true WO2006084276A2 (fr) 2006-08-10
WO2006084276A3 WO2006084276A3 (fr) 2007-03-01

Family

ID=36778037

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/004307 WO2006084276A2 (fr) 2005-02-04 2006-02-03 Synthese de nanoparticules metalliques catalysee par uneenzyme

Country Status (1)

Country Link
WO (1) WO2006084276A2 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007146162A2 (fr) * 2006-06-08 2007-12-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Dispositifs, systèmes et procédés de réduction de la concentration d'une entité chimique dans des fluides
EP2315837A1 (fr) * 2008-08-21 2011-05-04 National Research Council of Canada Production de nanoparticules exemptes de soufre par une levure
CN101349667B (zh) * 2007-07-16 2011-11-23 中国科学院化学研究所 一种生理活性物质的电化学检测装置及其专用电化学传感器和制备方法
CN108642035A (zh) * 2018-05-08 2018-10-12 江苏理工学院 一种硅胶固定gdh催化制备nadph的方法
US10322221B2 (en) 2013-01-18 2019-06-18 University of Pittsburgh—of the Commonwealth System of Higher Education Removal of carbon dioxide via dialysis
WO2020036831A3 (fr) * 2018-08-10 2020-05-28 Colorado State University Research Foundation Marqueur enzymatique réducteur de métaux pour microscopie optique et électronique
CN111205852A (zh) * 2020-01-16 2020-05-29 吉林大学 一种谷胱甘肽保护的强荧光发射的金铂合金纳米簇及其可控制备方法
US10801052B2 (en) 2011-10-03 2020-10-13 Oxford University Innovation Limited Cofactor regeneration system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6962823B2 (en) * 2002-04-02 2005-11-08 Nanosys, Inc. Methods of making, positioning and orienting nanostructures, nanostructure arrays and nanostructure devices

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6962823B2 (en) * 2002-04-02 2005-11-08 Nanosys, Inc. Methods of making, positioning and orienting nanostructures, nanostructure arrays and nanostructure devices

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
KASHEFI K. ET AL.: 'Reductive precipitation of gold by dissimilarity Fe(III)-reducing bacteria and archaea' APPL. ENVIRON. MICROBIOL. vol. 67, no. 7, July 2001, pages 3275 - 3279, XP003002491 *
MUKHERJEE P. ET AL.: 'Bioreduction of AuCl(4)(-) ions by the fungus, Verticillium sp. and surface trapping of the gold nanoparticles formed' ANGEW. CHEM. INT. ED. ENGL. vol. 40, no. 19, 2001, pages 3585 - 3588, XP003002488 *
MUKHERJEE P. ET AL.: 'Extracellular of gold nanoparticles by the fungus Fusarium oxysporum' CHEMBIOCHEM. vol. 3, no. 5, 2002, pages 461 - 463, XP002354410 *
RAFTER G.W.: 'Copper inhibition of glutathione reductase and its reversal with gold thiolates, thiol, and disulfide compounds' BIOCHEM. MED. vol. 27, no. 3, 1982, pages 381 - 391, XP003002487 *
SCHUELER D.: 'Formation of magnetosomes in magnetotactic bacteria' J. MOL. MICROBIOL. BIOTECHNOL. vol. 1, no. 1, 1999, pages 79 - 86, XP003002490 *
SHANKAR S.S. ET AL.: 'Geranium leaf assisted biosynthesis of silver nanoparticles' BIOTECHNOL. PROG. vol. 19, no. 6, 2003, pages 1627 - 1631, XP001203465 *
SHANKAR S.S. ET AL.: 'Rapid synthesis of Au, Ag, and bimetallic Au core-Ag shell nanoparticles using Neem (Azadirachta indica) leaf broth' J. COLLOID INTERFACE SCI. vol. 275, no. 2, 2004, pages 496 - 502, XP003002489 *

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8323379B2 (en) 2006-06-08 2012-12-04 University of Pittsburgh—of the Commonwealth System of Higher Education Devices, systems and methods for reducing the concentration of a chemical entity in fluids
WO2007146162A3 (fr) * 2006-06-08 2008-03-13 Univ Pittsburgh Dispositifs, systèmes et procédés de réduction de la concentration d'une entité chimique dans des fluides
US7763097B2 (en) 2006-06-08 2010-07-27 University of Pittsburgh—of the Commonwealth System of Higher Education Devices, systems and methods for reducing the concentration of a chemical entity in fluids
WO2007146162A2 (fr) * 2006-06-08 2007-12-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Dispositifs, systèmes et procédés de réduction de la concentration d'une entité chimique dans des fluides
US8043411B2 (en) 2006-06-08 2011-10-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Devices, systems and methods for reducing the concentration of a chemical entity in fluids
CN101349667B (zh) * 2007-07-16 2011-11-23 中国科学院化学研究所 一种生理活性物质的电化学检测装置及其专用电化学传感器和制备方法
US8986975B2 (en) 2008-08-21 2015-03-24 National Research Council Of Canada Production of sulfur-free nanoparticles by yeast
EP2315837A4 (fr) * 2008-08-21 2012-07-04 Ca Nat Research Council Production de nanoparticules exemptes de soufre par une levure
EP2315837A1 (fr) * 2008-08-21 2011-05-04 National Research Council of Canada Production de nanoparticules exemptes de soufre par une levure
US10801052B2 (en) 2011-10-03 2020-10-13 Oxford University Innovation Limited Cofactor regeneration system
US10975408B2 (en) 2011-10-03 2021-04-13 Oxford University Innovation Limited Cofactor regeneration system
US10322221B2 (en) 2013-01-18 2019-06-18 University of Pittsburgh—of the Commonwealth System of Higher Education Removal of carbon dioxide via dialysis
CN108642035A (zh) * 2018-05-08 2018-10-12 江苏理工学院 一种硅胶固定gdh催化制备nadph的方法
WO2020036831A3 (fr) * 2018-08-10 2020-05-28 Colorado State University Research Foundation Marqueur enzymatique réducteur de métaux pour microscopie optique et électronique
CN111205852A (zh) * 2020-01-16 2020-05-29 吉林大学 一种谷胱甘肽保护的强荧光发射的金铂合金纳米簇及其可控制备方法
CN111205852B (zh) * 2020-01-16 2021-07-09 吉林大学 一种谷胱甘肽保护的强荧光发射的金铂合金纳米簇及其可控制备方法

Also Published As

Publication number Publication date
WO2006084276A3 (fr) 2007-03-01

Similar Documents

Publication Publication Date Title
WO2006084276A2 (fr) Synthese de nanoparticules metalliques catalysee par uneenzyme
Guo et al. Direct electrochemistry of proteins and enzymes
US7459223B2 (en) Electrochemical methods for generation of a biological proton motive force
US6495023B1 (en) Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration
Zhang et al. Third-generation biosensors based on the direct electron transfer of proteins
Cracknell et al. Enzymes as working or inspirational electrocatalysts for fuel cells and electrolysis
Zhao et al. Direct electron transfer at horseradish peroxidase—colloidal gold modified electrodes
Baron et al. Electrochemical measurement of electron transfer kinetics by Shewanella oneidensis MR-1
Heller Plugging metal connectors into enzymes
Immanuel et al. Recent progress and perspectives on electrochemical regeneration of reduced nicotinamide adenine dinucleotide (NADH)
Yang et al. A method for determination of glucose by an amperometric bienzyme biosensor based on silver nanocubes modified Au electrode
Barin et al. Direct electrochemical regeneration of 1, 4-NADH at the copper foam and bimetallic copper foam
Song et al. Conformation, bioactivity and electrochemical performance of glucose oxidase immobilized on surface of gold nanoparticles
Hickey et al. Fundamentals and applications of bioelectrocatalysis
Schlesinger et al. Electron transfer rate analysis of a site-specifically wired copper oxidase
Ratautas et al. Wiring Gold Nanoparticles and Redox Enzymes: A Self‐Sufficient Nanocatalyst for the Direct Oxidation of Carbohydrates with Molecular Oxygen
Zafar et al. An efficient and versatile membraneless bioanode for biofuel cells based on Corynascus thermophilus cellobiose dehydrogenase
Malel et al. Direct electron transfer between glucose oxidase and gold nanoparticles; when size matters
Zhang et al. Oxygen reduction catalyzed by bilirubin oxidase and applications in biosensors and biofuel cells
Adachi et al. Experimental and theoretical insights into bienzymatic cascade for mediatorless bioelectrochemical ethanol oxidation with alcohol and aldehyde dehydrogenases
Bogdanovskaya et al. Bioelectrocatalytic oxygen reduction by laccase immobilized on various carbon carriers
JP6484741B1 (ja) 新規メディエータ
Matsumoto et al. Two‐Stage Oxidation of Glucose by an Enzymatic Bioanode
Treu et al. Bioelectrocatalysis of pyruvate with PQQ-dependent pyruvate dehydrogenase
Nedoluzhko et al. Enzymatic oxidation of cadmium and lead metals photodeposited on cadmium sulfide

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 06734513

Country of ref document: EP

Kind code of ref document: A2