WO2006080630A8 - Pharmaceutical combination preparation for oral delivery for the treatment of diabetes mellitus - Google Patents

Pharmaceutical combination preparation for oral delivery for the treatment of diabetes mellitus

Info

Publication number
WO2006080630A8
WO2006080630A8 PCT/KR2005/003134 KR2005003134W WO2006080630A8 WO 2006080630 A8 WO2006080630 A8 WO 2006080630A8 KR 2005003134 W KR2005003134 W KR 2005003134W WO 2006080630 A8 WO2006080630 A8 WO 2006080630A8
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
diabetes mellitus
oral delivery
pharmaceutical combination
combination preparation
Prior art date
Application number
PCT/KR2005/003134
Other languages
French (fr)
Other versions
WO2006080630A1 (en
Inventor
Kwon Yeon Weon
Dong Wook Kim
Tae Han Kim
Jung Hoon Kim
Eun Jung Kim
Original Assignee
Handok Pharmaceuticals Co Ltd
Kwon Yeon Weon
Dong Wook Kim
Tae Han Kim
Jung Hoon Kim
Eun Jung Kim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Handok Pharmaceuticals Co Ltd, Kwon Yeon Weon, Dong Wook Kim, Tae Han Kim, Jung Hoon Kim, Eun Jung Kim filed Critical Handok Pharmaceuticals Co Ltd
Publication of WO2006080630A1 publication Critical patent/WO2006080630A1/en
Publication of WO2006080630A8 publication Critical patent/WO2006080630A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed are a combined pharmaceutical preparation for oral delivery for treatment of diabetes mellitus, comprising a) an inner layer comprising metformin or a pharmaceutically acceptable salt thereof, a swellable polymer and a pharmaceutically acceptable excipient, b) a drug-free intermediate layer comprising a water-soluble polymer, and c) an outer layer comprising glimepiride and a releasing controller; and a method for preparing the same.
PCT/KR2005/003134 2004-09-23 2005-09-22 Pharmaceutical combination preparation for oral delivery for the treatment of diabetes mellitus WO2006080630A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20040076535 2004-09-23
KR10-2004-0076535 2004-09-23

Publications (2)

Publication Number Publication Date
WO2006080630A1 WO2006080630A1 (en) 2006-08-03
WO2006080630A8 true WO2006080630A8 (en) 2006-12-14

Family

ID=36740629

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2005/003134 WO2006080630A1 (en) 2004-09-23 2005-09-22 Pharmaceutical combination preparation for oral delivery for the treatment of diabetes mellitus

Country Status (2)

Country Link
KR (1) KR100705210B1 (en)
WO (1) WO2006080630A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100831771B1 (en) * 2005-10-27 2008-05-27 주식회사종근당 Pharmaceutical composition having pH-dependant immediate release and extended release
KR100812538B1 (en) * 2006-10-23 2008-03-11 한올제약주식회사 Controlled release complex formulation comprising metformin and glimepiride
WO2008121702A2 (en) * 2007-03-28 2008-10-09 Boston Scientific Scimed, Inc. Medical devices having bioerodable layers for the release of therapeutic agents
KR101512386B1 (en) * 2008-04-08 2015-04-17 제이더블유중외제약 주식회사 Complex formulation comprising metformin and mitiglinide and method for preparation thereof
KR101189639B1 (en) * 2008-12-15 2012-10-12 씨제이제일제당 (주) Oral formulations comprising metformin and &-glycosidase inhibitor and processes for the preparation thereof
KR101597004B1 (en) 2013-07-25 2016-02-23 씨제이헬스케어 주식회사 Pharmaceutical combination comprising sustained-release type metformin and immediate-release type HMG-CoA reductase inhibitor
EA038558B1 (en) * 2013-10-14 2021-09-14 Зим Лэбораториз Лимитед Water soluble pharmaceutical film with enhanced stability
KR101526825B1 (en) * 2014-12-23 2015-06-08 주식회사 한독 Pharmaceutical Compositions for The Treatment of Diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0213079A (en) * 2001-09-28 2004-11-09 Sun Pharmaceutical Ind Ltd Dosage form for the treatment of diabetes mellitus
KR100568951B1 (en) * 2002-12-26 2006-04-07 스미도모쥬기가이고교 가부시키가이샤 Reducer for transfer crane
WO2004069229A1 (en) * 2003-02-05 2004-08-19 Ipca Laboratories Limited Dual release anti-diabetic drugs and process of production thereof

Also Published As

Publication number Publication date
KR20060051510A (en) 2006-05-19
WO2006080630A1 (en) 2006-08-03
KR100705210B1 (en) 2007-04-06

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Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase